iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aca-005331

Ensembl Protein ID

ENSACAP00000016711.3

UniProt Accession

H9GNT6; H9GNT6_ANOCA

Protein Name

Uncharacterized protein

Gene Name

MAP3K5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000016923.3	ENSACAT00000017041.3	ENSACAP00000016711.3

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
ULD/UDP/UBQ/UBQ_Other	87.79	0.00e+00	2094.00	IUUC-Hsa-046906

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MNDLSTKHMF FLLQMCTGNY IFLPYMITPH NKVYCCDSSF MKGLTELMQP NFELLLGPIC 60
LPLVDRFVQL LKVAQGSSSQ YFKESILNDI RKARNLYTGK ELAAELARIR QRVDNIELLS 120

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Nucleotide Sequence
(Fasta)

ATTAGACCAC ACTTTTCACT AGGTTTAGTG GCTGGGGATT ATTGGAGTTA TATTTGAAAC 60
ACATCTAAAG AGATCAGGTT CAGGAAGACA GCTATATCAT TACTTTAGAA AAAGGGACAA 120

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Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0808--Transferase

Interpro

IPR025136--DUF4071
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR013761--SAM/pointed
IPR008271--Ser/Thr_kinase_AS

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST

Pfam

PF13281--DUF4071
PF00069--Pkinase

SMART

SM00220--S_TKc

Gene Ontology

GO:1990604--C:IRE1-TRAF2-ASK1 complex
GO:1902911--C:protein kinase complex
GO:0005524--F:ATP binding
GO:0000287--F:magnesium ion binding
GO:0004709--F:MAP kinase kinase kinase activity
GO:0000187--P:activation of MAPK activity
GO:0000186--P:activation of MAPKK activity
GO:0070301--P:cellular response to hydrogen peroxide
GO:1902170--P:cellular response to reactive nitrogen species
GO:0070059--P:intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:0008631--P:intrinsic apoptotic signaling pathway in response to oxidative stress
GO:0007254--P:JNK cascade
GO:0038066--P:p38MAPK cascade
GO:0043280--P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043507--P:positive regulation of JUN kinase activity
GO:0045663--P:positive regulation of myoblast differentiation
GO:1901216--P:positive regulation of neuron death
GO:0097300--P:programmed necrotic cell death

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002318	Ailuropoda melanoleuca	88.01	0.00e+00	1912.00
IUUC-Apl-003713	Anas platyrhynchos	89.06	0.00e+00	1953.00
IUUC-Ame-011158	Astyanax mexicanus	75.32	0.00e+00	1682.00
IUUC-Bta-012770	Bos taurus	88.45	0.00e+00	1999.00
IUUC-Cja-019656	Callithrix jacchus	87.45	0.00e+00	1981.00
IUUC-Cfa-020488	Canis familiaris	87.76	0.00e+00	1984.00
IUUC-Cpo-022516	Cavia porcellus	86.23	0.00e+00	1916.00
IUUC-Cre-022653	Chlamydomonas reinhardtii	36.81	8.00e-30	124.00
IUUC-Csa-023104	Chlorocebus sabaeus	87.87	0.00e+00	2002.00
IUUC-Cho-024379	Choloepus hoffmanni	83.33	0.00e+00	1160.00
IUUC-Dre-028836	Danio rerio	75.15	0.00e+00	1683.00
IUUC-Dno-029842	Dasypus novemcinctus	86.40	0.00e+00	1948.00
IUUC-Dor-030990	Dipodomys ordii	88.95	0.00e+00	1737.00
IUUC-Ete-032693	Echinops telfairi	79.24	0.00e+00	1598.00
IUUC-Eca-033337	Equus caballus	87.79	0.00e+00	2021.00
IUUC-Eeu-034602	Erinaceus europaeus	72.59	0.00e+00	1569.00
IUUC-Fca-035954	Felis catus	87.55	0.00e+00	1758.00
IUUC-Fal-037358	Ficedula albicollis	88.22	0.00e+00	1990.00
IUUC-Gmo-038836	Gadus morhua	79.84	0.00e+00	1540.00
IUUC-Gga-040443	Gallus gallus	89.14	0.00e+00	2026.00
IUUC-Gac-041634	Gasterosteus aculeatus	76.68	0.00e+00	1727.00
IUUC-Ggo-045263	Gorilla gorilla	85.53	0.00e+00	1917.00
IUUC-Hsa-046906	Homo sapiens	87.79	0.00e+00	1998.00
IUUC-Itr-048449	Ictidomys tridecemlineatus	84.91	0.00e+00	972.00
IUUC-Lch-050213	Latimeria chalumnae	77.82	0.00e+00	1776.00
IUUC-Loc-051829	Lepisosteus oculatus	74.81	0.00e+00	1665.00
IUUC-Laf-053538	Loxodonta africana	87.43	0.00e+00	1970.00
IUUC-Mcc-054776	Macaca mulatta	87.87	0.00e+00	1997.00
IUUC-Mga-059636	Meleagris gallopavo	89.14	0.00e+00	2026.00
IUUC-Mmr-061323	Microcebus murinus	87.37	0.00e+00	1949.00
IUUC-Mdo-062146	Monodelphis domestica	87.94	0.00e+00	1943.00
IUUC-Mmu-064022	Mus musculus	86.83	0.00e+00	1976.00
IUUC-Mpu-066531	Mustela putorius furo	85.39	0.00e+00	1973.00
IUUC-Mlu-068181	Myotis lucifugus	86.74	0.00e+00	1982.00
IUUC-Nle-069758	Nomascus leucogenys	87.79	0.00e+00	2002.00
IUUC-Opr-070531	Ochotona princeps	81.11	0.00e+00	1374.00
IUUC-Ont-072014	Oreochromis niloticus	77.42	0.00e+00	1713.00
IUUC-Oan-073169	Ornithorhynchus anatinus	88.37	0.00e+00	1995.00
IUUC-Ocu-074050	Oryctolagus cuniculus	83.52	0.00e+00	1870.00
IUUC-Ola-086941	Oryzias latipes	79.82	0.00e+00	1432.00
IUUC-Oga-088796	Otolemur garnettii	86.77	0.00e+00	1965.00
IUUC-Oar-090445	Ovis aries	88.62	0.00e+00	2003.00
IUUC-Ptr-090846	Pan troglodytes	87.87	0.00e+00	2001.00
IUUC-Pan-091986	Papio anubis	87.87	0.00e+00	1999.00
IUUC-Psi-093805	Pelodiscus sinensis	88.79	0.00e+00	2116.00
IUUC-Pfo-097301	Poecilia formosa	77.59	0.00e+00	1738.00
IUUC-Pab-097662	Pongo abelii	87.70	0.00e+00	1999.00
IUUC-Pca-100755	Procavia capensis	67.77	0.00e+00	669.00
IUUC-Pva-102280	Pteropus vampyrus	78.53	0.00e+00	1740.00
IUUC-Rno-105547	Rattus norvegicus	86.50	0.00e+00	1948.00
IUUC-Sha-106859	Sarcophilus harrisii	87.60	0.00e+00	1910.00
IUUC-Sar-113714	Sorex araneus	76.02	0.00e+00	1656.00
IUUC-Tgu-117116	Taeniopygia guttata	87.78	0.00e+00	1979.00
IUUC-Tru-118088	Takifugu rubripes	77.00	0.00e+00	1769.00
IUUC-Tsy-119616	Tarsius syrichta	84.26	0.00e+00	1624.00
IUUC-Tni-120284	Tetraodon nigroviridis	75.23	0.00e+00	1724.00
IUUC-Tbe-127900	Tupaia belangeri	89.36	0.00e+00	819.00
IUUC-Ttr-128294	Tursiops truncatus	76.60	0.00e+00	1661.00
IUUC-Vpa-130470	Vicugna pacos	80.96	0.00e+00	1778.00
IUUC-Xtr-132396	Xenopus tropicalis	78.53	0.00e+00	1734.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence