iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062607

UUCD1 version

UUC-MoD-01115

Ensembl Protein ID

ENSMODP00000017669.2

UniProt Accession

F6XLI3; F6XLI3_MONDO

Protein Name

Uncharacterized protein

Gene Name

USP32

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000014128.3	ENSMODT00000017997.2	ENSMODP00000017669.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.10e-106	356.1	734	1566

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsg 86
           tGl+NlgNtC+mNS +Qc sn+++l++++ + ++  +ln++np ++kg+++k++ +l++elw++++k+v+p +l  +++k+a++f+g
   Q: 734  TGLSNLGNTCFMNSSIQCVSNTQPLTQYFISgRHLYELNRTNPIGMKGHMAKCYGDLVQELWSGTQKNVAPLKLRWTIAKYAPRFNG 820
           7******************************9******************************************************* PP
   S: 87   yeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde.....aeekkkkknkslisdlFqgqlksqikclecdnvssreep 168
           ++qqD+qE+laflld+l+e+l++ ++kp+ e++++d   ++d+     a++++ ++n+s+++dlF+gql+sq++c++c+++s+r++p
   Q: 821  FQQQDSQELLAFLLDGLHEDLNRVHEKPYVELKDSD--GRPDWevaaeAWDNHLRRNRSIVVDLFHGQLRSQVRCKTCGHISVRFDP 905
           ********************************9999..6666666777*************************************** PP
   S: 169  fldlslpvpgkeetkke...................................................................... 185
           f+ lslp+p+++ +++e                                                                      
   Q: 906  FNFLSLPLPMDSYMHLEitvikldgttpvryglrlnmdekytglkkqlsdlcglkpeqillaevhgsniknfpqdnqkvrlsvsgfl 992
           *************9999********************************************************************** PP
   S: 186  ....................................................................................... 185
                                                                                                  
   Q: 993  cafeiptpgsptsasspvqtdfsglstngmlnistngdllrptlipngmpntvvpgneknftngilnghvtsfpdspfigyiiaihr 1079
           *************************************************************************************** PP
   S: 186  ....................................................................................... 185
                                                                                                  
   Q: 1080 kmmrtelyflssqknrpslfgmplivpctvhtrkkdlydavwiqvsrlasplppqeasnhaqdcddsmgyqypftlrvvqkdgnsca 1166
           *************************************************************************************** PP
   S: 186  .................................................................slqdcLesftkeeelegenkyy 207
                                                                            +l++cL +ft eeel ++++yy
   Q: 1167 wcpwyrfcrgckidcaedrafignayiavdwdptalhlryqtsqeriveehesveqsrraqaepiNLDNCLCAFTHEEELGENEMYY 1253
           *************************************************************************************** PP
   S: 208  cekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.Ldlspfcts.......................... 267
           c+kck ++ a+kkl+l++lP++Li+hLkRf+f +   + +k +k v+fp+e +d s f++                           
   Q: 1254 CSKCKTHCLATKKLDLWRLPPILIIHLKRFQFVNG--RWIKSQKIVKFPREsFDPSAFLVPrdpalcqrklltpqgddlseprilqg 1338
           ******************************99775..5569******************9999999999999999999999999999 PP
   S: 268  ....................................................................................... 267
                                                                                                  
