iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
TRANSFAC	RAID2
Post-translational Modifications (PTMs)
dbPAF
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/Other	96.54	0.00e+00	3020.00	IUUC-Hsa-046897

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MIETMHCIFI TELQTFFRNL LKKNVLFFEP KIVHRQTYKS KLICKVLLCF FQQLLCDIGH 60
SEEKLGFNYE DIIICLRLAL LNEAKEVRAA GLRALRYLIQ DSSILQKVLK LKVDYLIARC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCCATCATGG AGGCCATGGG GAAGAAATGT CACCTGTTAG ATGAATCAGC AGTGTTGTCA 60
ACACAGTAGT GACCACTGGG AATGATGAAT AAGACATTAA CACCGTAGGA GGGAAATACA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR028268--Pianissimo_fam
IPR028267--Pianissimo_N
IPR029453--Rictor_IV
IPR029451--RICTOR_M
IPR029259--RICTOR_phospho
IPR029452--RICTOR_V

Pfam

PF14663--RasGEF_N_2
PF14666--RICTOR_M
PF14664--RICTOR_N
PF14665--RICTOR_phospho
PF14668--RICTOR_V

SMART

SM01307--RICTOR_M
SM01308--RICTOR_N
SM01309--RICTOR_phospho
SM01310--RICTOR_V

Gene Ontology

GO:0031932--C:TORC2 complex
GO:0008047--F:enzyme activator activity
GO:0043022--F:ribosome binding
GO:0031532--P:actin cytoskeleton reorganization
GO:0009790--P:embryo development
GO:0030010--P:establishment of cell polarity
GO:0030950--P:establishment or maintenance of actin cytoskeleton polarity
GO:0018105--P:peptidyl-serine phosphorylation
GO:0030838--P:positive regulation of actin filament polymerization
GO:0001938--P:positive regulation of endothelial cell proliferation
GO:0050731--P:positive regulation of peptidyl-tyrosine phosphorylation
GO:0051897--P:positive regulation of protein kinase B signaling
GO:0032008--P:positive regulation of TOR signaling
GO:0032956--P:regulation of actin cytoskeleton organization
GO:2000114--P:regulation of establishment of cell polarity
GO:0010468--P:regulation of gene expression
GO:0043087--P:regulation of GTPase activity
GO:0050727--P:regulation of inflammatory response
GO:0033135--P:regulation of peptidyl-serine phosphorylation
GO:0042325--P:regulation of phosphorylation
GO:0031929--P:TOR signaling

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-004111	Anas platyrhynchos	86.18	0.00e+00	1786.00
IUUC-Aca-004885	Anolis carolinensis	83.03	0.00e+00	2656.00
IUUC-Ago-007975	Ashbya gossypii	28.04	8.00e-43	169.00
IUUC-Afu-008889	Aspergillus fumigatus	29.94	5.00e-103	369.00
IUUC-Ang-009838	Aspergillus niger	29.18	1.00e-100	361.00
IUUC-Ate-010586	Aspergillus terreus	29.14	2.00e-99	357.00
IUUC-Bgr-012287	Blumeria graminis	29.01	2.00e-99	358.00
IUUC-Bta-013347	Bos taurus	96.66	0.00e+00	2986.00
IUUC-Bci-013718	Botrytis cinerea	30.50	9.00e-109	388.00
IUUC-Bol-016394	Brassica oleracea	29.67	2.50e-01	28.50
IUUC-Cja-019360	Callithrix jacchus	96.48	0.00e+00	3037.00
IUUC-Cpo-022258	Cavia porcellus	97.89	3.00e-136	477.00
IUUC-Cho-024748	Choloepus hoffmanni	89.94	0.00e+00	1305.00
IUUC-Cin-025491	Ciona intestinalis	40.00	6.00e-105	375.00
IUUC-Csv-025990	Ciona savignyi	37.96	3.00e-137	482.00
IUUC-Cgl-026666	Colletotrichum gloeosporioides	29.20	6.00e-100	359.00
IUUC-Cne-026882	Cryptococcus neoformans	30.61	2.00e-80	294.00
IUUC-Dre-027391	Danio rerio	84.69	0.00e+00	1666.00
IUUC-Dno-029612	Dasypus novemcinctus	92.61	0.00e+00	2863.00
IUUC-Dor-030974	Dipodomys ordii	95.11	0.00e+00	1375.00
IUUC-Ete-032905	Echinops telfairi	92.48	0.00e+00	2825.00
IUUC-Eca-033490	Equus caballus	93.32	0.00e+00	2895.00
IUUC-Eeu-035218	Erinaceus europaeus	84.27	0.00e+00	1354.00
IUUC-Fca-035568	Felis catus	95.39	0.00e+00	2942.00
IUUC-Fal-037265	Ficedula albicollis	85.91	0.00e+00	2729.00
IUUC-Fox-037847	Fusarium oxysporum	29.92	9.00e-97	348.00
IUUC-Fso-038392	Fusarium solani	29.07	9.00e-103	369.00
IUUC-Gmo-039569	Gadus morhua	73.39	0.00e+00	1616.00
IUUC-Ggr-039786	Gaeumannomyces graminis	29.03	8.00e-96	345.00
IUUC-Gga-040814	Gallus gallus	86.32	0.00e+00	2707.00
IUUC-Gac-042152	Gasterosteus aculeatus	65.14	0.00e+00	1982.00
IUUC-Hsa-046897	Homo sapiens	96.54	0.00e+00	3039.00
IUUC-Itr-047870	Ictidomys tridecemlineatus	94.47	0.00e+00	2912.00
IUUC-Kpa-049264	Komagataella pastoris	29.88	1.00e-50	195.00
IUUC-Lch-049566	Latimeria chalumnae	79.90	0.00e+00	2497.00
IUUC-Loc-052514	Lepisosteus oculatus	77.67	0.00e+00	2392.00
IUUC-Lma-053045	Leptosphaeria maculans	30.65	2.00e-85	311.00
IUUC-Laf-053388	Loxodonta africana	96.24	0.00e+00	3024.00
IUUC-Mcc-055195	Macaca mulatta	94.86	0.00e+00	2970.00
IUUC-Meu-056687	Macropus eugenii	92.04	2.00e-89	325.00
IUUC-Mor-056999	Magnaporthe oryzae	28.66	5.00e-99	356.00
IUUC-Mpo-057301	Magnaporthe poae	29.47	1.00e-100	362.00
IUUC-Mla-058853	Melampsora laricipopulina	27.31	2.00e-74	274.00
IUUC-Mga-059725	Meleagris gallopavo	75.64	0.00e+00	2128.00
IUUC-Mmr-060679	Microcebus murinus	96.78	0.00e+00	3018.00
IUUC-Mmu-063859	Mus musculus	97.21	0.00e+00	3002.00
IUUC-Mlu-067734	Myotis lucifugus	95.63	0.00e+00	2995.00
IUUC-Nfi-068380	Neosartorya fischeri	29.83	1.00e-101	365.00
IUUC-Ncr-068779	Neurospora crassa	28.94	2.00e-99	358.00
IUUC-Opr-071025	Ochotona princeps	86.07	0.00e+00	1930.00
IUUC-Ont-072104	Oreochromis niloticus	76.90	0.00e+00	1689.00
IUUC-Ocu-074388	Oryctolagus cuniculus	96.66	0.00e+00	3022.00
IUUC-Oru-084208	Oryza rufipogon	22.48	4.30e-02	32.30
IUUC-Ola-087503	Oryzias latipes	69.40	0.00e+00	2166.00
IUUC-Oar-089642	Ovis aries	96.90	0.00e+00	3001.00
IUUC-Ptr-090779	Pan troglodytes	96.42	0.00e+00	3055.00
IUUC-Pan-092099	Papio anubis	96.72	0.00e+00	3047.00
IUUC-Psi-093606	Pelodiscus sinensis	86.29	0.00e+00	2711.00
IUUC-Pno-094990	Phaeosphaeria nodorum	28.80	6.00e-86	313.00
IUUC-Pab-098429	Pongo abelii	95.45	0.00e+00	2990.00
IUUC-Pca-101045	Procavia capensis	91.98	0.00e+00	2942.00
IUUC-Pva-102675	Pteropus vampyrus	87.84	0.00e+00	1295.00
IUUC-Pgr-103341	Puccinia graminis	27.97	1.00e-42	169.00
IUUC-Ptt-103999	Puccinia triticina	28.99	6.00e-43	169.00
IUUC-Sce-106173	Saccharomyces cerevisiae	29.30	9.00e-43	169.00
IUUC-Sha-107121	Sarcophilus harrisii	89.87	0.00e+00	2852.00
IUUC-Sja-107806	Schizosaccharomyces japonicus	27.82	3.00e-78	287.00
IUUC-Spo-108187	Schizosaccharomyces pombe	27.89	3.00e-91	330.00
IUUC-Ssl-108665	Sclerotinia sclerotiorum	36.34	1.00e-64	242.00
IUUC-Sit-110556	Setaria italica	29.58	5.50e-01	30.00
IUUC-Sar-113499	Sorex araneus	86.70	0.00e+00	2546.00
IUUC-Sre-114992	Sporisorium reilianum	28.47	1.00e-95	345.00
IUUC-Ssc-115246	Sus scrofa	96.78	0.00e+00	2995.00
IUUC-Tgu-116455	Taeniopygia guttata	85.85	0.00e+00	2704.00
IUUC-Tru-118605	Takifugu rubripes	68.97	0.00e+00	2116.00
IUUC-Tsy-119061	Tarsius syrichta	90.10	0.00e+00	2773.00
IUUC-Tni-119726	Tetraodon nigroviridis	76.18	0.00e+00	1570.00
IUUC-Tre-121918	Trichoderma reesei	30.06	6.00e-100	359.00
IUUC-Tvi-122587	Trichoderma virens	29.73	1.00e-94	342.00
IUUC-Tbe-127960	Tupaia belangeri	92.55	0.00e+00	2281.00
IUUC-Ttr-128848	Tursiops truncatus	95.36	0.00e+00	2686.00
IUUC-Uma-129394	Ustilago maydis	28.97	2.00e-100	361.00
IUUC-Vda-129772	Verticillium dahliae	29.23	6.00e-94	339.00
IUUC-Vpa-130325	Vicugna pacos	93.90	0.00e+00	2828.00
IUUC-Xtr-132777	Xenopus tropicalis	78.61	0.00e+00	2426.00
IUUC-Xma-133798	Xiphophorus maculatus	69.28	0.00e+00	2159.00
IUUC-Yli-134450	Yarrowia lipolytica	28.25	4.00e-75	276.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence