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Tag Content
UUCD2 ID IUUC-Tgu-116789
UUCD1 version UUC-TaG-00554
Ensembl Protein ID ENSTGUP00000010823.1
UniProt Accession H0ZJQ4; H0ZJQ4_TAEGU
Genbank Protein ID ENSTGUP00000010823
Protein Name Uncharacterized protein
Genbank Nucleotide ID ABQF01013058
Gene Name HERC2
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSTGUG00000010457.1 ENSTGUT00000010936.1 ENSTGUP00000010823.1
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/HECT 2.40e-86 290.0 4471 4800
Active Site
Position(s) Description Evidence
4769 Glycyl thioester intermediate {ECO:0000256|PROSITE-ProRule:PRU00104}
Domain Profile

   E3 activity/HECT
   S: 7    krlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknp.....ehlklFeflGrllgkalqdgrll 88
           ++++v+fvgE++ d+gG  +e +a++++elqn  ++l+  ++n++ +   n+d +l np      h+++F+flG+llg+a+++g +l
   Q: 4471 RVWKVKFVGESVDDCGGGYSESIAEMCEELQNGLTPLLIVTPNGRDESGANRDCFLLNPaakslLHMNMFRFLGVLLGIAIRTGSPL 4557
           4566*********************************************************************************** PP
   S: 89   dlplsksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvk 175
            l+l+++++k+l g +l++ dl+evd++++  l++i++n+ ++ e +++ l f+     +++++ +++  +++ +++t +N+ eYv+
   Q: 4558 SLNLAEPVWKQLAGMNLTIADLSEVDKDFIPGLMYIRDNEATSEEFEAMSLPFT-----VPNASGQDIQLSSKYTHITLDNRAEYVR 4639
           ***************************************99999999999*999.....788999999******************* PP
   S: 176  lvveyrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerk 262
           l ++yrl+e ++eqv+a+reG+ +v+p  llslFt  ele+++cG+++i ++ lk+ ++ykg ++++ + iqwFwev+e+fs++er+
   Q: 4640 LAINYRLHE-FDEQVAAVREGMARVVPVPLLSLFTGYELETMVCGSPDIPLHLLKSVATYKG-IEPTASLIQWFWEVMESFSNTERS 4724
           *********.**************************************************77.************************ PP
   S: 263  afLqFvTgssrlPlgGfaelkprlfvirk....dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFel 335
            fL+Fv+g+ rlP + +a+++ r fvi+     +  d+ lP+s TCf++LkLP+Ys k++l+ekL yAi+ +k++++
   Q: 4725 LFLRFVWGRTRLP-RTIADFRGRDFVIQVldkyNPPDHFLPESYTCFFLLKLPRYSCKQVLEEKLKYAIHFCKSIDT 4800
           *************.8*************999988888***********************************99875 PP
   
Organism Taeniopygia guttata
Protein Sequence
(Fasta)
MSSDSFCLSA QARFDSKWLK TDLQLAFTRD GLCGLWNEMV KDGEIVYPGT ELIQSGELPP 60
RKDDSTECQT LSKKEEQNDK EKKDEEETPL PTYRAKSIVE SWVWGKQPDV NELKECLQVL 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Tgu-116789|E3,HECT|Taeniopygia guttata
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGTCTTCTG ATTCTTTTTG TCTGTCTGCT CAAGCAAGGT TTGACTCCAA ATGGTTGAAG 60
ACAGACTTGC AGGTAAGGAC TTTGATGGTC ATATTCCATT GTGACCTTTC AGGTGCTGTT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Tgu-116789|E3,HECT|Taeniopygia guttata
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR004939--APC_su10/DOC_dom
IPR021097--CPH_domain
IPR001199--Cyt_B5-like_heme/steroid-bd
IPR008979--Galactose-bd-like
IPR000569--HECT_dom
IPR010606--Mib_Herc2
IPR009091--RCC1/BLIP-II
IPR000408--Reg_chr_condens
IPR014722--Rib_L2_dom2
IPR000433--Znf_ZZ
PROSITE

PS50255--CYTOCHROME_B5_2
PS51284--DOC
PS50237--HECT
PS51416--MIB_HERC2
PS00626--RCC1_2
PS50012--RCC1_3
PS01357--ZF_ZZ_1
PS50135--ZF_ZZ_2
Pfam

PF03256--ANAPC10
PF11515--Cul7
PF00173--Cyt-b5
PF00632--HECT
PF06701--MIB_HERC2
PF00415--RCC1
PF00569--ZZ
PRINTS

PR00633--RCCNDNSATION
SMART

SM01337--APC10
SM01117--Cyt-b5
SM00119--HECTc
SM00291--ZnF_ZZ
Gene Ontology

GO:0005743--C:mitochondrial inner membrane
GO:0005634--C:nucleus
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0006974--P:cellular response to DNA damage stimulus
GO:0007283--P:spermatogenesis
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002112 Ailuropoda melanoleuca 91.14 0.00e+00 6842.00
IUUC-Atr-003065 Amborella trichopoda 35.29 2.00e-51 197.00
IUUC-Apl-003983 Anas platyrhynchos 98.37 0.00e+00 8989.00
IUUC-Aca-004300 Anolis carolinensis 94.67 0.00e+00 8640.00
IUUC-Aly-006441 Arabidopsis lyrata 34.15 5.00e-45 176.00
IUUC-Ame-010621 Astyanax mexicanus 87.81 0.00e+00 7149.00
IUUC-Bta-013067 Bos taurus 90.29 0.00e+00 8231.00
IUUC-Bdi-014093 Brachypodium distachyon 33.98 2.00e-50 194.00
IUUC-Bol-015203 Brassica oleracea 34.27 1.00e-52 201.00
IUUC-Cja-019687 Callithrix jacchus 89.45 0.00e+00 8058.00
IUUC-Cfa-020672 Canis familiaris 91.08 0.00e+00 8308.00
IUUC-Cpo-021819 Cavia porcellus 88.31 0.00e+00 8025.00
IUUC-Csa-023817 Chlorocebus sabaeus 91.02 0.00e+00 8272.00
IUUC-Cho-024387 Choloepus hoffmanni 91.45 0.00e+00 1827.00
IUUC-Cin-025709 Ciona intestinalis 55.00 0.00e+00 2229.00
IUUC-Csv-026336 Ciona savignyi 42.36 0.00e+00 3011.00
IUUC-Dre-027717 Danio rerio 84.31 0.00e+00 7481.00
IUUC-Dno-029296 Dasypus novemcinctus 91.19 0.00e+00 8271.00
IUUC-Dor-030979 Dipodomys ordii 85.26 0.00e+00 2751.00
IUUC-Dme-032171 Drosophila melanogaster 71.83 0.00e+00 1269.00
IUUC-Ete-032687 Echinops telfairi 85.44 0.00e+00 2685.00
IUUC-Eca-034046 Equus caballus 90.28 0.00e+00 8244.00
IUUC-Eeu-034859 Erinaceus europaeus 91.76 0.00e+00 1896.00
IUUC-Fca-036262 Felis catus 91.04 0.00e+00 8331.00
IUUC-Fal-037562 Ficedula albicollis 99.40 0.00e+00 8975.00
IUUC-Gmo-039054 Gadus morhua 88.52 0.00e+00 1117.00
IUUC-Gga-040359 Gallus gallus 98.35 0.00e+00 8926.00
IUUC-Gac-041879 Gasterosteus aculeatus 92.38 0.00e+00 1055.00
IUUC-Ggo-044692 Gorilla gorilla 94.32 0.00e+00 4215.00
IUUC-Hsa-045995 Homo sapiens 91.14 0.00e+00 8330.00
IUUC-Itr-048553 Ictidomys tridecemlineatus 87.10 0.00e+00 2248.00
IUUC-Lch-049808 Latimeria chalumnae 89.17 0.00e+00 3422.00
IUUC-Loc-052685 Lepisosteus oculatus 87.36 0.00e+00 7830.00
IUUC-Laf-053372 Loxodonta africana 90.15 0.00e+00 8207.00
IUUC-Mcc-054693 Macaca mulatta 91.06 0.00e+00 8307.00
IUUC-Meu-056660 Macropus eugenii 97.67 0.00e+00 1946.00
IUUC-Mga-059371 Meleagris gallopavo 98.24 0.00e+00 7684.00
IUUC-Mmr-060787 Microcebus murinus 91.28 0.00e+00 8377.00
IUUC-Mdo-062518 Monodelphis domestica 92.22 0.00e+00 8303.00
IUUC-Mmu-063690 Mus musculus 89.94 0.00e+00 8193.00
IUUC-Mpu-066478 Mustela putorius furo 90.63 0.00e+00 8254.00
IUUC-Mlu-067596 Myotis lucifugus 86.42 0.00e+00 4209.00
IUUC-Nle-069445 Nomascus leucogenys 88.01 0.00e+00 2021.00
IUUC-Opr-070990 Ochotona princeps 85.87 0.00e+00 2925.00
IUUC-Ont-072285 Oreochromis niloticus 85.90 0.00e+00 7593.00
IUUC-Oan-072721 Ornithorhynchus anatinus 87.53 0.00e+00 3488.00
IUUC-Ocu-074273 Oryctolagus cuniculus 90.38 0.00e+00 8237.00
IUUC-Obr-076107 Oryza brachyantha 33.77 4.00e-50 192.00
IUUC-Ogl-077193 Oryza glaberrima 33.68 1.00e-45 178.00
IUUC-Oin-079609 Oryza indica 32.75 3.00e-49 190.00
IUUC-Olo-080629 Oryza longistaminata 33.68 1.00e-45 178.00
IUUC-Opu-084137 Oryza punctata 33.94 2.00e-46 181.00
IUUC-Osa-085597 Oryza sativa 33.68 1.00e-45 178.00
IUUC-Ola-087346 Oryzias latipes 93.98 0.00e+00 1206.00
IUUC-Oga-088742 Otolemur garnettii 90.33 0.00e+00 8172.00
IUUC-Oar-090093 Ovis aries 90.55 0.00e+00 8235.00
IUUC-Ptr-091034 Pan troglodytes 86.54 0.00e+00 5487.00
IUUC-Pan-092783 Papio anubis 88.94 0.00e+00 8086.00
IUUC-Psi-094027 Pelodiscus sinensis 96.10 0.00e+00 8388.00
IUUC-Pfo-096208 Poecilia formosa 82.81 0.00e+00 6203.00
IUUC-Pab-097681 Pongo abelii 86.02 0.00e+00 2406.00
IUUC-Pca-100705 Procavia capensis 92.88 0.00e+00 1140.00
IUUC-Pva-103147 Pteropus vampyrus 80.71 0.00e+00 2361.00
IUUC-Rno-105458 Rattus norvegicus 89.90 0.00e+00 8184.00
IUUC-Sha-106959 Sarcophilus harrisii 83.71 0.00e+00 7192.00
IUUC-Sit-109917 Setaria italica 36.47 1.00e-48 187.00
IUUC-Sly-110961 Solanum lycopersicum 35.33 1.00e-53 204.00
IUUC-Sar-113532 Sorex araneus 83.00 0.00e+00 1792.00
IUUC-Sbi-114352 Sorghum bicolor 32.39 9.00e-50 191.00
IUUC-Ssc-115337 Sus scrofa 85.21 0.00e+00 2791.00
IUUC-Tru-118129 Takifugu rubripes 84.87 0.00e+00 7634.00
IUUC-Tsy-119302 Tarsius syrichta 80.79 0.00e+00 1222.00
IUUC-Tni-120374 Tetraodon nigroviridis 83.47 0.00e+00 7465.00
IUUC-Tca-121094 Theobroma cacao 35.59 1.00e-54 207.00
IUUC-Tae-124157 Triticum aestivum 33.51 1.00e-49 191.00
IUUC-Tbe-128137 Tupaia belangeri 82.29 0.00e+00 2189.00
IUUC-Ttr-128273 Tursiops truncatus 86.54 0.00e+00 4835.00
IUUC-Vpa-130471 Vicugna pacos 80.87 0.00e+00 1448.00
IUUC-Xtr-132185 Xenopus tropicalis 88.34 0.00e+00 7967.00
IUUC-Xma-133233 Xiphophorus maculatus 85.19 0.00e+00 7559.00
Created Date 25-Jun-2017

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