iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ola-086953

Ensembl Protein ID

ENSORLP00000020250.1

UniProt Accession

H2MNE7; H2MNE7_ORYLA

Genbank Protein ID

ENSORLP00000020250

Protein Name

Tyrosine-protein kinase

Genbank Nucleotide ID

BAAF04080690

Gene Name

src; LOC101164480

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSORLG00000016183.1	ENSORLT00000020251.1	ENSORLP00000020250.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	7.50e-12	45.3	88	148

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlvi....ekeeqdegWlkgvkelegkrGlfPenFvek 61
           ++ +lydye+ +  +L+++kG+ ++++    + ++ +++W+ + + ++g +G +P+n+v+ 
   Q: 88   TFVALYDYESRTASDLSFRKGERLQIVnntrKVNCREGDWWLARSLATGESGYIPSNYVAP 148
           5789***********************7665556889*********************975 PP

Organism

Oryzias latipes

Protein Sequence
(Fasta)

MGATKSKPKD VGQRTRSLDG NPSSGGGAGS HHLNSGQQSL TPNRNPTADT GLNNQSAASN 60
AEMTLFGGVD NNIVSSSTRI TLAGGVTTFV ALYDYESRTA SDLSFRKGER LQIVNNTRKV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGGGCAA CCAAGAGTAA GCCCAAGGAT GTCGGCCAGC GAACCCGCAG CCTCGATGGT 60
AACCCCAGCT CTGGGGGAGG GGCTGGCAGC CATCACCTCA ATTCTGGTCA GCAGTCCCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
GO:0048920--P:posterior lateral line neuromast primordium migration
GO:0043114--P:regulation of vascular permeability
GO:0001878--P:response to yeast

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aly-005712	Arabidopsis lyrata	33.91	7.00e-21	95.90
IUUC-Ath-007146	Arabidopsis thaliana	34.13	9.00e-25	108.00
IUUC-Bol-016049	Brassica oleracea	33.62	4.00e-19	90.10
IUUC-Bra-017486	Brassica rapa	33.08	6.00e-23	102.00
IUUC-Dre-028491	Danio rerio	86.24	0.00e+00	934.00
IUUC-Ete-033170	Echinops telfairi	88.43	0.00e+00	851.00
IUUC-Eca-033970	Equus caballus	79.45	0.00e+00	876.00
IUUC-Fal-036785	Ficedula albicollis	82.20	0.00e+00	917.00
IUUC-Gac-042332	Gasterosteus aculeatus	91.34	0.00e+00	1004.00
IUUC-Gma-043938	Glycine max	32.56	2.00e-23	104.00
IUUC-Lch-049892	Latimeria chalumnae	81.95	0.00e+00	915.00
IUUC-Loc-052812	Lepisosteus oculatus	87.11	0.00e+00	958.00
IUUC-Laf-053977	Loxodonta africana	82.42	0.00e+00	924.00
IUUC-Mga-060135	Meleagris gallopavo	81.68	0.00e+00	912.00
IUUC-Ont-072666	Oreochromis niloticus	91.90	0.00e+00	967.00
IUUC-Pop-099554	Populus trichocarpa	31.40	1.00e-24	108.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence