iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Bta-013302

Ensembl Protein ID

ENSBTAP00000033573.3

UniProt Accession

Q2KJE0; TAXB1_BOVIN

Genbank Protein ID

AAI05390.1

Protein Name

Tax1-binding protein 1 homolog

Genbank Nucleotide ID

BC105389

Gene Name

TAX1BP1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000019020.5	ENSBTAT00000033663.3	ENSBTAP00000033573.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/ZnF/UBZ	7.30e-17	61.3	783	809

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/ZnF/UBZ

   S: 2    lvCPvCqkm....vdqtdfeeHlDeCl 24
           +vCP+C+++    +dq+ fe+H+++++
   Q: 783  KVCPMCSEQfppdYDQQVFERHVQTHF 809
           79************************8 PP

Organism

Bos taurus

Functional Description
(View)

Inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degraded by caspase-3-like family proteins upon TNF-induced apoptosis. May also play a role in the pro-inflammatory cytokine IL-1 signaling cascade (By similarity).

Protein Sequence
(Fasta)

MTSFQEVPLQ TSNFAHVIFQ NVAKSYLPNA HLECHYTLTP YIHPHPKDWV GIFKVGWSTA 60
RDYYTFLWSP MPEHYVEGSA VNCELAFQGY YLPNDDGEFY QFCYVTHKGE IRGASTPFQF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGAGGCTGAT GGCGGCTGAA GCTCGGAAAC CTCTTTAACA CTCCACTCTT CCCGAGAGTT 60
CCTCACTCGG TAAGCGCCTC TCCAAGCCGG CCCCGGCGCC TCGCGTGGGG TGGACGTCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0053--Apoptosis
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR012852--CALCOCO1-like

Pfam

PF07888--CALCOCO1

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0046872--F:metal ion binding
GO:0006915--P:apoptotic process
GO:0032088--P:negative regulation of NF-kappaB transcription factor activity

KEGG

bta:535589

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001679	Ailuropoda melanoleuca	90.70	0.00e+00	1482.00
IUUC-Apl-003483	Anas platyrhynchos	71.14	0.00e+00	1006.00
IUUC-Aca-004388	Anolis carolinensis	69.37	0.00e+00	1055.00
IUUC-Ame-011597	Astyanax mexicanus	52.84	0.00e+00	768.00
IUUC-Cja-019115	Callithrix jacchus	89.85	0.00e+00	1462.00
IUUC-Cfa-020964	Canis familiaris	92.05	0.00e+00	1493.00
IUUC-Cpo-021321	Cavia porcellus	86.32	0.00e+00	1383.00
IUUC-Csa-023834	Chlorocebus sabaeus	87.39	0.00e+00	1409.00
IUUC-Cho-024833	Choloepus hoffmanni	72.58	0.00e+00	1092.00
IUUC-Cin-025652	Ciona intestinalis	39.57	3.00e-33	134.00
IUUC-Csv-026309	Ciona savignyi	29.64	5.00e-38	151.00
IUUC-Cne-026777	Cryptococcus neoformans	28.85	2.10e-01	31.20
IUUC-Dre-028589	Danio rerio	51.50	0.00e+00	716.00
IUUC-Dno-030000	Dasypus novemcinctus	89.60	0.00e+00	1434.00
IUUC-Dor-030372	Dipodomys ordii	76.38	0.00e+00	847.00
IUUC-Ete-032476	Echinops telfairi	68.19	0.00e+00	784.00
IUUC-Eca-033369	Equus caballus	91.92	0.00e+00	1437.00
IUUC-Eeu-034551	Erinaceus europaeus	87.24	0.00e+00	959.00
IUUC-Fca-036201	Felis catus	91.19	0.00e+00	1477.00
IUUC-Fal-036858	Ficedula albicollis	70.93	0.00e+00	1136.00
IUUC-Gmo-038559	Gadus morhua	50.06	0.00e+00	703.00
IUUC-Gga-040410	Gallus gallus	72.01	0.00e+00	1138.00
IUUC-Gac-041455	Gasterosteus aculeatus	49.58	0.00e+00	717.00
IUUC-Ggo-044630	Gorilla gorilla	87.42	0.00e+00	1414.00
IUUC-Hsa-046382	Homo sapiens	88.37	0.00e+00	1427.00
IUUC-Itr-048080	Ictidomys tridecemlineatus	91.70	0.00e+00	946.00
IUUC-Lch-050570	Latimeria chalumnae	60.93	0.00e+00	890.00
IUUC-Loc-052138	Lepisosteus oculatus	53.50	0.00e+00	775.00
IUUC-Laf-053961	Loxodonta africana	88.67	0.00e+00	1444.00
IUUC-Mcc-055567	Macaca mulatta	90.94	0.00e+00	1488.00
IUUC-Meu-056498	Macropus eugenii	59.09	1.00e-128	453.00
IUUC-Mga-059976	Meleagris gallopavo	71.81	0.00e+00	1118.00
IUUC-Mmr-061120	Microcebus murinus	89.15	0.00e+00	1454.00
IUUC-Mdo-062786	Monodelphis domestica	74.52	0.00e+00	1167.00
IUUC-Mmu-064335	Mus musculus	85.84	0.00e+00	1392.00
IUUC-Mpu-065955	Mustela putorius furo	89.88	0.00e+00	1281.00
IUUC-Mlu-067346	Myotis lucifugus	89.47	0.00e+00	1452.00
IUUC-Nle-070020	Nomascus leucogenys	88.98	0.00e+00	1444.00
IUUC-Opr-070912	Ochotona princeps	89.56	0.00e+00	939.00
IUUC-Ont-072077	Oreochromis niloticus	50.24	0.00e+00	701.00
IUUC-Oan-072766	Ornithorhynchus anatinus	75.57	0.00e+00	1205.00
IUUC-Ocu-073890	Oryctolagus cuniculus	89.47	0.00e+00	1401.00
IUUC-Ola-086797	Oryzias latipes	50.24	0.00e+00	717.00
IUUC-Oga-088654	Otolemur garnettii	88.49	0.00e+00	1411.00
IUUC-Oar-089818	Ovis aries	97.80	0.00e+00	1579.00
IUUC-Ptr-091003	Pan troglodytes	88.00	0.00e+00	1426.00
IUUC-Pan-092314	Papio anubis	90.82	0.00e+00	1482.00
IUUC-Psi-093572	Pelodiscus sinensis	73.85	0.00e+00	1125.00
IUUC-Pma-094610	Petromyzon marinus	34.32	2.00e-40	160.00
IUUC-Pfo-097213	Poecilia formosa	50.71	0.00e+00	726.00
IUUC-Pab-097686	Pongo abelii	87.27	0.00e+00	1404.00
IUUC-Pca-100726	Procavia capensis	82.44	9.00e-104	371.00
IUUC-Pva-102509	Pteropus vampyrus	72.62	0.00e+00	1068.00
IUUC-Rno-105535	Rattus norvegicus	84.72	0.00e+00	1345.00
IUUC-Sha-107520	Sarcophilus harrisii	71.11	0.00e+00	1129.00
IUUC-Sja-107809	Schizosaccharomyces japonicus	34.21	1.40e-01	31.20
IUUC-Sar-113699	Sorex araneus	83.97	0.00e+00	1335.00
IUUC-Ssc-115399	Sus scrofa	91.48	2.00e-169	587.00
IUUC-Tgu-116486	Taeniopygia guttata	70.45	0.00e+00	1129.00
IUUC-Tru-118050	Takifugu rubripes	48.16	0.00e+00	667.00
IUUC-Tsy-118822	Tarsius syrichta	87.76	0.00e+00	1476.00
IUUC-Tni-120117	Tetraodon nigroviridis	46.12	0.00e+00	662.00
IUUC-Tre-122132	Trichoderma reesei	28.38	2.50e-02	34.70
IUUC-Tbe-127368	Tupaia belangeri	71.12	6.00e-144	504.00
IUUC-Ttr-128751	Tursiops truncatus	86.68	0.00e+00	937.00
IUUC-Vpa-130362	Vicugna pacos	87.11	0.00e+00	1158.00
IUUC-Xtr-132419	Xenopus tropicalis	60.87	0.00e+00	927.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence