iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
IID
Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	31.53	3.00e-37	154.00	IUUC-Hsa-046869

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Drosophila melanogaster

Protein Sequence
(Fasta)

MWCIVNLPNG TQQAVKWDPK ANGQECLEKV CRAMNIICEM EYFGLEHWTP NQKESQTRQW 60
INLRNRLSGD SGSSGSGIQL MLALRVKFWV PVHFILQESV RNLFYMQARR DLLEGRLTAP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATTCTATGTT TGGCAGCTCT GTGTTAAACA CCGAATACTC TGAAACAAAA ACAACAAGGA 60
TATCCGTGAA ATCGCCGGGA AAAAAATATA TCACGAAGTA ATATTTTTAT TTTTGCACAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR019749--Band_41_domain
IPR014352--FERM/acyl-CoA-bd_prot_3-hlx
IPR019748--FERM_central
IPR000299--FERM_domain
IPR018979--FERM_N
IPR018980--FERM_PH-like_C
IPR011993--PH_dom-like
IPR029071--Ubiquitin-rel_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50057--FERM_3
PS50089--ZF_RING_2

Pfam

PF00373--FERM_M
PF09379--FERM_N

SMART

SM00295--B41
SM01196--FERM_C

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0007476--P:imaginal disc-derived wing morphogenesis
GO:0002814--P:negative regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria
GO:0016567--P:protein ubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0030431--P:sleep

KEGG

dme:Dmel_CG12489

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001425	Ailuropoda melanoleuca	31.38	2.00e-39	155.00
IUUC-Apl-003704	Anas platyrhynchos	32.35	4.00e-37	148.00
IUUC-Aca-004645	Anolis carolinensis	31.91	3.00e-35	142.00
IUUC-Ame-011401	Astyanax mexicanus	30.86	7.00e-32	130.00
IUUC-Bta-012752	Bos taurus	30.15	1.00e-35	143.00
IUUC-Cja-019734	Callithrix jacchus	30.15	7.00e-37	147.00
IUUC-Cfa-020145	Canis familiaris	31.69	2.00e-39	155.00
IUUC-Cpo-021436	Cavia porcellus	30.46	8.00e-38	150.00
IUUC-Csa-024248	Chlorocebus sabaeus	30.15	4.00e-37	147.00
IUUC-Cho-024528	Choloepus hoffmanni	36.32	1.00e-27	116.00
IUUC-Cin-025748	Ciona intestinalis	35.29	2.00e-18	85.50
IUUC-Csv-025837	Ciona savignyi	30.83	2.00e-30	125.00
IUUC-Dre-027847	Danio rerio	32.31	5.00e-35	141.00
IUUC-Dno-029860	Dasypus novemcinctus	32.00	3.00e-33	135.00
IUUC-Dor-030664	Dipodomys ordii	36.46	2.00e-21	95.90
IUUC-Ete-032496	Echinops telfairi	37.13	1.00e-21	96.70
IUUC-Eca-033674	Equus caballus	31.31	3.00e-38	151.00
IUUC-Eeu-035048	Erinaceus europaeus	27.22	3.00e-27	115.00
IUUC-Fca-036547	Felis catus	32.31	2.00e-40	159.00
IUUC-Fal-037504	Ficedula albicollis	31.97	4.00e-37	148.00
IUUC-Gmo-038660	Gadus morhua	36.54	3.00e-27	115.00
IUUC-Gga-040123	Gallus gallus	31.69	9.00e-39	153.00
IUUC-Gac-042073	Gasterosteus aculeatus	33.02	2.00e-32	132.00
IUUC-Ggo-045387	Gorilla gorilla	29.85	7.00e-37	147.00
IUUC-Hsa-046869	Homo sapiens	30.15	9.00e-38	150.00
IUUC-Itr-047917	Ictidomys tridecemlineatus	31.08	2.00e-37	149.00
IUUC-Lch-049990	Latimeria chalumnae	32.00	4.00e-37	148.00
IUUC-Loc-051908	Lepisosteus oculatus	32.62	1.00e-34	139.00
IUUC-Laf-053915	Loxodonta africana	31.08	9.00e-38	150.00
IUUC-Mcc-054865	Macaca mulatta	30.15	5.00e-37	147.00
IUUC-Meu-056826	Macropus eugenii	55.56	1.00e-17	83.60
IUUC-Mga-059827	Meleagris gallopavo	31.94	1.00e-37	149.00
IUUC-Mmr-060734	Microcebus murinus	32.31	3.00e-40	158.00
IUUC-Mdo-062988	Monodelphis domestica	33.23	2.00e-42	165.00
IUUC-Mmu-064415	Mus musculus	35.58	6.00e-29	120.00
IUUC-Mpu-066118	Mustela putorius furo	31.38	1.00e-37	149.00
IUUC-Mlu-067131	Myotis lucifugus	31.69	1.00e-35	143.00
IUUC-Nle-070112	Nomascus leucogenys	30.46	3.00e-37	148.00
IUUC-Opr-071193	Ochotona princeps	30.15	7.00e-37	147.00
IUUC-Ont-072635	Oreochromis niloticus	31.79	3.00e-33	135.00
IUUC-Oan-073266	Ornithorhynchus anatinus	32.00	2.00e-38	152.00
IUUC-Ocu-074903	Oryctolagus cuniculus	32.31	1.00e-40	159.00
IUUC-Olo-080263	Oryza longistaminata	40.35	1.00e-04	41.60
IUUC-Ola-087533	Oryzias latipes	29.23	5.00e-31	128.00
IUUC-Oga-087979	Otolemur garnettii	31.69	1.00e-39	156.00
IUUC-Oar-089747	Ovis aries	29.85	7.00e-35	140.00
IUUC-Ptr-090732	Pan troglodytes	30.15	2.00e-37	149.00
IUUC-Pan-092032	Papio anubis	30.15	4.00e-37	147.00
IUUC-Psi-093296	Pelodiscus sinensis	33.01	8.00e-40	157.00
IUUC-Pma-094351	Petromyzon marinus	29.68	4.00e-14	70.10
IUUC-Pfo-097183	Poecilia formosa	32.31	2.00e-28	119.00
IUUC-Pab-098177	Pongo abelii	29.85	1.00e-36	146.00
IUUC-Pca-100734	Procavia capensis	30.77	2.00e-35	142.00
IUUC-Pva-102778	Pteropus vampyrus	31.15	2.00e-33	135.00
IUUC-Rno-106039	Rattus norvegicus	30.77	4.00e-38	151.00
IUUC-Sha-106869	Sarcophilus harrisii	33.23	7.00e-43	167.00
IUUC-Sly-110945	Solanum lycopersicum	43.14	5.00e-09	55.10
IUUC-Sar-113587	Sorex araneus	36.78	7.00e-25	107.00
IUUC-Ssc-116212	Sus scrofa	30.15	5.00e-36	144.00
IUUC-Tgu-116871	Taeniopygia guttata	32.31	2.00e-37	149.00
IUUC-Tru-117925	Takifugu rubripes	33.54	7.00e-36	144.00
IUUC-Tsy-118815	Tarsius syrichta	32.00	4.00e-40	157.00
IUUC-Tni-120007	Tetraodon nigroviridis	32.72	3.00e-30	125.00
IUUC-Tbe-127381	Tupaia belangeri	31.61	2.00e-37	149.00
IUUC-Ttr-129025	Tursiops truncatus	33.47	4.00e-31	128.00
IUUC-Vpa-130164	Vicugna pacos	29.55	3.00e-32	132.00
IUUC-Xtr-132800	Xenopus tropicalis	31.17	2.00e-33	135.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence