iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066121

Ensembl Protein ID

ENSMPUP00000014986.1

UniProt Accession

M3YUH6; M3YUH6_MUSPF

Genbank Protein ID

ENSMPUP00000014986

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01021582

Gene Name

Usp32

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000015097.1	ENSMPUT00000015223.1	ENSMPUP00000014986.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	8.90e-107	357.2	735	1568

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsg 86
           tGl+NlgNtC+mNS +Qc sn+++l++++ + ++  +ln++np ++kg+++k++ +l++elw++++k+v+p +l  +++k+a++f+g
   Q: 735  TGLSNLGNTCFMNSSIQCVSNTQPLTQYFISgRHLYELNRTNPIGMKGHMAKCYGDLVQELWSGTQKNVAPLKLRWTIAKYAPRFNG 821
           7******************************9******************************************************* PP
   S: 87   yeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde.....aeekkkkknkslisdlFqgqlksqikclecdnvssreep 168
           ++qqD+qE+laflld+l+e+l++ ++kp+ e++++d   ++d+     a++++ ++n+s+++dlF+gql+sq++c++c+++s+r++p
   Q: 822  FQQQDSQELLAFLLDGLHEDLNRVHEKPYVELKDSD--GRPDWevaaeAWDNHLRRNRSIVVDLFHGQLRSQVRCKTCGHISVRFDP 906
           ********************************9999..6666666777*************************************** PP
   S: 169  fldlslpvpgkeetkke...................................................................... 185
           f+ lslp+p+++ +++e                                                                      
   Q: 907  FNFLSLPLPMDSYMHLEitvikldgttpvryglrlnmdekytglkkqlsdlcglkseqillaevhgsniknfpqdnqkvrlsvsgfl 993
           *************9999********************************************************************** PP
   S: 186  ....................................................................................... 185
                                                                                                  
   Q: 994  cafeipipgspisasspiqtdfssspstngmftlttngdlprpifipngmpntvvpcgteknftngmvnghmpslpdnsftgyiiav 1080
           *************************************************************************************** PP
   S: 186  ....................................................................................... 185
                                                                                                  
   Q: 1081 hrkmmrtelyflssqknrpslfgmplivpctvhtrkkdlydavwiqvsrlasplppqeasnhaqdcddsmgyqypftlrvvqkdgns 1167
           *************************************************************************************** PP
   S: 186  ...................................................................slqdcLesftkeeelegenk 205
                                                                              +l++cL++ft+eeel ++++
   Q: 1168 cawcpwyrfcrgckidcgedrafignayiavdwdptalhlryqtsqervvdehesveqsrraqaepiNLDSCLRAFTSEEELGENEM 1254
           *************************************************************************************** PP
   S: 206  yycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.Ldlspfcts........................ 267
           yyc+kck ++ a+kkl+l++lP++Li+hLkRf+f +   + +k +k v+fp+e +d s f++                         
   Q: 1255 YYCSKCKTHCLATKKLDLWRLPPILIIHLKRFQFVNG--RWIKSQKIVKFPREsFDPSAFLVPrdpalcqrkpltpqgddlseprvp 1339
           ********************************99775..5569******************99999999999999999999999999 PP
   S: 268  ....................................................................................... 267
                                                                                                  
