iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
IID
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/CUE	4.20e-09	36.5	306	346

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/CUE

   S: 2    letaleqLkeiFPnldysviqvvLeantgsleaavnnLLegs 43
           ++++++++k+ FP ++ s i+++L ++t s++++vnnL  g+
   Q: 306  MDECAMRIKQSFPSFHLSAIRRDL-EKTRSQTTTVNNLKAGK 346
           689*********************.*************9875 PP

Organism

Caenorhabditis elegans

Protein Sequence
(Fasta)

MASPEASSSG NTEDLRIEDL FHQKRNEDTI AKIFSIIYAP VGLIILLIRV FLGFHTFIVA 60
CLLRKSAALR MHTLRIMCSI LGIVVEKSGH RDESARVLCA NHVSILDHLA VDILTPCLLP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AATGGCATCA CCAGAAGCAT CGTCTTCTGG AAATACAGAA GATCTTCGTA TCGAAGATTT 60
ATTCCATCAA AAACGAAATG AAGATACGAT TGCTAAAATA TTTTCGATTA TTTATGCTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR003892--CUE
IPR002123--Plipid/glycerol_acylTrfase

PROSITE

PS51140--CUE

SMART

SM00546--CUE
SM00563--PlsC

Gene Ontology

GO:0000839--C:Hrd1p ubiquitin ligase ERAD-L complex
GO:0030176--C:integral component of endoplasmic reticulum membrane
GO:0016746--F:transferase activity, transferring acyl groups
GO:0043130--F:ubiquitin binding
GO:0097027--F:ubiquitin-protein transferase activator activity
GO:0030433--P:ubiquitin-dependent ERAD pathway

KEGG

cel:CELE_F44B9.5

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002330	Ailuropoda melanoleuca	32.23	3.00e-31	128.00
IUUC-Apl-003946	Anas platyrhynchos	37.59	3.00e-41	160.00
IUUC-Bta-012397	Bos taurus	33.43	9.00e-42	162.00
IUUC-Cja-018775	Callithrix jacchus	29.13	4.00e-18	84.70
IUUC-Cfa-020710	Canis familiaris	34.18	2.00e-43	168.00
IUUC-Cpo-022111	Cavia porcellus	33.62	3.00e-41	161.00
IUUC-Csa-023411	Chlorocebus sabaeus	34.18	4.00e-43	167.00
IUUC-Dre-027938	Danio rerio	32.94	2.00e-43	169.00
IUUC-Dno-028873	Dasypus novemcinctus	33.33	8.00e-41	159.00
IUUC-Dor-030537	Dipodomys ordii	30.61	7.00e-32	130.00
IUUC-Ete-032422	Echinops telfairi	30.77	3.00e-17	81.60
IUUC-Eca-033757	Equus caballus	34.75	2.00e-40	158.00
IUUC-Eeu-034556	Erinaceus europaeus	29.13	2.00e-32	131.00
IUUC-Fca-035438	Felis catus	33.61	2.00e-42	164.00
IUUC-Fal-036911	Ficedula albicollis	37.68	8.00e-41	159.00
IUUC-Gmo-039147	Gadus morhua	33.53	4.00e-44	170.00
IUUC-Gga-041239	Gallus gallus	35.87	8.00e-46	176.00
IUUC-Gac-041814	Gasterosteus aculeatus	32.77	5.00e-46	177.00
IUUC-Ggo-044745	Gorilla gorilla	26.62	2.00e-23	102.00
IUUC-Hsa-046167	Homo sapiens	34.18	3.00e-43	167.00
IUUC-Itr-048661	Ictidomys tridecemlineatus	33.63	2.00e-40	159.00
IUUC-Lch-050576	Latimeria chalumnae	32.95	2.00e-36	144.00
IUUC-Loc-052028	Lepisosteus oculatus	34.30	6.00e-41	160.00
IUUC-Laf-053886	Loxodonta africana	33.33	3.00e-30	124.00
IUUC-Mcc-055399	Macaca mulatta	31.92	5.00e-34	137.00
IUUC-Meu-056355	Macropus eugenii	30.13	4.00e-13	68.20
IUUC-Mga-060065	Meleagris gallopavo	35.15	5.00e-41	160.00
IUUC-Mmu-064080	Mus musculus	32.67	9.00e-31	126.00
IUUC-Mpu-066233	Mustela putorius furo	34.18	2.00e-43	168.00
IUUC-Mlu-067489	Myotis lucifugus	33.62	6.00e-41	160.00
IUUC-Nle-070040	Nomascus leucogenys	29.26	2.00e-34	139.00
IUUC-Ont-071616	Oreochromis niloticus	32.93	8.00e-44	169.00
IUUC-Ocu-074618	Oryctolagus cuniculus	33.71	1.00e-41	162.00
IUUC-Ola-086583	Oryzias latipes	32.14	3.00e-23	101.00
IUUC-Oga-089100	Otolemur garnettii	33.51	2.00e-43	168.00
IUUC-Oar-089813	Ovis aries	33.43	8.00e-42	163.00
IUUC-Ptr-091436	Pan troglodytes	34.18	3.00e-43	167.00
IUUC-Pan-092755	Papio anubis	33.90	4.00e-43	167.00
IUUC-Psi-093736	Pelodiscus sinensis	41.73	1.00e-25	108.00
IUUC-Pma-094429	Petromyzon marinus	35.62	3.00e-44	171.00
IUUC-Pfo-097015	Poecilia formosa	32.05	2.00e-42	165.00
IUUC-Pab-098382	Pongo abelii	34.18	3.00e-43	167.00
IUUC-Pca-100900	Procavia capensis	29.37	3.00e-07	48.50
IUUC-Pva-103248	Pteropus vampyrus	26.89	3.00e-19	88.20
IUUC-Rno-105755	Rattus norvegicus	32.15	6.00e-31	127.00
IUUC-Sha-107434	Sarcophilus harrisii	32.08	4.00e-20	90.50
IUUC-Sar-113104	Sorex araneus	27.54	1.00e-09	55.50
IUUC-Ssc-116047	Sus scrofa	32.99	3.00e-30	124.00
IUUC-Tgu-117436	Taeniopygia guttata	36.68	3.00e-45	174.00
IUUC-Tru-118227	Takifugu rubripes	33.04	9.00e-44	169.00
IUUC-Tni-120873	Tetraodon nigroviridis	32.63	7.00e-44	169.00
IUUC-Ttr-128895	Tursiops truncatus	27.43	3.00e-24	105.00
IUUC-Xtr-131917	Xenopus tropicalis	38.21	8.00e-30	122.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence