iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cpo-022085

Ensembl Protein ID

ENSCPOP00000020823.1

UniProt Accession

H0WCV2; H0WCV2_CAVPO

Genbank Protein ID

ENSCPOP00000020823

Protein Name

Inhibitor of growth protein

Genbank Nucleotide ID

AAKN02019244

Gene Name

ING5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000022917.1	ENSCPOT00000020881.1	ENSCPOP00000020823.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	2.50e-09	37.2	183	230

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCrs 53
           ++C +C++ + +e  ++ C++  C  ewfH+aC+ l+   ++p+ + w+Cp+C +
   Q: 183  TYC-LCHQVSYGE--MIGCDNpdCPiEWFHFACVDLT---TKPKGK-WFCPRCVQ 230
           69*.*******99..*********99***********...999997.******87 PP

Organism

Cavia porcellus

Protein Sequence
(Fasta)

MYLEHYLDSI ENLPCELQRN FQLMRELDQR TEDKKAEIDM LAAEYISTVK TLSPDQRVEH 60
LQKIQSAYSK CKEYSDDKVQ LAMQTYEMVD KHIRRLDADL ARFEADLKDK MDGSDFESSG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTACTTGG AGCACTACCT GGACAGTAAG CGCCGCCACT GTGTCGCTGA CCGCGCCGCA 60
CGCGCCGCCT CCAGCCGTCC CCGCACGCGC AGCCCGCGTG TGGGCCTCGG GGACCCGGCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028638--ING5
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF12998--ING

SMART

SM01408--ING
SM00249--PHD

Gene Ontology

GO:0070776--C:MOZ/MORF histone acetyltransferase complex
GO:0003682--F:chromatin binding
GO:0008270--F:zinc ion binding
GO:0016573--P:histone acetylation
GO:0008285--P:negative regulation of cell proliferation
GO:2001235--P:positive regulation of apoptotic signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002381	Ailuropoda melanoleuca	96.49	4.00e-111	393.00
IUUC-Atr-002906	Amborella trichopoda	33.74	3.00e-34	137.00
IUUC-Apl-003516	Anas platyrhynchos	90.20	4.00e-98	350.00
IUUC-Aca-005009	Anolis carolinensis	85.53	3.00e-110	390.00
IUUC-Ame-011879	Astyanax mexicanus	75.11	6.00e-102	363.00
IUUC-Bta-012590	Bos taurus	96.04	5.00e-115	406.00
IUUC-Cja-019518	Callithrix jacchus	96.61	8.00e-121	425.00
IUUC-Cfa-020620	Canis familiaris	98.31	7.00e-133	466.00
IUUC-Csa-023421	Chlorocebus sabaeus	97.88	5.00e-118	416.00
IUUC-Dre-027588	Danio rerio	76.89	1.00e-102	365.00
IUUC-Eca-033493	Equus caballus	96.92	5.00e-120	422.00
IUUC-Fca-035635	Felis catus	95.45	4.00e-56	211.00
IUUC-Fal-036998	Ficedula albicollis	90.00	8.00e-113	399.00
IUUC-Fox-037925	Fusarium oxysporum	59.62	2.00e-19	90.10
IUUC-Gmo-039035	Gadus morhua	75.95	6.00e-100	356.00
IUUC-Gga-040578	Gallus gallus	91.10	1.00e-119	421.00
IUUC-Gac-042172	Gasterosteus aculeatus	74.26	4.00e-102	363.00
IUUC-Hsa-045965	Homo sapiens	97.88	5.00e-118	416.00
IUUC-Loc-052725	Lepisosteus oculatus	82.63	3.00e-102	363.00
IUUC-Mcc-055455	Macaca mulatta	96.94	3.00e-112	397.00
IUUC-Mtr-058089	Medicago truncatula	31.69	3.00e-34	138.00
IUUC-Mga-059312	Meleagris gallopavo	90.10	2.00e-98	350.00
IUUC-Mmr-061351	Microcebus murinus	96.92	5.00e-111	393.00
IUUC-Mdo-062282	Monodelphis domestica	95.76	4.00e-115	407.00
IUUC-Mmu-063201	Mus musculus	95.76	2.00e-121	427.00
IUUC-Mac-064625	Musa acuminata	33.07	4.00e-38	150.00
IUUC-Mpu-066302	Mustela putorius furo	97.88	5.00e-119	419.00
IUUC-Mlu-068192	Myotis lucifugus	97.46	9.00e-119	419.00
IUUC-Ont-072055	Oreochromis niloticus	76.79	6.00e-99	353.00
IUUC-Oan-073652	Ornithorhynchus anatinus	96.05	3.00e-114	404.00
IUUC-Ocu-073871	Oryctolagus cuniculus	95.78	5.00e-120	422.00
IUUC-Obr-076266	Oryza brachyantha	35.60	6.00e-37	147.00
IUUC-Ola-087103	Oryzias latipes	74.37	4.00e-93	333.00
IUUC-Oga-088066	Otolemur garnettii	87.14	7.00e-101	359.00
IUUC-Ptr-091665	Pan troglodytes	97.88	5.00e-118	416.00
IUUC-Pan-091875	Papio anubis	97.88	5.00e-118	416.00
IUUC-Psi-093904	Pelodiscus sinensis	92.96	3.00e-105	373.00
IUUC-Pfo-096981	Poecilia formosa	77.64	5.00e-99	353.00
IUUC-Pva-102282	Pteropus vampyrus	91.95	1.00e-123	435.00
IUUC-Rno-105646	Rattus norvegicus	95.34	8.00e-121	426.00
IUUC-Sha-107031	Sarcophilus harrisii	93.91	6.00e-109	386.00
IUUC-Smo-109441	Selaginella moellendorffii	36.93	6.00e-42	163.00
IUUC-Tgu-116837	Taeniopygia guttata	88.74	4.00e-112	397.00
IUUC-Tru-117974	Takifugu rubripes	76.05	8.00e-96	342.00
IUUC-Tni-120024	Tetraodon nigroviridis	75.53	2.00e-87	315.00
IUUC-Tca-121597	Theobroma cacao	33.61	6.00e-32	130.00
IUUC-Vvi-131487	Vitis vinifera	34.47	4.00e-34	137.00
IUUC-Xtr-132189	Xenopus tropicalis	82.98	2.00e-111	394.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence