iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oga-088337

Ensembl Protein ID

ENSOGAP00000004978.2

UniProt Accession

H0WSB9; H0WSB9_OTOGA

Genbank Protein ID

ENSOGAP00000004978

Protein Name

Protein kinase C

Genbank Nucleotide ID

AAQR03114433

Gene Name

PRKCI

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000005563.2	ENSOGAT00000005570.2	ENSOGAP00000004978.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
ULD/UDP/UFD/PB1	8.40e-22	77.2	36	117

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

ULD/UDP/UFD/PB1

   S: 1    tvrvkvsykgeirsfaldlekpgkfedLlkavrtltelkn.sevalkYeDedGDlvtlksDedldkavslla.skksllrlliq 82
           +vrvk++y+g+i  + +++e++++fe L+++vr++++++n + +++k+ De+GD +t++s+ +l++a++l++ +k+s l ++++
   Q: 36   QVRVKAYYRGDI--MITHFEPSISFEGLCSEVRDMCSFDNdQLFTMKWIDEEGDPCTVSSQLELEEAFRLYElNKDSELLIHVF 117
           69**********..88******************************************************************98 PP

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

RAPRAPGSGE MPTQRDSSTM AHTVAGGGGG GDHSHQVRVK AYYRGDIMIT HFEPSISFEG 60
LCSEVRDMCS FDNDQLFTMK WIDEEGDPCT VSSQLELEEA FRLYELNKDS ELLIHVFPCV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGCGCCCCTC GCGCTCCCGG GAGCGGGGAG ATGCCGACCC AGAGGGACAG CAGCACCATG 60
GCCCACACGG TCGCGGGCGG CGGCGGCGGC GGGGACCACT CGCACCAGGT CCGGGTGAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0479--Metal-binding
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR000961--AGC-kinase_C
IPR020454--DAG/PE-bd
IPR011009--Kinase-like_dom
IPR000270--PB1_dom
IPR002219--PE/DAG-bd
IPR012233--PKC
IPR017892--Pkinase_C
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS

PROSITE

PS51285--AGC_KINASE_CTER
PS51745--PB1
PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00479--ZF_DAG_PE_1
PS50081--ZF_DAG_PE_2

Pfam

PF00130--C1_1
PF00564--PB1
PF00069--Pkinase
PF00433--Pkinase_C

PRINTS

PR00008--DAGPEDOMAIN

SMART

SM00109--C1
SM00666--PB1
SM00133--S_TK_X

Gene Ontology

GO:0016324--C:apical plasma membrane
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0045171--C:intercellular bridge
GO:0015630--C:microtubule cytoskeleton
GO:0005634--C:nucleus
GO:0043220--C:Schmidt-Lanterman incisure
GO:0005524--F:ATP binding
GO:0046872--F:metal ion binding
GO:0005543--F:phospholipid binding
GO:0004697--F:protein kinase C activity
GO:0007015--P:actin filament organization
GO:0045216--P:cell-cell junction organization
GO:0032869--P:cellular response to insulin stimulus
GO:0035089--P:establishment of apical/basal cell polarity
GO:0042462--P:eye photoreceptor cell development
GO:0035556--P:intracellular signal transduction
GO:0034351--P:negative regulation of glial cell apoptotic process
GO:0043524--P:negative regulation of neuron apoptotic process
GO:0018105--P:peptidyl-serine phosphorylation
GO:2000353--P:positive regulation of endothelial cell apoptotic process
GO:0090004--P:positive regulation of establishment of protein localization to plasma membrane
GO:0060252--P:positive regulation of glial cell proliferation
GO:0046326--P:positive regulation of glucose import
GO:0010976--P:positive regulation of neuron projection development
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001764	Ailuropoda melanoleuca	89.94	0.00e+00	941.00
IUUC-Apl-003711	Anas platyrhynchos	88.07	0.00e+00	989.00
IUUC-Aca-005142	Anolis carolinensis	87.41	0.00e+00	1006.00
IUUC-Ame-010977	Astyanax mexicanus	80.76	0.00e+00	908.00
IUUC-Bta-013414	Bos taurus	89.95	0.00e+00	1075.00
IUUC-Cel-018340	Caenorhabditis elegans	53.04	4.00e-176	611.00
IUUC-Cja-019802	Callithrix jacchus	90.64	0.00e+00	1027.00
IUUC-Cfa-021236	Canis familiaris	89.57	0.00e+00	1040.00
IUUC-Cpo-022127	Cavia porcellus	88.77	0.00e+00	985.00
IUUC-Csa-023332	Chlorocebus sabaeus	89.34	0.00e+00	860.00
IUUC-Cho-025054	Choloepus hoffmanni	61.17	1.00e-97	350.00
IUUC-Cin-025740	Ciona intestinalis	54.08	3.00e-176	611.00
IUUC-Csv-026145	Ciona savignyi	54.73	9.00e-168	583.00
IUUC-Dre-028444	Danio rerio	81.26	0.00e+00	929.00
IUUC-Dno-029228	Dasypus novemcinctus	86.71	1.00e-157	548.00
IUUC-Dme-031630	Drosophila melanogaster	60.23	0.00e+00	701.00
IUUC-Ete-032633	Echinops telfairi	64.19	3.00e-156	545.00
IUUC-Eca-033572	Equus caballus	90.67	0.00e+00	1025.00
IUUC-Eeu-035110	Erinaceus europaeus	89.90	0.00e+00	1050.00
IUUC-Fca-035559	Felis catus	90.38	0.00e+00	1074.00
IUUC-Fal-036953	Ficedula albicollis	88.56	0.00e+00	997.00
IUUC-Gmo-039334	Gadus morhua	80.76	0.00e+00	948.00
IUUC-Gga-040223	Gallus gallus	86.94	0.00e+00	1031.00
IUUC-Gac-042113	Gasterosteus aculeatus	80.93	0.00e+00	948.00
IUUC-Ggo-044520	Gorilla gorilla	83.98	0.00e+00	951.00
IUUC-Hsa-046991	Homo sapiens	90.55	0.00e+00	1077.00
IUUC-Lch-050263	Latimeria chalumnae	84.31	0.00e+00	1001.00
IUUC-Loc-052221	Lepisosteus oculatus	82.42	0.00e+00	941.00
IUUC-Laf-053591	Loxodonta africana	90.22	0.00e+00	1075.00
IUUC-Mcc-055118	Macaca mulatta	88.72	0.00e+00	1038.00
IUUC-Mga-059886	Meleagris gallopavo	88.07	0.00e+00	991.00
IUUC-Mmr-060926	Microcebus murinus	90.55	0.00e+00	1076.00
IUUC-Mdo-062698	Monodelphis domestica	86.25	0.00e+00	1021.00
IUUC-Mmu-063689	Mus musculus	90.71	0.00e+00	1071.00
IUUC-Mpu-066630	Mustela putorius furo	90.72	0.00e+00	1053.00
IUUC-Mlu-067416	Myotis lucifugus	86.61	0.00e+00	1003.00
IUUC-Nle-069811	Nomascus leucogenys	90.38	0.00e+00	1074.00
IUUC-Opr-070466	Ochotona princeps	76.77	0.00e+00	645.00
IUUC-Ont-072278	Oreochromis niloticus	79.83	0.00e+00	891.00
IUUC-Oan-073651	Ornithorhynchus anatinus	87.23	0.00e+00	644.00
IUUC-Ocu-074383	Oryctolagus cuniculus	90.71	0.00e+00	1076.00
IUUC-Ola-087283	Oryzias latipes	73.94	0.00e+00	696.00
IUUC-Oar-089954	Ovis aries	90.69	0.00e+00	1029.00
IUUC-Ptr-091673	Pan troglodytes	90.55	0.00e+00	1077.00
IUUC-Pan-092494	Papio anubis	89.76	0.00e+00	1080.00
IUUC-Psi-094044	Pelodiscus sinensis	85.97	0.00e+00	1017.00
IUUC-Pfo-096661	Poecilia formosa	79.44	0.00e+00	905.00
IUUC-Pab-097659	Pongo abelii	90.12	0.00e+00	1077.00
IUUC-Pca-101107	Procavia capensis	87.41	0.00e+00	702.00
IUUC-Rno-105790	Rattus norvegicus	90.88	0.00e+00	1077.00
IUUC-Sha-106895	Sarcophilus harrisii	88.81	0.00e+00	987.00
IUUC-Sar-113513	Sorex araneus	95.95	2.00e-178	619.00
IUUC-Ssc-115835	Sus scrofa	89.58	0.00e+00	935.00
IUUC-Tgu-116874	Taeniopygia guttata	86.66	0.00e+00	1028.00
IUUC-Tru-117823	Takifugu rubripes	81.02	0.00e+00	918.00
IUUC-Tsy-119154	Tarsius syrichta	90.49	0.00e+00	1023.00
IUUC-Tni-119968	Tetraodon nigroviridis	79.06	0.00e+00	904.00
IUUC-Tbe-127238	Tupaia belangeri	69.66	0.00e+00	640.00
IUUC-Ttr-129208	Tursiops truncatus	90.22	0.00e+00	1074.00
IUUC-Vpa-130363	Vicugna pacos	79.67	0.00e+00	901.00
IUUC-Xtr-132652	Xenopus tropicalis	79.67	0.00e+00	952.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence