iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Hvu-047697

Ensembl Protein ID

MLOC_54346.5

UniProt Accession

M0WSS9; M0WSS9_HORVV

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
MLOC_54346	MLOC_54346.4	MLOC_54346.4
MLOC_54346	MLOC_54346.2	MLOC_54346.2
MLOC_54346	MLOC_54346.5	MLOC_54346.5
MLOC_54346	MLOC_54346.1	MLOC_54346.1
MLOC_54346	MLOC_54346.6	MLOC_54346.6

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	3.80e-121	405.6	3292	3631
UBD/Alpha-Helix/UBA	1.30e-06	29.3	1293	1332

Active Site

Position(s)	Description	Evidence
3599	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlplsksf 96
           ++dlk rl v+f+gEeg+d+gG+tre+++lls+ ++++ + lf ++ +++ t+qpnp+s ++ +ehl++F+f+Gr++gkal+d +lld+++++sf
   Q: 3292 PQDLKGRLTVHFQGEEGIDAGGLTREWYQLLSRVIFDKGALLF-TTVGNDLTFQPNPNSVYQ-TEHLSYFKFVGRVVGKALFDAQLLDVHFTRSF 3384
           689************************************9999.556678899******986.5******************************* PP
   S: 97   yklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseei.....lgetkeee..LkpgGenipVtneNkeeYvklvveyrlke 184
           yk++lg k++++d+e++dp +y++lk+++en   di++  ldltfs++ ++     ++++++++  L+pgG+ni+Vt+eNk+eYv++v+e+rl++
   Q: 3385 YKHILGAKVTYHDIEAIDPAYYRNLKWMLEN---DISDV-LDLTFSMDADEeklilYEKAEVTDceLIPGGRNIRVTEENKHEYVDRVAEHRLTT 3475
           *****************************99...99998.99999977776779996555555455***************************** PP
   S: 185  gikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFvTgssrlPlgGf 279
            i+ q++af eGfne+ip el+s+F+ +e+elli+G ++id++dlk++t+y +gy+  sp+iqwFwe++++fs+e++++fLqFvTg+s++Pl+Gf
   Q: 3476 AIRPQINAFMEGFNELIPRELISIFNDKEFELLISGLPDIDLDDLKANTEY-SGYSIASPVIQWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGF 3569
           ***************************************************.55***************************************** PP
   S: 280  aelk....prlfvirk.dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieet.kgFel 335
            +l+    p++f+i+k ++s+++lPs++TCfn+L+LPeY+sk++l+e+Ll+Ai+e+ +gF++
   Q: 3570 SALQgisgPQRFQIHKaYGSTNHLPSAHTCFNQLDLPEYTSKDQLQERLLLAIHEAnEGFGF 3631
           ****************99999***********************************9***85 PP

UBD/Alpha-Helix/UBA

   S: 3    dedkleqlveMGFdreealqaLraa.nnnleaAveyLldg 41
           de ++  ++eMGF+r +a +aLr+   n++e A+++L+++
   Q: 1293 DENAISLIIEMGFSRARAEEALRQVgTNSVEIATDWLFSH 1332
           678899999*****************************97 PP

Organism

Hordeum vulgare

Protein Sequence
(Fasta)

MAAAAMAAHR ASFPLRLQQI LSGSRAVSPA IKVESEPPAK VKAFIDRVIN IPLHDIAIPL 60
SGFHWEFNKG NFHHWKPLFM HFDTYFKTYI SSRKDLLLSD DMSEGEPLTK NTILQILRVM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CACAAAAGCA CCGCTTCCCC AGGTTTTCTC CCTTCTCTTC ATCATACCCA AACACCTCAA 60
CTCCTCTTCT CTTCCTCTCT CCTCCCTTAG CCATCTCCGA ATCCCGCCTA GCCGCCTCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR025527--DUF4414
IPR010309--E3_Ub_ligase_DUF908
IPR010314--E3_Ub_ligase_DUF913
IPR000569--HECT_dom
IPR015940--UBA
IPR009060--UBA-like

