iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mga-059884

UUCD1 version

UUC-MeG-00395

Ensembl Protein ID

ENSMGAP00000008768.2

UniProt Accession

G1N8U0; G1N8U0_MELGA

Protein Name

Uncharacterized protein

Gene Name

HECTD2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000008530.2	ENSMGAT00000009572.2	ENSMGAP00000008768.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	2.00e-102	342.7	393	731

Active Site

Position(s)	Description	Evidence
699	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldl 90
           ++dlkk+l+v+fvgE+gld+gG+t+e++ ll++++++pd+g+f+y+++++++++ + +      ++ + F+++G l+g+a++++  ld+
   Q: 393  RADLKKKLKVTFVGEAGLDMGGLTKEWFLLLIRQIFHPDYGMFTYHKDSHCHWFSSFKC-----DNYSEFRLVGALMGLAVYNSITLDI 476
           589***************************************************87766.....789********************** PP
   S: 91   plsksfyklllgk..............klsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipV 165
           ++++++yk+ll+               +++l+dl +++pel++ l e++++ e ++ee  +  tf+v +e++g +k+++Lkp+G++ipV
   Q: 477  RFPPCCYKKLLSPpivpcdhntlvgicDVTLDDLFQIMPELAHGLSELLSY-EGNVEED-FYSTFQVFQEEFGVIKSYNLKPNGDKIPV 563
           ***********99666666666666666**********************9.6788885.***************************** PP
   S: 166  tneNkeeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevle 254
           tn+N++eYv+l+v++ l+++i +q++af+ Gf++v+    l l+++ee+e+l+cG++e+d+++l++ t+y+ gy++++ +i++Fw+v+ 
   Q: 564  TNQNRKEYVQLYVDFLLNKSIYKQFAAFYYGFHSVCASYALLLLRPEEVEILVCGSPELDMSALQRSTQYE-GYQKTDVTIRYFWDVVL 651
           **********************************************************************5.5**************** PP
   S: 255  efsseerkafLqFvTgssrlPlgGfaelkprlfvirk.dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFels 336
           +fs + +k++L+F+Tgs+r+P+gG+a+l+   f i+k ++s+++lP ++TCfn+L+LP+Y++k++lk+kL++ i++++gF+l+
   Q: 652  GFSLDLQKKLLHFATGSDRVPVGGMADLN---FKISKsETSTNWLPVAHTCFNQLCLPPYKNKKELKQKLIIGISNAEGFGLE 731
           *****************************...9999967777**************************************985 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

GLERGAKNQF STFSNFITTI NQKKEGTGNR SSPTQLVIPS IKNVRDLPPI CLDVRQKQRI 60
SIDTLPQELK APVPHQPSLP IRTKTVKDFQ DDMEKAKSSG DWKAVHEFYS TTFDSFLEIN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGATTGGAAA GAGGAGCAAA AAATCAGTTT TCTACTTTCA GCAATTTCAT CACAACTATC 60
AACCAAAAGA AAGAAGGCAC CGGAAACAGA AGTTCGCCCA CACAGCTTGT TATACCAAGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001266	Ailuropoda melanoleuca	79.62	0.00e+00	1192.00
IUUC-Apl-003589	Anas platyrhynchos	87.89	0.00e+00	1273.00
IUUC-Aca-004350	Anolis carolinensis	76.70	0.00e+00	1113.00
IUUC-Ago-007908	Ashbya gossypii	36.34	1.00e-78	287.00
IUUC-Acl-008288	Aspergillus clavatus	39.81	9.00e-86	311.00
IUUC-Afl-008402	Aspergillus flavus	38.39	2.00e-79	290.00
IUUC-Afu-008762	Aspergillus fumigatus	39.01	2.00e-83	303.00
IUUC-Ani-009176	Aspergillus nidulans	39.30	5.00e-83	302.00
IUUC-Ang-009791	Aspergillus niger	39.50	3.00e-81	296.00
IUUC-Aor-009921	Aspergillus oryzae	38.15	1.00e-78	287.00
IUUC-Ate-010295	Aspergillus terreus	40.71	3.00e-90	326.00
IUUC-Ame-010660	Astyanax mexicanus	82.94	1.00e-153	535.00
IUUC-Bgr-011981	Blumeria graminis	40.14	8.00e-86	311.00
IUUC-Bta-012945	Bos taurus	79.64	0.00e+00	1163.00
IUUC-Bci-013697	Botrytis cinerea	39.86	1.00e-75	278.00
IUUC-Cja-019263	Callithrix jacchus	77.72	0.00e+00	1147.00
IUUC-Cfa-020486	Canis familiaris	81.76	0.00e+00	1070.00
IUUC-Cpo-021755	Cavia porcellus	78.83	0.00e+00	1155.00
IUUC-Csa-023814	Chlorocebus sabaeus	78.35	0.00e+00	1086.00
IUUC-Cho-024980	Choloepus hoffmanni	66.53	0.00e+00	939.00
IUUC-Cgl-026526	Colletotrichum gloeosporioides	41.04	2.00e-87	317.00
IUUC-Dre-028551	Danio rerio	71.04	0.00e+00	1040.00
IUUC-Dno-029497	Dasypus novemcinctus	78.61	0.00e+00	1060.00
IUUC-Dor-030867	Dipodomys ordii	87.07	0.00e+00	689.00
IUUC-Dse-031239	Dothistroma septosporum	37.22	1.00e-82	301.00
IUUC-Ete-032902	Echinops telfairi	66.12	0.00e+00	931.00
IUUC-Eca-033678	Equus caballus	79.37	0.00e+00	1164.00
IUUC-Eeu-035262	Erinaceus europaeus	68.60	0.00e+00	912.00
IUUC-Fca-035590	Felis catus	80.46	0.00e+00	1192.00
IUUC-Fal-037123	Ficedula albicollis	83.90	0.00e+00	1201.00
IUUC-Fso-038388	Fusarium solani	42.73	2.00e-93	337.00
IUUC-Gmo-039553	Gadus morhua	62.05	0.00e+00	782.00
IUUC-Ggr-040110	Gaeumannomyces graminis	42.32	5.00e-93	335.00
IUUC-Gga-040406	Gallus gallus	89.65	0.00e+00	1328.00
IUUC-Gac-042141	Gasterosteus aculeatus	70.66	0.00e+00	997.00
IUUC-Ggo-045504	Gorilla gorilla	77.72	0.00e+00	1152.00
IUUC-Hsa-045786	Homo sapiens	78.83	0.00e+00	1156.00
IUUC-Itr-048050	Ictidomys tridecemlineatus	75.04	0.00e+00	1013.00
IUUC-Kpa-049152	Komagataella pastoris	36.79	1.00e-71	264.00
IUUC-Lch-049824	Latimeria chalumnae	75.32	0.00e+00	998.00
IUUC-Loc-052173	Lepisosteus oculatus	73.81	0.00e+00	1055.00
IUUC-Laf-054017	Loxodonta africana	80.70	0.00e+00	1122.00
IUUC-Mcc-055713	Macaca mulatta	78.40	0.00e+00	1144.00
IUUC-Meu-056212	Macropus eugenii	68.21	2.00e-111	395.00
IUUC-Mor-057045	Magnaporthe oryzae	38.94	3.00e-84	306.00
IUUC-Mla-059187	Melampsora laricipopulina	44.09	4.00e-85	308.00
IUUC-Mmr-061344	Microcebus murinus	78.80	0.00e+00	1148.00
IUUC-Mdo-062653	Monodelphis domestica	78.46	0.00e+00	1145.00
IUUC-Mmu-063775	Mus musculus	77.87	0.00e+00	1112.00
IUUC-Mpu-066069	Mustela putorius furo	80.72	0.00e+00	1080.00
IUUC-Mlu-067925	Myotis lucifugus	79.64	0.00e+00	1157.00
IUUC-Nfi-068439	Neosartorya fischeri	39.01	2.00e-83	303.00
IUUC-Ncr-068903	Neurospora crassa	39.90	2.00e-86	314.00
IUUC-Nle-070046	Nomascus leucogenys	78.12	0.00e+00	1150.00
IUUC-Opr-071085	Ochotona princeps	75.50	1.00e-131	463.00
IUUC-Ont-072126	Oreochromis niloticus	69.43	0.00e+00	1048.00
IUUC-Oan-072933	Ornithorhynchus anatinus	80.00	0.00e+00	1048.00
IUUC-Ocu-073800	Oryctolagus cuniculus	80.87	0.00e+00	1080.00
IUUC-Ola-086988	Oryzias latipes	71.41	0.00e+00	1008.00
IUUC-Oga-088117	Otolemur garnettii	79.73	0.00e+00	928.00
IUUC-Oar-089371	Ovis aries	79.78	0.00e+00	1146.00
IUUC-Ptr-090551	Pan troglodytes	77.47	0.00e+00	1122.00
IUUC-Pan-092067	Papio anubis	79.23	0.00e+00	1145.00
IUUC-Psi-092963	Pelodiscus sinensis	81.47	0.00e+00	1156.00
IUUC-Pfo-096562	Poecilia formosa	66.71	0.00e+00	1001.00
IUUC-Pab-098680	Pongo abelii	78.83	0.00e+00	1155.00
IUUC-Pca-100986	Procavia capensis	62.96	0.00e+00	704.00
IUUC-Pva-102219	Pteropus vampyrus	83.84	0.00e+00	679.00
IUUC-Pgr-103315	Puccinia graminis	41.00	2.00e-89	323.00
IUUC-Ptt-103736	Puccinia triticina	41.74	3.00e-91	329.00
IUUC-Rno-105270	Rattus norvegicus	78.01	0.00e+00	1115.00
IUUC-Sce-106306	Saccharomyces cerevisiae	35.78	1.00e-65	244.00
IUUC-Sha-106819	Sarcophilus harrisii	80.03	0.00e+00	1192.00
IUUC-Spo-108271	Schizosaccharomyces pombe	34.55	5.00e-76	278.00
IUUC-Ssl-108657	Sclerotinia sclerotiorum	39.39	3.00e-77	283.00
IUUC-Sar-113134	Sorex araneus	70.90	0.00e+00	1001.00
IUUC-Ssc-115441	Sus scrofa	80.16	0.00e+00	1170.00
IUUC-Tgu-117166	Taeniopygia guttata	86.10	0.00e+00	1216.00
IUUC-Tsy-118898	Tarsius syrichta	67.03	0.00e+00	915.00
IUUC-Tre-122108	Trichoderma reesei	39.29	4.00e-84	306.00
IUUC-Tvi-122644	Trichoderma virens	40.00	2.00e-86	313.00
IUUC-Tme-127004	Tuber melanosporum	41.86	2.00e-91	330.00
IUUC-Tbe-127292	Tupaia belangeri	60.79	0.00e+00	809.00
IUUC-Ttr-128352	Tursiops truncatus	75.96	0.00e+00	1098.00
IUUC-Vda-129969	Verticillium dahliae	39.62	2.00e-84	307.00
IUUC-Vpa-130218	Vicugna pacos	74.31	0.00e+00	776.00
IUUC-Xtr-132594	Xenopus tropicalis	72.40	0.00e+00	1038.00
IUUC-Xma-134157	Xiphophorus maculatus	69.38	0.00e+00	924.00
IUUC-Yli-134470	Yarrowia lipolytica	37.68	2.00e-73	270.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence