iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oan-073672

UUCD1 version

UUC-OrA-00242

Ensembl Protein ID

ENSOANP00000011888.2

UniProt Accession

F6W0S0; F6W0S0_ORNAN

Protein Name

Uncharacterized protein

Gene Name

CISH

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000007470.2	ENSOANT00000011890.2	ENSOANP00000011888.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	1.30e-14	54.0	212	253

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 7    lrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlyedyq 53
           + ++ +SLqhLCRl+I+++++      +d+LPLPk++ dYL+++++q
   Q: 212  RKNSAPSLQHLCRLRINKLTKE-----VDQLPLPKRMGDYLKQYPFQ 253
           67899****************9.....8****************986 PP

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

MILSVQGPHL FLEEENIRRL SFSHGADELQ EQVMQPLSIT AFQEESAPSQ VAPRLENDLP 60
MVRDPEEDLL CIAKTFSYLR ESGWYWGSIT ASEAKQHLQK MPEGTFLVRD STHPSYLFTL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATCCCGTTCG GGACCAGATC ATTTCTCTCT CCCAAGTTCC TGAGCCTAAA CCGAGAGGTT 60
TTCCAGGGCA GGCTTCTCCG TGTCCCTAAG GGAGCAGACA GGACGGTGGT CGCAGCGATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR028425--CIS
IPR000980--SH2
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF07525--SOCS_box

PRINTS

PR00401--SH2DOMAIN

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005886--C:plasma membrane
GO:0004860--F:protein kinase inhibitor activity
GO:0019221--P:cytokine-mediated signaling pathway
GO:0035556--P:intracellular signal transduction
GO:0046627--P:negative regulation of insulin receptor signaling pathway
GO:0046426--P:negative regulation of JAK-STAT cascade
GO:0006469--P:negative regulation of protein kinase activity
GO:0007205--P:protein kinase C-activating G-protein coupled receptor signaling pathway
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001189	Ailuropoda melanoleuca	66.93	3.00e-85	307.00
IUUC-Aca-004372	Anolis carolinensis	73.54	1.00e-100	358.00
IUUC-Ame-010787	Astyanax mexicanus	45.74	1.00e-52	198.00
IUUC-Bta-012826	Bos taurus	66.80	1.00e-90	324.00
IUUC-Cel-018643	Caenorhabditis elegans	26.54	1.00e-07	48.50
IUUC-Cja-020004	Callithrix jacchus	66.01	7.00e-83	299.00
IUUC-Cfa-020150	Canis familiaris	65.48	1.00e-83	301.00
IUUC-Csa-023173	Chlorocebus sabaeus	71.24	1.00e-84	305.00
IUUC-Dre-028606	Danio rerio	42.86	5.00e-35	140.00
IUUC-Dno-028956	Dasypus novemcinctus	68.53	6.00e-86	309.00
IUUC-Dor-030148	Dipodomys ordii	57.81	1.00e-74	272.00
IUUC-Ete-032313	Echinops telfairi	67.50	2.00e-81	294.00
IUUC-Eca-033422	Equus caballus	66.02	1.00e-90	325.00
IUUC-Eeu-034806	Erinaceus europaeus	69.13	1.00e-80	291.00
IUUC-Fca-036374	Felis catus	66.41	7.00e-91	325.00
IUUC-Fal-036801	Ficedula albicollis	75.98	3.00e-103	367.00
IUUC-Gmo-038483	Gadus morhua	40.00	5.00e-36	143.00
IUUC-Gga-040891	Gallus gallus	76.77	5.00e-98	349.00
IUUC-Ggo-045511	Gorilla gorilla	70.82	2.00e-84	304.00
IUUC-Hsa-046678	Homo sapiens	66.15	3.00e-87	313.00
IUUC-Itr-048397	Ictidomys tridecemlineatus	67.18	5.00e-91	326.00
IUUC-Lch-050555	Latimeria chalumnae	57.87	9.00e-76	275.00
IUUC-Laf-054141	Loxodonta africana	65.64	5.00e-94	336.00
IUUC-Mcc-055401	Macaca mulatta	70.82	5.00e-84	303.00
IUUC-Meu-056592	Macropus eugenii	76.92	3.00e-98	350.00
IUUC-Mga-059515	Meleagris gallopavo	76.52	1.00e-94	338.00
IUUC-Mmr-060848	Microcebus murinus	70.26	1.00e-84	305.00
IUUC-Mdo-062720	Monodelphis domestica	75.59	2.00e-100	357.00
IUUC-Mmu-063348	Mus musculus	66.02	6.00e-90	322.00
IUUC-Mpu-065834	Mustela putorius furo	66.80	2.00e-86	311.00
IUUC-Mlu-067687	Myotis lucifugus	66.67	9.00e-82	295.00
IUUC-Nle-069277	Nomascus leucogenys	66.15	7.00e-87	312.00
IUUC-Ont-071890	Oreochromis niloticus	49.73	6.00e-38	149.00
IUUC-Ocu-073875	Oryctolagus cuniculus	69.96	8.00e-84	302.00
IUUC-Ola-087140	Oryzias latipes	47.06	4.00e-27	113.00
IUUC-Oga-087943	Otolemur garnettii	67.18	4.00e-89	320.00
IUUC-Oar-090194	Ovis aries	69.87	2.00e-86	311.00
IUUC-Ptr-090934	Pan troglodytes	70.39	4.00e-84	303.00
IUUC-Pan-092121	Papio anubis	66.54	5.00e-87	313.00
IUUC-Psi-093733	Pelodiscus sinensis	76.52	2.00e-103	367.00
IUUC-Pfo-096313	Poecilia formosa	48.72	7.00e-45	172.00
IUUC-Pab-098439	Pongo abelii	66.54	2.00e-87	314.00
IUUC-Pca-101010	Procavia capensis	65.25	6.00e-92	329.00
IUUC-Pva-103112	Pteropus vampyrus	64.86	3.00e-87	313.00
IUUC-Rno-105917	Rattus norvegicus	63.32	1.00e-85	308.00
IUUC-Sha-106954	Sarcophilus harrisii	75.88	2.00e-102	363.00
IUUC-Smo-109292	Selaginella moellendorffii	29.51	2.20e-01	30.00
IUUC-Sar-113001	Sorex araneus	65.87	3.00e-82	297.00
IUUC-Ssc-115922	Sus scrofa	69.23	5.00e-48	182.00
IUUC-Tgu-117338	Taeniopygia guttata	78.54	2.00e-104	370.00
IUUC-Tru-118511	Takifugu rubripes	45.61	4.00e-33	133.00
IUUC-Tsy-119434	Tarsius syrichta	70.26	5.00e-86	309.00
IUUC-Ttr-128340	Tursiops truncatus	54.90	2.00e-59	221.00
IUUC-Vpa-130443	Vicugna pacos	66.41	4.00e-91	327.00
IUUC-Xtr-131784	Xenopus tropicalis	54.34	6.00e-73	266.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence