iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tni-119983

UUCD1 version

UUC-TeN-01171

Ensembl Protein ID

ENSTNIP00000002023.1

UniProt Accession

H3C1A7; H3C1A7_TETNG

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTNIG00000018679.1	ENSTNIT00000000374.1	ENSTNIP00000002023.1
ENSTNIG00000018679.1	ENSTNIT00000022092.1	ENSTNIP00000021856.1
ENSTNIG00000018679.1	ENSTNIT00000003282.1	ENSTNIP00000003264.1
ENSTNIG00000018679.1	ENSTNIT00000002431.1	ENSTNIP00000001376.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	3.60e-55	187.7	169	651

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.....kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeef 84
           +G++N+gNtC++ +v+Q+L+++p +r+l+l+     +  ek++  + ++++ +++++l+ lf+ ++ s+++ v+p++ ++ l+++ +  
   Q: 169  VGIRNVGNTCWFSAVIQSLFHLPVFRRLVLNyrlseRILEKCKSHS-DKRNIAFMQELRCLFALMVGSTRRFVDPSAAVELLRDAFRTS 256
           6*******************************99887788887664.79999*******************************999985 PP
   S: 85   s.gyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldl 172
           + + + qD++Ef + lld le++++                     + ++   k+++++++lF g++ ++ k    +++    e+f ++
   Q: 257  EaQQSFQDVSEFSHKLLDWLEDAFQL------------------AANGSHAADKQQNPMVQLFYGTFVTERKL--EGKTLCNIEQFGQY 325
           4355669*****************22..................234567889999************88777..45666789****** PP
   S: 173  slpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdl 261
           +l+v+g +     +l +cLe  + e+e+e+   +++   ++++ + ++ +++klP+vL+++L+Rf+f+ + +++eki+kk+efp+ + +
   Q: 326  PLQVNGFN-----NLYECLEGAMVEKEIES---LHS---DHSVASGRERWFEKLPPVLTFELSRFEFNTQLGRPEKIHKKLEFPQVIFM 403
           ********.....9***********99995...554...556778899***************************************** PP
   S: 262  spfcts.....peekqke....................................................................... 274
           ++++++           e                                                                       
   Q: 404  DRYLHKnikqtH-----Errgevkklkeelaalqqklecyrnygsgptkypladmlqfvlefattkptngstaedprpsspspsltgqp 487
           ******555550.....355555555555566666666666666666666666666666666666666666666666777777777777 PP
   S: 275  ......................................................................................... 274
                                                                                                    
   Q: 488  vgeavcqdsrdtdppealvsscqrtpiykpftqcrppiecpphpaphsiseeelhfvktclqrwraevendinelkanmdrlgqmlesm 576
           77777777777777777777777778888888888888888888888888888888888888888888888889999999999999999 PP
   S: 275  .......kkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtevkeeevleetg.....staYvlfYk 336
                  ++ Y+L+av+vH+G++s GHY+ay++++ ++ W++++D +++e+++ee ++++      ++aY+l+Y 
   Q: 577  ysdnrlcQVPYRLHAVLVHEGQASAGHYWAYIYDHANQrWMKYNDINISESSWEELERDSFggltnASAYCLMYI 651
           9999999***************************88888*******************8779************6 PP

Organism

Tetraodon nigroviridis

Protein Sequence
(Fasta)

RAAELRRFAL NLAPGLCPQS DLLINQLKEI TGIQDPQLLL SALNASQGDV GQAVGLLTSQ 60
PLEVRDPGDP QESKSTDETW RAQKGAKPFL ETFQKMLSSV ILPKDELQTA IELSLQESHN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGGGCGGCTG AACTGAGAAG GTTTGCTCTG AACCTGGCTC CTGGTCTCTG CCCTCAGAGC 60
GACCTGCTGA TCAACCAGCT GAAGGAGATC ACTGGGATCC AGGATCCACA GCTTCTCCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR009060--UBA-like
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0021551--P:central nervous system morphogenesis
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001836	Ailuropoda melanoleuca	54.64	0.00e+00	1118.00
IUUC-Apl-004010	Anas platyrhynchos	51.49	0.00e+00	1063.00
IUUC-Aca-004741	Anolis carolinensis	52.53	0.00e+00	689.00
IUUC-Ang-009577	Aspergillus niger	30.48	1.00e-10	62.40
IUUC-Ate-010275	Aspergillus terreus	33.73	4.00e-11	63.90
IUUC-Bgr-011993	Blumeria graminis	36.49	6.00e-12	67.00
IUUC-Bta-013377	Bos taurus	53.43	0.00e+00	1087.00
IUUC-Cel-018346	Caenorhabditis elegans	27.92	9.00e-29	122.00
IUUC-Cja-019977	Callithrix jacchus	54.53	0.00e+00	1102.00
IUUC-Cfa-020378	Canis familiaris	55.87	0.00e+00	738.00
IUUC-Cpo-021817	Cavia porcellus	53.74	0.00e+00	1090.00
IUUC-Cho-024717	Choloepus hoffmanni	43.68	3.00e-122	432.00
IUUC-Csv-025911	Ciona savignyi	35.15	1.00e-144	506.00
IUUC-Cme-027167	Cyanidioschyzon merolae	27.07	8.00e-20	92.80
IUUC-Dre-028105	Danio rerio	71.02	0.00e+00	960.00
IUUC-Dor-030955	Dipodomys ordii	52.71	0.00e+00	1063.00
IUUC-Ete-032828	Echinops telfairi	50.06	0.00e+00	691.00
IUUC-Eca-034300	Equus caballus	54.05	0.00e+00	1078.00
IUUC-Eeu-034458	Erinaceus europaeus	53.01	0.00e+00	959.00
IUUC-Fca-035753	Felis catus	55.27	0.00e+00	1139.00
IUUC-Fal-037062	Ficedula albicollis	50.95	0.00e+00	640.00
IUUC-Gmo-039593	Gadus morhua	70.32	0.00e+00	1449.00
IUUC-Gac-041867	Gasterosteus aculeatus	77.09	0.00e+00	1658.00
IUUC-Ggo-045384	Gorilla gorilla	53.95	0.00e+00	1104.00
IUUC-Hsa-046277	Homo sapiens	54.00	0.00e+00	1106.00
IUUC-Itr-048276	Ictidomys tridecemlineatus	46.73	1.00e-172	599.00
IUUC-Lch-049692	Latimeria chalumnae	57.70	0.00e+00	1187.00
IUUC-Laf-053808	Loxodonta africana	51.87	0.00e+00	1031.00
IUUC-Meu-056416	Macropus eugenii	46.41	0.00e+00	860.00
IUUC-Mga-060011	Meleagris gallopavo	52.36	0.00e+00	1040.00
IUUC-Mmr-060720	Microcebus murinus	53.19	0.00e+00	1063.00
IUUC-Mdo-061955	Monodelphis domestica	56.72	0.00e+00	739.00
IUUC-Mmu-063870	Mus musculus	55.16	0.00e+00	733.00
IUUC-Mpu-066454	Mustela putorius furo	55.07	0.00e+00	736.00
IUUC-Mlu-067487	Myotis lucifugus	52.31	0.00e+00	1068.00
IUUC-Nle-070044	Nomascus leucogenys	54.04	0.00e+00	1103.00
IUUC-Opr-070888	Ochotona princeps	64.21	5.00e-95	342.00
IUUC-Ont-072386	Oreochromis niloticus	75.71	0.00e+00	1132.00
IUUC-Ocu-074523	Oryctolagus cuniculus	52.85	0.00e+00	1082.00
IUUC-Ola-086393	Oryzias latipes	73.97	0.00e+00	1573.00
IUUC-Oga-088618	Otolemur garnettii	55.18	0.00e+00	1107.00
IUUC-Psi-093422	Pelodiscus sinensis	53.54	0.00e+00	704.00
IUUC-Pma-094250	Petromyzon marinus	45.23	5.00e-67	247.00
IUUC-Pno-095093	Phaeosphaeria nodorum	32.71	5.00e-13	70.10
IUUC-Pfo-096466	Poecilia formosa	76.70	0.00e+00	1141.00
IUUC-Pab-098337	Pongo abelii	53.55	0.00e+00	1100.00
IUUC-Pva-102226	Pteropus vampyrus	52.32	0.00e+00	978.00
IUUC-Sha-107489	Sarcophilus harrisii	55.26	0.00e+00	1119.00
IUUC-Ssl-108532	Sclerotinia sclerotiorum	33.33	1.00e-09	59.30
IUUC-Tgu-116609	Taeniopygia guttata	53.07	0.00e+00	1040.00
IUUC-Tru-117807	Takifugu rubripes	84.76	0.00e+00	1800.00
IUUC-Ttr-128887	Tursiops truncatus	50.56	0.00e+00	996.00
IUUC-Uma-129338	Ustilago maydis	23.47	4.00e-13	70.90
IUUC-Xtr-132436	Xenopus tropicalis	50.51	0.00e+00	1028.00
IUUC-Xma-133995	Xiphophorus maculatus	75.77	0.00e+00	1105.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence