iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ame-010781

Ensembl Protein ID

ENSAMXP00000009243.1

UniProt Accession

W5KNT1; W5KNT1_ASTMX

Genbank Protein ID

ENSAMXP00000009243

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

APWO01079188

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMXG00000008993.1	ENSAMXT00000009243.1	ENSAMXP00000009243.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	5.80e-107	358.0	731	1568

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsg 86
           tGl+NlgNtC+mNS +Qc sn+++l++++ + ++  +ln++np ++ g+++k++ +l++elw++++k+++p +l  +++k+a++f+g
   Q: 731  TGLSNLGNTCFMNSSIQCVSNTKPLTDYFISgRHLYELNRTNPIGMRGHMAKCYGDLVQELWSGTQKNIAPLKLRWTIAKYAPRFNG 817
           7******************************9******************************************************* PP
   S: 87   yeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde.....aeekkkkknkslisdlFqgqlksqikclecdnvssreep 168
           ++qqD+qE+laflld+l+e+l++ ++kp+ e++++d   ++d      a+e++ ++n+s+++dlF+gqlksq+kc++c+++s r++p
   Q: 818  FQQQDSQELLAFLLDGLHEDLNRVHEKPYVELKDSDG--RPDAevateAWENHLRRNRSIVVDLFHGQLKSQVKCKTCGHISARFDP 902
           ********************************99994..444344666*************************************** PP
   S: 169  fldlslpvpgkeetkke...................................................................... 185
           f+ lslp+p+++++++e                                                                      
   Q: 903  FNFLSLPLPMDSSMHLEitvikldgstpvryglrlnmdekytglkkqlselcglkpeqillaevhssniktfpqdnqkvrlsangfl 989
           ************99999********************************************************************** PP
   S: 186  ....................................................................................... 185
                                                                                                  
   Q: 990  cafeipvpgsptsvtsptptdttpmvngiagnshaekpglipngtagtpvrsgsdknlangmpstvvpsaseksltngipnghitpv 1076
           *************************************************************************************** PP
   S: 186  ....................................................................................... 185
                                                                                                  
   Q: 1077 qdspfigyiiamhrkmmrtelyflssqknrpslfgmplivpctvhtskkdlydavwiqvsrlasplppqeasnhaqdcddsmgyqyp 1163
           *************************************************************************************** PP
   S: 186  ...............................................................................slqdcLes 193
                                                                                          sl++cL++
   Q: 1164 ftlrvvqkdgnscswcpwyrfcrgctvecnedraalgnayiavdwdptalhlryqtsqeriveehasveqsrraqaepiSLDSCLKA 1250
           *************************************************************************************** PP
   S: 194  ftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.Ldlspfctspeekqke..... 274
           ft+eeel +++ yyc+kck ++ a+kkl+l++lP++Li+hLkRf+f +   + +k +k v+fp+  +d s f++ +e +q++     
   Q: 1251 FTSEEELGEDELYYCSKCKTHRLATKKLDLWRLPPILIVHLKRFQFVNG--RWIKSQKIVKFPRGgFDPSAFLAPREAAQSTwslqs 1335
           ********************************************99775..5569********************555544455555 PP
   S: 275  ....................................................................................... 274
                                                                                                  
   Q: 1336 hseclveelqrldrgdssvssistttvasppvsgrgtpcsirrmnsplsrssspsnspkntgrkqgrlrlpqlgsrhrlsnskenld 1422
           555555555555555555555666666666666666666666666666666666666666666666777777777777777777777 PP
   S: 275  .....................................................................................kk 276
                                                                                                + 
   Q: 1423 sssissfkesgpepehstgteveplgpgvpaesntqdtwsvdasstdcdvimvnglgqesgqsnghseasteldctshqrddiclEP 1509
           77777777777777777777888888888888888888888888888888888888888888899999999999************* PP
   S: 277  kYeLiavvvHsGslssGHYvayvknekgkWllfdDskVtevkeeevleetgstaYvlfYkrr 338
           +Y+L+a+ +HsG +++GHYv+y+kn ++kW++++Ds+++ev+ ee+ +   ++aY+lfY+++
   Q: 1510 IYDLYAISCHSGIMGGGHYVTYAKNPNDKWYCYNDSSCKEVHSEEIDT---DSAYILFYEQQ 1568
           ************************************************...********985 PP

Organism

Astyanax mexicanus

Protein Sequence
(Fasta)

MGAKESRIGF LSYDEAVRRV TDVELKRLKD AFKRTSGLSA YMTQQCFFKE VLGDGVPPKV 60
AEVIYNSFGG TPKGLHFNNL IVGLVLLTRG RDEEKAKYIF SLFANDSGSY VVRDEVENML 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGCTGCTCAG AAAGAGAGAG AGAGAGAGGG AGAAGGAGAG GGAGAGAGAG AGAGACACAC 60
ACACACACAC ACACACACAC ACACAGAGAT AGAGAGAGAG GGTGTGTGTG ATAGAGAGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0106--Calcium
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011992--EF-hand-dom_pair
IPR018247--EF_Hand_1_Ca_BS
IPR002048--EF_hand_dom
IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR028135--Ub_USP-typ
IPR029071--Ubiquitin-rel_dom
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS51283--DUSP
PS00018--EF_HAND_1
PS50222--EF_HAND_2
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF06337--DUSP
PF13499--EF-hand_7
PF14836--Ubiquitin_3
PF00443--UCH

SMART

SM00695--DUSP
SM00054--EFh

Gene Ontology

GO:0005509--F:calcium ion binding
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001611	Ailuropoda melanoleuca	72.87	0.00e+00	2014.00
IUUC-Apl-003272	Anas platyrhynchos	72.97	0.00e+00	2302.00
IUUC-Aca-005057	Anolis carolinensis	78.66	0.00e+00	2103.00
IUUC-Bta-013502	Bos taurus	71.69	0.00e+00	2179.00
IUUC-Cja-018754	Callithrix jacchus	74.77	0.00e+00	2404.00
IUUC-Cfa-020526	Canis familiaris	81.04	0.00e+00	2177.00
IUUC-Cpo-021568	Cavia porcellus	71.35	0.00e+00	2147.00
IUUC-Csa-023143	Chlorocebus sabaeus	80.86	0.00e+00	2189.00
IUUC-Cho-024603	Choloepus hoffmanni	90.15	5.00e-112	399.00
IUUC-Cin-025583	Ciona intestinalis	49.18	0.00e+00	1250.00
IUUC-Csv-026344	Ciona savignyi	46.87	0.00e+00	1178.00
IUUC-Dre-028121	Danio rerio	87.38	0.00e+00	2760.00
IUUC-Dno-029911	Dasypus novemcinctus	74.26	0.00e+00	2333.00
IUUC-Dor-030608	Dipodomys ordii	51.75	0.00e+00	933.00
IUUC-Dme-032094	Drosophila melanogaster	44.44	2.00e-120	428.00
IUUC-Ete-032639	Echinops telfairi	83.13	0.00e+00	1119.00
IUUC-Eca-034253	Equus caballus	81.36	0.00e+00	2157.00
IUUC-Eeu-035084	Erinaceus europaeus	67.54	0.00e+00	1331.00
IUUC-Fca-035474	Felis catus	79.43	0.00e+00	1698.00
IUUC-Fal-036985	Ficedula albicollis	73.42	0.00e+00	2324.00
IUUC-Gmo-039568	Gadus morhua	84.74	0.00e+00	2263.00
IUUC-Gga-040509	Gallus gallus	82.00	0.00e+00	2241.00
IUUC-Gac-041757	Gasterosteus aculeatus	79.60	0.00e+00	2538.00
IUUC-Ggo-044956	Gorilla gorilla	75.90	0.00e+00	1540.00
IUUC-Hsa-046107	Homo sapiens	80.45	0.00e+00	2213.00
IUUC-Itr-048865	Ictidomys tridecemlineatus	78.26	3.00e-177	615.00
IUUC-Lch-050681	Latimeria chalumnae	73.12	0.00e+00	2249.00
IUUC-Loc-052474	Lepisosteus oculatus	78.95	0.00e+00	2553.00
IUUC-Laf-054273	Loxodonta africana	81.10	0.00e+00	2211.00
IUUC-Mcc-054718	Macaca mulatta	81.01	0.00e+00	2213.00
IUUC-Meu-056558	Macropus eugenii	62.69	0.00e+00	1215.00
IUUC-Mga-059892	Meleagris gallopavo	74.35	0.00e+00	2316.00
IUUC-Mmr-060866	Microcebus murinus	74.65	0.00e+00	2419.00
IUUC-Mdo-062607	Monodelphis domestica	75.81	0.00e+00	2447.00
IUUC-Mmu-063797	Mus musculus	74.54	0.00e+00	2424.00
IUUC-Mpu-066121	Mustela putorius furo	75.29	0.00e+00	2422.00
IUUC-Mlu-067581	Myotis lucifugus	74.35	0.00e+00	2402.00
IUUC-Nle-069916	Nomascus leucogenys	78.42	0.00e+00	2093.00
IUUC-Opr-071073	Ochotona princeps	68.42	0.00e+00	969.00
IUUC-Ont-071310	Oreochromis niloticus	85.20	0.00e+00	2306.00
IUUC-Oan-073356	Ornithorhynchus anatinus	73.24	0.00e+00	2407.00
IUUC-Ocu-074216	Oryctolagus cuniculus	75.23	0.00e+00	2401.00
IUUC-Ola-087434	Oryzias latipes	79.55	0.00e+00	2429.00
IUUC-Oga-089034	Otolemur garnettii	73.80	0.00e+00	2307.00
IUUC-Oar-090369	Ovis aries	74.91	0.00e+00	2367.00
IUUC-Ptr-090605	Pan troglodytes	81.08	0.00e+00	2211.00
IUUC-Pan-092381	Papio anubis	80.68	0.00e+00	2134.00
IUUC-Psi-093819	Pelodiscus sinensis	75.75	0.00e+00	2373.00
IUUC-Pma-094480	Petromyzon marinus	62.93	0.00e+00	1465.00
IUUC-Pfo-096561	Poecilia formosa	84.73	0.00e+00	2256.00
IUUC-Pab-097643	Pongo abelii	78.00	0.00e+00	2106.00
IUUC-Pca-100944	Procavia capensis	66.35	0.00e+00	827.00
IUUC-Pva-102732	Pteropus vampyrus	73.74	0.00e+00	1964.00
IUUC-Rno-105113	Rattus norvegicus	80.80	0.00e+00	2192.00
IUUC-Sha-107608	Sarcophilus harrisii	58.96	2.00e-114	405.00
IUUC-Sar-113201	Sorex araneus	63.32	0.00e+00	1305.00
IUUC-Tgu-117322	Taeniopygia guttata	74.27	0.00e+00	2430.00
IUUC-Tru-118705	Takifugu rubripes	78.14	0.00e+00	686.00
IUUC-Tsy-119433	Tarsius syrichta	69.21	0.00e+00	1723.00
IUUC-Tni-120631	Tetraodon nigroviridis	82.89	0.00e+00	2193.00
IUUC-Tbe-127553	Tupaia belangeri	78.12	3.00e-175	609.00
IUUC-Ttr-128260	Tursiops truncatus	74.02	0.00e+00	2354.00
IUUC-Vpa-130479	Vicugna pacos	76.31	0.00e+00	2020.00
IUUC-Xtr-132686	Xenopus tropicalis	74.19	0.00e+00	2353.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence