iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cpo-021825

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02005691

Gene Name

KLHL41

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000004968.3	ENSCPOT00000005022.2	ENSCPOP00000004472.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	4.40e-17	62.2	34	100
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	4.70e-13	48.1	132	163

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 2    DvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkldene 69
           D++l+ g++  ++h+++L+a+S++F+  fl++  e k k++++++ v+p v+  +l++lY+ ++d+n+
   Q: 34   DCTLKAGDKSLPCHRLILSACSPYFREYFLSDIAEEK-KKEMVLDNVDPAVLDLILRYLYSASIDLND 100
           9*********************************999.99999999*******************986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhFk 32
           + Ncl+ilr++ l+dcp+L+++a++f+++ F+
   Q: 132  PGNCLAILRLGLLLDCPRLALSAREFVSDRFP 163
           56***************************996 PP

Organism

Cavia porcellus

Protein Sequence
(Fasta)

MDSQRELAEE LRLYQSTLLQ DGLKDLLDEK KFIDCTLKAG DKSLPCHRLI LSACSPYFRE 60
YFLSDIAEEK KKEMVLDNVD PAVLDLILRY LYSASIDLND GNVQDIFALA SRFQIPSVFT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGATTCCC AGCGGGAACT TGCCGAGGAA CTGCGGCTTT ACCAATCCAC CCTTCTCCAG 60
GACGGTCTCA AAGATCTCCT GGATGAGAAG AAATTCATCG ACTGCACCCT AAAAGCGGGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030571--KLHL41
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005856--C:cytoskeleton
GO:0005829--C:cytosol
GO:0031430--C:M band
GO:0005634--C:nucleus
GO:0005886--C:plasma membrane
GO:0033017--C:sarcoplasmic reticulum membrane
GO:0016567--P:protein ubiquitination
GO:0045661--P:regulation of myoblast differentiation
GO:2000291--P:regulation of myoblast proliferation
GO:2001014--P:regulation of skeletal muscle cell differentiation
GO:0045214--P:sarcomere organization
GO:0035914--P:skeletal muscle cell differentiation
GO:0048741--P:skeletal muscle fiber development

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002167	Ailuropoda melanoleuca	93.40	0.00e+00	1139.00
IUUC-Apl-003866	Anas platyrhynchos	83.33	0.00e+00	1016.00
IUUC-Ame-011172	Astyanax mexicanus	60.70	0.00e+00	749.00
IUUC-Bta-012925	Bos taurus	93.56	0.00e+00	1145.00
IUUC-Bdi-014115	Brachypodium distachyon	25.32	9.00e-13	67.80
IUUC-Cja-019348	Callithrix jacchus	93.07	0.00e+00	1141.00
IUUC-Cfa-020782	Canis familiaris	94.22	0.00e+00	1147.00
IUUC-Csa-023184	Chlorocebus sabaeus	92.32	0.00e+00	970.00
IUUC-Cin-025237	Ciona intestinalis	28.47	6.00e-68	251.00
IUUC-Dre-028278	Danio rerio	59.11	0.00e+00	764.00
IUUC-Dno-029516	Dasypus novemcinctus	91.91	0.00e+00	1133.00
IUUC-Dor-030850	Dipodomys ordii	91.88	0.00e+00	751.00
IUUC-Ete-032697	Echinops telfairi	91.91	0.00e+00	1102.00
IUUC-Eca-033714	Equus caballus	93.56	0.00e+00	1145.00
IUUC-Eeu-035245	Erinaceus europaeus	91.74	0.00e+00	1042.00
IUUC-Gmo-039392	Gadus morhua	57.14	0.00e+00	725.00
IUUC-Ggr-040041	Gaeumannomyces graminis	28.47	7.00e-07	48.10
IUUC-Gga-041106	Gallus gallus	83.00	0.00e+00	1032.00
IUUC-Gac-042252	Gasterosteus aculeatus	59.87	0.00e+00	761.00
IUUC-Ggo-044817	Gorilla gorilla	93.23	0.00e+00	1141.00
IUUC-Hsa-046620	Homo sapiens	93.23	0.00e+00	1141.00
IUUC-Lch-050477	Latimeria chalumnae	68.32	0.00e+00	841.00
IUUC-Loc-051955	Lepisosteus oculatus	70.63	0.00e+00	897.00
IUUC-Laf-053500	Loxodonta africana	94.06	0.00e+00	1148.00
IUUC-Mcc-055316	Macaca mulatta	93.07	0.00e+00	1141.00
IUUC-Mmr-061444	Microcebus murinus	93.73	0.00e+00	1145.00
IUUC-Mmu-064147	Mus musculus	93.56	0.00e+00	1149.00
IUUC-Mlu-067481	Myotis lucifugus	91.25	0.00e+00	1122.00
IUUC-Nle-069339	Nomascus leucogenys	93.40	0.00e+00	1143.00
IUUC-Opr-070703	Ochotona princeps	94.06	0.00e+00	1104.00
IUUC-Ont-072420	Oreochromis niloticus	58.80	0.00e+00	783.00
IUUC-Oan-073476	Ornithorhynchus anatinus	91.91	0.00e+00	1129.00
IUUC-Ocu-074248	Oryctolagus cuniculus	94.06	0.00e+00	1154.00
IUUC-Ola-086361	Oryzias latipes	60.33	0.00e+00	768.00
IUUC-Oar-090349	Ovis aries	92.90	0.00e+00	1139.00
IUUC-Pan-092069	Papio anubis	93.23	0.00e+00	1142.00
IUUC-Psi-093671	Pelodiscus sinensis	86.30	0.00e+00	1029.00
IUUC-Pfo-096122	Poecilia formosa	60.96	0.00e+00	796.00
IUUC-Pab-098711	Pongo abelii	93.07	0.00e+00	1140.00
IUUC-Pca-100495	Procavia capensis	85.15	0.00e+00	1020.00
IUUC-Pva-102401	Pteropus vampyrus	93.23	0.00e+00	1142.00
IUUC-Rno-105969	Rattus norvegicus	93.73	0.00e+00	1152.00
IUUC-Ssl-108403	Sclerotinia sclerotiorum	26.83	7.00e-06	44.30
IUUC-Sar-113405	Sorex araneus	90.26	0.00e+00	1096.00
IUUC-Tgu-116725	Taeniopygia guttata	83.50	0.00e+00	1051.00
IUUC-Tru-117743	Takifugu rubripes	59.04	0.00e+00	760.00
IUUC-Tsy-119225	Tarsius syrichta	87.29	0.00e+00	1053.00
IUUC-Tni-120547	Tetraodon nigroviridis	60.63	0.00e+00	778.00
IUUC-Ttr-128645	Tursiops truncatus	93.23	0.00e+00	1140.00
IUUC-Vpa-130714	Vicugna pacos	93.89	0.00e+00	1148.00
IUUC-Xtr-132144	Xenopus tropicalis	75.91	0.00e+00	940.00
IUUC-Xma-133253	Xiphophorus maculatus	62.27	0.00e+00	799.00
IUUC-Yli-134535	Yarrowia lipolytica	25.00	2.00e-06	47.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence