iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ggo-045453

UUCD1 version

UUC-GoG-01120

Ensembl Protein ID

ENSGGOP00000021639.1

UniProt Accession

G3S0P4; G3S0P4_GORGO

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000014377.2	ENSGGOT00000024728.1	ENSGGOP00000021639.1
ENSGGOG00000014377.2	ENSGGOT00000014446.2	ENSGGOP00000014041.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.70e-62	211.3	552	1311

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 69   sprellkalkkeaeefsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde.....aeekkkkknkslisdlFqgql 150
           s  ++l++++k+a++f+g++qqD+qE+laflld+l+e+l++ ++kp+ e++e+d   ++d+     a++++ ++n+s+++dlF+gql
   Q: 552  SSLNFLRTIAKYAPRFDGFQQQDSQELLAFLLDALHEDLNRVHEKPYVELKESD--GRPDWevaaeAWDNHLRRNRSIVVDLFHGQL 636
           6678**********************************************9999..6666666777********************* PP
   S: 151  ksqikclecdnvssreepfldlslpvpgkeetkke.................................................... 185
           +sq+kc++c+++s+r++pf+ lslp+p+++ +++e                                                    
   Q: 637  RSQVKCKTCGHISVRFDPFNFLSLPLPMDSYMDLEitvikldgttpvryglrlnmdekytglkkqlrdlcglnseqillaevhdsni 723
           ******************************99999**************************************************** PP
   S: 186  ....................................................................................... 185
                                                                                                  
   Q: 724  knfpqdnqkvmlrmlymlclffilltitlsfsfgqkceldfssspstngmftlttngdlpqpifvpngmpntvvpcgteknftngmv 810
           *************************************************************************************** PP
   S: 186  ....................................................................................... 185
                                                                                                  
   Q: 811  nghmpslpdspftgyiiavhrkmirtelyflsprdnrpslfgmplivpctvhtrkkdlydavwiqvswlarplppqeasshaqdrdn 897
           *************************************************************************************** PP
   S: 186  ....................................................................................slq 188
                                                                                               +l+
   Q: 898  cmgyqypftlrvvqkdgnscawcpqysfcvkvtsskdddsltvafitlmlhppshtlegqtegsqvvdkhesveqsrraqaepiNLD 984
           *************************************************************************************** PP
   S: 189  dcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.Ldlspfcts....... 267
           +cL++ft+eeel ++++yyc+kck ++ a+kkl+l++lP++Li+hLkRf+f ++q+   k +k v+fp+e +d s f++        
   Q: 985  SCLRAFTTEEELGESEMYYCSKCKTHCLATKKLDLWRLPPFLIIHLKRFQFVNDQWI--KSQKIVKFPREsFDPSAFLVPrdlalcq 1069
           *************************************************99998776..8********************9999999 PP
   S: 268  ....................................................................................... 267
                                                                                                  
   Q: 1070 hqpltpqgdelskprirarevkkvdaqssagkedmllskspcslsanissspkgspsssrksgtscpssknsspnsspqtlgrskgr 1156
           999999999999999999999999999999999888888888888888888888888888888877777777766666666666666 PP
   S: 268  ..................peekqke.............................................................. 274
                             +                                                                    
   Q: 1157 lrlpqigsknkpsssknlD-----Askengagqiceladalsrghmrggsqpelvipqdhevalangflyeheacgngcgdgysngq 1238
           6666666666555555550.....055555555555555555555555555566666666666666666666666666666666666 PP
   S: 275  ...................kkkYeLiavvvHsGslssGHYvayvknekgkWllfdDskVtevkeeevleetgstaYvlfYkrr 338
                              k +Y+L+a+  + G    GH v  +      W ++  ++ +e++ +e+ +   ++aY+lfY+++
   Q: 1239 lgnhseedstddqredthiKPIYNLYAISEFDG--VLGHSVLTCL-----WSKYFPQSKHELHPDEIDT---DSAYILFYEQQ 1311
           6666666666777778888**************..5577666554.....888888999999*******...********985 PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

ETELPPVTAR EAKKIRREMT RTSKWMEMLG EWETYKHSSK LVDRVYKGIP MNIRGLVWSV 60
LLNIQEIKLK NPGRYQIMKE RGKRSSEHIH HIDLDVRRTL RNHVFFRDRY GAKQRELFYI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGACGGAGC TGCCTCCTGT GACTGCAAGG GAGGCGAAGG TAAGAGCCTG ATGGATGGAG 60
GGGCTGGTCC AGGGACGTAG GGACTGGGCG GGTGGTCAGT GAGGCAGAGG AAGCAGCTGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR000195--Rab-GTPase-TBC_dom
IPR028889--USP_dom

PROSITE

PS50086--TBC_RABGAP
PS50235--USP_3

Pfam

PF00566--RabGAP-TBC
PF00443--UCH

SMART

SM00164--TBC

Gene Ontology

GO:0005886--C:plasma membrane
GO:0055037--C:recycling endosome
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0060627--P:regulation of vesicle-mediated transport

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Csv-026344	Ciona savignyi	44.46	1.00e-132	468.00
IUUC-Ete-032639	Echinops telfairi	76.43	0.00e+00	1096.00
IUUC-Hsa-045803	Homo sapiens	84.02	0.00e+00	2174.00
IUUC-Itr-048865	Ictidomys tridecemlineatus	78.59	0.00e+00	960.00
IUUC-Mmr-060866	Microcebus murinus	76.98	0.00e+00	1259.00
IUUC-Ptr-090817	Pan troglodytes	83.65	0.00e+00	2192.00
IUUC-Pab-097826	Pongo abelii	79.77	0.00e+00	2026.00
IUUC-Sha-107608	Sarcophilus harrisii	73.92	1.00e-144	505.00
IUUC-Sar-113201	Sorex araneus	79.27	0.00e+00	1060.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence