iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cfa-020355

Ensembl Protein ID

ENSCAFP00000026590.4

UniProt Accession

E2RAL2; E2RAL2_CANLF

Genbank Protein ID

ENSCAFP00000026590

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03005420

Gene Name

KLHL14

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000018002.4	ENSCAFT00000028589.4	ENSCAFP00000026590.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	7.20e-12	45.8	33	149

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmelees...................................................k 38
           +Dv+l  +g++f++hk+vLa++S++F++lf+++ + +                                                   +
   Q: 33   CDVTLTAQGQQFHCHKAVLASCSQYFRSLFSSHPPLGggvggqdglgapkdqqqqppqqqppqqqqpppqeepgtpssspddklltspR 121
           9*********************************9777************************************************997 PP
   S: 39   sklmveikdvqpevfrallkFlYtgkld 66
             +  ++++ +   +r +l++lYt  ++
   Q: 122  AINNLVLQGCSSIGLRLVLEYLYTANVT 149
           79999999****************9876 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MSRSGDRTST FDPSHSDNLL HGLNLLWRKQ LFCDVTLTAQ GQQFHCHKAV LASCSQYFRS 60
LFSSHPPLGG GVGGQDGLGA PKDQQQQPPQ QQPPQQQQPP PQEEPGTPSS SPDDKLLTSP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTTGGAGGAG GGTTTAAAGC CAGGTGCGCC GAGTCAGCTC GCCATGTCCA GATCCGGGGA 60
CAGGACCTCC ACCTTCGACC CCAGCCACAG CGACAACCTG CTGCACGGCC TCAACCTGCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030584--KLHL14
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0016235--C:aggresome
GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005829--C:cytosol
GO:0005783--C:endoplasmic reticulum
GO:0043005--C:neuron projection
GO:0043025--C:neuronal cell body
GO:0016567--P:protein ubiquitination

KEGG

cfa:490494

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001196	Ailuropoda melanoleuca	97.48	1.00e-177	615.00
IUUC-Bta-012869	Bos taurus	97.62	0.00e+00	1186.00
IUUC-Cja-018731	Callithrix jacchus	96.82	0.00e+00	1189.00
IUUC-Cpo-021612	Cavia porcellus	98.41	0.00e+00	1174.00
IUUC-Csa-023993	Chlorocebus sabaeus	99.05	0.00e+00	1172.00
IUUC-Dre-027629	Danio rerio	86.49	0.00e+00	1077.00
IUUC-Dno-029185	Dasypus novemcinctus	98.25	0.00e+00	1192.00
IUUC-Fca-036303	Felis catus	99.21	0.00e+00	1192.00
IUUC-Fal-037175	Ficedula albicollis	93.32	0.00e+00	1147.00
IUUC-Gmo-038807	Gadus morhua	86.03	0.00e+00	1061.00
IUUC-Gga-040750	Gallus gallus	92.88	0.00e+00	1138.00
IUUC-Gac-041372	Gasterosteus aculeatus	85.06	0.00e+00	1065.00
IUUC-Ggo-044702	Gorilla gorilla	94.61	0.00e+00	1157.00
IUUC-Hsa-046282	Homo sapiens	97.93	0.00e+00	1168.00
IUUC-Lch-049564	Latimeria chalumnae	90.95	0.00e+00	1144.00
IUUC-Loc-051831	Lepisosteus oculatus	89.83	0.00e+00	1129.00
IUUC-Laf-054353	Loxodonta africana	97.30	0.00e+00	1192.00
IUUC-Mcc-055080	Macaca mulatta	99.16	4.00e-173	600.00
IUUC-Meu-056733	Macropus eugenii	85.93	0.00e+00	819.00
IUUC-Mmr-061263	Microcebus murinus	99.36	0.00e+00	1173.00
IUUC-Mdo-061930	Monodelphis domestica	88.89	0.00e+00	1058.00
IUUC-Mmu-064251	Mus musculus	98.41	0.00e+00	1194.00
IUUC-Mpu-066871	Mustela putorius furo	99.52	0.00e+00	1200.00
IUUC-Mlu-067725	Myotis lucifugus	83.54	0.00e+00	913.00
IUUC-Nle-069427	Nomascus leucogenys	98.57	0.00e+00	1167.00
IUUC-Ont-072429	Oreochromis niloticus	86.96	0.00e+00	1088.00
IUUC-Ocu-074635	Oryctolagus cuniculus	98.10	0.00e+00	1195.00
IUUC-Ola-086870	Oryzias latipes	88.25	0.00e+00	1090.00
IUUC-Oga-088397	Otolemur garnettii	98.89	0.00e+00	1193.00
IUUC-Oar-089280	Ovis aries	99.41	0.00e+00	1021.00
IUUC-Ptr-091356	Pan troglodytes	92.05	0.00e+00	1083.00
IUUC-Pan-092718	Papio anubis	99.05	0.00e+00	1172.00
IUUC-Psi-093970	Pelodiscus sinensis	91.95	0.00e+00	1084.00
IUUC-Pfo-096550	Poecilia formosa	86.98	0.00e+00	1085.00
IUUC-Pab-097802	Pongo abelii	98.41	0.00e+00	1162.00
IUUC-Pca-101125	Procavia capensis	94.28	0.00e+00	1116.00
IUUC-Pva-102888	Pteropus vampyrus	98.63	0.00e+00	1098.00
IUUC-Rno-105007	Rattus norvegicus	98.25	0.00e+00	1194.00
IUUC-Sar-113671	Sorex araneus	96.19	0.00e+00	1154.00
IUUC-Ssc-116060	Sus scrofa	98.25	0.00e+00	1195.00
IUUC-Tgu-116795	Taeniopygia guttata	85.87	0.00e+00	1016.00
IUUC-Tru-118216	Takifugu rubripes	88.10	0.00e+00	1111.00
IUUC-Tsy-118816	Tarsius syrichta	96.33	0.00e+00	634.00
IUUC-Tni-120281	Tetraodon nigroviridis	80.23	0.00e+00	957.00
IUUC-Tbe-128057	Tupaia belangeri	94.92	0.00e+00	1121.00
IUUC-Ttr-128618	Tursiops truncatus	84.90	0.00e+00	1023.00
IUUC-Vpa-130468	Vicugna pacos	99.52	0.00e+00	736.00
IUUC-Xtr-132753	Xenopus tropicalis	89.07	0.00e+00	1102.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence