iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ggo-045002

UUCD1 version

UUC-GoG-01083

Ensembl Protein ID

ENSGGOP00000002734.2

UniProt Accession

G3QJX5; G3QJX5_GORGO

Protein Name

Uncharacterized protein

Gene Name

USP15

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000002771.2	ENSGGOT00000002792.2	ENSGGOP00000002734.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	4.40e-120	401.3	260	904
ULD/UDP/UBQ/UBQ_Other	7.00e-10	39.1	118	188

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgye 88
           +Gl+NlgNtC+mNS++QcLsn+p+l+e++l+ k++e+ln +np ++ ge++ks+++l++++w++k ++v+pr+++++++++a++fsgy+
   Q: 260  CGLSNLGNTCFMNSAIQCLSNTPPLTEYFLNdKYQEELNFDNPLGMRGEIAKSYAELIKQMWSGKFSYVTPRAFKTQVGRFAPQFSGYQ 348
           7******************************9********************************************************* PP
   S: 89   qqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde.....aeekkkkknkslisdlFqgqlksqikclecdnvssreepfldl 172
           qqD+qE+laflld+l+e+l++ ++kp+ +++++d   ++d+     a+e++ k+n+s+i+d+F+g +ks+++c+ec+++s++++pf++l
   Q: 349  QQDCQELLAFLLDGLHEDLNRIRKKPYIQLKDAD--GRPDKvvaeeAWENHLKRNDSIIVDIFHGLFKSTLVCPECAKISVTFDPFCYL 435
           ******************************9999..5555555777******************************************* PP
   S: 173  slpvpgkeetkke............................................................................ 185
           +lp+p+k+e+ +e                                                                            
   Q: 436  TLPLPMKKERTLEvylvrmdpltkpmqykvvvpkignildlctalsalsgipadkmivtdiynhrfhrifamdenlssimerddiyvfe 524
           *********9999**************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 525  ininrtedtehviipvclrekfrhssythhtgsslfgqpflmavprnntedklynllllrmcryvkisteteetegslhcckdqningn 613
           ***************************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 614  gpngiheegspsemetdepddessqdqelpsenensqsedsvggdndsenglctedtckgqltghkkrlftfqfnnlgntdinyikddt 702
           ***************************************************************************************** PP
   S: 186  .......................................................slqdcLesftkeeelegenkyycekckkkqeaek 219
                                                                  +l+dc+e ft++e+l  e+ +yc++ck++q+a+k
   Q: 703  rhirfddrqlrldersflaldwdpdlkkryfdenaaedfekhesveykppkkpfvKLKDCIELFTTKEKLGAEDPWYCPNCKEHQQATK 791
           ***************************************************************************************** PP
   S: 220  klklkklPevLilhLkRfsfseeqksrekinkkvefple.LdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvknekgk.W 306
           kl+l++lP+vL++hLkRfs+s+  ++r k+++ v+fp++ Ld+s+f+++p+ +   +++Y+Liav +H+G++++GHY+a++kn++++ W
   Q: 792  KLDLWSLPPVLVVHLKRFSYSR--YMRDKLDTLVDFPINdLDMSEFLINPNAG---PCRYNLIAVSNHYGGMGGGHYTAFAKNKDDGkW 875
           ******************9977..6999*********************9988...8**************************65555* PP
   S: 307  llfdDskVtevkeeevleetgstaYvlfYkrr 338
           ++fdDs+V++ +e+++++   + aYvlfY+r+
   Q: 876  YYFDDSSVSTASEDQIVS---KAAYVLFYQRQ 904
           ******************...*********96 PP

ULD/UDP/UBQ/UBQ_Other

   S: 12   eltlkvnpsdtVaeLKekiekklgip.peqqrLiyk.....GkiL.eddktLadyglkdgstihllekksg 75
           + t++++++dt+ ++ ++i+k ++ip + + rL++k      ++L ++d t++d gl++g+++++++k+++
   Q: 118  VVTRRFSKADTIDTIEKEIRKIFSIPdEKETRLWNKymsntFEPLnKPDSTIQDAGLYQGQVLVIEQKNED 188
           77899*********************999*****998875544569*********************9986 PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

YLVDSRWFKQ WKKYVGFDSW DKYQMGDQNV YPGPIDNSGL LKADGDAQSL KEHLIDELDY 60
ILLPTEGWNK LVSWYTLMEG QEPIARKVVE QGMFVKHCKV EVYLTELKLC ENGNMNNVVT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGTACCTAGT CGATAGTCGC TGGTTCAAAC AGTGGAAAAA ATATGTTGGC TTTGACAGTT 60
GGGACAAATA CCAGATGGGA GATCAAAATG TGTATCCTGG ACCCATTGAT AACTCTGGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR013792--RNA3'P_cycl/enolpyr_Trfase_a/b
IPR028135--Ub_USP-typ
IPR029071--Ubiquitin-rel_dom
IPR029346--USP_C
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS51283--DUSP
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF06337--DUSP
PF14836--Ubiquitin_3
PF00443--UCH
PF14533--USP7_C2

SMART

SM00695--DUSP

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0030509--P:BMP signaling pathway
GO:0035616--P:histone H2B conserved C-terminal lysine deubiquitination
GO:0035520--P:monoubiquitinated protein deubiquitination
GO:0060389--P:pathway-restricted SMAD protein phosphorylation
GO:0007179--P:transforming growth factor beta receptor signaling pathway
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000058	Aegilops tauschii	39.91	3.00e-119	422.00
IUUC-Aml-001852	Ailuropoda melanoleuca	99.05	0.00e+00	1843.00
IUUC-Apl-003249	Anas platyrhynchos	94.97	0.00e+00	1716.00
IUUC-Aca-004261	Anolis carolinensis	93.60	0.00e+00	1692.00
IUUC-Aly-005644	Arabidopsis lyrata	36.06	1.00e-134	474.00
IUUC-Ath-006782	Arabidopsis thaliana	35.74	2.00e-134	473.00
IUUC-Acl-008284	Aspergillus clavatus	35.27	2.00e-55	211.00
IUUC-Afl-008507	Aspergillus flavus	43.30	1.00e-53	205.00
IUUC-Aor-009949	Aspergillus oryzae	42.96	2.00e-52	201.00
IUUC-Ate-010323	Aspergillus terreus	43.64	7.00e-54	206.00
IUUC-Ame-010757	Astyanax mexicanus	79.98	0.00e+00	1261.00
IUUC-Bgr-012277	Blumeria graminis	42.40	2.00e-63	238.00
IUUC-Bta-013128	Bos taurus	95.59	0.00e+00	1796.00
IUUC-Bdi-014013	Brachypodium distachyon	36.60	7.00e-149	521.00
IUUC-Bol-015570	Brassica oleracea	37.90	2.00e-153	536.00
IUUC-Bra-017029	Brassica rapa	36.72	3.00e-138	485.00
IUUC-Cja-019222	Callithrix jacchus	99.37	0.00e+00	1837.00
IUUC-Cfa-020035	Canis familiaris	99.05	0.00e+00	1841.00
IUUC-Cpo-022071	Cavia porcellus	98.43	0.00e+00	1743.00
IUUC-Csa-023882	Chlorocebus sabaeus	99.79	0.00e+00	1843.00
IUUC-Cin-025292	Ciona intestinalis	45.09	0.00e+00	727.00
IUUC-Csv-026109	Ciona savignyi	47.29	6.00e-150	525.00
IUUC-Cne-026852	Cryptococcus neoformans	46.45	2.00e-71	264.00
IUUC-Cme-027338	Cyanidioschyzon merolae	56.36	4.00e-68	252.00
IUUC-Dno-029025	Dasypus novemcinctus	94.75	0.00e+00	1775.00
IUUC-Dor-030956	Dipodomys ordii	90.00	0.00e+00	1623.00
IUUC-Dse-031432	Dothistroma septosporum	40.43	4.00e-58	220.00
IUUC-Eca-034340	Equus caballus	99.26	0.00e+00	1837.00
IUUC-Eeu-034488	Erinaceus europaeus	88.79	0.00e+00	1204.00
IUUC-Fca-035552	Felis catus	95.69	0.00e+00	1791.00
IUUC-Fal-036618	Ficedula albicollis	94.86	0.00e+00	1709.00
IUUC-Gga-041146	Gallus gallus	94.03	0.00e+00	1700.00
IUUC-Gac-041679	Gasterosteus aculeatus	77.42	0.00e+00	1408.00
IUUC-Gma-043037	Glycine max	34.75	7.00e-134	471.00
IUUC-Hsa-046052	Homo sapiens	99.89	0.00e+00	1844.00
IUUC-Hvu-047108	Hordeum vulgare	40.24	6.00e-123	434.00
IUUC-Itr-048306	Ictidomys tridecemlineatus	95.60	0.00e+00	1793.00
IUUC-Kpa-049332	Komagataella pastoris	43.67	2.00e-63	237.00
IUUC-Lch-050107	Latimeria chalumnae	86.90	0.00e+00	1680.00
IUUC-Lpe-051185	Leersia perrieri	40.42	2.00e-125	443.00
IUUC-Loc-052105	Lepisosteus oculatus	83.73	0.00e+00	1455.00
IUUC-Lma-052981	Leptosphaeria maculans	36.72	5.00e-66	247.00
IUUC-Laf-053645	Loxodonta africana	98.43	0.00e+00	1825.00
IUUC-Mcc-055586	Macaca mulatta	99.89	0.00e+00	1844.00
IUUC-Meu-056764	Macropus eugenii	90.15	0.00e+00	1003.00
IUUC-Mla-058848	Melampsora laricipopulina	40.56	4.00e-67	250.00
IUUC-Mga-060162	Meleagris gallopavo	94.34	0.00e+00	1704.00
IUUC-Mvi-060324	Microbotryum violaceum	40.38	7.00e-72	266.00
IUUC-Mmr-061105	Microcebus murinus	99.26	0.00e+00	1836.00
IUUC-Mdo-062107	Monodelphis domestica	97.06	0.00e+00	1778.00
IUUC-Mmu-063662	Mus musculus	97.48	0.00e+00	1813.00
IUUC-Mac-065239	Musa acuminata	33.26	1.00e-128	454.00
IUUC-Mpu-065868	Mustela putorius furo	96.81	0.00e+00	1822.00
IUUC-Mlu-068000	Myotis lucifugus	91.91	0.00e+00	1673.00
IUUC-Nle-069874	Nomascus leucogenys	99.67	0.00e+00	1816.00
IUUC-Opr-071212	Ochotona princeps	93.20	0.00e+00	1717.00
IUUC-Ont-071834	Oreochromis niloticus	79.37	0.00e+00	1400.00
IUUC-Ocu-074573	Oryctolagus cuniculus	99.26	0.00e+00	1838.00
IUUC-Oba-075427	Oryza barthii	34.71	3.00e-131	462.00
IUUC-Obr-076416	Oryza brachyantha	39.75	6.00e-119	421.00
IUUC-Ogl-077583	Oryza glaberrima	40.36	6.00e-128	451.00
IUUC-Ogu-078422	Oryza glumaepatula	34.61	3.00e-131	462.00
IUUC-Oin-079300	Oryza indica	40.51	5.00e-129	455.00
IUUC-Olo-080315	Oryza longistaminata	36.19	1.00e-145	510.00
IUUC-Ome-081271	Oryza meridionalis	36.28	4.00e-147	515.00
IUUC-Oni-082834	Oryza nivara	34.82	5.00e-132	465.00
IUUC-Opu-083691	Oryza punctata	35.03	4.00e-144	505.00
IUUC-Oru-084820	Oryza rufipogon	34.61	2.00e-131	462.00
IUUC-Osa-086139	Oryza sativa	36.16	2.00e-146	513.00
IUUC-Oga-089022	Otolemur garnettii	95.27	0.00e+00	1791.00
IUUC-Oar-089767	Ovis aries	98.63	0.00e+00	1829.00
IUUC-Ptr-091319	Pan troglodytes	96.64	0.00e+00	1810.00
IUUC-Pan-091968	Papio anubis	99.79	0.00e+00	1843.00
IUUC-Psi-093849	Pelodiscus sinensis	93.40	0.00e+00	1707.00
IUUC-Pma-094533	Petromyzon marinus	59.75	0.00e+00	1073.00
IUUC-Pno-094890	Phaeosphaeria nodorum	36.39	3.00e-59	224.00
IUUC-Pfo-097110	Poecilia formosa	78.03	0.00e+00	1397.00
IUUC-Pab-098664	Pongo abelii	99.79	0.00e+00	1843.00
IUUC-Pop-099801	Populus trichocarpa	37.05	2.00e-148	520.00
IUUC-Pca-100359	Procavia capensis	80.83	0.00e+00	1332.00
IUUC-Ppe-101587	Prunus persica	36.98	5.00e-149	521.00
IUUC-Pva-102394	Pteropus vampyrus	97.27	0.00e+00	1791.00
IUUC-Pgr-103546	Puccinia graminis	29.75	2.00e-66	248.00
IUUC-Ptt-103847	Puccinia triticina	39.46	5.00e-60	226.00
IUUC-Pte-104102	Pyrenophora teres	35.50	7.00e-57	216.00
IUUC-Pyt-104812	Pyrenophora triticirepentis	39.43	2.00e-56	214.00
IUUC-Rno-105383	Rattus norvegicus	94.85	0.00e+00	1788.00
IUUC-Sce-106170	Saccharomyces cerevisiae	36.97	2.00e-60	228.00
IUUC-Sha-107393	Sarcophilus harrisii	97.17	0.00e+00	1783.00
IUUC-Sja-107752	Schizosaccharomyces japonicus	34.10	9.00e-81	295.00
IUUC-Ssl-108461	Sclerotinia sclerotiorum	30.56	1.00e-13	71.60
IUUC-Smo-109356	Selaginella moellendorffii	46.85	2.00e-79	290.00
IUUC-Sit-109948	Setaria italica	36.79	1.00e-139	490.00
IUUC-Sly-111726	Solanum lycopersicum	40.38	2.00e-90	327.00
IUUC-Stu-112671	Solanum tuberosum	36.44	5.00e-143	501.00
IUUC-Sar-113498	Sorex araneus	98.53	0.00e+00	1826.00
IUUC-Sbi-114874	Sorghum bicolor	36.52	3.00e-142	499.00
IUUC-Sre-115130	Sporisorium reilianum	43.87	2.00e-77	284.00
IUUC-Ssc-115285	Sus scrofa	99.37	0.00e+00	1844.00
IUUC-Tgu-116529	Taeniopygia guttata	94.76	0.00e+00	1715.00
IUUC-Tru-118298	Takifugu rubripes	78.59	0.00e+00	1410.00
IUUC-Tsy-119117	Tarsius syrichta	89.79	0.00e+00	1157.00
IUUC-Tni-120093	Tetraodon nigroviridis	76.09	0.00e+00	1355.00
IUUC-Tre-121888	Trichoderma reesei	42.09	2.00e-62	235.00
IUUC-Tvi-122422	Trichoderma virens	39.57	5.00e-57	216.00
IUUC-Tae-125295	Triticum aestivum	36.18	1.00e-145	510.00
IUUC-Tur-126149	Triticum urartu	39.50	6.00e-106	378.00
IUUC-Tbe-127672	Tupaia belangeri	97.34	0.00e+00	1216.00
IUUC-Ttr-128441	Tursiops truncatus	94.36	0.00e+00	1095.00
IUUC-Vda-129781	Verticillium dahliae	43.73	3.00e-65	244.00
IUUC-Vpa-130469	Vicugna pacos	98.84	0.00e+00	1826.00
IUUC-Vvi-131010	Vitis vinifera	37.92	8.00e-149	521.00
IUUC-Xtr-132729	Xenopus tropicalis	84.59	0.00e+00	1573.00
IUUC-Xma-133550	Xiphophorus maculatus	78.14	0.00e+00	1394.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence