iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

   S: 3    klwllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlyedyq 53
            ++l+++++r+Lq+LCR +I+ ++g+++l    ++PL+++L+dYL+++++q
   Q: 164  GAPLRQRRVRPLQELCRQRIVAAVGRENL---ARIPLNPVLRDYLSSFPFQ 211
           6789*************************...***************9986 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MVARNQVAAD NAISPASEPR RRPEPSSSSS SSSPAAPARP RPCPVVPAPA PGDTHFRTFR 60
SHSDYRRITR TSALLDACGF YWGPLSVHGA HERLRAEPVG TFLVRDSRQR NCFFALSVKM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCCGGACGCC CGGCTCACTG CCTCTGTCTC CCCCATCAGC GCAGCCCCGG ACGCTATGGC 60
CCACCCCTCC AGCTGGCCCC TCGAGTAGGA TGGTAGCACG TAACCAGGTG GCAGCCGACA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR028411--SOCS1
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF07525--SOCS_box

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0000932--C:P-body
GO:0019210--F:kinase inhibitor activity
GO:0071230--P:cellular response to amino acid stimulus
GO:0019221--P:cytokine-mediated signaling pathway
GO:0045444--P:fat cell differentiation
GO:0007259--P:JAK-STAT cascade
GO:0046627--P:negative regulation of insulin receptor signaling pathway
GO:0042512--P:negative regulation of tyrosine phosphorylation of Stat1 protein
GO:0042518--P:negative regulation of tyrosine phosphorylation of Stat3 protein
GO:0016567--P:protein ubiquitination
GO:0010534--P:regulation of activation of JAK2 kinase activity
GO:0050707--P:regulation of cytokine secretion
GO:0060334--P:regulation of interferon-gamma-mediated signaling pathway

KEGG

rno:252971

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001204	Ailuropoda melanoleuca	89.38	3.00e-78	283.00
IUUC-Apl-003313	Anas platyrhynchos	71.25	5.00e-71	259.00
IUUC-Aca-005109	Anolis carolinensis	69.62	4.00e-64	237.00
IUUC-Ame-011550	Astyanax mexicanus	48.75	6.00e-48	183.00
IUUC-Bta-013411	Bos taurus	84.30	9.00e-91	325.00
IUUC-Cja-019595	Callithrix jacchus	90.09	3.00e-92	330.00
IUUC-Cfa-020563	Canis familiaris	95.03	1.00e-88	318.00
IUUC-Cpo-021374	Cavia porcellus	85.71	4.00e-93	333.00
IUUC-Csa-023333	Chlorocebus sabaeus	87.32	8.00e-92	329.00
IUUC-Dre-028507	Danio rerio	46.79	1.00e-44	172.00
IUUC-Dno-029406	Dasypus novemcinctus	86.32	9.00e-91	325.00
IUUC-Ete-032399	Echinops telfairi	85.85	2.00e-90	324.00
IUUC-Eca-033519	Equus caballus	85.85	7.00e-88	316.00
IUUC-Fal-036726	Ficedula albicollis	71.43	2.00e-72	264.00
IUUC-Gmo-039667	Gadus morhua	49.56	1.00e-26	112.00
IUUC-Gga-040970	Gallus gallus	71.70	8.00e-71	259.00
IUUC-Gac-041838	Gasterosteus aculeatus	45.62	3.00e-36	144.00
IUUC-Ggo-045569	Gorilla gorilla	86.32	2.00e-92	330.00
IUUC-Hsa-046010	Homo sapiens	91.98	9.00e-92	328.00
IUUC-Itr-047995	Ictidomys tridecemlineatus	97.52	1.00e-90	325.00
IUUC-Lch-050219	Latimeria chalumnae	62.26	3.00e-62	231.00
IUUC-Loc-052494	Lepisosteus oculatus	57.23	3.00e-54	204.00
IUUC-Laf-054219	Loxodonta africana	94.85	3.00e-71	260.00
IUUC-Mcc-054830	Macaca mulatta	86.51	1.00e-91	328.00
IUUC-Meu-056565	Macropus eugenii	69.34	5.00e-78	283.00
IUUC-Mga-060153	Meleagris gallopavo	70.19	3.00e-70	257.00
IUUC-Mmr-061365	Microcebus murinus	97.52	7.00e-91	326.00
IUUC-Mdo-062824	Monodelphis domestica	80.75	4.00e-77	280.00
IUUC-Mmu-064120	Mus musculus	98.11	2.00e-95	341.00
IUUC-Mpu-066839	Mustela putorius furo	87.50	4.00e-92	330.00
IUUC-Mlu-067829	Myotis lucifugus	96.27	6.00e-90	323.00
IUUC-Nle-069592	Nomascus leucogenys	86.79	6.00e-88	316.00
IUUC-Ont-072173	Oreochromis niloticus	45.00	5.00e-38	150.00
IUUC-Oan-073586	Ornithorhynchus anatinus	53.27	6.00e-26	109.00
IUUC-Ocu-073996	Oryctolagus cuniculus	98.76	5.00e-92	329.00
IUUC-Oba-075150	Oryza barthii	29.41	7.10e-02	30.00
IUUC-Ola-087158	Oryzias latipes	46.88	9.00e-40	156.00
IUUC-Oga-088076	Otolemur garnettii	93.87	4.00e-92	330.00
IUUC-Ptr-091241	Pan troglodytes	91.51	2.00e-92	331.00
IUUC-Pan-091836	Papio anubis	86.32	5.00e-92	329.00
IUUC-Psi-093628	Pelodiscus sinensis	72.67	7.00e-72	263.00
IUUC-Pfo-097501	Poecilia formosa	45.28	5.00e-37	147.00
IUUC-Pab-098170	Pongo abelii	87.79	1.00e-91	328.00
IUUC-Pop-100072	Populus trichocarpa	30.77	2.40e-02	32.70
IUUC-Pva-102796	Pteropus vampyrus	87.79	3.00e-91	327.00
IUUC-Sha-107201	Sarcophilus harrisii	79.87	4.00e-73	266.00
IUUC-Ssc-116004	Sus scrofa	87.73	4.00e-92	330.00
IUUC-Tgu-116836	Taeniopygia guttata	71.43	2.00e-71	261.00
IUUC-Tru-118090	Takifugu rubripes	42.50	5.00e-36	143.00
IUUC-Tni-120719	Tetraodon nigroviridis	44.38	6.00e-33	133.00
IUUC-Vpa-130235	Vicugna pacos	86.98	2.00e-91	328.00
IUUC-Xtr-132610	Xenopus tropicalis	65.22	3.00e-66	244.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence