iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tru-118705

UUCD1 version

UUC-TaR-01124

Ensembl Protein ID

ENSTRUP00000017505.1

UniProt Accession

H2SYL7; H2SYL7_TAKRU

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000007122.1	ENSTRUT00000017578.1	ENSTRUP00000017504.1
ENSTRUG00000007122.1	ENSTRUT00000017579.1	ENSTRUP00000017505.1
ENSTRUG00000007122.1	ENSTRUT00000017580.1	ENSTRUP00000017506.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	5.10e-107	359.2	229	868

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgye 88
           tGl+NlgNtC+mNS +Qc sn++ l++++l+ ++  +ln++np ++ g+++k++ +l+ elw++++k+v+p +l  +++k+a++f+g++
   Q: 229  TGLSNLGNTCFMNSSIQCVSNTKALTDYFLSgRHLYELNRTNPIGMRGHMAKCYGDLVMELWSGTQKSVAPLKLRWTIAKYAPRFNGFQ 317
           7******************************9********************************************************* PP
   S: 89   qqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde.....aeekkkkknkslisdlFqgqlksqikclecdnvssreepfldl 172
           qqD+qE+laflld+l+e+l++ ++kp+ e+++++   ++d+     a+e++ ++n+s+++dlF+gqlksq+kc++c+++s r++pf+ l
   Q: 318  QQDSQELLAFLLDGLHEDLNRVHEKPYVELKDSN--GRPDWevaseAWENHLRRNRSIVVDLFHGQLKSQVKCKTCGHISARFDPFNFL 404
           ******************************8888..5565566777******************************************* PP
   S: 173  slpvpgkeetkke............................................................................ 185
           slp+p+++ +++e                                                                            
   Q: 405  SLPLPMDSYMHLEitviklegstpvryglrlnmdekymglkkqlselcslkpeqillaevhtsnikvqqnnlpviaelhliitfislqr 493
           *********9999**************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 494  qedgesstvtidlcsqmrtelyflssqknrpslfgmplivpctvhttkkdlydavwiqvsrlasplppqeasnhaqdccksqlaqllws 582
           ***************************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 583  arlnystshfsfepavmiawvtstpsryglsvktatrvpgldqttqtnglcvsrfcrgciiectddraslgnayiavdwdptalhlryq 671
           ***************************************************************************************** PP
   S: 186  ................................................slqdcLesftkeeelegenkyycekckkkqeaekklklkkl 226
                                                           sl++cL++ft+eeel +++ yyc+kck ++ a+kkl+l++l
   Q: 672  tsqicldkelisfrwlkhtvtddhikhtviveehcsveqsrraqaepiSLDSCLKAFTSEEELGEDELYYCSKCKTHRLATKKLDLWRL 760
           ***************************************************************************************** PP
   S: 227  PevLilhLkRfsfseeqksrekinkkvefple.LdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvknekgkWllfdDskV 314
           P++Li+hLkRf+f +   + +k +k v+fp + Ld ++ + +  ++   +  Y+L+a+ +HsG +++GHYv+y+kn k+kW++++Ds++
   Q: 761  PPILIVHLKRFQFVNG--RWIKSQKIVKFPNSsLDPDNSLLQHRDNMCLDAVYNLYAISCHSGIMGGGHYVTYAKNPKKKWYCYNDSSC 847
           ***********99775..5569********999****988888888888**************************************** PP
   S: 315  tevkeeevleetgstaYvlfYkrr 338
           +ev+ ee+ +   ++aY+lfY+++
   Q: 848  KEVHSEEIDT---DSAYILFYEQQ 868
           **********...********985 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

LQQGQNWFLI SMLWWQQWKD YVKYTAWEDW EPSASSAPPR PGAIDNQSLV NTDPMKLNPH 60
LVPGRDFETV PEPVWRALYH WYGANLSLPR PVSANATHNV QSVRGAEWNI QSKLCLESKR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTGCAGCAAG GCCAGAACTG GTTCCTCATC TCCATGCTGT GGTGGCAGCA GTGGAAGGAT 60
TATGTTAAAT ATGTAAGTCA AGCAGACAGT TGTTGGTTTA AACCCTTTCT GTTCCTCTGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR028135--Ub_USP-typ
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS51283--DUSP
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF06337--DUSP
PF14836--Ubiquitin_3
PF00443--UCH

SMART

SM00695--DUSP

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001611	Ailuropoda melanoleuca	75.37	0.00e+00	704.00
IUUC-Apl-003272	Anas platyrhynchos	75.64	0.00e+00	714.00
IUUC-Aca-005057	Anolis carolinensis	75.43	0.00e+00	676.00
IUUC-Ame-010781	Astyanax mexicanus	78.33	0.00e+00	694.00
IUUC-Bta-013502	Bos taurus	75.80	0.00e+00	710.00
IUUC-Bra-017213	Brassica rapa	31.04	7.00e-96	345.00
IUUC-Cel-018710	Caenorhabditis elegans	26.83	1.00e-77	285.00
IUUC-Cja-018754	Callithrix jacchus	75.37	0.00e+00	706.00
IUUC-Cfa-020526	Canis familiaris	75.59	0.00e+00	707.00
IUUC-Cpo-021568	Cavia porcellus	75.59	0.00e+00	707.00
IUUC-Csa-023143	Chlorocebus sabaeus	59.74	0.00e+00	916.00
IUUC-Cin-025583	Ciona intestinalis	53.74	5.00e-132	466.00
IUUC-Csv-026344	Ciona savignyi	48.90	6.00e-116	412.00
IUUC-Dre-028121	Danio rerio	78.34	0.00e+00	692.00
IUUC-Dno-029911	Dasypus novemcinctus	68.82	0.00e+00	707.00
IUUC-Dme-032094	Drosophila melanogaster	43.29	2.00e-106	381.00
IUUC-Ete-032639	Echinops telfairi	59.71	0.00e+00	741.00
IUUC-Eca-034253	Equus caballus	75.80	0.00e+00	709.00
IUUC-Eeu-035084	Erinaceus europaeus	72.18	6.00e-173	602.00
IUUC-Fca-035474	Felis catus	75.43	0.00e+00	707.00
IUUC-Fal-036985	Ficedula albicollis	61.24	0.00e+00	981.00
IUUC-Gmo-039568	Gadus morhua	79.40	0.00e+00	705.00
IUUC-Gga-040509	Gallus gallus	64.19	0.00e+00	742.00
IUUC-Gac-041757	Gasterosteus aculeatus	79.53	0.00e+00	737.00
IUUC-Ggo-044956	Gorilla gorilla	63.55	0.00e+00	940.00
IUUC-Hsa-046107	Homo sapiens	68.58	0.00e+00	708.00
IUUC-Lch-050681	Latimeria chalumnae	67.79	5.00e-161	562.00
IUUC-Loc-052474	Lepisosteus oculatus	75.37	0.00e+00	684.00
IUUC-Laf-054273	Loxodonta africana	75.59	0.00e+00	709.00
IUUC-Mcc-054718	Macaca mulatta	75.59	0.00e+00	707.00
IUUC-Meu-056558	Macropus eugenii	55.25	8.00e-136	479.00
IUUC-Mga-059892	Meleagris gallopavo	69.37	0.00e+00	719.00
IUUC-Mmr-060866	Microcebus murinus	73.90	0.00e+00	707.00
IUUC-Mdo-062607	Monodelphis domestica	75.80	0.00e+00	711.00
IUUC-Mmu-063797	Mus musculus	59.74	0.00e+00	920.00
IUUC-Mpu-066121	Mustela putorius furo	75.59	0.00e+00	708.00
IUUC-Mlu-067581	Myotis lucifugus	68.95	0.00e+00	713.00
IUUC-Nle-069916	Nomascus leucogenys	76.02	0.00e+00	707.00
IUUC-Ont-071310	Oreochromis niloticus	79.91	0.00e+00	707.00
IUUC-Oan-073356	Ornithorhynchus anatinus	69.10	0.00e+00	712.00
IUUC-Ocu-074216	Oryctolagus cuniculus	76.02	0.00e+00	714.00
IUUC-Ola-087434	Oryzias latipes	79.27	0.00e+00	705.00
IUUC-Oga-089034	Otolemur garnettii	75.59	0.00e+00	707.00
IUUC-Oar-090369	Ovis aries	69.13	0.00e+00	714.00
IUUC-Ptr-090605	Pan troglodytes	75.59	0.00e+00	707.00
IUUC-Pan-092381	Papio anubis	75.59	0.00e+00	707.00
IUUC-Psi-093819	Pelodiscus sinensis	69.13	0.00e+00	719.00
IUUC-Pma-094480	Petromyzon marinus	63.05	2.00e-158	553.00
IUUC-Pfo-096561	Poecilia formosa	79.35	0.00e+00	679.00
IUUC-Pab-097643	Pongo abelii	74.95	0.00e+00	701.00
IUUC-Pca-100944	Procavia capensis	49.05	1.00e-119	424.00
IUUC-Pva-102732	Pteropus vampyrus	67.27	0.00e+00	702.00
IUUC-Rno-105113	Rattus norvegicus	59.62	0.00e+00	917.00
IUUC-Sar-113201	Sorex araneus	54.46	2.00e-123	437.00
IUUC-Tgu-117322	Taeniopygia guttata	69.32	0.00e+00	716.00
IUUC-Tsy-119433	Tarsius syrichta	75.37	0.00e+00	704.00
IUUC-Tni-120631	Tetraodon nigroviridis	81.62	0.00e+00	725.00
IUUC-Tbe-127553	Tupaia belangeri	87.59	2.00e-146	513.00
IUUC-Ttr-128260	Tursiops truncatus	58.31	0.00e+00	884.00
IUUC-Vpa-130479	Vicugna pacos	75.59	0.00e+00	708.00
IUUC-Xtr-132686	Xenopus tropicalis	67.20	0.00e+00	679.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence