iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000005080.3	ENSMMUT00000069997.1	ENSMMUP00000059717.1
ENSMMUG00000005080.3	ENSMMUT00000007165.3	ENSMMUP00000006733.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	5.80e-49	166.5	19	161

Active Site

Position(s)	Description	Evidence
93	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 8    elekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilk......... 87
           +l+k+p+eg+sa++ d++dl++wevli+Gp+dt YeggvFk++++fp+dYP++PPk+kf+t+i+hPnv++nG+vC+sil+         
   Q: 19   KLNKNPVEGFSAGLIDDNDLYRWEVLIIGPPDTLYEGGVFKAHLTFPKDYPLRPPKMKFITEIWHPNVDKNGDVCISILHepgedkygy 107
           799****************************************************************************8888899999 PP
   S: 88   ..eeekWspalsvesvllsiqsllaepnpesplneeaaellkknre.eykkkvr 138
             +ee+W p ++ve++++s++s+la+pn +sp+n++aa++++++r+ e+k+kv 
   Q: 108  ekPEERWLPIHTVETIMISVISMLADPNGDSPANVDAAKEWREDRNgEFKRKVA 161
           999******************************************989999985 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

KTYGTSAVLV LRDGWAHRKL NKNPVEGFSA GLIDDNDLYR WEVLIIGPPD TLYEGGVFKA 60
HLTFPKDYPL RPPKMKFITE IWHPNVDKNG DVCISILHEP GEDKYGYEKP EERWLPIHTV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCTCAGCGCG CCTGCGCCGA GCGGCCCTGC GCGCAGTGAG GCAGTGGCGG GGGAAGGCAC 60
CGGTGGGGCC GACGGGCGGG TTGAAGGAGG GAAGCGGGCG AGCGAAGTCC CAGTGCGCGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0070062--C:extracellular exosome
GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0070936--P:protein K48-linked ubiquitination
GO:0070534--P:protein K63-linked ubiquitination
GO:0000209--P:protein polyubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000411	Aegilops tauschii	46.93	2.00e-41	161.00
IUUC-Aml-001379	Ailuropoda melanoleuca	99.35	8.00e-90	322.00
IUUC-Atr-003150	Amborella trichopoda	63.16	3.00e-46	176.00
IUUC-Apl-003579	Anas platyrhynchos	99.35	5.00e-90	323.00
IUUC-Aca-005146	Anolis carolinensis	99.35	1.00e-89	321.00
IUUC-Aly-005452	Arabidopsis lyrata	65.33	1.00e-51	195.00
IUUC-Ath-007258	Arabidopsis thaliana	64.00	1.00e-50	192.00
IUUC-Afl-008660	Aspergillus flavus	59.86	1.00e-46	178.00
IUUC-Aor-009951	Aspergillus oryzae	59.86	1.00e-46	178.00
IUUC-Bta-013324	Bos taurus	100.00	6.00e-89	319.00
IUUC-Bdi-014838	Brachypodium distachyon	59.52	1.00e-51	195.00
IUUC-Bol-016592	Brassica oleracea	64.47	7.00e-53	199.00
IUUC-Bra-017324	Brassica rapa	64.47	1.00e-52	198.00
IUUC-Cel-018162	Caenorhabditis elegans	74.67	4.00e-67	246.00
IUUC-Cja-018734	Callithrix jacchus	99.35	6.00e-90	322.00
IUUC-Cfa-020846	Canis familiaris	99.35	3.00e-90	323.00
IUUC-Cpo-022207	Cavia porcellus	99.35	2.00e-89	320.00
IUUC-Cre-022895	Chlamydomonas reinhardtii	67.11	5.00e-54	203.00
IUUC-Csa-024193	Chlorocebus sabaeus	100.00	6.00e-89	319.00
IUUC-Cho-024621	Choloepus hoffmanni	59.48	4.00e-43	167.00
IUUC-Cin-025131	Ciona intestinalis	70.20	1.00e-62	231.00
IUUC-Csv-026074	Ciona savignyi	74.17	4.00e-67	246.00
IUUC-Cne-026796	Cryptococcus neoformans	56.52	3.00e-45	174.00
IUUC-Cme-027321	Cyanidioschyzon merolae	56.29	4.00e-47	180.00
IUUC-Dre-028653	Danio rerio	93.45	6.00e-90	322.00
IUUC-Dno-029479	Dasypus novemcinctus	100.00	6.00e-89	319.00
IUUC-Dse-031230	Dothistroma septosporum	53.70	1.00e-47	182.00
IUUC-Dme-032132	Drosophila melanogaster	84.25	6.00e-72	262.00
IUUC-Ete-032885	Echinops telfairi	100.00	3.00e-87	313.00
IUUC-Eca-034057	Equus caballus	99.35	2.00e-89	320.00
IUUC-Eeu-035128	Erinaceus europaeus	77.92	2.00e-63	234.00
IUUC-Fca-035835	Felis catus	99.35	8.00e-90	322.00
IUUC-Fal-036778	Ficedula albicollis	100.00	6.00e-89	319.00
IUUC-Gmo-039029	Gadus morhua	90.53	5.00e-86	309.00
IUUC-Gga-040950	Gallus gallus	100.00	6.00e-89	319.00
IUUC-Gac-042438	Gasterosteus aculeatus	95.48	7.00e-85	305.00
IUUC-Gma-044131	Glycine max	66.00	1.00e-45	175.00
IUUC-Ggo-044826	Gorilla gorilla	100.00	6.00e-89	319.00
IUUC-Hsa-046638	Homo sapiens	100.00	6.00e-89	319.00
IUUC-Hvu-047065	Hordeum vulgare	59.87	2.00e-48	185.00
IUUC-Itr-048581	Ictidomys tridecemlineatus	100.00	7.00e-69	251.00
IUUC-Lch-050446	Latimeria chalumnae	94.05	1.00e-90	324.00
IUUC-Lpe-051124	Leersia perrieri	63.27	1.00e-49	188.00
IUUC-Loc-052277	Lepisosteus oculatus	100.00	6.00e-89	319.00
IUUC-Lma-053320	Leptosphaeria maculans	58.00	7.00e-47	179.00
IUUC-Laf-053491	Loxodonta africana	100.00	6.00e-89	319.00
IUUC-Meu-056870	Macropus eugenii	98.05	1.00e-83	301.00
IUUC-Mtr-058406	Medicago truncatula	64.00	3.00e-51	194.00
IUUC-Mla-059165	Melampsora laricipopulina	57.06	5.00e-54	203.00
IUUC-Mga-060005	Meleagris gallopavo	99.35	1.00e-89	321.00
IUUC-Mvi-060318	Microbotryum violaceum	65.36	2.00e-54	204.00
IUUC-Mmr-061442	Microcebus murinus	100.00	6.00e-89	319.00
IUUC-Mdo-062364	Monodelphis domestica	92.26	9.00e-89	318.00
IUUC-Mmu-064163	Mus musculus	100.00	6.00e-89	319.00
IUUC-Mac-065294	Musa acuminata	62.50	1.00e-50	192.00
IUUC-Mpu-066561	Mustela putorius furo	93.49	8.00e-91	325.00
IUUC-Mlu-067331	Myotis lucifugus	100.00	6.00e-89	319.00
IUUC-Nle-069559	Nomascus leucogenys	100.00	7.00e-56	207.00
IUUC-Opr-070958	Ochotona princeps	100.00	2.00e-89	320.00
IUUC-Ont-071843	Oreochromis niloticus	91.07	7.00e-88	315.00
IUUC-Oan-073302	Ornithorhynchus anatinus	100.00	7.00e-56	207.00
IUUC-Ocu-074321	Oryctolagus cuniculus	99.35	1.00e-89	321.00
IUUC-Oba-075155	Oryza barthii	63.27	2.00e-49	187.00
IUUC-Obr-076863	Oryza brachyantha	61.90	6.00e-49	186.00
IUUC-Ogl-077935	Oryza glaberrima	63.27	2.00e-49	187.00
IUUC-Ogu-078510	Oryza glumaepatula	63.27	2.00e-49	187.00
IUUC-Oin-080104	Oryza indica	63.27	2.00e-49	187.00
IUUC-Olo-080294	Oryza longistaminata	63.27	2.00e-49	187.00
IUUC-Ome-081190	Oryza meridionalis	58.33	4.00e-52	197.00
IUUC-Oni-082689	Oryza nivara	63.27	2.00e-49	187.00
IUUC-Opu-083784	Oryza punctata	63.27	2.00e-49	187.00
IUUC-Oru-084660	Oryza rufipogon	63.27	2.00e-49	187.00
IUUC-Osa-086247	Oryza sativa	63.27	2.00e-49	187.00
IUUC-Ola-087259	Oryzias latipes	96.73	1.00e-86	311.00
IUUC-Olu-087887	Ostreococcus lucimarinus	62.58	3.00e-60	224.00
IUUC-Oga-088473	Otolemur garnettii	99.35	6.00e-90	322.00
IUUC-Oar-090047	Ovis aries	99.35	1.00e-89	321.00
IUUC-Ptr-091331	Pan troglodytes	100.00	2.00e-89	320.00
IUUC-Pan-092230	Papio anubis	100.00	6.00e-89	319.00
IUUC-Psi-093996	Pelodiscus sinensis	98.73	2.00e-90	323.00
IUUC-Ppa-095611	Physcomitrella patens	61.21	5.00e-57	213.00
IUUC-Pfo-096159	Poecilia formosa	91.67	2.00e-88	317.00
IUUC-Pab-098727	Pongo abelii	100.00	6.00e-89	319.00
IUUC-Pop-099881	Populus trichocarpa	66.45	2.00e-55	207.00
IUUC-Pca-100369	Procavia capensis	99.33	2.00e-85	308.00
IUUC-Ppe-101778	Prunus persica	66.00	6.00e-52	196.00
IUUC-Pva-103074	Pteropus vampyrus	100.00	3.00e-89	321.00
IUUC-Pgr-103274	Puccinia graminis	57.03	1.00e-42	165.00
IUUC-Rno-104929	Rattus norvegicus	100.00	6.00e-89	319.00
IUUC-Sha-106753	Sarcophilus harrisii	92.26	9.00e-89	318.00
IUUC-Sja-107917	Schizosaccharomyces japonicus	69.09	1.00e-44	172.00
IUUC-Spo-108104	Schizosaccharomyces pombe	67.11	2.00e-59	221.00
IUUC-Smo-109401	Selaginella moellendorffii	57.83	3.00e-42	164.00
IUUC-Sit-110784	Setaria italica	63.95	7.00e-50	189.00
IUUC-Sly-111843	Solanum lycopersicum	60.00	4.00e-52	196.00
IUUC-Stu-112654	Solanum tuberosum	64.38	2.00e-50	191.00
IUUC-Sar-113227	Sorex araneus	60.65	2.00e-46	177.00
IUUC-Sbi-113787	Sorghum bicolor	62.50	1.00e-50	192.00
IUUC-Sre-114933	Sporisorium reilianum	59.87	5.00e-50	189.00
IUUC-Ssc-115912	Sus scrofa	99.35	1.00e-89	321.00
IUUC-Tgu-116635	Taeniopygia guttata	99.35	1.00e-89	321.00
IUUC-Tru-117873	Takifugu rubripes	89.02	9.00e-84	301.00
IUUC-Tsy-119168	Tarsius syrichta	100.00	1.00e-89	322.00
IUUC-Tni-119853	Tetraodon nigroviridis	89.09	6.00e-83	299.00
IUUC-Tca-121649	Theobroma cacao	63.51	1.00e-50	192.00
IUUC-Tae-123772	Triticum aestivum	62.50	2.00e-50	191.00
IUUC-Tur-126873	Triticum urartu	61.97	5.00e-47	181.00
IUUC-Tbe-127917	Tupaia belangeri	100.00	2.00e-89	320.00
IUUC-Ttr-128609	Tursiops truncatus	100.00	1.00e-88	318.00
IUUC-Uma-129506	Ustilago maydis	60.51	9.00e-51	192.00
IUUC-Vpa-130208	Vicugna pacos	100.00	6.00e-90	323.00
IUUC-Vvi-131730	Vitis vinifera	64.86	9.00e-52	195.00
IUUC-Xtr-131942	Xenopus tropicalis	99.35	1.00e-88	318.00
IUUC-Xma-134050	Xiphophorus maculatus	91.67	2.00e-88	317.00
IUUC-Zma-135532	Zea mays	63.95	2.00e-50	191.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence