iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mlu-067532

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02022254

Gene Name

SOCS6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000006873.2	ENSMLUT00000006858.2	ENSMLUP00000006264.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	3.40e-17	62.1	488	535

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 2    sklwllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlyedy 52
            ++ +++ ++rSLq+LCR++Ir++++++ +   +kLPLP+++kdYL++++y
   Q: 488  TNPVSRFMQVRSLQYLCRFVIRQYTRIDLI---QKLPLPNKMKDYLQEKHY 535
           5788999********************888...***************997 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

MKKISLKTFR KSFNLTKSKE EADFMVVQQP SLASDFGKED SLFGSCYGKD MASCDINGED 60
DKGAKNRSKS ESLMGTLKRR LSAKQKQKGK GSGPSGSSAD EDTFSSSSAP LVFKDVRAQR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAAGAAAA TCAGTCTTAA AACCTTCCGG AAATCTTTCA ACTTGACTAA AAGTAAAGAA 60
GAAGCGGATT TCATGGTAGT GCAACAGCCC TCACTAGCCA GTGATTTTGG AAAAGAAGAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR028421--SOCS6
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF07525--SOCS_box

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0001772--C:immunological synapse
GO:0005622--C:intracellular
GO:0035556--P:intracellular signal transduction
GO:0050868--P:negative regulation of T cell activation
GO:0010498--P:proteasomal protein catabolic process
GO:0016567--P:protein ubiquitination
GO:0040008--P:regulation of growth

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001911	Ailuropoda melanoleuca	94.39	0.00e+00	941.00
IUUC-Apl-004035	Anas platyrhynchos	88.97	0.00e+00	869.00
IUUC-Aca-004782	Anolis carolinensis	86.38	0.00e+00	840.00
IUUC-Ame-011790	Astyanax mexicanus	69.23	0.00e+00	645.00
IUUC-Bta-012579	Bos taurus	95.22	5.00e-109	387.00
IUUC-Bol-015843	Brassica oleracea	28.77	3.10e-02	33.10
IUUC-Cel-018643	Caenorhabditis elegans	33.59	1.00e-11	62.80
IUUC-Cja-019528	Callithrix jacchus	91.78	0.00e+00	956.00
IUUC-Cfa-020678	Canis familiaris	94.95	0.00e+00	954.00
IUUC-Cpo-021947	Cavia porcellus	93.27	0.00e+00	960.00
IUUC-Csa-023935	Chlorocebus sabaeus	93.27	0.00e+00	941.00
IUUC-Cho-024477	Choloepus hoffmanni	89.35	0.00e+00	919.00
IUUC-Cin-025413	Ciona intestinalis	68.24	3.00e-66	245.00
IUUC-Csv-026247	Ciona savignyi	67.47	6.00e-65	241.00
IUUC-Dre-027636	Danio rerio	69.26	0.00e+00	645.00
IUUC-Dno-029048	Dasypus novemcinctus	92.15	0.00e+00	926.00
IUUC-Dor-030401	Dipodomys ordii	89.74	0.00e+00	902.00
IUUC-Ete-033116	Echinops telfairi	49.82	4.00e-59	221.00
IUUC-Eca-033825	Equus caballus	94.95	0.00e+00	915.00
IUUC-Fca-036253	Felis catus	93.08	0.00e+00	861.00
IUUC-Fal-037614	Ficedula albicollis	88.97	0.00e+00	868.00
IUUC-Fox-037898	Fusarium oxysporum	28.40	1.50e-02	33.10
IUUC-Gmo-038928	Gadus morhua	69.56	0.00e+00	664.00
IUUC-Gga-040177	Gallus gallus	88.41	0.00e+00	863.00
IUUC-Gac-042263	Gasterosteus aculeatus	69.56	0.00e+00	687.00
IUUC-Ggo-045288	Gorilla gorilla	92.71	0.00e+00	937.00
IUUC-Hsa-046409	Homo sapiens	93.08	0.00e+00	939.00
IUUC-Itr-048996	Ictidomys tridecemlineatus	92.34	0.00e+00	917.00
IUUC-Lch-050354	Latimeria chalumnae	83.21	0.00e+00	849.00
IUUC-Loc-052319	Lepisosteus oculatus	80.97	0.00e+00	806.00
IUUC-Laf-054070	Loxodonta africana	90.65	0.00e+00	877.00
IUUC-Mcc-055045	Macaca mulatta	93.27	0.00e+00	943.00
IUUC-Meu-055917	Macropus eugenii	89.35	0.00e+00	928.00
IUUC-Mga-059273	Meleagris gallopavo	88.79	0.00e+00	863.00
IUUC-Mmr-061597	Microcebus murinus	93.08	0.00e+00	934.00
IUUC-Mdo-062492	Monodelphis domestica	63.85	2.00e-109	388.00
IUUC-Mmu-063374	Mus musculus	83.27	0.00e+00	833.00
IUUC-Mpu-065967	Mustela putorius furo	89.72	0.00e+00	902.00
IUUC-Nle-069373	Nomascus leucogenys	93.27	0.00e+00	939.00
IUUC-Opr-070873	Ochotona princeps	90.47	0.00e+00	953.00
IUUC-Ont-072498	Oreochromis niloticus	69.93	0.00e+00	717.00
IUUC-Oan-072943	Ornithorhynchus anatinus	71.96	1.00e-97	349.00
IUUC-Ocu-073870	Oryctolagus cuniculus	92.52	0.00e+00	930.00
IUUC-Ola-086866	Oryzias latipes	90.65	6.00e-105	372.00
IUUC-Oga-089057	Otolemur garnettii	90.84	0.00e+00	907.00
IUUC-Oar-089841	Ovis aries	61.19	1.00e-164	572.00
IUUC-Ptr-091054	Pan troglodytes	93.08	0.00e+00	938.00
IUUC-Pma-094253	Petromyzon marinus	82.11	3.00e-92	332.00
IUUC-Pfo-097179	Poecilia formosa	63.96	3.00e-175	607.00
IUUC-Pab-097702	Pongo abelii	93.27	0.00e+00	939.00
IUUC-Pca-100671	Procavia capensis	84.59	8.00e-120	424.00
IUUC-Rno-106044	Rattus norvegicus	80.80	0.00e+00	823.00
IUUC-Sha-107139	Sarcophilus harrisii	88.76	0.00e+00	849.00
IUUC-Smo-108823	Selaginella moellendorffii	33.96	3.90e-02	32.00
IUUC-Sly-111748	Solanum lycopersicum	46.15	2.80e-01	30.00
IUUC-Ssc-115343	Sus scrofa	93.46	0.00e+00	958.00
IUUC-Tgu-117061	Taeniopygia guttata	88.41	0.00e+00	864.00
IUUC-Tni-119829	Tetraodon nigroviridis	66.17	0.00e+00	639.00
IUUC-Tae-123723	Triticum aestivum	27.50	5.70e-02	33.10
IUUC-Ttr-129148	Tursiops truncatus	92.71	0.00e+00	907.00
IUUC-Vpa-130780	Vicugna pacos	90.28	0.00e+00	870.00
IUUC-Vvi-130966	Vitis vinifera	32.69	6.60e-02	31.20
IUUC-Xtr-132513	Xenopus tropicalis	80.75	0.00e+00	832.00
IUUC-Xma-133904	Xiphophorus maculatus	67.65	0.00e+00	661.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence