iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ptr-091356

Ensembl Protein ID

ENSPTRP00000040300.4

UniProt Accession

H2R076; H2R076_PANTR

Genbank Protein ID

ENSPTRP00000040300

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AACZ03113072

Gene Name

KLHL14

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000023330.4	ENSPTRT00000047755.4	ENSPTRP00000040300.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	5.40e-12	45.9	33	148

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmelees..................................................ks 39
           +Dv+l  +g++f++hk+vLa++S++F++lf+++ + +                                                  + 
   Q: 33   CDVTLTAQGQQFHCHKAVLASCSQYFRSLFSSHPPLGggvggqdglgapkdqqqppqqqpsqqqqpppqeepgtpssspddklltspRA 121
           9*********************************9777***********************************************9977 PP
   S: 40   klmveikdvqpevfrallkFlYtgkld 66
            +  ++++ +   +r +l++lYt  ++
   Q: 122  INNLVLQGCSSIGLRLVLEYLYTANVT 148
           9999999****************9876 PP

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MSRSGDRTST FDPSHSDNLL HGLNLLWRKQ LFCDVTLTAQ GQQFHCHKAV LASCSQYFRS 60
LFSSHPPLGG GVGGQDGLGA PKDQQQPPQQ QPSQQQQPPP QEEPGTPSSS PDDKLLTSPR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCCAGAT CCGGGGACAG GACCTCCACC TTCGACCCCA GCCACAGCGA CAACCTGCTG 60
CACGGCCTCA ACCTGCTGTG GAGGAAGCAG CTGTTTTGCG ACGTGACCCT GACGGCCCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030584--KLHL14
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0016235--C:aggresome
GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005829--C:cytosol
GO:0005783--C:endoplasmic reticulum
GO:0043005--C:neuron projection
GO:0043025--C:neuronal cell body
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001196	Ailuropoda melanoleuca	87.92	8.00e-152	529.00
IUUC-Bta-012869	Bos taurus	91.72	0.00e+00	1099.00
IUUC-Cja-018731	Callithrix jacchus	92.36	0.00e+00	1108.00
IUUC-Cfa-020355	Canis familiaris	93.16	0.00e+00	1107.00
IUUC-Cpo-021612	Cavia porcellus	92.05	0.00e+00	1083.00
IUUC-Csa-023993	Chlorocebus sabaeus	92.85	0.00e+00	1087.00
IUUC-Dre-027629	Danio rerio	81.85	0.00e+00	994.00
IUUC-Dno-029185	Dasypus novemcinctus	92.38	0.00e+00	1104.00
IUUC-Fca-036303	Felis catus	92.69	0.00e+00	1100.00
IUUC-Fal-037175	Ficedula albicollis	88.06	0.00e+00	1061.00
IUUC-Gmo-038807	Gadus morhua	81.08	0.00e+00	983.00
IUUC-Gga-040750	Gallus gallus	88.91	0.00e+00	1053.00
IUUC-Gac-041372	Gasterosteus aculeatus	80.73	0.00e+00	983.00
IUUC-Ggo-044702	Gorilla gorilla	91.90	0.00e+00	1106.00
IUUC-Hsa-046282	Homo sapiens	94.90	0.00e+00	1091.00
IUUC-Lch-049564	Latimeria chalumnae	86.17	0.00e+00	1064.00
IUUC-Loc-051831	Lepisosteus oculatus	85.03	0.00e+00	1045.00
IUUC-Laf-054353	Loxodonta africana	92.99	0.00e+00	1106.00
IUUC-Mcc-055080	Macaca mulatta	90.22	8.00e-146	509.00
IUUC-Meu-056733	Macropus eugenii	79.74	0.00e+00	734.00
IUUC-Mmr-061263	Microcebus murinus	92.21	0.00e+00	1083.00
IUUC-Mdo-061930	Monodelphis domestica	83.57	0.00e+00	973.00
IUUC-Mmu-064251	Mus musculus	92.54	0.00e+00	1106.00
IUUC-Mpu-066871	Mustela putorius furo	93.00	0.00e+00	1108.00
IUUC-Mlu-067725	Myotis lucifugus	77.46	0.00e+00	725.00
IUUC-Nle-069427	Nomascus leucogenys	92.06	0.00e+00	1086.00
IUUC-Ont-072429	Oreochromis niloticus	82.48	0.00e+00	1006.00
IUUC-Ocu-074635	Oryctolagus cuniculus	92.38	0.00e+00	1103.00
IUUC-Ola-086870	Oryzias latipes	83.78	0.00e+00	1008.00
IUUC-Oga-088397	Otolemur garnettii	93.02	0.00e+00	1106.00
IUUC-Oar-089280	Ovis aries	92.93	0.00e+00	934.00
IUUC-Pan-092718	Papio anubis	92.85	0.00e+00	1087.00
IUUC-Psi-093970	Pelodiscus sinensis	87.10	0.00e+00	1000.00
IUUC-Pfo-096550	Poecilia formosa	82.51	0.00e+00	1003.00
IUUC-Pab-097802	Pongo abelii	92.21	0.00e+00	1077.00
IUUC-Pca-101125	Procavia capensis	88.08	0.00e+00	1026.00
IUUC-Pva-102888	Pteropus vampyrus	93.99	0.00e+00	1018.00
IUUC-Rno-105007	Rattus norvegicus	92.38	0.00e+00	1106.00
IUUC-Sar-113671	Sorex araneus	90.94	0.00e+00	1071.00
IUUC-Ssc-116060	Sus scrofa	92.38	0.00e+00	1108.00
IUUC-Tgu-116795	Taeniopygia guttata	80.92	0.00e+00	931.00
IUUC-Tru-118216	Takifugu rubripes	83.47	0.00e+00	1026.00
IUUC-Tsy-118816	Tarsius syrichta	99.36	0.00e+00	628.00
IUUC-Tni-120281	Tetraodon nigroviridis	75.49	0.00e+00	874.00
IUUC-Tbe-128057	Tupaia belangeri	88.73	0.00e+00	1030.00
IUUC-Ttr-128618	Tursiops truncatus	88.56	1.00e-146	513.00
IUUC-Vpa-130468	Vicugna pacos	90.31	0.00e+00	646.00
IUUC-Xtr-132753	Xenopus tropicalis	84.38	0.00e+00	1019.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence