iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mlu-067581

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02024489

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000004162.2	ENSMLUT00000004175.2	ENSMLUP00000003800.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	8.30e-107	357.3	718	1554

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsg 86
           tGl+NlgNtC+mNS +Qc sn+++l++++ + ++  +ln++np ++kg+++k++ +l++elw++++k+++p +l  +++k+a++f+g
   Q: 718  TGLSNLGNTCFMNSSIQCVSNTQPLTQYFISgRHLYELNRTNPIGMKGHMAKCYGDLVQELWSGTQKNIAPLKLRWTIAKYAPRFNG 804
           7******************************9******************************************************* PP
   S: 87   yeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde.....aeekkkkknkslisdlFqgqlksqikclecdnvssreep 168
           ++qqD+qE+laflld+l+e+l++ ++kp+ e+++++   ++d+     a++++ ++n+s+++dlF+gql+sq+kc++c+++s+r++p
   Q: 805  FQQQDSQELLAFLLDGLHEDLNRVHEKPYVELKDSN--GRPDWevaaeAWDNHLRRNRSIVVDLFHGQLRSQVKCKTCGHISVRFDP 889
           ********************************8888..6666667777*************************************** PP
   S: 169  fldlslpvpgkeetkke...................................................................... 185
           f+ lslp+p+++ +++e                                                                      
   Q: 890  FNFLSLPLPMDSYMHLEitvikldgttpvryglrlnmdekytglkkqlsdlcglkseqillaevhgsniknfpqdnqkvrlsvsgyl 976
           *************9999********************************************************************** PP
   S: 186  ....................................................................................... 185
                                                                                                  
   Q: 977  cafeipipgspvsasspiltdissspstngmltlttngdlprpifipngmpntvvpcgteksftngmvnghmpslpdnpftgyiiav 1063
           *************************************************************************************** PP
   S: 186  ....................................................................................... 185
                                                                                                  
   Q: 1064 hrkmmrtelyflssqknrpslfgmplivpctvhtrkkdlydsvwiqvsrlasplppqeasnhaqdcddsmgyqypftlrvvqkdgns 1150
           *************************************************************************************** PP
   S: 186  ...................................................................slqdcLesftkeeelegenk 205
                                                                              +l++cL++ft+eeel ++++
   Q: 1151 cawcpwyrfcrgckidcgedkafignayiavdwdptalhlryqtsqervvdehesveqsrraqaepiNLDNCLRAFTSEEELGENEM 1237
           *************************************************************************************** PP
   S: 206  yycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.Ldlspfcts........................ 267
           yyc+kck ++ a+kkl+l++lP+vLi+hLkRf+f +   + +k +k v+fp+e +d s f++                         
   Q: 1238 YYCSKCKTHCLATKKLDLWRLPPVLIIHLKRFQFVNG--RWIKSQKIVKFPREsFDPSAFLVPrnpalcqqkpltpqgddfcetrvp 1322
           ********************************99775..5569****************9999899999999999999999999999 PP
   S: 268  ....................................................................................... 267
                                                                                                  
   Q: 1323 tgevkkmdaqnsageedvrlskspsslsaniisspkgspsssrkggascpssknsspnssprtlgrskgrlrlpqigsknkltsske 1409
           998888888888888888888888888888888888887777777777777766666666666666666666666666655555555 PP
   S: 268  ..peekqke.............................................................................. 274
             +                                                                                    
   Q: 1410 nlD-----Askengtvhvceladalsqghmlggsqpelvtpqdhevalangflyeheaygsvcgngysngqlenhseedstddqrkd 1491
           550.....0555555555566666666666666666666666666666666666666666666666666666666667777777888 PP
   S: 275  ...kkkYeLiavvvHsGslssGHYvayvknekgkWllfdDskVtevkeeevleetgstaYvlfYkr 337
              + +Y+L+a+ +HsG l++GHYv+y+kn + kW++++Ds+++e++ +e+ +   ++aY+lfY++
   Q: 1492 irvNPIYNLYAISCHSGILGGGHYVTYAKNPNSKWYCYNDSSCKELHPDEIDT---DSAYILFYEQ 1554
           888**************************************************...********98 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

VTDVELKRLK DAFKRTCGLS YYMGQHCFIK EVLGDGVPPK VAEVIYCSFG GTSKGLHFNN 60
LIVGLVLLTR GKDEEKAKYI FSLFASESGS YVTREEMERM LHVVDGKVPD TLRKCFSEGE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTTACAGATG TAGAGCTGAA GCGACTGAAA GATGCCTTCA AGAGGACCTG TGGACTCTCA 60
TATTACATGG GCCAGCACTG CTTTATCAAG GAAGTGCTTG GGGATGGAGT GCCTCCAAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0106--Calcium
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011992--EF-hand-dom_pair
IPR018247--EF_Hand_1_Ca_BS
IPR002048--EF_hand_dom
IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR028135--Ub_USP-typ
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS51283--DUSP
PS00018--EF_HAND_1
PS50222--EF_HAND_2
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF06337--DUSP
PF13202--EF-hand_5
PF14836--Ubiquitin_3
PF00443--UCH

SMART

SM00695--DUSP
SM00054--EFh

Gene Ontology

GO:0005829--C:cytosol
GO:0005794--C:Golgi apparatus
GO:0005509--F:calcium ion binding
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001611	Ailuropoda melanoleuca	95.57	0.00e+00	2604.00
IUUC-Apl-003272	Anas platyrhynchos	82.43	0.00e+00	2641.00
IUUC-Aca-005057	Anolis carolinensis	83.28	0.00e+00	2295.00
IUUC-Ame-010781	Astyanax mexicanus	74.10	0.00e+00	2367.00
IUUC-Bta-013502	Bos taurus	91.67	0.00e+00	2801.00
IUUC-Cja-018754	Callithrix jacchus	94.79	0.00e+00	2997.00
IUUC-Cfa-020526	Canis familiaris	95.91	0.00e+00	3049.00
IUUC-Cpo-021568	Cavia porcellus	89.89	0.00e+00	2729.00
IUUC-Csa-023143	Chlorocebus sabaeus	95.16	0.00e+00	2972.00
IUUC-Cho-024603	Choloepus hoffmanni	62.05	0.00e+00	677.00
IUUC-Cin-025583	Ciona intestinalis	50.19	0.00e+00	1241.00
IUUC-Csv-026344	Ciona savignyi	46.34	0.00e+00	1136.00
IUUC-Dre-028121	Danio rerio	75.86	0.00e+00	2333.00
IUUC-Dno-029911	Dasypus novemcinctus	94.27	0.00e+00	2982.00
IUUC-Dor-030608	Dipodomys ordii	66.41	0.00e+00	676.00
IUUC-Dme-032094	Drosophila melanogaster	45.02	3.00e-123	437.00
IUUC-Ete-032639	Echinops telfairi	91.82	0.00e+00	1555.00
IUUC-Eca-034253	Equus caballus	95.73	0.00e+00	3000.00
IUUC-Eeu-035084	Erinaceus europaeus	83.88	0.00e+00	1571.00
IUUC-Fca-035474	Felis catus	95.45	0.00e+00	2494.00
IUUC-Fal-036985	Ficedula albicollis	83.56	0.00e+00	2614.00
IUUC-Gmo-039568	Gadus morhua	79.51	0.00e+00	2092.00
IUUC-Gga-040509	Gallus gallus	82.15	0.00e+00	2680.00
IUUC-Gac-041757	Gasterosteus aculeatus	80.23	0.00e+00	2152.00
IUUC-Ggo-044956	Gorilla gorilla	90.10	0.00e+00	1785.00
IUUC-Hsa-046107	Homo sapiens	95.04	0.00e+00	2992.00
IUUC-Itr-048865	Ictidomys tridecemlineatus	91.75	0.00e+00	1170.00
IUUC-Lch-050681	Latimeria chalumnae	77.64	0.00e+00	2390.00
IUUC-Loc-052474	Lepisosteus oculatus	76.08	0.00e+00	2432.00
IUUC-Laf-054273	Loxodonta africana	94.72	0.00e+00	3004.00
IUUC-Mcc-054718	Macaca mulatta	94.91	0.00e+00	2991.00
IUUC-Meu-056558	Macropus eugenii	71.94	0.00e+00	1380.00
IUUC-Mga-059892	Meleagris gallopavo	83.65	0.00e+00	2639.00
IUUC-Mmr-060866	Microcebus murinus	93.83	0.00e+00	3013.00
IUUC-Mdo-062607	Monodelphis domestica	90.53	0.00e+00	2916.00
IUUC-Mmu-063797	Mus musculus	93.40	0.00e+00	3024.00
IUUC-Mpu-066121	Mustela putorius furo	96.29	0.00e+00	3070.00
IUUC-Nle-069916	Nomascus leucogenys	92.53	0.00e+00	2893.00
IUUC-Opr-071073	Ochotona princeps	84.06	0.00e+00	1187.00
IUUC-Ont-071310	Oreochromis niloticus	80.08	0.00e+00	2116.00
IUUC-Oan-073356	Ornithorhynchus anatinus	89.02	0.00e+00	2867.00
IUUC-Ocu-074216	Oryctolagus cuniculus	94.35	0.00e+00	3002.00
IUUC-Ola-087434	Oryzias latipes	74.41	0.00e+00	2263.00
IUUC-Oga-089034	Otolemur garnettii	93.82	0.00e+00	2947.00
IUUC-Oar-090369	Ovis aries	95.54	0.00e+00	3042.00
IUUC-Ptr-090605	Pan troglodytes	95.04	0.00e+00	2994.00
IUUC-Pan-092381	Papio anubis	95.10	0.00e+00	2962.00
IUUC-Psi-093819	Pelodiscus sinensis	85.74	0.00e+00	2730.00
IUUC-Pma-094480	Petromyzon marinus	64.01	0.00e+00	1472.00
IUUC-Pfo-096561	Poecilia formosa	79.47	0.00e+00	2081.00
IUUC-Pab-097643	Pongo abelii	94.71	0.00e+00	2895.00
IUUC-Pca-100944	Procavia capensis	76.65	0.00e+00	1034.00
IUUC-Pva-102732	Pteropus vampyrus	85.87	0.00e+00	2638.00
IUUC-Rno-105113	Rattus norvegicus	93.40	0.00e+00	3001.00
IUUC-Sha-107608	Sarcophilus harrisii	82.53	1.00e-173	602.00
IUUC-Sar-113201	Sorex araneus	82.93	0.00e+00	1681.00
IUUC-Ssc-115469	Sus scrofa	91.60	0.00e+00	658.00
IUUC-Tgu-117322	Taeniopygia guttata	84.76	0.00e+00	2724.00
IUUC-Tru-118705	Takifugu rubripes	68.97	0.00e+00	676.00
IUUC-Tsy-119433	Tarsius syrichta	81.04	0.00e+00	1441.00
IUUC-Tni-120631	Tetraodon nigroviridis	79.92	0.00e+00	2094.00
IUUC-Tbe-127553	Tupaia belangeri	87.59	0.00e+00	684.00
IUUC-Ttr-128260	Tursiops truncatus	94.47	0.00e+00	3038.00
IUUC-Vpa-130479	Vicugna pacos	90.63	0.00e+00	2845.00
IUUC-Xtr-132686	Xenopus tropicalis	82.48	0.00e+00	2577.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence