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Tag Content
iUUCD ID IUUC-Fal-037113
Ensembl Protein ID ENSFALP00000010353.1
UniProt Accession U3K5P9; U3K5P9_FICAL
Genbank Protein ID ENSFALP00000010353
Protein Name Histone-lysine N-methyltransferase
Genbank Nucleotide ID AGTO01010340
Gene Name WHSC1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSFALG00000009928.1 ENSFALT00000010394.1 ENSFALP00000010353.1
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/PHD 1.50e-15 56.8 863 903
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/PHD
   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCr 52
           +C vC +gg+    l++Ce C  +fHp+Cl+++    +p+ + w+C++Cr
   Q: 863  WCFVCSKGGS----LLCCESCPAAFHPDCLNIE----MPDGS-WYCNDCR 903
           8*********....*******************....9***8.******8 PP
   
Organism Ficedula albicollis
Protein Sequence
(Fasta)
MDFSIKRSSQ LLTQKINYIK MKQVPEILGN TNGKPQNCEV NRECSVYLGK AQLSATLQEG 60
VMQKYNGHET LPFIPADKLK DLTSRVFNGE SGAQDAKLRF EPQEIKGVGT PPNTTPIKNG 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Fal-037113|E3,PHD|Ficedula albicollis
Please wait for a moment...
Nucleotide Sequence
(Fasta)
TCTGTCTTTT TGTCTTAATA TAGCAGTGTA AGACTGGAAA CATCTGGGCT GAATGGACTT 60
TAGCATCAAA AGAAGTTCTC AACTGTTAAC TCAAAAAATT AACTACATCA AAATGAAGCA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Fal-037113|E3,PHD|Ficedula albicollis
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0238--DNA-binding
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR006560--AWS_dom
IPR009071--HMG_box_dom
IPR003616--Post-SET_dom
IPR000313--PWWP_dom
IPR001214--SET_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS51215--AWS
PS50118--HMG_BOX_2
PS50868--POST_SET
PS50812--PWWP
PS50280--SET
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2
PS50089--ZF_RING_2
Pfam

PF00505--HMG_box
PF00855--PWWP
PF00856--SET
SMART

SM00570--AWS
SM00398--HMG
SM00249--PHD
SM00508--PostSET
SM00293--PWWP
SM00184--RING
SM00317--SET
Gene Ontology

GO:0005634--C:nucleus
GO:0003682--F:chromatin binding
GO:0018024--F:histone-lysine N-methyltransferase activity
GO:0043565--F:sequence-specific DNA binding
GO:0008270--F:zinc ion binding
GO:0003289--P:atrial septum primum morphogenesis
GO:0003290--P:atrial septum secundum morphogenesis
GO:0060348--P:bone development
GO:0010452--P:histone H3-K36 methylation
GO:0034770--P:histone H4-K20 methylation
GO:0003149--P:membranous septum morphogenesis
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0048298--P:positive regulation of isotype switching to IgA isotypes
GO:2001032--P:regulation of double-strand break repair via nonhomologous end joining
GO:0070201--P:regulation of establishment of protein localization
KEGG fab:101814945
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002181 Ailuropoda melanoleuca 79.87 0.00e+00 2108.00
IUUC-Apl-003677 Anas platyrhynchos 93.62 0.00e+00 2539.00
IUUC-Aca-004278 Anolis carolinensis 83.59 0.00e+00 1557.00
IUUC-Ame-011932 Astyanax mexicanus 71.01 0.00e+00 1073.00
IUUC-Bta-012522 Bos taurus 75.59 0.00e+00 1988.00
IUUC-Cja-018908 Callithrix jacchus 78.25 0.00e+00 2059.00
IUUC-Cfa-020894 Canis familiaris 79.05 0.00e+00 2130.00
IUUC-Cpo-021982 Cavia porcellus 77.36 0.00e+00 2077.00
IUUC-Csa-023807 Chlorocebus sabaeus 79.02 0.00e+00 2092.00
IUUC-Cho-024405 Choloepus hoffmanni 58.87 7.00e-177 613.00
IUUC-Csv-026298 Ciona savignyi 37.46 3.00e-56 212.00
IUUC-Dre-027492 Danio rerio 73.74 0.00e+00 1119.00
IUUC-Dno-030020 Dasypus novemcinctus 76.10 0.00e+00 1823.00
IUUC-Dor-031103 Dipodomys ordii 71.70 0.00e+00 1857.00
IUUC-Ete-032488 Echinops telfairi 73.52 0.00e+00 1904.00
IUUC-Eca-034066 Equus caballus 80.45 0.00e+00 2175.00
IUUC-Eeu-035199 Erinaceus europaeus 60.76 0.00e+00 646.00
IUUC-Fca-035434 Felis catus 75.13 0.00e+00 1738.00
IUUC-Gmo-039686 Gadus morhua 68.62 0.00e+00 1036.00
IUUC-Gga-040273 Gallus gallus 93.98 0.00e+00 2552.00
IUUC-Gac-042123 Gasterosteus aculeatus 50.29 0.00e+00 1252.00
IUUC-Ggo-044643 Gorilla gorilla 78.80 0.00e+00 2106.00
IUUC-Hsa-046380 Homo sapiens 78.97 0.00e+00 2082.00
IUUC-Itr-048658 Ictidomys tridecemlineatus 84.92 0.00e+00 1333.00
IUUC-Lch-050217 Latimeria chalumnae 66.59 0.00e+00 1779.00
IUUC-Lpe-051661 Leersia perrieri 29.90 3.00e-12 67.80
IUUC-Loc-052766 Lepisosteus oculatus 59.19 0.00e+00 1326.00
IUUC-Laf-053780 Loxodonta africana 79.88 0.00e+00 2162.00
IUUC-Mcc-054928 Macaca mulatta 79.17 0.00e+00 2122.00
IUUC-Meu-056184 Macropus eugenii 74.74 0.00e+00 801.00
IUUC-Mga-059576 Meleagris gallopavo 90.54 0.00e+00 2477.00
IUUC-Mmr-061045 Microcebus murinus 79.36 0.00e+00 2147.00
IUUC-Mdo-062576 Monodelphis domestica 86.58 0.00e+00 2303.00
IUUC-Mmu-063640 Mus musculus 77.11 0.00e+00 2065.00
IUUC-Mac-065303 Musa acuminata 29.41 6.00e-11 62.40
IUUC-Mpu-066512 Mustela putorius furo 79.87 0.00e+00 2110.00
IUUC-Mlu-067280 Myotis lucifugus 75.21 0.00e+00 1041.00
IUUC-Nle-069896 Nomascus leucogenys 79.39 0.00e+00 2019.00
IUUC-Ont-072197 Oreochromis niloticus 74.44 0.00e+00 1059.00
IUUC-Oan-072724 Ornithorhynchus anatinus 85.95 0.00e+00 1461.00
IUUC-Ocu-074758 Oryctolagus cuniculus 76.84 0.00e+00 2013.00
IUUC-Obr-076122 Oryza brachyantha 27.98 4.00e-11 61.20
IUUC-Ogu-078030 Oryza glumaepatula 30.15 3.00e-14 72.40
IUUC-Olo-080702 Oryza longistaminata 41.47 9.00e-45 175.00
IUUC-Opu-083371 Oryza punctata 44.72 7.00e-46 179.00
IUUC-Oga-088702 Otolemur garnettii 79.50 0.00e+00 1860.00
IUUC-Oar-089736 Ovis aries 70.66 0.00e+00 1761.00
IUUC-Ptr-091055 Pan troglodytes 78.90 0.00e+00 2083.00
IUUC-Pan-092752 Papio anubis 87.63 0.00e+00 1323.00
IUUC-Psi-093620 Pelodiscus sinensis 88.60 0.00e+00 2458.00
IUUC-Pfo-097464 Poecilia formosa 65.56 0.00e+00 1072.00
IUUC-Pab-098051 Pongo abelii 79.12 0.00e+00 2115.00
IUUC-Pop-099927 Populus trichocarpa 28.27 2.00e-11 63.90
IUUC-Pca-100273 Procavia capensis 78.81 0.00e+00 2109.00
IUUC-Ppe-101635 Prunus persica 27.47 6.00e-11 62.80
IUUC-Pva-102473 Pteropus vampyrus 69.35 0.00e+00 1749.00
IUUC-Rno-105056 Rattus norvegicus 77.44 0.00e+00 2080.00
IUUC-Sha-107494 Sarcophilus harrisii 87.04 0.00e+00 2275.00
IUUC-Sit-110333 Setaria italica 28.57 5.00e-10 59.30
IUUC-Sar-113310 Sorex araneus 78.25 0.00e+00 1638.00
IUUC-Sbi-114581 Sorghum bicolor 32.41 6.00e-09 54.70
IUUC-Ssc-116344 Sus scrofa 73.49 0.00e+00 1956.00
IUUC-Tgu-116786 Taeniopygia guttata 95.88 0.00e+00 2591.00
IUUC-Tru-117638 Takifugu rubripes 50.11 0.00e+00 1241.00
IUUC-Tsy-118937 Tarsius syrichta 85.77 0.00e+00 1412.00
IUUC-Tni-120452 Tetraodon nigroviridis 64.04 0.00e+00 1073.00
IUUC-Tae-125237 Triticum aestivum 30.87 4.00e-06 45.10
IUUC-Tbe-127291 Tupaia belangeri 76.31 0.00e+00 1350.00
IUUC-Ttr-129017 Tursiops truncatus 71.14 0.00e+00 1529.00
IUUC-Xtr-132673 Xenopus tropicalis 68.01 0.00e+00 1791.00
IUUC-Xma-133695 Xiphophorus maculatus 68.39 0.00e+00 1029.00
Created Date 25-Jun-2017

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