PROSITE

PS50237--HECT
PS50030--UBA

Pfam

PF14377--DUF4414
PF06012--DUF908
PF06025--DUF913
PF00632--HECT
PF00627--UBA

SMART

SM00119--HECTc
SM00165--UBA

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000627	Aegilops tauschii	95.05	0.00e+00	6241.00
IUUC-Aml-001684	Ailuropoda melanoleuca	51.38	9.00e-128	452.00
IUUC-Atr-002582	Amborella trichopoda	59.84	0.00e+00	2212.00
IUUC-Apl-003400	Anas platyrhynchos	42.53	2.00e-96	345.00
IUUC-Aca-005263	Anolis carolinensis	51.38	2.00e-128	454.00
IUUC-Aly-006157	Arabidopsis lyrata	56.20	0.00e+00	2176.00
IUUC-Ath-007160	Arabidopsis thaliana	57.19	0.00e+00	1082.00
IUUC-Ago-008005	Ashbya gossypii	42.48	4.00e-126	446.00
IUUC-Acl-008254	Aspergillus clavatus	41.38	1.00e-135	478.00
IUUC-Afl-008712	Aspergillus flavus	39.35	2.00e-138	486.00
IUUC-Afu-009022	Aspergillus fumigatus	40.91	4.00e-135	476.00
IUUC-Ani-009412	Aspergillus nidulans	33.33	1.00e-156	548.00
IUUC-Ang-009771	Aspergillus niger	40.03	2.00e-137	484.00
IUUC-Aor-010186	Aspergillus oryzae	38.63	4.00e-129	454.00
IUUC-Ate-010253	Aspergillus terreus	33.25	9.00e-155	541.00
IUUC-Ame-011067	Astyanax mexicanus	51.75	2.00e-126	447.00
IUUC-Bgr-012043	Blumeria graminis	41.51	1.00e-133	471.00
IUUC-Bta-012813	Bos taurus	51.38	1.00e-127	452.00
IUUC-Bci-013995	Botrytis cinerea	42.02	2.00e-136	481.00
IUUC-Bdi-014884	Brachypodium distachyon	91.00	0.00e+00	6064.00
IUUC-Bol-015228	Brassica oleracea	55.15	0.00e+00	1890.00
IUUC-Bra-016726	Brassica rapa	54.81	0.00e+00	1975.00
IUUC-Cel-018179	Caenorhabditis elegans	47.26	9.00e-122	432.00
IUUC-Cja-018741	Callithrix jacchus	51.49	5.00e-127	449.00
IUUC-Cfa-020083	Canis familiaris	51.38	1.00e-127	452.00
IUUC-Cpo-021766	Cavia porcellus	42.99	5.00e-98	351.00
IUUC-Cre-022900	Chlamydomonas reinhardtii	60.09	6.00e-157	545.00
IUUC-Csa-023853	Chlorocebus sabaeus	51.38	1.00e-127	452.00
IUUC-Cho-024718	Choloepus hoffmanni	53.66	4.00e-117	416.00
IUUC-Cin-025627	Ciona intestinalis	50.12	4.00e-123	436.00
IUUC-Csv-025872	Ciona savignyi	49.77	2.00e-119	421.00
IUUC-Cgl-026647	Colletotrichum gloeosporioides	32.12	5.00e-144	506.00
IUUC-Cme-027267	Cyanidioschyzon merolae	53.05	1.00e-126	447.00
IUUC-Dre-028525	Danio rerio	50.89	2.00e-113	404.00
IUUC-Dno-029680	Dasypus novemcinctus	51.38	1.00e-127	451.00
IUUC-Dor-030902	Dipodomys ordii	45.87	5.00e-108	386.00
IUUC-Dse-031197	Dothistroma septosporum	39.53	5.00e-132	466.00
IUUC-Dme-032122	Drosophila melanogaster	48.63	3.00e-121	431.00
IUUC-Ete-032966	Echinops telfairi	42.76	4.00e-98	351.00
IUUC-Eca-033915	Equus caballus	50.80	2.00e-125	444.00
IUUC-Eeu-034963	Erinaceus europaeus	51.03	1.00e-125	445.00
IUUC-Fca-035824	Felis catus	51.38	9.00e-128	452.00
IUUC-Fal-036687	Ficedula albicollis	42.76	2.00e-97	348.00
IUUC-Fox-037756	Fusarium oxysporum	33.00	1.00e-154	541.00
IUUC-Fso-038464	Fusarium solani	32.13	8.00e-151	528.00
IUUC-Gmo-039073	Gadus morhua	51.99	7.00e-128	452.00
IUUC-Ggr-039946	Gaeumannomyces graminis	41.12	9.00e-132	465.00
IUUC-Gga-040845	Gallus gallus	42.53	6.00e-97	347.00
IUUC-Gac-042430	Gasterosteus aculeatus	51.99	6.00e-128	452.00
IUUC-Gma-043129	Glycine max	57.51	0.00e+00	2306.00
IUUC-Ggo-044465	Gorilla gorilla	42.66	3.00e-96	345.00
IUUC-Hsa-046879	Homo sapiens	51.38	1.00e-127	452.00
IUUC-Itr-048430	Ictidomys tridecemlineatus	51.38	6.00e-128	451.00
IUUC-Kpa-049228	Komagataella pastoris	40.50	3.00e-126	446.00
IUUC-Lch-050252	Latimeria chalumnae	51.49	5.00e-127	449.00
IUUC-Lpe-051550	Leersia perrieri	85.57	0.00e+00	5575.00
IUUC-Loc-052472	Lepisosteus oculatus	51.99	1.00e-127	452.00
IUUC-Lma-053159	Leptosphaeria maculans	32.49	2.00e-145	510.00
IUUC-Laf-054154	Loxodonta africana	51.38	8.00e-128	452.00
IUUC-Mcc-055085	Macaca mulatta	51.38	9.00e-128	452.00
IUUC-Meu-056751	Macropus eugenii	44.85	8.00e-78	284.00
IUUC-Mor-057201	Magnaporthe oryzae	32.50	8.00e-144	505.00
IUUC-Mpo-057597	Magnaporthe poae	41.43	2.00e-132	467.00
IUUC-Mtr-057633	Medicago truncatula	57.58	0.00e+00	2254.00
IUUC-Mla-058888	Melampsora laricipopulina	46.59	2.00e-113	401.00
IUUC-Mga-059935	Meleagris gallopavo	42.53	5.00e-97	347.00
IUUC-Mvi-060320	Microbotryum violaceum	46.15	3.00e-121	430.00
IUUC-Mmr-060820	Microcebus murinus	51.38	8.00e-128	452.00
IUUC-Mdo-062930	Monodelphis domestica	51.38	4.00e-128	453.00
IUUC-Mmu-063601	Mus musculus	51.38	7.00e-128	452.00
IUUC-Mac-065499	Musa acuminata	67.44	0.00e+00	4359.00
IUUC-Mpu-066653	Mustela putorius furo	51.38	1.00e-127	452.00
IUUC-Mlu-067418	Myotis lucifugus	51.38	7.00e-128	452.00
IUUC-Nfi-068278	Neosartorya fischeri	41.22	6.00e-136	479.00
IUUC-Ncr-068813	Neurospora crassa	40.18	1.00e-140	495.00
IUUC-Nle-069418	Nomascus leucogenys	51.38	1.00e-127	451.00
IUUC-Opr-070585	Ochotona princeps	45.08	6.00e-93	334.00
IUUC-Ont-071300	Oreochromis niloticus	51.99	1.00e-127	452.00
IUUC-Oan-073046	Ornithorhynchus anatinus	51.14	1.00e-126	448.00
IUUC-Ocu-074178	Oryctolagus cuniculus	51.38	5.00e-128	452.00
IUUC-Oba-075757	Oryza barthii	86.66	0.00e+00	5629.00
IUUC-Obr-076553	Oryza brachyantha	86.86	0.00e+00	5730.00
IUUC-Ogl-077520	Oryza glaberrima	86.94	0.00e+00	5774.00
IUUC-Ogu-078278	Oryza glumaepatula	85.59	0.00e+00	5690.00
IUUC-Oin-079767	Oryza indica	86.64	0.00e+00	5748.00
IUUC-Olo-080380	Oryza longistaminata	85.00	0.00e+00	5669.00
IUUC-Ome-081925	Oryza meridionalis	86.82	0.00e+00	5757.00
IUUC-Oni-082619	Oryza nivara	86.86	0.00e+00	5761.00
IUUC-Opu-083684	Oryza punctata	84.76	0.00e+00	5650.00
IUUC-Oru-084501	Oryza rufipogon	87.03	0.00e+00	5779.00
IUUC-Osa-086251	Oryza sativa	90.48	0.00e+00	1415.00
IUUC-Ola-086777	Oryzias latipes	43.28	8.00e-99	353.00
IUUC-Olu-087813	Ostreococcus lucimarinus	50.85	3.00e-123	433.00
IUUC-Oga-088903	Otolemur garnettii	51.38	9.00e-128	452.00
IUUC-Oar-090210	Ovis aries	51.38	9.00e-128	452.00
IUUC-Ptr-090529	Pan troglodytes	42.76	8.00e-98	350.00
IUUC-Pan-092368	Papio anubis	50.50	3.00e-114	407.00
IUUC-Psi-093969	Pelodiscus sinensis	42.53	3.00e-97	348.00
IUUC-Pma-094364	Petromyzon marinus	46.19	1.00e-88	318.00
IUUC-Pno-094871	Phaeosphaeria nodorum	37.99	3.00e-132	467.00
IUUC-Ppa-095657	Physcomitrella patens	38.13	0.00e+00	1191.00
IUUC-Pfo-096232	Poecilia formosa	51.99	7.00e-128	452.00
IUUC-Pab-098583	Pongo abelii	51.38	9.00e-128	452.00
IUUC-Pop-099468	Populus trichocarpa	61.44	0.00e+00	4014.00
IUUC-Pca-100596	Procavia capensis	43.29	2.00e-86	312.00
IUUC-Ppe-101641	Prunus persica	58.97	0.00e+00	2203.00
IUUC-Pva-102116	Pteropus vampyrus	47.59	1.00e-113	405.00
IUUC-Pgr-103465	Puccinia graminis	42.94	5.00e-123	436.00
IUUC-Ptt-103813	Puccinia triticina	40.78	4.00e-113	403.00
IUUC-Pte-104018	Pyrenophora teres	37.99	2.00e-131	464.00
IUUC-Pyt-104713	Pyrenophora triticirepentis	31.77	7.00e-143	502.00
IUUC-Rno-105153	Rattus norvegicus	42.76	4.00e-98	351.00
IUUC-Sce-106449	Saccharomyces cerevisiae	40.69	9.00e-121	428.00
IUUC-Sha-106961	Sarcophilus harrisii	44.14	3.00e-128	453.00
IUUC-Sja-107814	Schizosaccharomyces japonicus	31.83	1.00e-131	464.00
IUUC-Spo-108024	Schizosaccharomyces pombe	32.28	7.00e-135	475.00
IUUC-Ssl-108514	Sclerotinia sclerotiorum	45.16	5.00e-96	344.00
IUUC-Smo-109428	Selaginella moellendorffii	54.95	0.00e+00	1095.00
IUUC-Sit-110598	Setaria italica	85.57	0.00e+00	3313.00
IUUC-Sly-111706	Solanum lycopersicum	56.92	0.00e+00	2192.00
IUUC-Stu-112501	Solanum tuberosum	54.95	8.00e-100	355.00
IUUC-Sar-113291	Sorex araneus	51.90	3.00e-123	437.00
IUUC-Sbi-114042	Sorghum bicolor	82.86	0.00e+00	5461.00
IUUC-Sre-114958	Sporisorium reilianum	54.82	1.00e-139	488.00
IUUC-Ssc-115754	Sus scrofa	51.38	1.00e-127	452.00
IUUC-Tgu-117225	Taeniopygia guttata	42.53	5.00e-97	347.00
IUUC-Tru-118570	Takifugu rubripes	52.22	2.00e-128	454.00
IUUC-Tsy-119407	Tarsius syrichta	46.77	9.00e-93	333.00
IUUC-Tni-120836	Tetraodon nigroviridis	51.52	2.00e-124	441.00
IUUC-Tca-121479	Theobroma cacao	60.25	0.00e+00	2347.00
IUUC-Tre-121909	Trichoderma reesei	32.99	4.00e-150	526.00
IUUC-Tvi-122370	Trichoderma virens	32.17	2.00e-144	507.00
IUUC-Tae-125214	Triticum aestivum	94.54	0.00e+00	3358.00
IUUC-Tme-127172	Tuber melanosporum	38.45	4.00e-131	462.00
IUUC-Tbe-127762	Tupaia belangeri	42.01	2.00e-83	303.00
IUUC-Ttr-129253	Tursiops truncatus	51.38	1.00e-127	451.00
IUUC-Uma-129355	Ustilago maydis	47.24	5.00e-141	493.00
IUUC-Vda-129886	Verticillium dahliae	37.86	1.00e-131	464.00
IUUC-Vpa-130708	Vicugna pacos	51.38	2.00e-127	451.00
IUUC-Vvi-131078	Vitis vinifera	59.65	0.00e+00	2049.00
IUUC-Xtr-132123	Xenopus tropicalis	48.64	4.00e-115	410.00
IUUC-Xma-133869	Xiphophorus maculatus	51.99	3.00e-128	453.00
IUUC-Yli-134657	Yarrowia lipolytica	45.77	2.00e-134	473.00
IUUC-Zma-135570	Zea mays	82.23	0.00e+00	5442.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence