iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Laf-054353

Ensembl Protein ID

ENSLAFP00000013950.4

UniProt Accession

G3THC5; G3THC5_LOXAF

Protein Name

Uncharacterized protein

Gene Name

KLHL14

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000016617.4	ENSLAFT00000016617.4	ENSLAFP00000013950.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	7.30e-12	45.8	33	146

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmelees................................................kskl 41
           +Dv+l  +g++f++hk+vLa++S++F++lf+++ + +                                                +  +
   Q: 33   CDVTLTAQGQQFHCHKAVLASCSQYFRSLFSSHPPLGggvggqdglgapkdqqqpqqqppqqqpppqedpgtpssspddklltspRAIN 121
           9*********************************9777*********************************************997799 PP
   S: 42   mveikdvqpevfrallkFlYtgkld 66
             ++++ +   +r +l++lYt  ++
   Q: 122  NLVLQGCSSIGLRLVLEYLYTANVT 146
           99999****************9876 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MSRSGDRTST FDPSHSDNLL HGLNLLWRKQ LFCDVTLTAQ GQQFHCHKAV LASCSQYFRS 60
LFSSHPPLGG GVGGQDGLGA PKDQQQPQQQ PPQQQPPPQE DPGTPSSSPD DKLLTSPRAI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCCAGAT CCGGGGACAG GACCTCCACC TTCGACCCCA GCCACAGCGA CAACCTGCTG 60
CACGGCCTCA ACCTGCTGTG GAGGAAGCAG CTGTTTTGCG ACGTGACCCT GACGGCCCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030584--KLHL14
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0016235--C:aggresome
GO:0005829--C:cytosol
GO:0005783--C:endoplasmic reticulum
GO:0043005--C:neuron projection
GO:0043025--C:neuronal cell body

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001196	Ailuropoda melanoleuca	97.46	2.00e-178	617.00
IUUC-Bta-012869	Bos taurus	97.28	0.00e+00	1189.00
IUUC-Cja-018731	Callithrix jacchus	97.12	0.00e+00	1189.00
IUUC-Cfa-020355	Canis familiaris	97.30	0.00e+00	1192.00
IUUC-Cpo-021612	Cavia porcellus	96.66	0.00e+00	1169.00
IUUC-Csa-023993	Chlorocebus sabaeus	96.18	0.00e+00	1167.00
IUUC-Dre-027629	Danio rerio	86.58	0.00e+00	1078.00
IUUC-Dno-029185	Dasypus novemcinctus	96.98	0.00e+00	1191.00
IUUC-Fca-036303	Felis catus	97.14	0.00e+00	1186.00
IUUC-Fal-037175	Ficedula albicollis	93.29	0.00e+00	1149.00
IUUC-Gmo-038807	Gadus morhua	86.28	0.00e+00	1062.00
IUUC-Gga-040750	Gallus gallus	94.12	0.00e+00	1143.00
IUUC-Gac-041372	Gasterosteus aculeatus	85.46	0.00e+00	1067.00
IUUC-Ggo-044702	Gorilla gorilla	94.90	0.00e+00	1157.00
IUUC-Hsa-046282	Homo sapiens	96.82	0.00e+00	1167.00
IUUC-Lch-049564	Latimeria chalumnae	91.55	0.00e+00	1147.00
IUUC-Loc-051831	Lepisosteus oculatus	90.26	0.00e+00	1129.00
IUUC-Mcc-055080	Macaca mulatta	93.85	3.00e-171	594.00
IUUC-Meu-056733	Macropus eugenii	85.18	0.00e+00	816.00
IUUC-Mmr-061263	Microcebus murinus	96.18	0.00e+00	1169.00
IUUC-Mdo-061930	Monodelphis domestica	88.42	0.00e+00	1057.00
IUUC-Mmu-064251	Mus musculus	97.46	0.00e+00	1192.00
IUUC-Mpu-066871	Mustela putorius furo	97.77	0.00e+00	1194.00
IUUC-Mlu-067725	Myotis lucifugus	83.52	0.00e+00	809.00
IUUC-Nle-069427	Nomascus leucogenys	96.35	0.00e+00	1167.00
IUUC-Ont-072429	Oreochromis niloticus	87.38	0.00e+00	1089.00
IUUC-Ocu-074635	Oryctolagus cuniculus	96.67	0.00e+00	1190.00
IUUC-Ola-086870	Oryzias latipes	88.68	0.00e+00	1091.00
IUUC-Oga-088397	Otolemur garnettii	97.46	0.00e+00	1192.00
IUUC-Oar-089280	Ovis aries	99.41	0.00e+00	1021.00
IUUC-Ptr-091356	Pan troglodytes	91.72	0.00e+00	1082.00
IUUC-Pan-092718	Papio anubis	96.18	0.00e+00	1167.00
IUUC-Psi-093970	Pelodiscus sinensis	92.23	0.00e+00	1085.00
IUUC-Pfo-096550	Poecilia formosa	87.40	0.00e+00	1087.00
IUUC-Pab-097802	Pongo abelii	95.55	0.00e+00	1157.00
IUUC-Pca-101125	Procavia capensis	92.53	0.00e+00	1110.00
IUUC-Pva-102888	Pteropus vampyrus	97.94	0.00e+00	1097.00
IUUC-Rno-105007	Rattus norvegicus	97.46	0.00e+00	1192.00
IUUC-Sar-113671	Sorex araneus	95.07	0.00e+00	1153.00
IUUC-Ssc-116060	Sus scrofa	97.62	0.00e+00	1194.00
IUUC-Tgu-116795	Taeniopygia guttata	84.69	0.00e+00	1016.00
IUUC-Tru-118216	Takifugu rubripes	88.52	0.00e+00	1111.00
IUUC-Tsy-118816	Tarsius syrichta	96.33	0.00e+00	633.00
IUUC-Tni-120281	Tetraodon nigroviridis	84.69	0.00e+00	1026.00
IUUC-Tbe-128057	Tupaia belangeri	93.17	0.00e+00	1115.00
IUUC-Ttr-128618	Tursiops truncatus	84.98	0.00e+00	1025.00
IUUC-Vpa-130468	Vicugna pacos	96.61	0.00e+00	732.00
IUUC-Xtr-132753	Xenopus tropicalis	89.50	0.00e+00	1103.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence