iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Pma-094480

UUCD1 version

UUC-PeM-00534

Ensembl Protein ID

ENSPMAP00000002068.1

UniProt Accession

S4RA37; S4RA37_PETMA

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPMAG00000001873.1	ENSPMAT00000002079.1	ENSPMAP00000002069.1
ENSPMAG00000001873.1	ENSPMAT00000002078.1	ENSPMAP00000002068.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	5.50e-71	238.7	716	1268

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsg 86
           tGl+NlgNtC+mNS +Qc sn+++l++++l+  +  +ln++np ++kg+++k++ +l++elw++++k+v+p +l  +++k+a++f+g
   Q: 716  TGLSNLGNTCFMNSSIQCVSNTRQLTQYFLSgMHLYELNRTNPLGMKGHMAKCYGDLINELWSGTQKNVAPLKLRWTIGKYAPRFNG 802
           7******************************9999**************************************************** PP
   S: 87   yeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde.....aeekkkkknkslisdlFqgqlksqikclecdnvssreep 168
           ++qqD+qE+laflld+l+e+l++ ++kp+ e++++d   ++d+     a+e++  +nks+++dlF+gqlksq++c+ cd+vs+r++p
   Q: 803  FQQQDSQELLAFLLDGLHEDLNRVHDKPYVELKDSD--GRPDHevateAWENHLLRNKSIVVDLFHGQLKSQVRCKMCDHVSVRFDP 887
           ********************************9999..5555555777*************************************** PP
   S: 169  fldlslpvpgkeetkke...................................................................... 185
           f+ lslp+p++++++ e                                                                      
   Q: 888  FNFLSLPLPMDSSMHVEitvirldgsvpvryglrlgvedkysglkqqlselcslqpqqillaevfssnirnfpddnqkvrsgatsyl 974
           *************9999********************************************************************** PP
   S: 186  ....................................................................................... 185
                                                                                                  
   Q: 975  cafeipvlsgdpastsptdahftpiggprhftfivlndnllppcfaptahistrgagglaksasngltnghlaqscrpeqlggvqps 1061
           *************************************************************************************** PP
   S: 186  ....................................................................................... 185
                                                                                                  
   Q: 1062 gyaiavhrkmmrmevyflsshknrpslfgmplivpcaagtqhchlydlvwgqvarlvsplppqeasnhaqdcddslgyqypftlsav 1148
           *************************************************************************************** PP
   S: 186  ..........................................................................slqdcLesftkee 198
                                                                                     sl++cL++ftkee
   Q: 1149 qkdgvtcawcpwyrfcrgckiecntvvfvgssgvyiaidwdptalhlryqtaqervclehesvgesrraqtepiSLNSCLQAFTKEE 1235
           *************************************************************************************** PP
   S: 199  elegenkyycekckkkqeaekklklkklPevLi 231
           el +++ yyc+kc++++ a+kkl++++lP+ L+
   Q: 1236 ELGEDELYYCSKCRAHRLASKKLDIWRLPPSLV 1268
           ******************************985 PP

Organism

Petromyzon marinus

Protein Sequence
(Fasta)

LHTVTDDELK RLRDAFKRSC GLAYMNQQCF VREVLGEGVP PKVAEVIYNS FGGSSKGLSF 60
KELVVGLVLL TRGRDEEKIK YIFSLCANES GSYVSREGLE GLLQACETQP LAETVRQCFR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTGCACACAG TGACGGATGA TGAGCTGAAG AGGCTACGCG ATGCCTTCAA ACGGTCATGT 60
GGTCTGGCGT ACATGAACCA GCAATGCTTT GTGAGGGAGG TGCTTGGGGA AGGGGTGCCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0106--Calcium

Interpro

IPR011992--EF-hand-dom_pair
IPR018247--EF_Hand_1_Ca_BS
IPR002048--EF_hand_dom
IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS51283--DUSP
PS00018--EF_HAND_1
PS50222--EF_HAND_2
PS00972--USP_1
PS50235--USP_3

Pfam

PF06337--DUSP
PF00443--UCH

SMART

SM00695--DUSP

Gene Ontology

GO:0005509--F:calcium ion binding
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001611	Ailuropoda melanoleuca	62.42	0.00e+00	1304.00
IUUC-Apl-003272	Anas platyrhynchos	63.20	0.00e+00	1531.00
IUUC-Aca-005057	Anolis carolinensis	64.32	0.00e+00	1558.00
IUUC-Ame-010781	Astyanax mexicanus	63.35	0.00e+00	1574.00
IUUC-Bta-013502	Bos taurus	61.80	0.00e+00	1459.00
IUUC-Cja-018754	Callithrix jacchus	64.19	0.00e+00	1600.00
IUUC-Cfa-020526	Canis familiaris	64.16	0.00e+00	1593.00
IUUC-Cpo-021568	Cavia porcellus	60.19	0.00e+00	1412.00
IUUC-Csa-023143	Chlorocebus sabaeus	63.71	0.00e+00	1598.00
IUUC-Cho-024603	Choloepus hoffmanni	74.62	2.00e-88	319.00
IUUC-Cin-025583	Ciona intestinalis	47.51	0.00e+00	1105.00
IUUC-Csv-026344	Ciona savignyi	44.99	0.00e+00	1003.00
IUUC-Dre-028121	Danio rerio	64.19	0.00e+00	1561.00
IUUC-Dno-029911	Dasypus novemcinctus	63.78	0.00e+00	1563.00
IUUC-Dme-032094	Drosophila melanogaster	47.57	7.00e-132	464.00
IUUC-Ete-032639	Echinops telfairi	67.92	0.00e+00	860.00
IUUC-Eca-034253	Equus caballus	63.88	0.00e+00	1578.00
IUUC-Eeu-035084	Erinaceus europaeus	55.64	9.00e-149	520.00
IUUC-Fca-035474	Felis catus	62.39	0.00e+00	1232.00
IUUC-Fal-036985	Ficedula albicollis	63.36	0.00e+00	1559.00
IUUC-Gmo-039568	Gadus morhua	64.04	0.00e+00	1528.00
IUUC-Gga-040509	Gallus gallus	63.67	0.00e+00	1603.00
IUUC-Gac-041757	Gasterosteus aculeatus	63.15	0.00e+00	1555.00
IUUC-Ggo-044956	Gorilla gorilla	61.03	0.00e+00	1145.00
IUUC-Hsa-046107	Homo sapiens	64.11	0.00e+00	1597.00
IUUC-Itr-048865	Ictidomys tridecemlineatus	60.69	3.00e-119	420.00
IUUC-Lch-050681	Latimeria chalumnae	60.38	0.00e+00	1425.00
IUUC-Loc-052474	Lepisosteus oculatus	64.65	0.00e+00	1555.00
IUUC-Laf-054273	Loxodonta africana	64.03	0.00e+00	1598.00
IUUC-Mcc-054718	Macaca mulatta	64.16	0.00e+00	1600.00
IUUC-Meu-056558	Macropus eugenii	52.53	0.00e+00	935.00
IUUC-Mga-059892	Meleagris gallopavo	63.75	0.00e+00	1534.00
IUUC-Mmr-060866	Microcebus murinus	63.18	0.00e+00	1585.00
IUUC-Mdo-062607	Monodelphis domestica	64.50	0.00e+00	1622.00
IUUC-Mmu-063797	Mus musculus	64.03	0.00e+00	1605.00
IUUC-Mpu-066121	Mustela putorius furo	64.19	0.00e+00	1601.00
IUUC-Mlu-067581	Myotis lucifugus	64.01	0.00e+00	1605.00
IUUC-Nle-069916	Nomascus leucogenys	63.17	0.00e+00	1562.00
IUUC-Opr-071073	Ochotona princeps	50.42	0.00e+00	654.00
IUUC-Ont-071310	Oreochromis niloticus	64.35	0.00e+00	1540.00
IUUC-Oan-073356	Ornithorhynchus anatinus	63.80	0.00e+00	1605.00
IUUC-Ocu-074216	Oryctolagus cuniculus	64.45	0.00e+00	1603.00
IUUC-Ola-087434	Oryzias latipes	64.48	0.00e+00	1531.00
IUUC-Oga-089034	Otolemur garnettii	63.10	0.00e+00	1535.00
IUUC-Oar-090369	Ovis aries	64.27	0.00e+00	1585.00
IUUC-Ptr-090605	Pan troglodytes	64.11	0.00e+00	1597.00
IUUC-Pan-092381	Papio anubis	63.47	0.00e+00	1566.00
IUUC-Psi-093819	Pelodiscus sinensis	64.22	0.00e+00	1587.00
IUUC-Pfo-096561	Poecilia formosa	63.29	0.00e+00	1506.00
IUUC-Pab-097643	Pongo abelii	63.70	0.00e+00	1523.00
IUUC-Pca-100944	Procavia capensis	60.46	0.00e+00	630.00
IUUC-Pva-102732	Pteropus vampyrus	59.31	0.00e+00	1454.00
IUUC-Rno-105113	Rattus norvegicus	64.11	0.00e+00	1602.00
IUUC-Sar-113201	Sorex araneus	54.86	0.00e+00	779.00
IUUC-Tgu-117322	Taeniopygia guttata	64.35	0.00e+00	1606.00
IUUC-Tru-118705	Takifugu rubripes	63.40	5.00e-166	576.00
IUUC-Tsy-119433	Tarsius syrichta	57.76	0.00e+00	831.00
IUUC-Tni-120631	Tetraodon nigroviridis	63.70	0.00e+00	1516.00
IUUC-Tbe-127553	Tupaia belangeri	83.21	9.00e-138	483.00
IUUC-Ttr-128260	Tursiops truncatus	64.39	0.00e+00	1611.00
IUUC-Vpa-130479	Vicugna pacos	63.39	0.00e+00	1496.00
IUUC-Xtr-132686	Xenopus tropicalis	64.41	0.00e+00	1575.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence