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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Mmu-063739
UUCD1 version UUC-MuM-00061
Ensembl Protein ID ENSMUSP00000099432.3
UniProt Accession Q9CZV8; A7YE80; Q3UMN2; Q571F7; Q8BZ95; FXL20_MOUSE
Genbank Protein ID ABU95014.1; BAB28039.1; BAC29349.1; BAE26066.1; BAD90157.1; CAM21260.1; CAM21260.1; CAM20406.1; CAM20406.1
Protein Name F-box/LRR-repeat protein 20; F-box and leucine-rich repeat protein 20; F-box/LRR-repeat protein 2-like
Genbank Nucleotide ID EF649694; AK012109; AK036217; AK144786; AK220232; AL591205; AL591209; AL591209; AL591205
Gene Name Fbxl20; Fbl2
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000020883.18 ENSMUST00000103143.9 ENSMUSP00000099432.3
ENSMUSG00000020883.18 ENSMUST00000147971.1 ENSMUSP00000123507.1
ENSMUSG00000020883.18 ENSMUST00000150378.7 ENSMUSP00000119003.1
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
AREsitemiRTarBasemicroRNATRANSFAC
RepTarRAID2
Protein-protein Interaction
IIDiRefIndexPINAHINT
Mentha
Post-translational Modifications (PTMs)
dbPAFPhosphositePlusdbPTMPhospho.ELM
UniProtPHOSIDA
Protein Expression/Proteomics
GPMDB
Status Reviewed
Details
Family Domain References (PMIDs)
E3 adaptor/Cullin RING/SCF/F-box F-box 18186301; 20130189
Classification
Family E-value Score Start End
E3 adaptor/Cullin RING/SCF/F-box 5.20e-05 24.4 20 68
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/SCF/F-box
   S: 98   pdaglldrlpeeilveilklldkeellraarvcrrwqelasqkalwktv 146
            +a + ++lp+e+l++i+++ld  +l+r+a+v+r w+ la + + w+++
   Q: 20   DEAVINKKLPKELLLRIFSFLDVVTLCRCAQVSRAWNVLALDGSNWQRI 68
           5677889******************************887778888865 PP
   
Organism Mus musculus
Functional Description
(View)

Functional Description


     Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Isoform 3 regulates neural transmission by binding and ubiquitinating RIMS1, a modulator of presynaptic plasticity.
 Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Isoform 3 regulates neural transmission by binding and ubiquitinating RIMS1, a modulator of presynaptic plasticity.
Protein Sequence
(Fasta)
MRRDVNGVTK SRFEMFSNSD EAVINKKLPK ELLLRIFSFL DVVTLCRCAQ VSRAWNVLAL 60
DGSNWQRIDL FDFQRDIEGR VVENISKRCG GFLRKLSLRG CLGVGDNALR TFAQNCRNIE 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-063739|E3,F-box|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GAGGTGTAGC CTCGCTGCCA GCTCCTGTGC AGAGCTGGCG CTACGTCCTC CTCTTAGCGC 60
AACCAGCTCC TGCCTTCTGG AGCCTGGCAC TGAGAGCCAT CCGCCCCGCA GGGGCCCCCC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-063739|E3,F-box|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0433--Leucine-rich repeat
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0833--Ubl conjugation pathway
Interpro

IPR001810--F-box_dom
IPR032675--L_dom-like
IPR001611--Leu-rich_rpt
IPR006553--Leu-rich_rpt_Cys-con_subtyp
PROSITE

PS50181--FBOX
Pfam

PF12937--F-box-like
PF13516--LRR_6
SMART

SM00256--FBOX
SM00367--LRR_CC
Gene Ontology

GO:0005737--C:cytoplasm
GO:0004842--F:ubiquitin-protein transferase activity
GO:0001662--P:behavioral fear response
KEGG mmu:72194
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001686 Ailuropoda melanoleuca 99.77 0.00e+00 882.00
IUUC-Atr-002749 Amborella trichopoda 32.89 2.00e-34 140.00
IUUC-Apl-003807 Anas platyrhynchos 93.69 0.00e+00 761.00
IUUC-Aca-004693 Anolis carolinensis 97.71 0.00e+00 868.00
IUUC-Afu-009050 Aspergillus fumigatus 28.47 1.00e-39 158.00
IUUC-Ani-009369 Aspergillus nidulans 29.17 9.00e-37 148.00
IUUC-Ame-011441 Astyanax mexicanus 91.99 0.00e+00 814.00
IUUC-Bta-012431 Bos taurus 99.77 0.00e+00 882.00
IUUC-Bci-013687 Botrytis cinerea 28.16 6.00e-31 129.00
IUUC-Bdi-015021 Brachypodium distachyon 29.23 3.00e-38 153.00
IUUC-Bra-017138 Brassica rapa 30.09 2.00e-35 143.00
IUUC-Cel-018603 Caenorhabditis elegans 49.40 4.00e-122 431.00
IUUC-Cja-019691 Callithrix jacchus 99.77 0.00e+00 882.00
IUUC-Cfa-020128 Canis familiaris 99.77 0.00e+00 882.00
IUUC-Cpo-021658 Cavia porcellus 99.77 0.00e+00 882.00
IUUC-Csa-024001 Chlorocebus sabaeus 99.77 0.00e+00 882.00
IUUC-Cho-024747 Choloepus hoffmanni 91.71 0.00e+00 775.00
IUUC-Cin-025116 Ciona intestinalis 58.47 1.00e-136 479.00
IUUC-Csv-025897 Ciona savignyi 57.54 2.00e-143 502.00
IUUC-Cne-027024 Cryptococcus neoformans 24.46 2.00e-20 94.40
IUUC-Cme-027303 Cyanidioschyzon merolae 26.21 7.00e-29 122.00
IUUC-Dre-027642 Danio rerio 92.43 0.00e+00 826.00
IUUC-Dno-029404 Dasypus novemcinctus 98.85 0.00e+00 875.00
IUUC-Dor-030309 Dipodomys ordii 75.27 5.00e-109 387.00
IUUC-Dme-032125 Drosophila melanogaster 58.75 5.00e-141 494.00
IUUC-Eca-033855 Equus caballus 99.53 0.00e+00 853.00
IUUC-Eeu-035124 Erinaceus europaeus 82.94 0.00e+00 666.00
IUUC-Fca-035529 Felis catus 99.26 0.00e+00 809.00
IUUC-Fal-037266 Ficedula albicollis 96.68 0.00e+00 827.00
IUUC-Gmo-039470 Gadus morhua 91.99 0.00e+00 819.00
IUUC-Ggr-039761 Gaeumannomyces graminis 28.54 7.00e-37 149.00
IUUC-Gac-041522 Gasterosteus aculeatus 92.45 0.00e+00 823.00
IUUC-Gma-043454 Glycine max 31.86 7.00e-36 145.00
IUUC-Ggo-044918 Gorilla gorilla 98.59 0.00e+00 838.00
IUUC-Hsa-045782 Homo sapiens 99.77 0.00e+00 882.00
IUUC-Itr-048431 Ictidomys tridecemlineatus 99.76 0.00e+00 853.00
IUUC-Lch-050194 Latimeria chalumnae 80.56 0.00e+00 702.00
IUUC-Lpe-051035 Leersia perrieri 30.66 2.00e-38 154.00
IUUC-Loc-052210 Lepisosteus oculatus 85.00 0.00e+00 729.00
IUUC-Lma-052999 Leptosphaeria maculans 28.47 1.00e-37 151.00
IUUC-Laf-054025 Loxodonta africana 99.31 0.00e+00 879.00
IUUC-Mcc-055833 Macaca mulatta 99.76 0.00e+00 852.00
IUUC-Meu-056907 Macropus eugenii 80.53 1.00e-131 462.00
IUUC-Mpo-057434 Magnaporthe poae 27.85 5.00e-35 142.00
IUUC-Mtr-058542 Medicago truncatula 28.96 4.00e-32 132.00
IUUC-Mla-058932 Melampsora laricipopulina 26.79 2.00e-25 111.00
IUUC-Mga-060160 Meleagris gallopavo 95.17 0.00e+00 837.00
IUUC-Mvi-060464 Microbotryum violaceum 26.11 5.00e-22 100.00
IUUC-Mmr-060909 Microcebus murinus 99.76 0.00e+00 852.00
IUUC-Mdo-062490 Monodelphis domestica 98.85 0.00e+00 876.00
IUUC-Mpu-066176 Mustela putorius furo 99.53 0.00e+00 853.00
IUUC-Mlu-068097 Myotis lucifugus 97.92 0.00e+00 854.00
IUUC-Nle-070106 Nomascus leucogenys 95.87 0.00e+00 823.00
IUUC-Ont-071380 Oreochromis niloticus 92.66 0.00e+00 827.00
IUUC-Oan-073599 Ornithorhynchus anatinus 98.82 0.00e+00 847.00
IUUC-Ocu-073864 Oryctolagus cuniculus 99.29 0.00e+00 850.00
IUUC-Obr-076836 Oryza brachyantha 28.25 2.00e-33 137.00
IUUC-Ogu-078431 Oryza glumaepatula 29.09 8.00e-38 152.00
IUUC-Oin-079837 Oryza indica 32.08 4.00e-39 156.00
IUUC-Olo-080891 Oryza longistaminata 29.06 6.00e-37 148.00
IUUC-Ome-082008 Oryza meridionalis 31.68 9.00e-36 145.00
IUUC-Oni-082538 Oryza nivara 31.08 6.00e-40 159.00
IUUC-Opu-083682 Oryza punctata 29.32 2.00e-37 150.00
IUUC-Oru-084309 Oryza rufipogon 32.08 4.00e-39 155.00
IUUC-Ola-086829 Oryzias latipes 92.20 0.00e+00 820.00
IUUC-Olu-087859 Ostreococcus lucimarinus 24.08 4.00e-08 53.10
IUUC-Oga-088755 Otolemur garnettii 99.05 0.00e+00 851.00
IUUC-Oar-089707 Ovis aries 99.77 0.00e+00 880.00
IUUC-Ptr-090904 Pan troglodytes 99.77 0.00e+00 882.00
IUUC-Pan-092252 Papio anubis 99.76 0.00e+00 853.00
IUUC-Psi-093859 Pelodiscus sinensis 97.64 0.00e+00 841.00
IUUC-Pma-094114 Petromyzon marinus 77.85 0.00e+00 699.00
IUUC-Ppa-096002 Physcomitrella patens 28.00 3.00e-26 113.00
IUUC-Pfo-097333 Poecilia formosa 91.97 0.00e+00 820.00
IUUC-Pab-098166 Pongo abelii 94.95 0.00e+00 827.00
IUUC-Pca-100608 Procavia capensis 95.64 0.00e+00 824.00
IUUC-Ppe-101524 Prunus persica 31.43 4.00e-35 142.00
IUUC-Pva-102787 Pteropus vampyrus 93.12 0.00e+00 813.00
IUUC-Pgr-103540 Puccinia graminis 25.75 7.00e-20 93.20
IUUC-Rno-105909 Rattus norvegicus 100.00 0.00e+00 883.00
IUUC-Sce-106382 Saccharomyces cerevisiae 25.42 4.00e-24 107.00
IUUC-Sha-107652 Sarcophilus harrisii 99.01 0.00e+00 811.00
IUUC-Sja-107860 Schizosaccharomyces japonicus 26.83 2.00e-26 113.00
IUUC-Ssl-108637 Sclerotinia sclerotiorum 29.19 1.00e-28 121.00
IUUC-Sly-111002 Solanum lycopersicum 30.29 2.00e-34 140.00
IUUC-Stu-112043 Solanum tuberosum 31.82 2.00e-34 139.00
IUUC-Sar-113053 Sorex araneus 99.22 0.00e+00 769.00
IUUC-Sbi-114065 Sorghum bicolor 32.25 5.00e-39 155.00
IUUC-Sre-115053 Sporisorium reilianum 25.35 2.00e-28 121.00
IUUC-Ssc-115902 Sus scrofa 99.77 0.00e+00 882.00
IUUC-Tru-117535 Takifugu rubripes 92.89 0.00e+00 830.00
IUUC-Tsy-119203 Tarsius syrichta 93.36 0.00e+00 768.00
IUUC-Tni-120555 Tetraodon nigroviridis 91.06 0.00e+00 820.00
IUUC-Tca-121600 Theobroma cacao 29.37 2.00e-38 153.00
IUUC-Tae-123291 Triticum aestivum 30.12 7.00e-32 132.00
IUUC-Ttr-128324 Tursiops truncatus 99.77 0.00e+00 882.00
IUUC-Uma-129602 Ustilago maydis 26.16 1.00e-27 119.00
IUUC-Vpa-130267 Vicugna pacos 98.82 0.00e+00 840.00
IUUC-Vvi-130903 Vitis vinifera 31.49 1.00e-32 134.00
IUUC-Xtr-131847 Xenopus tropicalis 89.39 0.00e+00 772.00
IUUC-Xma-133204 Xiphophorus maculatus 91.97 0.00e+00 820.00
Created Date 25-Jun-2017

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