iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cpo-021592

Ensembl Protein ID

ENSCPOP00000006201.2

UniProt Accession

H0V8T5; H0V8T5_CAVPO

Genbank Protein ID

ENSCPOP00000006201

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02033272

Gene Name

CRK

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000006877.3	ENSCPOT00000006946.2	ENSCPOP00000006201.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.40e-18	66.5	133	188

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 3    kekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
            e+v++l+d++++++++L +kkGd++++   ++ +e W+++ ++ egkrG++P  +vek
   Q: 133  AEYVRALFDFNGNDEEDLPFKKGDILRI--RDKPEEQWWNA-EDSEGKRGMIPVPYVEK 188
           689*************************..6999******9.5**************98 PP

Organism

Cavia porcellus

Protein Sequence
(Fasta)

LAKNTGPETT SSSWYWGRSR QEAVALLQGQ PHRAGLEHPA PGDYVLSVLR ELSRLSLHHQ 60
QASGPAPPRC HRRPLKPPPG MNPSRLRIGD QEFDSLPALL EFYKIHYLDT TTLIEPVSRS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTTGCTAAGA ACACAGGCCC TGAGACCACA TCTTTCCTAA CCCAATTCTT TTTCCTTTTT 60
TTGCCTCCTG AGTGTTGAGA TTACAGGTGT GCACCACTAC GACTAGCATT TTTTTTCAGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR000980--SH2
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS50002--SH3

Pfam

PF00018--SH3_1
PF07653--SH3_2

PRINTS

PR00452--SH3DOMAIN

SMART

SM00252--SH2
SM00326--SH3

Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0070062--C:extracellular exosome
GO:0048013--P:ephrin receptor signaling pathway
GO:0009967--P:positive regulation of signal transduction
GO:1900026--P:positive regulation of substrate adhesion-dependent cell spreading
GO:0032956--P:regulation of actin cytoskeleton organization
GO:0043087--P:regulation of GTPase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001192	Ailuropoda melanoleuca	88.18	2.00e-138	484.00
IUUC-Apl-003225	Anas platyrhynchos	92.11	5.00e-123	433.00
IUUC-Aca-004818	Anolis carolinensis	77.92	4.00e-92	330.00
IUUC-Bta-012320	Bos taurus	88.18	1.00e-138	485.00
IUUC-Cja-019935	Callithrix jacchus	87.16	6.00e-145	506.00
IUUC-Cfa-021221	Canis familiaris	88.18	7.00e-138	483.00
IUUC-Csa-024128	Chlorocebus sabaeus	82.05	1.00e-76	278.00
IUUC-Cho-024775	Choloepus hoffmanni	86.15	8.00e-138	482.00
IUUC-Dre-027390	Danio rerio	62.30	2.00e-97	348.00
IUUC-Dno-029847	Dasypus novemcinctus	88.18	1.00e-138	485.00
IUUC-Dor-030360	Dipodomys ordii	83.11	5.00e-135	473.00
IUUC-Ete-032604	Echinops telfairi	95.52	2.00e-124	437.00
IUUC-Eca-033233	Equus caballus	86.33	4.00e-140	490.00
IUUC-Eeu-034642	Erinaceus europaeus	96.86	1.00e-126	445.00
IUUC-Fca-035955	Felis catus	98.22	2.00e-130	457.00
IUUC-Fal-037152	Ficedula albicollis	82.62	1.00e-131	461.00
IUUC-Gmo-038849	Gadus morhua	62.21	6.00e-97	347.00
IUUC-Gga-040861	Gallus gallus	81.02	6.00e-132	463.00
IUUC-Gac-041627	Gasterosteus aculeatus	58.93	2.00e-97	348.00
IUUC-Ggo-045475	Gorilla gorilla	88.18	1.00e-138	485.00
IUUC-Hsa-046008	Homo sapiens	88.18	1.00e-138	485.00
IUUC-Itr-048906	Ictidomys tridecemlineatus	85.77	7.00e-109	386.00
IUUC-Lch-050509	Latimeria chalumnae	76.49	3.00e-128	451.00
IUUC-Loc-052229	Lepisosteus oculatus	66.03	1.00e-85	309.00
IUUC-Laf-053896	Loxodonta africana	86.58	2.00e-144	504.00
IUUC-Mcc-055280	Macaca mulatta	88.18	1.00e-138	485.00
IUUC-Meu-056783	Macropus eugenii	96.86	1.00e-126	444.00
IUUC-Mga-059345	Meleagris gallopavo	93.27	3.00e-124	437.00
IUUC-Mdo-062691	Monodelphis domestica	82.35	2.00e-136	478.00
IUUC-Mmu-063691	Mus musculus	87.84	3.00e-138	484.00
IUUC-Mpu-065737	Mustela putorius furo	88.18	1.00e-138	485.00
IUUC-Mlu-067005	Myotis lucifugus	85.14	9.00e-134	469.00
IUUC-Nle-070154	Nomascus leucogenys	98.22	4.00e-130	456.00
IUUC-Opr-071114	Ochotona princeps	87.84	3.00e-145	507.00
IUUC-Oan-072967	Ornithorhynchus anatinus	82.14	5.00e-107	380.00
IUUC-Ocu-074025	Oryctolagus cuniculus	81.03	4.00e-75	273.00
IUUC-Oga-088266	Otolemur garnettii	86.82	2.00e-137	481.00
IUUC-Oar-089221	Ovis aries	86.49	1.00e-135	475.00
IUUC-Ptr-091463	Pan troglodytes	87.03	1.00e-135	475.00
IUUC-Pan-092242	Papio anubis	87.84	1.00e-138	485.00
IUUC-Psi-093287	Pelodiscus sinensis	95.54	2.00e-127	447.00
IUUC-Pab-097823	Pongo abelii	82.05	1.00e-76	278.00
IUUC-Pca-101068	Procavia capensis	88.18	1.00e-138	485.00
IUUC-Pgr-103636	Puccinia graminis	36.84	3.00e-09	55.50
IUUC-Ptt-103815	Puccinia triticina	37.93	1.00e-09	56.60
IUUC-Rno-105288	Rattus norvegicus	87.84	4.00e-138	483.00
IUUC-Sar-113453	Sorex araneus	79.59	4.00e-129	453.00
IUUC-Tgu-116926	Taeniopygia guttata	81.42	9.00e-131	459.00
IUUC-Tru-118656	Takifugu rubripes	60.12	3.00e-99	354.00
IUUC-Tni-120497	Tetraodon nigroviridis	62.34	6.00e-95	340.00
IUUC-Tbe-127436	Tupaia belangeri	83.11	3.00e-120	424.00
IUUC-Ttr-129109	Tursiops truncatus	98.65	1.00e-129	454.00
IUUC-Vpa-130527	Vicugna pacos	87.84	1.00e-136	478.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence