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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Hsa-046395
UUCD1 version UUC-HoS-00143
Ensembl Protein ID ENSP00000304670.8
UniProt Accession Q5M7Z0; Q8N7D0; Q96IZ9; Q9Y686; RNFT1_HUMAN
Genbank Protein ID AAD43009.1; EAW94381.1; AAH88365.2; BAC05364.1
Protein Name RING finger and transmembrane domain-containing protein 1; Protein PTD016
Genbank Nucleotide ID AF100745; AC004686; BC006971; AK098649
Gene Name RNFT1; PTD016
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000189050.15 ENST00000305783.12 ENSP00000304670.8
ENSG00000189050.15 ENST00000482446.5 ENSP00000436144.1
ENSG00000189050.15 ENST00000466544.5 ENSP00000436533.1
ENSG00000189050.15 ENST00000484257.1 ENSP00000436909.1
ENSG00000189050.15 ENST00000589113.1 ENSP00000464987.1
Annotation
Cancer Mutation
TCGAICGCCOSMICCGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressTCGAICGC
COSMICHPM
DNA & RNA Element
UTRdbAREsitecircBaseCircNet
miRTarBasemicroRNATRANSFACTargetScan
miRNAMapSomamiRmiRcodeRAID2
Protein-protein Interaction
IIDiRefIndexPINAHINT
MenthaInWeb_IM
Disease-associated Information
GWASdbOMIM
Post-translational Modifications (PTMs)
CPLMdbPAFPhosphositePlusdbPTM
BioGRIDmUbiSiDa
DNA Methylation
TCGAICGC
Protein Expression/Proteomics
THPAHPMGPMDB
Status Reviewed
Details
Family Domain References (PMIDs)
E3 activity/RING/RING RING 19690564
Classification
Family E-value Score Start End
E3 activity/RING/RING 2.90e-06 29.4 375 413
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/RING
   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C+iC+ +f++ p++l C+H+f+++C   w       ++e +CPlCr
   Q: 375  CSICQAEFQK-PILLICQHIFCEECMTLW------FNREKTCPLCR 413
           **********.999***************......**********8 PP
   
Organism Homo sapiens
Protein Sequence
(Fasta)
MPLFLLSLPT PPSASGHERR QRPEAKTSGS EKKYLRAMQA NRSQLHSPPG TGSSEDASTP 60
QCVHTRLTGE GSCPHSGDVH IQINSIPKEC AENASSRNIR SGVHSCAHGC VHSRLRGHSH 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Hsa-046395|E3,RING|Homo sapiens
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CCGGGGAGCG CGCGCGCCGC CGCCGTTGCC GCCGGGCTGA GAGAAGAGCT TGCGGGGTTT 60
GCGGTTGATG GCCCCGACTG AAGGGCTGGA GGCGGTGTAT GCCGCTGTTC TTGCTGTCGC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Hsa-046395|E3,RING|Homo sapiens
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2
SMART

SM00184--RING
Gene Ontology

GO:0016021--C:integral component of membrane
GO:0008270--F:zinc ion binding
KEGG hsa:51136
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001586 Ailuropoda melanoleuca 88.46 0.00e+00 707.00
IUUC-Apl-003875 Anas platyrhynchos 72.43 1.00e-138 486.00
IUUC-Aca-004325 Anolis carolinensis 61.85 5.00e-126 444.00
IUUC-Ame-010748 Astyanax mexicanus 56.59 5.00e-93 334.00
IUUC-Bta-013167 Bos taurus 87.07 0.00e+00 716.00
IUUC-Cja-019669 Callithrix jacchus 95.23 0.00e+00 749.00
IUUC-Cfa-020610 Canis familiaris 90.95 0.00e+00 718.00
IUUC-Cpo-021979 Cavia porcellus 88.76 0.00e+00 652.00
IUUC-Csa-023752 Chlorocebus sabaeus 97.37 0.00e+00 814.00
IUUC-Cho-024880 Choloepus hoffmanni 80.00 0.00e+00 635.00
IUUC-Dre-028522 Danio rerio 57.88 1.00e-89 323.00
IUUC-Dno-029312 Dasypus novemcinctus 90.21 0.00e+00 675.00
IUUC-Dor-030524 Dipodomys ordii 81.29 3.00e-134 471.00
IUUC-Ete-032456 Echinops telfairi 78.50 2.00e-173 601.00
IUUC-Eeu-034649 Erinaceus europaeus 84.54 3.00e-89 322.00
IUUC-Fca-036321 Felis catus 86.57 0.00e+00 706.00
IUUC-Fal-036873 Ficedula albicollis 70.32 1.00e-138 486.00
IUUC-Gmo-038501 Gadus morhua 44.84 2.00e-81 296.00
IUUC-Gga-040583 Gallus gallus 65.33 9.00e-126 443.00
IUUC-Gac-042530 Gasterosteus aculeatus 55.19 2.00e-86 312.00
IUUC-Ggo-045577 Gorilla gorilla 95.49 0.00e+00 801.00
IUUC-Itr-048888 Ictidomys tridecemlineatus 90.95 0.00e+00 719.00
IUUC-Lch-049516 Latimeria chalumnae 56.64 9.00e-126 443.00
IUUC-Loc-052692 Lepisosteus oculatus 52.28 8.00e-97 347.00
IUUC-Laf-054478 Loxodonta africana 92.48 0.00e+00 728.00
IUUC-Mcc-055064 Macaca mulatta 96.82 0.00e+00 698.00
IUUC-Meu-056056 Macropus eugenii 66.99 1.00e-138 486.00
IUUC-Mga-059908 Meleagris gallopavo 79.84 2.00e-104 372.00
IUUC-Mdo-063071 Monodelphis domestica 79.43 0.00e+00 636.00
IUUC-Mmu-063446 Mus musculus 85.43 0.00e+00 630.00
IUUC-Mpu-065810 Mustela putorius furo 90.00 0.00e+00 634.00
IUUC-Nle-069009 Nomascus leucogenys 95.48 0.00e+00 798.00
IUUC-Ont-071863 Oreochromis niloticus 54.19 4.00e-84 305.00
IUUC-Oan-073490 Ornithorhynchus anatinus 79.20 2.00e-174 605.00
IUUC-Ocu-074346 Oryctolagus cuniculus 89.47 0.00e+00 687.00
IUUC-Ola-086809 Oryzias latipes 54.79 2.00e-81 296.00
IUUC-Oga-087950 Otolemur garnettii 89.81 0.00e+00 707.00
IUUC-Oar-089816 Ovis aries 88.48 0.00e+00 730.00
IUUC-Ptr-090736 Pan troglodytes 99.76 0.00e+00 834.00
IUUC-Pan-091961 Papio anubis 96.62 2.00e-116 411.00
IUUC-Psi-093766 Pelodiscus sinensis 80.19 4.00e-135 473.00
IUUC-Pfo-097090 Poecilia formosa 56.23 7.00e-78 284.00
IUUC-Pab-098474 Pongo abelii 98.39 0.00e+00 844.00
IUUC-Pca-100864 Procavia capensis 81.89 2.00e-123 435.00
IUUC-Rno-105126 Rattus norvegicus 84.42 0.00e+00 632.00
IUUC-Sha-107537 Sarcophilus harrisii 79.75 0.00e+00 634.00
IUUC-Sar-113494 Sorex araneus 79.27 4.00e-64 238.00
IUUC-Ssc-116039 Sus scrofa 85.71 1.00e-170 592.00
IUUC-Tgu-117409 Taeniopygia guttata 81.82 3.00e-129 454.00
IUUC-Tru-117926 Takifugu rubripes 49.06 2.00e-80 292.00
IUUC-Tsy-118995 Tarsius syrichta 89.65 0.00e+00 720.00
IUUC-Tni-120361 Tetraodon nigroviridis 47.65 6.00e-88 317.00
IUUC-Tbe-128158 Tupaia belangeri 71.11 1.00e-140 492.00
IUUC-Ttr-128496 Tursiops truncatus 86.21 0.00e+00 715.00
IUUC-Vpa-130045 Vicugna pacos 68.91 1.00e-86 313.00
IUUC-Xtr-132923 Xenopus tropicalis 56.90 2.00e-114 405.00
Created Date 25-Jun-2017

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