   Q: 1339 evkkvdlqntwttgegdmlskspsslsgniicntkgspslarksgtscpssknsspnssprtlgrskgrlrlpqigsknklsssken 1425
           999999999999999988888888888888888888888888888888777777777777666666666666666666655555555 PP
   S: 268  .peekqke.............................................................................kk 276
            +                                                                                   k 
   Q: 1426 lD-----AsrengtdqpfeladvmsrghvlggsqpelftlqdhettlangflyehdaynngcsnghmenhseedsvddqredvcvKP 1507
           50.....055555555556666666666666666666666666666666666666666666666666667777777888888888** PP
   S: 277  kYeLiavvvHsGslssGHYvayvknekgkWllfdDskVtevkeeevleetgstaYvlfYkrr 338
           +Y+L+a+ +HsG +++GHYv+y+kn ++kW++++Ds+++e++ +e+ +   ++aY+lfY+++
   Q: 1508 IYNLYAISCHSGIMGGGHYVTYAKNPNNKWYCYNDSSCKELHPDEIDT---DSAYILFYEQQ 1566
           ************************************************...********985 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MGAKESRIGF LSYEEALRRV TDVELKRLKD AFKRTCGLSC YMGQQCFIRE VLGDGVPPKV 60
AEVIYCSFGG TSKGLHFNNL IVGLVLLTRG RDEEKAKYIF SLFSNESGSY VVREEMERML 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGCGCCA AGGAGTCACG GATCGGATTC CTCAGCTACG AGGAGGCGCT GAGGAGAGGT 60
GAGGGGGGAG GGGTCGGGCC TGGGGAGGGC ACAGGCGAGA GGGGACACCC CCTCCTTCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0106--Calcium
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011992--EF-hand-dom_pair
IPR018247--EF_Hand_1_Ca_BS
IPR002048--EF_hand_dom
IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR028135--Ub_USP-typ
IPR029071--Ubiquitin-rel_dom
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS51283--DUSP
PS00018--EF_HAND_1
PS50222--EF_HAND_2
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF06337--DUSP
PF13202--EF-hand_5
PF14836--Ubiquitin_3
PF00443--UCH

SMART

SM00695--DUSP
SM00054--EFh

Gene Ontology

GO:0005829--C:cytosol
GO:0005794--C:Golgi apparatus
GO:0005509--F:calcium ion binding
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001611	Ailuropoda melanoleuca	91.55	0.00e+00	2494.00
IUUC-Apl-003272	Anas platyrhynchos	84.84	0.00e+00	2711.00
IUUC-Aca-005057	Anolis carolinensis	84.37	0.00e+00	2316.00
IUUC-Ame-010781	Astyanax mexicanus	74.71	0.00e+00	2433.00
IUUC-Bta-013502	Bos taurus	88.03	0.00e+00	2690.00
IUUC-Cja-018754	Callithrix jacchus	92.22	0.00e+00	2950.00
IUUC-Cfa-020526	Canis familiaris	92.44	0.00e+00	2917.00
IUUC-Cpo-021568	Cavia porcellus	86.83	0.00e+00	2623.00
IUUC-Csa-023143	Chlorocebus sabaeus	91.91	0.00e+00	2903.00
IUUC-Cho-024603	Choloepus hoffmanni	59.87	0.00e+00	664.00
IUUC-Cin-025583	Ciona intestinalis	50.60	0.00e+00	1265.00
IUUC-Csv-026344	Ciona savignyi	47.33	0.00e+00	1173.00
IUUC-Dre-028121	Danio rerio	77.06	0.00e+00	2395.00
IUUC-Dno-029911	Dasypus novemcinctus	91.34	0.00e+00	2862.00
IUUC-Dor-030608	Dipodomys ordii	59.72	0.00e+00	1090.00
IUUC-Dme-032094	Drosophila melanogaster	42.11	7.00e-123	436.00
IUUC-Ete-032639	Echinops telfairi	88.93	0.00e+00	1488.00
IUUC-Eca-034253	Equus caballus	92.21	0.00e+00	2881.00
IUUC-Eeu-035084	Erinaceus europaeus	78.94	0.00e+00	1553.00
IUUC-Fca-035474	Felis catus	91.64	0.00e+00	2375.00
IUUC-Fal-036985	Ficedula albicollis	85.68	0.00e+00	2670.00
IUUC-Gmo-039568	Gadus morhua	81.03	0.00e+00	2138.00
IUUC-Gga-040509	Gallus gallus	84.51	0.00e+00	2779.00
IUUC-Gac-041757	Gasterosteus aculeatus	80.82	0.00e+00	2190.00
IUUC-Ggo-044956	Gorilla gorilla	88.35	0.00e+00	1794.00
IUUC-Hsa-046107	Homo sapiens	92.28	0.00e+00	2929.00
IUUC-Itr-048865	Ictidomys tridecemlineatus	87.82	0.00e+00	1104.00
IUUC-Lch-050681	Latimeria chalumnae	78.93	0.00e+00	2428.00
IUUC-Loc-052474	Lepisosteus oculatus	78.12	0.00e+00	2499.00
IUUC-Laf-054273	Loxodonta africana	91.66	0.00e+00	2913.00
IUUC-Mcc-054718	Macaca mulatta	92.22	0.00e+00	2938.00
IUUC-Meu-056558	Macropus eugenii	75.10	0.00e+00	1470.00
IUUC-Mga-059892	Meleagris gallopavo	86.10	0.00e+00	2704.00
IUUC-Mmr-060866	Microcebus murinus	91.66	0.00e+00	2970.00
IUUC-Mmu-063797	Mus musculus	91.03	0.00e+00	2967.00
IUUC-Mpu-066121	Mustela putorius furo	92.53	0.00e+00	2984.00
IUUC-Mlu-067581	Myotis lucifugus	90.53	0.00e+00	2906.00
IUUC-Nle-069916	Nomascus leucogenys	89.61	0.00e+00	2791.00
IUUC-Opr-071073	Ochotona princeps	82.72	0.00e+00	1172.00
IUUC-Ont-071310	Oreochromis niloticus	81.85	0.00e+00	2164.00
IUUC-Oan-073356	Ornithorhynchus anatinus	90.22	0.00e+00	2913.00
IUUC-Ocu-074216	Oryctolagus cuniculus	91.91	0.00e+00	2940.00
IUUC-Ola-087434	Oryzias latipes	74.78	0.00e+00	2285.00
IUUC-Oga-089034	Otolemur garnettii	91.47	0.00e+00	2850.00
IUUC-Oar-090369	Ovis aries	92.08	0.00e+00	2930.00
IUUC-Ptr-090605	Pan troglodytes	92.47	0.00e+00	2938.00
IUUC-Pan-092381	Papio anubis	91.90	0.00e+00	2852.00
IUUC-Psi-093819	Pelodiscus sinensis	89.04	0.00e+00	2823.00
IUUC-Pma-094480	Petromyzon marinus	63.71	0.00e+00	1479.00
IUUC-Pfo-096561	Poecilia formosa	80.62	0.00e+00	2138.00
IUUC-Pab-097643	Pongo abelii	89.66	0.00e+00	2820.00
IUUC-Pca-100944	Procavia capensis	74.44	0.00e+00	982.00
IUUC-Pva-102732	Pteropus vampyrus	82.19	0.00e+00	2542.00
IUUC-Rno-105113	Rattus norvegicus	91.18	0.00e+00	2906.00
IUUC-Sha-107608	Sarcophilus harrisii	95.90	0.00e+00	729.00
IUUC-Sar-113201	Sorex araneus	79.98	0.00e+00	1617.00
IUUC-Ssc-115469	Sus scrofa	86.96	5.00e-178	616.00
IUUC-Tgu-117322	Taeniopygia guttata	86.74	0.00e+00	2808.00
IUUC-Tru-118705	Takifugu rubripes	68.86	0.00e+00	676.00
IUUC-Tsy-119433	Tarsius syrichta	83.25	0.00e+00	1931.00
IUUC-Tni-120631	Tetraodon nigroviridis	80.72	0.00e+00	2100.00
IUUC-Tbe-127553	Tupaia belangeri	87.53	0.00e+00	678.00
IUUC-Ttr-128260	Tursiops truncatus	91.37	0.00e+00	2939.00
IUUC-Vpa-130479	Vicugna pacos	93.47	0.00e+00	2290.00
IUUC-Xtr-132686	Xenopus tropicalis	83.53	0.00e+00	2637.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence