iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tru-118739

UUCD1 version

UUC-TaR-01123

Ensembl Protein ID

ENSTRUP00000011266.1

UniProt Accession

H2SFT5; H2SFT5_TAKRU

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000004736.1	ENSTRUT00000011325.1	ENSTRUP00000011265.1
ENSTRUG00000004736.1	ENSTRUT00000011326.1	ENSTRUP00000011266.1
ENSTRUG00000004736.1	ENSTRUT00000011327.1	ENSTRUP00000011267.1
ENSTRUG00000004736.1	ENSTRUT00000011328.1	ENSTRUP00000011268.1
ENSTRUG00000004736.1	ENSTRUT00000011329.1	ENSTRUP00000011269.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	3.50e-115	386.1	620	1363

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsg 86
           tGl NlgNtC+mNSv+Q+Lsn++elr+++l+  ++ ++n +np ++ g+l+  ++ l+++lwk++++a++p++l+++++++a++f+g
   Q: 620  TGLVNLGNTCFMNSVIQSLSNTRELRDYFLDrGFEAEINCSNPLGTGGRLAIGFAVLLRALWKGTHHAFQPSKLKAIVASKASQFTG 706
           7******************************889***************************************************** PP
   S: 87   yeqqDaqEflaflldqleeelkkeknkpkeeeeeed...kselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfl 170
           y+q+DaqEf+aflld+l+e+l++ +nkp++e+ ++d   ++   dea++++k++n+s+i+dlFqgq+ks+++c+ c +vs +++pfl
   Q: 707  YAQHDAQEFMAFLLDGLHEDLNRIQNKPYTETVDSDgrlDEVVADEAWQRHKMRNDSFIVDLFQGQFKSKLVCPMCSKVSITFDPFL 793
           ********************************99982222344555***************************************** PP
   S: 171  dlslpvpgkeetkke........................................................................ 185
           +l++p+p+k++                                                                            
   Q: 794  YLPVPLPQKQKVLSVyyfakephkkpikfsvsvskensrtaevlesisrnvrvkpenlrlaevgknrfqrmflpshsldtvtstdml 880
           **********76444************************************************************************ PP
   S: 186  ....................................................................................... 185
                                                                                                  
   Q: 881  fcfellskemakervvflrvqqklqvpnipiskcaacqkppvseedklkrctrcyrvgycnqvcqrthwpnhkslcrpntenvglpf 967
           *************************************************************************************** PP
   S: 186  ....................................................................................... 185
                                                                                                  
   Q: 968  lvsvpesrlsyarltqllegysrfsvdvfqppfhsgrtspetsragdlaplpvschetrgssdealcssaagsgdleldspslqpad 1054
           *************************************************************************************** PP
   S: 186  ....................................................................................... 185
                                                                                                  
   Q: 1055 qeecaqasapvvgvvdslsslqtstthtsdlgffehfssvsccsfdpnaeketscektarpeaavtgyqhpseltsahasqffisll 1141
           *************************************************************************************** PP
   S: 186  ................................................................slqdcLesftkeeelegenkyyc 208
                                                                           sl++cL+ ftk+e l  e+++yc
   Q: 1142 dsnnkeqrldekedawanlpedatlelvwknnerlkeyvlvsskdldyeedpsslsetaraghfSLEQCLNLFTKPEVLAPEEAWYC 1228
           *************************************************************************************** PP
   S: 209  ekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.LdlspfctspeekqkekkkYeLiavvvHsGslssGH 294
           +kc++++ea+k+l l++lP+vLi++LkRfsf++  +++ kin+ v+fp++ Ldls+fc+  +++ +++ +Y+L+av++H+G++ +GH
   Q: 1229 PKCQQHREASKQLLLWRLPNVLIIQLKRFSFRSFIWRD-KINDMVDFPIRnLDLSKFCIGMKDEMQQPPIYDLYAVINHYGGMIGGH 1314
           **********************************8886.************************************************ PP
   S: 295  Yvayvknekgk........WllfdDskVtevkeeevleetgstaYvlfYkrr 338
           Y+ay++  ++k        W lfdDs+Vt v+e++v++   + aYvlfY+rr
   Q: 1315 YTAYARLPSDKnsqrsdvgWRLFDDSTVTMVDESQVVT---RYAYVLFYRRR 1363
           ******9444444567788*******************...********996 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

SHQRRGNGRE AGSDLSSCTS KKKQKDRANQ ESREAKRTVA VVDGVTAEIK KDVFVDWKQN 60
VNEVTVRLRC GDGIQRKEDV DTSFTDKSCH VSFPDGRHWS CLLQEEIEAS CSRVLYKEKG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGAATAAGGC CACCTGAATC ATACCATACT ATCCTCTACG GAGTCGGGTC GTGGGGGCAG 60
CAGCCTAAGC AGAGAGGCCC AGACTTCCCT CTCCCCTGCT ACTTCTTCCA GCTGGTCCGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR007052--CS_dom
IPR008978--HSP20-like_chaperone
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR002893--Znf_MYND

PROSITE

PS51203--CS
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS01360--ZF_MYND_1
PS50865--ZF_MYND_2

Pfam

PF04969--CS
PF00443--UCH
PF01753--zf-MYND

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0021551--P:central nervous system morphogenesis
GO:0016579--P:protein deubiquitination
GO:0030433--P:ubiquitin-dependent ERAD pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001999	Ailuropoda melanoleuca	65.63	0.00e+00	1366.00
IUUC-Apl-003368	Anas platyrhynchos	68.54	0.00e+00	1383.00
IUUC-Aca-004267	Anolis carolinensis	68.08	0.00e+00	1367.00
IUUC-Ame-010970	Astyanax mexicanus	76.37	0.00e+00	1488.00
IUUC-Bta-012905	Bos taurus	65.57	0.00e+00	1337.00
IUUC-Cel-018257	Caenorhabditis elegans	43.66	1.00e-93	338.00
IUUC-Cja-018789	Callithrix jacchus	69.56	0.00e+00	1357.00
IUUC-Cfa-021004	Canis familiaris	67.81	0.00e+00	1340.00
IUUC-Cpo-021529	Cavia porcellus	69.07	0.00e+00	1313.00
IUUC-Csa-024035	Chlorocebus sabaeus	67.33	0.00e+00	1374.00
IUUC-Cho-025036	Choloepus hoffmanni	69.53	1.00e-176	614.00
IUUC-Cin-025451	Ciona intestinalis	42.22	2.00e-86	314.00
IUUC-Csv-025931	Ciona savignyi	45.89	6.00e-55	208.00
IUUC-Dre-028556	Danio rerio	60.53	0.00e+00	1529.00
IUUC-Dno-029240	Dasypus novemcinctus	66.28	0.00e+00	1254.00
IUUC-Dor-030495	Dipodomys ordii	67.84	0.00e+00	856.00
IUUC-Ete-032741	Echinops telfairi	67.31	0.00e+00	1327.00
IUUC-Eca-033661	Equus caballus	67.88	0.00e+00	1350.00
IUUC-Eeu-034648	Erinaceus europaeus	70.64	7.00e-160	558.00
IUUC-Fca-035646	Felis catus	65.84	0.00e+00	1337.00
IUUC-Fal-037094	Ficedula albicollis	68.16	0.00e+00	1402.00
IUUC-Gmo-038869	Gadus morhua	76.32	0.00e+00	948.00
IUUC-Gga-041170	Gallus gallus	69.71	0.00e+00	1389.00
IUUC-Gac-041901	Gasterosteus aculeatus	80.49	0.00e+00	1592.00
IUUC-Ggo-044708	Gorilla gorilla	68.59	0.00e+00	1348.00
IUUC-Hsa-046791	Homo sapiens	69.46	0.00e+00	1348.00
IUUC-Itr-048892	Ictidomys tridecemlineatus	69.62	0.00e+00	1287.00
IUUC-Lch-050456	Latimeria chalumnae	65.53	0.00e+00	1061.00
IUUC-Loc-052861	Lepisosteus oculatus	61.61	0.00e+00	1233.00
IUUC-Laf-053788	Loxodonta africana	69.68	0.00e+00	1322.00
IUUC-Mcc-055693	Macaca mulatta	67.21	0.00e+00	1367.00
IUUC-Meu-055921	Macropus eugenii	69.15	0.00e+00	1162.00
IUUC-Mga-059879	Meleagris gallopavo	70.03	0.00e+00	1382.00
IUUC-Mmr-060802	Microcebus murinus	69.50	0.00e+00	1347.00
IUUC-Mdo-061856	Monodelphis domestica	70.80	0.00e+00	1316.00
IUUC-Mmu-063874	Mus musculus	68.46	0.00e+00	1343.00
IUUC-Mpu-066166	Mustela putorius furo	66.54	0.00e+00	1337.00
IUUC-Nle-070161	Nomascus leucogenys	69.66	0.00e+00	1352.00
IUUC-Opr-071015	Ochotona princeps	69.36	0.00e+00	1316.00
IUUC-Ont-072308	Oreochromis niloticus	72.53	0.00e+00	2030.00
IUUC-Oan-072723	Ornithorhynchus anatinus	67.30	0.00e+00	1314.00
IUUC-Ocu-073938	Oryctolagus cuniculus	67.24	0.00e+00	1343.00
IUUC-Ola-086375	Oryzias latipes	80.88	0.00e+00	1669.00
IUUC-Oga-088297	Otolemur garnettii	69.46	0.00e+00	1334.00
IUUC-Oar-089675	Ovis aries	62.81	0.00e+00	1194.00
IUUC-Ptr-091621	Pan troglodytes	69.36	0.00e+00	1347.00
IUUC-Pan-092118	Papio anubis	67.72	0.00e+00	1373.00
IUUC-Pma-094154	Petromyzon marinus	50.00	9.00e-112	397.00
IUUC-Pfo-097246	Poecilia formosa	71.55	0.00e+00	1844.00
IUUC-Pab-098551	Pongo abelii	68.95	0.00e+00	1335.00
IUUC-Pca-100158	Procavia capensis	66.70	0.00e+00	1260.00
IUUC-Pva-103160	Pteropus vampyrus	69.59	0.00e+00	1304.00
IUUC-Rno-105355	Rattus norvegicus	69.22	0.00e+00	1322.00
IUUC-Sha-107057	Sarcophilus harrisii	68.56	0.00e+00	1357.00
IUUC-Sar-113011	Sorex araneus	62.47	0.00e+00	969.00
IUUC-Ssc-115761	Sus scrofa	67.62	0.00e+00	1342.00
IUUC-Tgu-116956	Taeniopygia guttata	61.32	0.00e+00	752.00
IUUC-Tsy-118827	Tarsius syrichta	75.65	0.00e+00	667.00
IUUC-Tni-119921	Tetraodon nigroviridis	87.48	0.00e+00	1779.00
IUUC-Tbe-128017	Tupaia belangeri	67.38	0.00e+00	1291.00
IUUC-Ttr-128869	Tursiops truncatus	67.79	0.00e+00	1309.00
IUUC-Vpa-130427	Vicugna pacos	61.59	2.00e-176	613.00
IUUC-Xtr-132734	Xenopus tropicalis	69.48	0.00e+00	1349.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence