iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Bta-012875

Ensembl Protein ID

ENSBTAP00000007890.3

UniProt Accession

Q2KJA1; Q1JPK1; SH3G1_BOVIN

Genbank Protein ID

ABF57308.1; AAI05445.1

Protein Name

Endophilin-A2; Endophilin-2; SH3 domain protein 2B; SH3 domain-containing GRB2-like protein 1

Genbank Nucleotide ID

BT025352; BC105444

Gene Name

SH3GL1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000006007.3	ENSBTAT00000007890.3	ENSBTAP00000007890.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	3.90e-14	52.5	310	363

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekl 62
            +++lyd+e++nd+eL +++Gd++++   ++ de+W +g   l g++G+fP  +ve l
   Q: 310  SCKALYDFEPENDGELGFHEGDIITLT--NQIDENWYEG--MLDGQSGFFPLSYVEVL 363
           69************************7..99********..8*************976 PP

Organism

Bos taurus

Functional Description
(View)

Implicated in endocytosis. May recruit other proteins to membranes with high curvature (By similarity).

Protein Sequence
(Fasta)

MSVAGLKKQF YKASQLVSEK VGGAEGTKLD DDFKEMEKKV DVTSKAVTEV LARTIEYLQP 60
NPASRAKLTM LNTVSKIRGQ VKNPGYPQSE GLLGECMIRH GKELGGESNF GDALLDAGES 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATATCCTGGC CGCGCGGGCT CGCGAGGGTC TGAGGCGGCG CCGGGGCGGG CGGAGCTGGC 60
TTGAGGGCGG CGAAGGCGGT GCCGTAGGGG CCCCCTGAGG CGCGCTGGGG GTTGGTGGCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0965--Cell junction
KW-0966--Cell projection
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0254--Endocytosis
KW-0967--Endosome
KW-0446--Lipid-binding
KW-0472--Membrane
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR027267--AH/BAR-dom
IPR004148--BAR_dom
IPR001452--SH3_domain

PROSITE

PS51021--BAR
PS50002--SH3

Pfam

PF03114--BAR
PF00018--SH3_1

PRINTS

PR00452--SH3DOMAIN

SMART

SM00721--BAR
SM00326--SH3

Gene Ontology

GO:0030054--C:cell junction
GO:0042995--C:cell projection
GO:0031901--C:early endosome membrane
GO:0002102--C:podosome
GO:0045202--C:synapse
GO:0008289--F:lipid binding
GO:0016191--P:synaptic vesicle uncoating

KEGG

bta:512719

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001620	Ailuropoda melanoleuca	95.28	0.00e+00	672.00
IUUC-Apl-004209	Anas platyrhynchos	90.17	1.00e-174	605.00
IUUC-Ame-011047	Astyanax mexicanus	74.80	5.00e-155	540.00
IUUC-Cel-018509	Caenorhabditis elegans	44.76	4.00e-93	334.00
IUUC-Cin-025799	Ciona intestinalis	50.68	2.00e-103	369.00
IUUC-Csv-026266	Ciona savignyi	51.50	4.00e-101	361.00
IUUC-Cne-027089	Cryptococcus neoformans	25.82	1.00e-07	51.60
IUUC-Dre-027986	Danio rerio	75.34	2.00e-158	551.00
IUUC-Dno-029193	Dasypus novemcinctus	95.65	0.00e+00	694.00
IUUC-Dor-030288	Dipodomys ordii	85.33	3.00e-174	603.00
IUUC-Eca-033277	Equus caballus	95.48	0.00e+00	652.00
IUUC-Fal-036965	Ficedula albicollis	90.27	0.00e+00	633.00
IUUC-Gmo-039523	Gadus morhua	73.30	1.00e-152	532.00
IUUC-Gga-040426	Gallus gallus	91.30	0.00e+00	641.00
IUUC-Gac-042642	Gasterosteus aculeatus	75.41	1.00e-159	555.00
IUUC-Ggo-045448	Gorilla gorilla	97.01	0.00e+00	706.00
IUUC-Hsa-046112	Homo sapiens	97.01	0.00e+00	708.00
IUUC-Itr-048752	Ictidomys tridecemlineatus	95.65	0.00e+00	696.00
IUUC-Lch-050556	Latimeria chalumnae	60.15	2.00e-134	472.00
IUUC-Loc-052447	Lepisosteus oculatus	78.55	1.00e-169	588.00
IUUC-Laf-053698	Loxodonta africana	96.47	0.00e+00	729.00
IUUC-Mcc-055547	Macaca mulatta	91.30	0.00e+00	632.00
IUUC-Meu-056398	Macropus eugenii	81.25	2.00e-172	597.00
IUUC-Mga-060168	Meleagris gallopavo	88.48	4.00e-174	603.00
IUUC-Mmr-061056	Microcebus murinus	95.92	0.00e+00	699.00
IUUC-Mmu-063596	Mus musculus	93.75	0.00e+00	683.00
IUUC-Mpu-066681	Mustela putorius furo	96.47	0.00e+00	702.00
IUUC-Mlu-068113	Myotis lucifugus	91.01	0.00e+00	652.00
IUUC-Nle-070104	Nomascus leucogenys	94.89	4.00e-180	623.00
IUUC-Opr-070661	Ochotona princeps	95.95	0.00e+00	692.00
IUUC-Ont-071922	Oreochromis niloticus	75.54	8.00e-159	552.00
IUUC-Ola-086645	Oryzias latipes	77.57	2.00e-173	601.00
IUUC-Oga-088627	Otolemur garnettii	95.76	0.00e+00	701.00
IUUC-Pan-092433	Papio anubis	95.25	0.00e+00	658.00
IUUC-Psi-092940	Pelodiscus sinensis	90.25	0.00e+00	661.00
IUUC-Pma-094657	Petromyzon marinus	63.26	7.00e-122	429.00
IUUC-Pfo-096876	Poecilia formosa	76.09	2.00e-160	558.00
IUUC-Pab-097667	Pongo abelii	82.72	7.00e-158	549.00
IUUC-Pca-100102	Procavia capensis	88.59	0.00e+00	662.00
IUUC-Pva-102731	Pteropus vampyrus	86.68	3.00e-177	613.00
IUUC-Pgr-103312	Puccinia graminis	24.79	2.00e-15	77.80
IUUC-Ptt-103801	Puccinia triticina	22.78	6.00e-13	69.30
IUUC-Rno-105425	Rattus norvegicus	92.93	0.00e+00	681.00
IUUC-Sha-106675	Sarcophilus harrisii	93.11	0.00e+00	689.00
IUUC-Ssc-115548	Sus scrofa	97.29	0.00e+00	684.00
IUUC-Tru-117979	Takifugu rubripes	77.03	3.00e-162	564.00
IUUC-Tni-120585	Tetraodon nigroviridis	76.36	1.00e-161	562.00
IUUC-Ttr-128449	Tursiops truncatus	97.18	0.00e+00	654.00
IUUC-Xtr-131935	Xenopus tropicalis	82.34	1.00e-166	578.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence