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Tag Content
iUUCD ID IUUC-Tgu-116786
Ensembl Protein ID ENSTGUP00000010895.1
UniProt Accession H0ZJX6; H0ZJX6_TAEGU
Genbank Protein ID ENSTGUP00000010895
Protein Name Histone-lysine N-methyltransferase
Genbank Nucleotide ID ABQF01014927
Gene Name WHSC1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSTGUG00000010558.1 ENSTGUT00000011008.1 ENSTGUP00000010895.1
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/PHD 9.40e-16 57.6 839 879
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/PHD
   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCr 52
           +C vC +gg+    l++Ce C  +fHp+Cl+++    +p+ + w+C++Cr
   Q: 839  WCFVCSKGGS----LLCCESCPAAFHPDCLNIE----MPDGS-WYCNDCR 879
           8*********....*******************....9***8.******8 PP
   
Organism Taeniopygia guttata
Protein Sequence
(Fasta)
MDFSIKRSSQ LLTQKINCIK MKQVPEILGN TNGKPQNCEV NRECSVYLGK AQLSATLQEG 60
VMQKYNGHET LPFIPADKLK DLTSRVFNGE SGAQDAKLRF EPQEIKGVGT PPNTTPIKNG 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Tgu-116786|E3,PHD|Taeniopygia guttata
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGGACTTTA GCATCAAAAG AAGTTCTCAA CTGTTAACTC AAAAAATTAA CTGCATCAAA 60
ATGAAGCAGG TACCAGAGAT CCTTGGAAAT ACCAATGGGA AACCTCAGAA TTGTGAAGTG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Tgu-116786|E3,PHD|Taeniopygia guttata
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0238--DNA-binding
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR006560--AWS_dom
IPR009071--HMG_box_dom
IPR003616--Post-SET_dom
IPR000313--PWWP_dom
IPR001214--SET_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS51215--AWS
PS50118--HMG_BOX_2
PS50868--POST_SET
PS50812--PWWP
PS50280--SET
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2
PS50089--ZF_RING_2
Pfam

PF00505--HMG_box
PF00855--PWWP
PF00856--SET
SMART

SM00570--AWS
SM00398--HMG
SM00249--PHD
SM00508--PostSET
SM00293--PWWP
SM00184--RING
SM00317--SET
Gene Ontology

GO:0005634--C:nucleus
GO:0003682--F:chromatin binding
GO:0018024--F:histone-lysine N-methyltransferase activity
GO:0043565--F:sequence-specific DNA binding
GO:0008270--F:zinc ion binding
GO:0003289--P:atrial septum primum morphogenesis
GO:0003290--P:atrial septum secundum morphogenesis
GO:0060348--P:bone development
GO:0010452--P:histone H3-K36 methylation
GO:0034770--P:histone H4-K20 methylation
GO:0003149--P:membranous septum morphogenesis
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0048298--P:positive regulation of isotype switching to IgA isotypes
GO:2001032--P:regulation of double-strand break repair via nonhomologous end joining
GO:0070201--P:regulation of establishment of protein localization
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000229 Aegilops tauschii 58.33 3.00e-04 41.20
IUUC-Aml-002181 Ailuropoda melanoleuca 81.71 0.00e+00 2098.00
IUUC-Apl-003677 Anas platyrhynchos 96.40 0.00e+00 2518.00
IUUC-Aca-004278 Anolis carolinensis 83.50 0.00e+00 1496.00
IUUC-Ame-011932 Astyanax mexicanus 72.27 0.00e+00 1065.00
IUUC-Bta-012522 Bos taurus 77.05 0.00e+00 1986.00
IUUC-Cja-018908 Callithrix jacchus 80.03 0.00e+00 2059.00
IUUC-Cfa-020894 Canis familiaris 80.92 0.00e+00 2123.00
IUUC-Cpo-021982 Cavia porcellus 79.46 0.00e+00 2079.00
IUUC-Csa-023807 Chlorocebus sabaeus 80.63 0.00e+00 2090.00
IUUC-Cho-024405 Choloepus hoffmanni 60.68 3.00e-176 611.00
IUUC-Csv-026298 Ciona savignyi 37.54 2.00e-55 209.00
IUUC-Dre-027492 Danio rerio 73.67 0.00e+00 1111.00
IUUC-Dno-030020 Dasypus novemcinctus 77.42 0.00e+00 1825.00
IUUC-Dor-031103 Dipodomys ordii 73.12 0.00e+00 1844.00
IUUC-Dme-032193 Drosophila melanogaster 36.50 4.00e-119 422.00
IUUC-Ete-032488 Echinops telfairi 75.10 0.00e+00 1917.00
IUUC-Eca-034066 Equus caballus 82.28 0.00e+00 2167.00
IUUC-Eeu-035199 Erinaceus europaeus 63.57 0.00e+00 663.00
IUUC-Fca-035434 Felis catus 77.06 0.00e+00 1739.00
IUUC-Fal-037113 Ficedula albicollis 95.88 0.00e+00 2591.00
IUUC-Gmo-039686 Gadus morhua 68.43 0.00e+00 1029.00
IUUC-Gga-040273 Gallus gallus 93.30 0.00e+00 2471.00
IUUC-Gac-042123 Gasterosteus aculeatus 50.74 0.00e+00 1241.00
IUUC-Ggo-044643 Gorilla gorilla 80.45 0.00e+00 2108.00
IUUC-Hsa-046380 Homo sapiens 80.63 0.00e+00 2085.00
IUUC-Itr-048658 Ictidomys tridecemlineatus 85.96 0.00e+00 1328.00
IUUC-Lch-050217 Latimeria chalumnae 68.51 0.00e+00 1775.00
IUUC-Lpe-051661 Leersia perrieri 29.74 1.00e-11 65.50
IUUC-Loc-052766 Lepisosteus oculatus 59.06 0.00e+00 1314.00
IUUC-Laf-053780 Loxodonta africana 81.40 0.00e+00 2155.00
IUUC-Mcc-054928 Macaca mulatta 80.78 0.00e+00 2122.00
IUUC-Meu-056184 Macropus eugenii 77.98 0.00e+00 808.00
IUUC-Mga-059576 Meleagris gallopavo 93.48 0.00e+00 2457.00
IUUC-Mmr-061045 Microcebus murinus 81.16 0.00e+00 2141.00
IUUC-Mdo-062576 Monodelphis domestica 84.99 0.00e+00 2243.00
IUUC-Mmu-063640 Mus musculus 78.84 0.00e+00 2057.00
IUUC-Mac-065303 Musa acuminata 28.57 7.00e-11 62.40
IUUC-Mpu-066512 Mustela putorius furo 81.63 0.00e+00 2103.00
IUUC-Mlu-067280 Myotis lucifugus 75.65 0.00e+00 1035.00
IUUC-Nle-069896 Nomascus leucogenys 80.87 0.00e+00 2029.00
IUUC-Ont-072197 Oreochromis niloticus 74.07 0.00e+00 1051.00
IUUC-Oan-072724 Ornithorhynchus anatinus 82.48 0.00e+00 1399.00
IUUC-Ocu-074758 Oryctolagus cuniculus 78.14 0.00e+00 2018.00
IUUC-Obr-076753 Oryza brachyantha 54.84 2.00e-07 51.60
IUUC-Ogu-078030 Oryza glumaepatula 29.15 1.00e-12 67.00
IUUC-Olo-080702 Oryza longistaminata 41.47 1.00e-44 174.00
IUUC-Opu-083371 Oryza punctata 44.72 7.00e-46 179.00
IUUC-Oga-088702 Otolemur garnettii 81.20 0.00e+00 1869.00
IUUC-Oar-089736 Ovis aries 71.58 0.00e+00 1761.00
IUUC-Ptr-091055 Pan troglodytes 80.48 0.00e+00 2086.00
IUUC-Pan-092752 Papio anubis 88.18 0.00e+00 1311.00
IUUC-Psi-093620 Pelodiscus sinensis 91.37 0.00e+00 2431.00
IUUC-Pfo-097464 Poecilia formosa 50.52 0.00e+00 1203.00
IUUC-Pab-098051 Pongo abelii 80.78 0.00e+00 2119.00
IUUC-Pop-099927 Populus trichocarpa 28.27 2.00e-11 63.90
IUUC-Pca-100273 Procavia capensis 80.71 0.00e+00 2107.00
IUUC-Pva-102473 Pteropus vampyrus 70.49 0.00e+00 1761.00
IUUC-Rno-105056 Rattus norvegicus 78.98 0.00e+00 2069.00
IUUC-Sha-107494 Sarcophilus harrisii 85.35 0.00e+00 2211.00
IUUC-Sit-110333 Setaria italica 27.81 6.00e-10 58.90
IUUC-Sar-113310 Sorex araneus 80.06 0.00e+00 1655.00
IUUC-Ssc-116344 Sus scrofa 75.36 0.00e+00 1955.00
IUUC-Tru-117638 Takifugu rubripes 50.67 0.00e+00 1235.00
IUUC-Tsy-118937 Tarsius syrichta 86.40 0.00e+00 1394.00
IUUC-Tae-125237 Triticum aestivum 31.13 1.00e-05 42.70
IUUC-Tbe-127291 Tupaia belangeri 79.25 0.00e+00 1354.00
IUUC-Ttr-129017 Tursiops truncatus 72.57 0.00e+00 1533.00
IUUC-Xtr-132673 Xenopus tropicalis 68.72 0.00e+00 1801.00
IUUC-Xma-133695 Xiphophorus maculatus 68.06 0.00e+00 1022.00
Created Date 25-Jun-2017

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