   Q: 1340 ggdvkkvdalnsageedvllskspsslsanivsspkgspsstrksgtscpssknsspnssprtlgrskgrlrlpqigsknklssske 1426
           999999999999999999999999999999999999998888888888888877777777777777777777777777777766666 PP
   S: 268  ...............................................................peekqke................k 275
                                                                          +     +                k
   Q: 1427 nldaskengagqvceladalsrghmlggsqtelvtpqdhevalangflyeheacgngysngqlE-----NhseedstddqredvhvK 1508
           6666666666666666666666666666666666655555555555555555555555555550.....05555555666666677* PP
   S: 276  kkYeLiavvvHsGslssGHYvayvknekgkWllfdDskVtevkeeevleetgstaYvlfYkrr 338
            +Y+L+a+ +HsG l++GHYv+y+kn + kW++++Ds+++e++ +e+ +   ++aY+lfY+++
   Q: 1509 PIYNLYAISCHSGILGGGHYVTYAKNPNSKWYCYNDSSCKELHPDEIDT---DSAYILFYEQQ 1568
           *************************************************...********985 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MGAKESRIGF LSYEEALRRV TDVELKRLKD AFKRTCGLSY YMGQHCFIRE VLGDGVPPKV 60
AEVIYCSFGG TSKGLHFNNL IVGLVLLTRG RDEEKAKYIF SLFASESGSY VIREEMERML 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNGGAG GGAGGGGAAG GGGGCGGGGT 60
GGGAGCCGGT CACGTGATTC GGCATGGAGG CGGTGGCGGC GGCCGGGAGG AGCTGCCGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0106--Calcium
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011992--EF-hand-dom_pair
IPR018247--EF_Hand_1_Ca_BS
IPR002048--EF_hand_dom
IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR028135--Ub_USP-typ
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS51283--DUSP
PS00018--EF_HAND_1
PS50222--EF_HAND_2
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF06337--DUSP
PF13202--EF-hand_5
PF14836--Ubiquitin_3
PF00443--UCH

SMART

SM00695--DUSP
SM00054--EFh

Gene Ontology

GO:0005829--C:cytosol
GO:0005794--C:Golgi apparatus
GO:0005509--F:calcium ion binding
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001611	Ailuropoda melanoleuca	99.27	0.00e+00	2699.00
IUUC-Apl-003272	Anas platyrhynchos	83.76	0.00e+00	2680.00
IUUC-Aca-005057	Anolis carolinensis	83.66	0.00e+00	2313.00
IUUC-Ame-010781	Astyanax mexicanus	74.92	0.00e+00	2422.00
IUUC-Bta-013502	Bos taurus	94.17	0.00e+00	2880.00
IUUC-Cja-018754	Callithrix jacchus	97.13	0.00e+00	3104.00
IUUC-Cfa-020526	Canis familiaris	98.93	0.00e+00	3110.00
IUUC-Cpo-021568	Cavia porcellus	91.60	0.00e+00	2774.00
IUUC-Csa-023143	Chlorocebus sabaeus	97.13	0.00e+00	3058.00
IUUC-Cho-024603	Choloepus hoffmanni	62.92	0.00e+00	706.00
IUUC-Cin-025583	Ciona intestinalis	50.63	0.00e+00	1282.00
IUUC-Csv-026344	Ciona savignyi	47.39	0.00e+00	1177.00
IUUC-Dre-028121	Danio rerio	76.61	0.00e+00	2386.00
IUUC-Dno-029911	Dasypus novemcinctus	95.98	0.00e+00	3007.00
IUUC-Dor-030608	Dipodomys ordii	67.75	0.00e+00	686.00
IUUC-Dme-032094	Drosophila melanogaster	45.02	6.00e-123	436.00
IUUC-Ete-032639	Echinops telfairi	94.63	0.00e+00	1592.00
IUUC-Eca-034253	Equus caballus	98.02	0.00e+00	3058.00
IUUC-Eeu-035084	Erinaceus europaeus	81.34	0.00e+00	1607.00
IUUC-Fca-035474	Felis catus	98.10	0.00e+00	2550.00
IUUC-Fal-036985	Ficedula albicollis	84.68	0.00e+00	2637.00
IUUC-Gmo-039568	Gadus morhua	80.62	0.00e+00	2138.00
IUUC-Gga-040509	Gallus gallus	83.51	0.00e+00	2760.00
IUUC-Gac-041757	Gasterosteus aculeatus	74.50	0.00e+00	2363.00
IUUC-Ggo-044956	Gorilla gorilla	88.67	0.00e+00	1843.00
IUUC-Hsa-046107	Homo sapiens	97.20	0.00e+00	3085.00
IUUC-Itr-048865	Ictidomys tridecemlineatus	95.48	0.00e+00	1192.00
IUUC-Lch-050681	Latimeria chalumnae	77.58	0.00e+00	2397.00
IUUC-Loc-052474	Lepisosteus oculatus	77.84	0.00e+00	2492.00
IUUC-Laf-054273	Loxodonta africana	96.76	0.00e+00	3082.00
IUUC-Mcc-054718	Macaca mulatta	97.07	0.00e+00	3087.00
IUUC-Meu-056558	Macropus eugenii	72.36	0.00e+00	1414.00
IUUC-Mga-059892	Meleagris gallopavo	84.87	0.00e+00	2678.00
IUUC-Mmr-060866	Microcebus murinus	96.29	0.00e+00	3121.00
IUUC-Mdo-062607	Monodelphis domestica	92.53	0.00e+00	2992.00
IUUC-Mmu-063797	Mus musculus	95.45	0.00e+00	3100.00
IUUC-Mlu-067581	Myotis lucifugus	96.29	0.00e+00	3091.00
IUUC-Nle-069916	Nomascus leucogenys	94.71	0.00e+00	2946.00
IUUC-Opr-071073	Ochotona princeps	85.86	0.00e+00	1212.00
IUUC-Ont-071310	Oreochromis niloticus	81.44	0.00e+00	2159.00
IUUC-Oan-073356	Ornithorhynchus anatinus	90.35	0.00e+00	2902.00
IUUC-Ocu-074216	Oryctolagus cuniculus	96.32	0.00e+00	3066.00
IUUC-Ola-087434	Oryzias latipes	81.08	0.00e+00	2092.00
IUUC-Oga-089034	Otolemur garnettii	95.40	0.00e+00	2978.00
IUUC-Oar-090369	Ovis aries	98.08	0.00e+00	3109.00
IUUC-Ptr-090605	Pan troglodytes	97.26	0.00e+00	3090.00
IUUC-Pan-092381	Papio anubis	97.00	0.00e+00	3004.00
IUUC-Psi-093819	Pelodiscus sinensis	86.89	0.00e+00	2771.00
IUUC-Pma-094480	Petromyzon marinus	64.19	0.00e+00	1482.00
IUUC-Pfo-096561	Poecilia formosa	80.29	0.00e+00	2125.00
IUUC-Pab-097643	Pongo abelii	94.39	0.00e+00	2967.00
IUUC-Pca-100944	Procavia capensis	77.58	0.00e+00	1028.00
IUUC-Pva-102732	Pteropus vampyrus	87.79	0.00e+00	2722.00
IUUC-Rno-105113	Rattus norvegicus	95.52	0.00e+00	3038.00
IUUC-Sha-107608	Sarcophilus harrisii	84.14	8.00e-177	612.00
IUUC-Sar-113201	Sorex araneus	84.74	0.00e+00	1711.00
IUUC-Ssc-115469	Sus scrofa	95.37	0.00e+00	663.00
IUUC-Tgu-117322	Taeniopygia guttata	86.13	0.00e+00	2784.00
IUUC-Tru-118705	Takifugu rubripes	68.60	0.00e+00	677.00
IUUC-Tsy-119433	Tarsius syrichta	82.23	0.00e+00	1454.00
IUUC-Tni-120631	Tetraodon nigroviridis	73.65	0.00e+00	2267.00
IUUC-Tbe-127553	Tupaia belangeri	89.06	0.00e+00	697.00
IUUC-Ttr-128260	Tursiops truncatus	96.91	0.00e+00	3105.00
IUUC-Vpa-130479	Vicugna pacos	93.06	0.00e+00	2891.00
IUUC-Xtr-132686	Xenopus tropicalis	82.85	0.00e+00	2615.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence