iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
TRANSFAC	miRNAMap	RAID2
Protein-protein Interaction
HINT
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	2.20e-15	56.6	209	256

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 1    lsklwllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlyedyq 53
           l++++++rs+ rSLqhLCRl+I+r++++     +d+LPLP+++ dYL+++++q
   Q: 209  LVQPFVRRSSARSLQHLCRLVINRLVTD-----VDCLPLPRRMADYLRQYPFQ 256
           57999***********************.....8****************986 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MVLCVQGSCP LLVVEQIGQR PLWAQSLELP GPAMQPLPTG AFPEEVTEET PVQSENEPKV 60
LDPEGDLLCI AKTFSYLRES GWYWGSITAS EARQHLQKMP EGTFLVRDST HPSYLFTLSV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGAGGCGCCT AGCCCCGCCC CACTCTCCCG GTCCGTCCCC CCTCGTTCTT CCAAGCTGCT 60
CGCACCACAG CCTTTCAGTC CCCGATCGCC GCCGGTACGC CCCGGGACCC TGACCTTCGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR028425--CIS
IPR000980--SH2
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF07525--SOCS_box

PRINTS

PR00401--SH2DOMAIN

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005622--C:intracellular
GO:0005886--C:plasma membrane
GO:0035556--P:intracellular signal transduction
GO:0007205--P:protein kinase C-activating G-protein coupled receptor signaling pathway
GO:0016567--P:protein ubiquitination

KEGG

rno:83681

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001189	Ailuropoda melanoleuca	90.87	2.00e-119	421.00
IUUC-Aca-004372	Anolis carolinensis	63.46	1.00e-87	315.00
IUUC-Ame-010787	Astyanax mexicanus	45.53	8.00e-50	189.00
IUUC-Bta-012826	Bos taurus	89.49	2.00e-127	447.00
IUUC-Cja-020004	Callithrix jacchus	88.76	9.00e-113	399.00
IUUC-Cfa-020150	Canis familiaris	89.56	1.00e-111	395.00
IUUC-Csa-023173	Chlorocebus sabaeus	88.76	7.00e-112	396.00
IUUC-Dre-028606	Danio rerio	43.02	7.00e-33	133.00
IUUC-Dno-028956	Dasypus novemcinctus	86.72	2.00e-120	424.00
IUUC-Dor-030148	Dipodomys ordii	73.54	5.00e-101	360.00
IUUC-Ete-032313	Echinops telfairi	82.35	3.00e-101	361.00
IUUC-Eca-033422	Equus caballus	92.22	3.00e-131	461.00
IUUC-Eeu-034806	Erinaceus europaeus	89.56	4.00e-108	384.00
IUUC-Fca-036374	Felis catus	91.83	3.00e-123	434.00
IUUC-Fal-036801	Ficedula albicollis	64.62	1.00e-84	306.00
IUUC-Gmo-038483	Gadus morhua	37.98	3.00e-35	141.00
IUUC-Gga-040891	Gallus gallus	65.64	7.00e-81	293.00
IUUC-Gac-042147	Gasterosteus aculeatus	39.77	7.00e-35	140.00
IUUC-Ggo-045511	Gorilla gorilla	88.40	1.00e-109	389.00
IUUC-Hsa-046678	Homo sapiens	88.37	1.00e-113	402.00
IUUC-Itr-048397	Ictidomys tridecemlineatus	94.16	4.00e-133	467.00
IUUC-Lch-050555	Latimeria chalumnae	55.89	2.00e-70	258.00
IUUC-Laf-054141	Loxodonta africana	87.60	2.00e-122	431.00
IUUC-Mcc-055401	Macaca mulatta	87.95	4.00e-110	390.00
IUUC-Meu-056592	Macropus eugenii	69.48	2.00e-91	328.00
IUUC-Mga-059515	Meleagris gallopavo	73.50	2.00e-77	281.00
IUUC-Mmr-060848	Microcebus murinus	92.37	3.00e-119	421.00
IUUC-Mdo-062720	Monodelphis domestica	66.93	3.00e-91	327.00
IUUC-Mmu-063348	Mus musculus	96.11	1.00e-144	504.00
IUUC-Mpu-065834	Mustela putorius furo	90.66	6.00e-122	429.00
IUUC-Mlu-067687	Myotis lucifugus	85.99	1.00e-101	362.00
IUUC-Nle-069277	Nomascus leucogenys	87.21	4.00e-113	400.00
IUUC-Ont-071890	Oreochromis niloticus	47.12	3.00e-37	148.00
IUUC-Oan-073672	Ornithorhynchus anatinus	64.86	2.00e-85	308.00
IUUC-Ocu-073875	Oryctolagus cuniculus	91.97	6.00e-123	433.00
IUUC-Ola-087140	Oryzias latipes	43.05	6.00e-25	106.00
IUUC-Oga-087943	Otolemur garnettii	89.88	1.00e-121	428.00
IUUC-Oar-090194	Ovis aries	88.49	8.00e-122	429.00
IUUC-Ptr-090934	Pan troglodytes	89.16	3.00e-110	390.00
IUUC-Pan-092121	Papio anubis	87.60	2.00e-114	404.00
IUUC-Psi-093733	Pelodiscus sinensis	61.60	8.00e-81	292.00
IUUC-Pfo-096313	Poecilia formosa	48.74	3.00e-43	168.00
IUUC-Pab-098439	Pongo abelii	87.98	2.00e-112	398.00
IUUC-Pca-101010	Procavia capensis	87.60	3.00e-121	427.00
IUUC-Pva-103112	Pteropus vampyrus	90.27	5.00e-126	443.00
IUUC-Sha-106954	Sarcophilus harrisii	65.77	3.00e-91	327.00
IUUC-Smo-109292	Selaginella moellendorffii	31.15	2.20e-01	30.40
IUUC-Sar-113001	Sorex araneus	89.96	5.00e-116	410.00
IUUC-Ssc-115922	Sus scrofa	89.36	1.00e-64	238.00
IUUC-Tgu-117338	Taeniopygia guttata	65.34	2.00e-82	298.00
IUUC-Tru-118511	Takifugu rubripes	45.51	2.00e-32	132.00
IUUC-Tsy-119434	Tarsius syrichta	91.16	4.00e-114	403.00
IUUC-Ttr-128340	Tursiops truncatus	76.65	2.00e-85	308.00
IUUC-Vpa-130443	Vicugna pacos	90.66	3.00e-134	470.00
IUUC-Xtr-131784	Xenopus tropicalis	53.85	2.00e-67	248.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence