iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aml-001336

Ensembl Protein ID

ENSAMEP00000006040.1

UniProt Accession

G1LGK0; G1LGK0_AILME

Genbank Protein ID

ENSAMEP00000006040

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ACTA01035759

Gene Name

IFIH1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000005698.1	ENSAMET00000006289.1	ENSAMEP00000006040.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/CARD	1.50e-39	134.5	111	183

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/CARD

   S: 1    tdeeyrlllstlqdrvrklLdvtdvldkylseflleeekelilaaaetkgnmqaaelLLktLvqkegWfrefl 73
           t++e ++ll +lq++++++L+v+d+ld +++  ll++e++ ++ aae +gn++++++LL ++vqke+Wf+efl
   Q: 111  THDECLQLLTLLQPTLVDRLLVRDILDRCVEKKLLTNEDRSRICAAESNGNESGVRELLRRIVQKENWFSEFL 183
           689*********************************************************************6 PP

Organism

Ailuropoda melanoleuca

Protein Sequence
(Fasta)

KMSNGYSADG SFCHLISCFR ARVKTYIQVE PVLDYLNFLP DDVKEQIQRT AVNAGNMQAA 60
DQLLSALEKG GWPPGWARQF LVALQRAGSG LAARYLNPEL TDLPSPSSET THDECLQLLT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAGATGTCGA ACGGCTATTC CGCAGACGGG AGTTTCTGCC ATCTCATCTC ATGTTTCAGG 60
GCCAGAGTGA AAACGTACAT CCAGGTGGAG CCCGTTCTCG ACTACCTGAA CTTTCTGCCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc

Interpro

IPR031964--CARD_dom
IPR011029--DEATH-like_dom
IPR006935--Helicase/UvrB_N
IPR014001--Helicase_ATP-bd
IPR001650--Helicase_C
IPR027417--P-loop_NTPase
IPR021673--RLR_CTR

PROSITE

PS51192--HELICASE_ATP_BIND_1
PS51194--HELICASE_CTER
PS51789--RLR_CTR

Pfam

PF16739--CARD_2
PF00271--Helicase_C
PF04851--ResIII
PF11648--RIG-I_C-RD

SMART

SM00487--DEXDc
SM00490--HELICc

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0003677--F:DNA binding
GO:0003725--F:double-stranded RNA binding
GO:0016817--F:hydrolase activity, acting on acid anhydrides
GO:0043021--F:ribonucleoprotein complex binding
GO:0003727--F:single-stranded RNA binding
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0039530--P:MDA-5 signaling pathway
GO:0032727--P:positive regulation of interferon-alpha production
GO:0032728--P:positive regulation of interferon-beta production
GO:0016925--P:protein sumoylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003900	Anas platyrhynchos	60.06	0.00e+00	1149.00
IUUC-Aca-005329	Anolis carolinensis	58.62	0.00e+00	998.00
IUUC-Ame-011305	Astyanax mexicanus	48.02	0.00e+00	840.00
IUUC-Bta-012361	Bos taurus	80.82	0.00e+00	1558.00
IUUC-Cja-018760	Callithrix jacchus	82.68	0.00e+00	1540.00
IUUC-Cfa-020321	Canis familiaris	89.46	0.00e+00	1698.00
IUUC-Cpo-022450	Cavia porcellus	77.50	0.00e+00	1521.00
IUUC-Cre-022916	Chlamydomonas reinhardtii	33.33	2.00e-12	68.60
IUUC-Csa-024194	Chlorocebus sabaeus	84.82	0.00e+00	1547.00
IUUC-Cho-024364	Choloepus hoffmanni	74.21	0.00e+00	1036.00
IUUC-Dre-028305	Danio rerio	53.95	0.00e+00	705.00
IUUC-Dno-029831	Dasypus novemcinctus	82.59	0.00e+00	1588.00
IUUC-Dor-030410	Dipodomys ordii	74.28	0.00e+00	1182.00
IUUC-Ete-032950	Echinops telfairi	75.23	1.00e-180	626.00
IUUC-Eca-034279	Equus caballus	83.66	0.00e+00	1605.00
IUUC-Eeu-034678	Erinaceus europaeus	78.50	0.00e+00	1526.00
IUUC-Fca-035618	Felis catus	94.55	0.00e+00	1052.00
IUUC-Fal-037106	Ficedula albicollis	68.14	0.00e+00	962.00
IUUC-Gmo-038598	Gadus morhua	49.03	0.00e+00	654.00
IUUC-Gga-040467	Gallus gallus	59.48	0.00e+00	1147.00
IUUC-Gac-042316	Gasterosteus aculeatus	47.61	0.00e+00	802.00
IUUC-Ggo-045461	Gorilla gorilla	84.24	0.00e+00	1538.00
IUUC-Hsa-045771	Homo sapiens	84.14	0.00e+00	1535.00
IUUC-Itr-048762	Ictidomys tridecemlineatus	80.25	0.00e+00	1536.00
IUUC-Lch-049913	Latimeria chalumnae	64.75	0.00e+00	907.00
IUUC-Loc-052768	Lepisosteus oculatus	52.89	0.00e+00	940.00
IUUC-Laf-053933	Loxodonta africana	82.22	0.00e+00	1565.00
IUUC-Mcc-054695	Macaca mulatta	84.92	0.00e+00	1552.00
IUUC-Meu-056829	Macropus eugenii	71.76	0.00e+00	1074.00
IUUC-Mga-059205	Meleagris gallopavo	59.96	0.00e+00	1147.00
IUUC-Mvi-060497	Microbotryum violaceum	35.38	4.00e-16	80.90
IUUC-Mmr-060703	Microcebus murinus	82.69	0.00e+00	1536.00
IUUC-Mdo-063079	Monodelphis domestica	68.93	0.00e+00	1348.00
IUUC-Mmu-064066	Mus musculus	77.65	0.00e+00	1521.00
IUUC-Mpu-066261	Mustela putorius furo	93.39	0.00e+00	1797.00
IUUC-Mlu-068196	Myotis lucifugus	81.71	0.00e+00	1531.00
IUUC-Nle-069479	Nomascus leucogenys	82.10	0.00e+00	1504.00
IUUC-Opr-070717	Ochotona princeps	71.89	0.00e+00	1098.00
IUUC-Ont-071702	Oreochromis niloticus	46.44	0.00e+00	825.00
IUUC-Oan-073639	Ornithorhynchus anatinus	65.75	0.00e+00	1151.00
IUUC-Ocu-074521	Oryctolagus cuniculus	82.22	0.00e+00	1571.00
IUUC-Ola-086351	Oryzias latipes	45.75	0.00e+00	790.00
IUUC-Oga-088539	Otolemur garnettii	79.57	0.00e+00	1509.00
IUUC-Oar-090186	Ovis aries	81.01	0.00e+00	1529.00
IUUC-Ptr-090575	Pan troglodytes	81.61	0.00e+00	1490.00
IUUC-Pan-092371	Papio anubis	85.12	0.00e+00	1552.00
IUUC-Psi-093072	Pelodiscus sinensis	62.49	0.00e+00	1212.00
IUUC-Pma-094345	Petromyzon marinus	42.21	9.00e-88	317.00
IUUC-Pfo-096401	Poecilia formosa	51.67	0.00e+00	669.00
IUUC-Pab-097623	Pongo abelii	82.88	0.00e+00	1523.00
IUUC-Pca-100993	Procavia capensis	75.45	0.00e+00	1283.00
IUUC-Pva-102227	Pteropus vampyrus	78.40	0.00e+00	1455.00
IUUC-Rno-105198	Rattus norvegicus	76.41	0.00e+00	1525.00
IUUC-Sha-107622	Sarcophilus harrisii	71.11	0.00e+00	1367.00
IUUC-Spo-108161	Schizosaccharomyces pombe	27.59	2.30e-02	34.70
IUUC-Sar-113625	Sorex araneus	67.29	0.00e+00	707.00
IUUC-Tgu-117486	Taeniopygia guttata	59.13	0.00e+00	1088.00
IUUC-Tru-118445	Takifugu rubripes	46.44	0.00e+00	820.00
IUUC-Tsy-119512	Tarsius syrichta	81.23	0.00e+00	1466.00
IUUC-Tni-120711	Tetraodon nigroviridis	45.14	0.00e+00	811.00
IUUC-Tbe-127644	Tupaia belangeri	72.57	0.00e+00	1332.00
IUUC-Ttr-128989	Tursiops truncatus	78.58	0.00e+00	1528.00
IUUC-Vpa-130587	Vicugna pacos	79.43	0.00e+00	1261.00
IUUC-Xtr-132127	Xenopus tropicalis	52.56	0.00e+00	989.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence