iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oga-088005

Ensembl Protein ID

ENSOGAP00000014298.1

UniProt Accession

H0XED1; H0XED1_OTOGA

Genbank Protein ID

ENSOGAP00000014298

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03186919

Gene Name

UBQLN2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000015969.1	ENSOGAT00000015972.1	ENSOGAP00000014298.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBA	1.70e-10	40.7	582	619
ULD/UDP/UBQ/UBQ_PIM	2.00e-23	82.2	33	106

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBA

   S: 3    dedkleqlveMGF.dreealqaLraannnleaAveyLl 39
           ++++leql +MGF +re++lqaL a++++++aA+e+Ll
   Q: 582  FQQQLEQLNAMGFlNREANLQALIATGGDINAAIERLL 619
           799**********************************9 PP

ULD/UDP/UBQ/UBQ_PIM

   S: 1    mkltvktlkgkefelevseddtveelKekiakesgvppeqqkLIyaGkiLkDdttLselgikdgsvvhlvvkksk 75
           +k+tvkt+k+ke e+ v e+++v+++Ke+i+k+++ + +q+ LI+aGkiLkD++tL ++gi+dg +vhlv+k ++
   Q: 33   IKVTVKTPKEKE-EFAVPENSSVQQFKEAISKRFKSQTDQLVLIFAGKILKDQDTLIQHGIHDGLTVHLVIKSQN 106
           69**********.***********************************************************986 PP

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

MAENGESSGP PRPSPGPAAA QGSAAAAAEP KIIKVTVKTP KEKEEFAVPE NSSVQQFKEA 60
ISKRFKSQTD QLVLIFAGKI LKDQDTLIQH GIHDGLTVHL VIKSQNRPQS QSTQPSNAAG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTGAGA ACGGAGAGAG CAGCGGCCCC CCGCGCCCCT CCCCCGGCCC TGCTGCGGCC 60
CAAGGCTCAG CAGCCGCCGC AGCTGAGCCC AAAATCATCA AAGTCACTGT GAAGACCCCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR016024--ARM-type_fold
IPR006636--STI1_HS-bd
IPR015940--UBA
IPR009060--UBA-like
IPR015496--Ubiquilin
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom

PROSITE

PS50030--UBA
PS50053--UBIQUITIN_2

Pfam

PF00627--UBA
PF00240--ubiquitin

SMART

SM00727--STI1
SM00165--UBA
SM00213--UBQ

Gene Ontology

GO:0005829--C:cytosol
GO:0005886--C:plasma membrane
GO:1900186--P:negative regulation of clathrin-dependent endocytosis
GO:1904021--P:negative regulation of G-protein coupled receptor internalization
GO:1903071--P:positive regulation of ER-associated ubiquitin-dependent protein catabolic process
GO:2000785--P:regulation of autophagosome assembly
GO:0030433--P:ubiquitin-dependent ERAD pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Bta-013571	Bos taurus	96.90	0.00e+00	741.00
IUUC-Cfa-020799	Canis familiaris	97.07	0.00e+00	633.00
IUUC-Cpo-022093	Cavia porcellus	96.77	2.00e-173	602.00
IUUC-Cre-022634	Chlamydomonas reinhardtii	48.15	3.00e-11	62.80
IUUC-Csa-023627	Chlorocebus sabaeus	98.10	0.00e+00	753.00
IUUC-Cho-024552	Choloepus hoffmanni	92.36	3.00e-173	601.00
IUUC-Csv-026009	Ciona savignyi	46.12	2.00e-101	362.00
IUUC-Cne-026833	Cryptococcus neoformans	27.04	9.00e-13	67.80
IUUC-Dno-029647	Dasypus novemcinctus	94.82	1.00e-174	606.00
IUUC-Ete-033071	Echinops telfairi	91.60	0.00e+00	741.00
IUUC-Eeu-034727	Erinaceus europaeus	93.46	0.00e+00	716.00
IUUC-Fca-035803	Felis catus	97.52	7.00e-179	620.00
IUUC-Fso-038204	Fusarium solani	42.25	1.00e-08	53.90
IUUC-Hsa-046768	Homo sapiens	98.87	8.00e-178	617.00
IUUC-Hvu-047094	Hordeum vulgare	50.98	5.00e-09	53.10
IUUC-Itr-048556	Ictidomys tridecemlineatus	91.70	7.00e-173	600.00
IUUC-Lma-053152	Leptosphaeria maculans	31.82	1.00e-10	61.20
IUUC-Mor-057194	Magnaporthe oryzae	48.00	2.00e-07	50.10
IUUC-Mmr-061605	Microcebus murinus	96.84	5.00e-171	594.00
IUUC-Mac-065526	Musa acuminata	38.46	5.00e-39	155.00
IUUC-Mpu-066474	Mustela putorius furo	97.07	8.00e-179	620.00
IUUC-Mlu-067252	Myotis lucifugus	86.74	7.00e-164	570.00
IUUC-Ncr-068732	Neurospora crassa	48.98	2.00e-07	50.40
IUUC-Nle-069038	Nomascus leucogenys	98.28	0.00e+00	751.00
IUUC-Ocu-074520	Oryctolagus cuniculus	91.92	4.00e-169	587.00
IUUC-Oar-089878	Ovis aries	96.55	0.00e+00	752.00
IUUC-Ptr-090781	Pan troglodytes	98.87	2.00e-178	619.00
IUUC-Pan-091716	Papio anubis	91.55	0.00e+00	691.00
IUUC-Pab-097891	Pongo abelii	98.65	3.00e-178	618.00
IUUC-Pca-100227	Procavia capensis	96.62	1.00e-95	343.00
IUUC-Pgr-103261	Puccinia graminis	54.76	2.00e-07	50.10
IUUC-Sce-106332	Saccharomyces cerevisiae	33.64	9.00e-16	77.80
IUUC-Spo-108223	Schizosaccharomyces pombe	27.48	2.00e-10	59.70
IUUC-Sre-115081	Sporisorium reilianum	26.52	2.00e-11	63.50
IUUC-Tsy-119008	Tarsius syrichta	95.37	1.00e-171	596.00
IUUC-Uma-129639	Ustilago maydis	27.16	4.00e-11	62.40
IUUC-Vda-129991	Verticillium dahliae	46.15	6.00e-07	48.50

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence