iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oan-072893

UUCD1 version

UUC-OrA-00012

Ensembl Protein ID

ENSOANP00000013459.1

UniProt Accession

F6PJ35; F6PJ35_ORNAN

Protein Name

Uncharacterized protein

Gene Name

UBR2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000008465.3	ENSOANT00000013462.2	ENSOANP00000013459.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.80e-09	38.2	1108	1213
E3 activity/N-recognin/N-domain	4.60e-39	132.6	227	302
E3 activity/N-recognin/UBR-box	1.10e-30	106.1	97	167

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiC......................................ledf........kdgplvlpCgHvfhadClqkw............ 29
           C++C                                      +           ++g+++++CgH++ha+C+q++            
   Q: 1108 CILCqeeqevkvdnramvlaafvqrstvlsknrnkviqdpekY--DplfmhpdlSCGTHTGSCGHIMHAHCWQRYfdavqakeqrrq 1192
           8888333333333333333333333333333333333333321..02244444455899**************************** PP
   S: 30   .....pglknssskefrCPlC 45
                + +++++++ef+CPlC
   Q: 1193 qrlrvHTSYDVENGEFLCPLC 1213
           ********************* PP

E3 activity/N-recognin/N-domain

   S: 1    YylvLfNDEkHsyeqviyslqkAleleqkeakkfatiidkeGRravkaGdyavceeakkeilknseklaqipLkVev 77
           Yy++LfNDE+H+y+qviy+lqkA+ ++qkea++fat++d++GRr+v++Gd+++ce+ak++i++n++++++ pLkV+v
   Q: 227  YYCMLFNDEVHTYDQVIYTLQKAVSCTQKEAIGFATTVDRDGRRSVRYGDFQYCEQAKSVIVRNTSRQTK-PLKVQV 302
           9*********************************************************************.****98 PP

E3 activity/N-recognin/UBR-box

   S: 1    slCgrvfkvgetiyeCrtCsvdetlvlCteCfakvvHkdHeyklkksggggfCdCGdteAwedgskCkkll 71
           +lCgrvfkvge +y+Cr+C+vd+t+vlC+eCf  ++H++H+y++++sggggfCdCGdteAw++g++C+k+ 
   Q: 97   HLCGRVFKVGEPTYSCRDCAVDPTCVLCMECFLGSIHREHRYRMTTSGGGGFCDCGDTEAWKEGPYCQKHD 167
           68******************************************************************996 PP

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

MASDLEPEVQ AIDRSLLECS AEETAGKWLQ ATDLPREVFR HLAHYVPKIY CCGPNPTPQR 60
EDMLAQHVLL GPMEWYICGE DPAVGFPKLE QANKPSHLCG RVFKVGEPTY SCRDCAVDPT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCCTGCTTA GGCTGCTAAG GAATGGGATC ATCCGAGCAA GCTACTTAAA CTTCCCTGAG 60
CCTGTCTCCT TCTCTGGTCA GGGAGGGTGA CCGAGGCCTT CAGGTTCCTG GGGGCAACTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR003769--ClpS_core
IPR014719--Ribosomal_L7/12_C/ClpS-like
IPR011991--WHTH_DNA-bd_dom
IPR013083--Znf_RING/FYVE/PHD
IPR003126--Znf_UBR

PROSITE

PS51157--ZF_UBR

Pfam

PF02617--ClpS
PF02207--zf-UBR

SMART

SM00396--ZnF_UBR1

Gene Ontology

GO:0000785--C:chromatin
GO:0005737--C:cytoplasm
GO:0000151--C:ubiquitin ligase complex
GO:0070728--F:leucine binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0071233--P:cellular response to leucine
GO:0006342--P:chromatin silencing
GO:0033522--P:histone H2A ubiquitination
GO:0007141--P:male meiosis I
GO:0032007--P:negative regulation of TOR signaling
GO:0007283--P:spermatogenesis
GO:0071596--P:ubiquitin-dependent protein catabolic process via the N-end rule pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000949	Aegilops tauschii	26.39	2.00e-21	98.20
IUUC-Aml-001876	Ailuropoda melanoleuca	79.98	0.00e+00	2582.00
IUUC-Atr-002501	Amborella trichopoda	29.68	4.00e-28	120.00
IUUC-Apl-003828	Anas platyrhynchos	88.41	0.00e+00	3089.00
IUUC-Aca-005189	Anolis carolinensis	86.67	0.00e+00	3061.00
IUUC-Aly-005901	Arabidopsis lyrata	31.46	4.00e-25	110.00
IUUC-Ath-007148	Arabidopsis thaliana	30.05	8.00e-24	106.00
IUUC-Ago-007946	Ashbya gossypii	22.12	4.00e-24	107.00
IUUC-Acl-008055	Aspergillus clavatus	25.04	1.00e-35	145.00
IUUC-Afl-008479	Aspergillus flavus	23.30	5.00e-47	183.00
IUUC-Afu-008929	Aspergillus fumigatus	24.22	3.00e-54	207.00
IUUC-Ani-009334	Aspergillus nidulans	24.46	5.00e-51	197.00
IUUC-Ang-009550	Aspergillus niger	24.39	6.00e-48	186.00
IUUC-Aor-010124	Aspergillus oryzae	23.45	4.00e-47	183.00
IUUC-Ate-010550	Aspergillus terreus	24.06	2.00e-32	135.00
IUUC-Ame-011917	Astyanax mexicanus	74.43	0.00e+00	2524.00
IUUC-Bgr-011999	Blumeria graminis	21.16	1.00e-43	172.00
IUUC-Bta-012768	Bos taurus	87.81	0.00e+00	3093.00
IUUC-Bci-013834	Botrytis cinerea	24.47	8.00e-35	143.00
IUUC-Bdi-014635	Brachypodium distachyon	24.05	6.00e-29	123.00
IUUC-Bol-015669	Brassica oleracea	30.39	2.00e-29	124.00
IUUC-Bra-017776	Brassica rapa	30.39	7.00e-30	126.00
IUUC-Cel-018476	Caenorhabditis elegans	32.10	1.00e-84	308.00
IUUC-Cja-019797	Callithrix jacchus	87.77	0.00e+00	2417.00
IUUC-Cfa-020950	Canis familiaris	89.29	0.00e+00	3130.00
IUUC-Cpo-022385	Cavia porcellus	87.69	0.00e+00	3112.00
IUUC-Csa-024082	Chlorocebus sabaeus	89.06	0.00e+00	3128.00
IUUC-Cho-025029	Choloepus hoffmanni	81.52	0.00e+00	2060.00
IUUC-Cin-025148	Ciona intestinalis	35.19	3.00e-136	478.00
IUUC-Csv-026296	Ciona savignyi	31.84	4.00e-23	101.00
IUUC-Cgl-026605	Colletotrichum gloeosporioides	23.31	1.00e-54	209.00
IUUC-Cne-026823	Cryptococcus neoformans	22.66	7.00e-39	156.00
IUUC-Dre-028343	Danio rerio	74.41	0.00e+00	2554.00
IUUC-Dno-030002	Dasypus novemcinctus	87.05	0.00e+00	1864.00
IUUC-Dor-030207	Dipodomys ordii	75.91	0.00e+00	1521.00
IUUC-Dse-031531	Dothistroma septosporum	24.50	6.00e-54	206.00
IUUC-Dme-031910	Drosophila melanogaster	34.84	0.00e+00	684.00
IUUC-Ete-033162	Echinops telfairi	82.44	0.00e+00	1351.00
IUUC-Eca-033454	Equus caballus	87.87	0.00e+00	3091.00
IUUC-Eeu-034783	Erinaceus europaeus	72.71	0.00e+00	1430.00
IUUC-Fca-036588	Felis catus	88.79	0.00e+00	3105.00
IUUC-Fal-036919	Ficedula albicollis	87.78	0.00e+00	3011.00
IUUC-Fox-037984	Fusarium oxysporum	24.74	4.00e-39	157.00
IUUC-Fso-038463	Fusarium solani	23.93	2.00e-43	172.00
IUUC-Gmo-039698	Gadus morhua	70.51	0.00e+00	1638.00
IUUC-Ggr-040070	Gaeumannomyces graminis	23.66	3.00e-43	171.00
IUUC-Gga-041123	Gallus gallus	89.01	0.00e+00	3138.00
IUUC-Gac-042622	Gasterosteus aculeatus	65.97	0.00e+00	2197.00
IUUC-Gma-043622	Glycine max	29.68	1.00e-25	112.00
IUUC-Ggo-045583	Gorilla gorilla	87.65	0.00e+00	3095.00
IUUC-Hsa-046343	Homo sapiens	89.80	0.00e+00	3150.00
IUUC-Hvu-047626	Hordeum vulgare	28.62	1.00e-27	118.00
IUUC-Itr-048410	Ictidomys tridecemlineatus	47.38	0.00e+00	1580.00
IUUC-Kpa-049088	Komagataella pastoris	23.59	2.00e-47	184.00
IUUC-Lch-049649	Latimeria chalumnae	76.29	0.00e+00	2644.00
IUUC-Lpe-051516	Leersia perrieri	24.59	5.00e-30	127.00
IUUC-Loc-052818	Lepisosteus oculatus	76.04	0.00e+00	2663.00
IUUC-Lma-053059	Leptosphaeria maculans	22.59	3.00e-47	184.00
IUUC-Laf-054142	Loxodonta africana	89.13	0.00e+00	3144.00
IUUC-Mcc-055677	Macaca mulatta	88.77	0.00e+00	3108.00
IUUC-Meu-056204	Macropus eugenii	68.20	0.00e+00	746.00
IUUC-Mor-057051	Magnaporthe oryzae	23.55	4.00e-50	194.00
IUUC-Mpo-057372	Magnaporthe poae	25.53	2.00e-44	174.00
IUUC-Mtr-058538	Medicago truncatula	29.68	4.00e-27	117.00
IUUC-Mla-058963	Melampsora laricipopulina	24.52	3.00e-53	204.00
IUUC-Mga-059698	Meleagris gallopavo	89.42	0.00e+00	3117.00
IUUC-Mvi-060535	Microbotryum violaceum	23.41	2.00e-47	185.00
IUUC-Mmr-060901	Microcebus murinus	86.50	0.00e+00	3028.00
IUUC-Mdo-062014	Monodelphis domestica	91.91	0.00e+00	3241.00
IUUC-Mmu-063699	Mus musculus	86.15	0.00e+00	3024.00
IUUC-Mac-064773	Musa acuminata	31.36	5.00e-27	117.00
IUUC-Mpu-066153	Mustela putorius furo	89.34	0.00e+00	3135.00
IUUC-Mlu-068151	Myotis lucifugus	88.21	0.00e+00	3080.00
IUUC-Nfi-068403	Neosartorya fischeri	23.93	9.00e-54	206.00
IUUC-Ncr-068864	Neurospora crassa	22.88	6.00e-52	199.00
IUUC-Nle-069529	Nomascus leucogenys	89.06	0.00e+00	3130.00
IUUC-Opr-071107	Ochotona princeps	81.73	0.00e+00	1273.00
IUUC-Ont-072189	Oreochromis niloticus	66.31	0.00e+00	2182.00
IUUC-Ocu-074082	Oryctolagus cuniculus	88.29	0.00e+00	3101.00
IUUC-Oba-075295	Oryza barthii	36.46	3.00e-13	71.20
IUUC-Obr-076117	Oryza brachyantha	27.21	2.00e-25	112.00
IUUC-Ogl-077571	Oryza glaberrima	31.62	4.00e-21	97.40
IUUC-Ogu-078497	Oryza glumaepatula	36.46	3.00e-13	71.20
IUUC-Oin-079343	Oryza indica	36.46	3.00e-13	71.20
IUUC-Olo-081056	Oryza longistaminata	27.12	2.00e-15	78.60
IUUC-Ome-081738	Oryza meridionalis	22.97	4.00e-14	74.30
IUUC-Oni-083099	Oryza nivara	36.46	3.00e-13	71.20
IUUC-Opu-083202	Oryza punctata	28.08	3.00e-26	114.00
IUUC-Oru-084471	Oryza rufipogon	36.46	3.00e-13	71.20
IUUC-Osa-085336	Oryza sativa	31.62	6.00e-22	99.40
IUUC-Ola-087460	Oryzias latipes	65.13	0.00e+00	2162.00
IUUC-Olu-087832	Ostreococcus lucimarinus	27.87	7.00e-03	35.80
IUUC-Oga-088432	Otolemur garnettii	88.67	0.00e+00	3135.00
IUUC-Oar-090206	Ovis aries	86.39	0.00e+00	3061.00
IUUC-Ptr-091180	Pan troglodytes	87.81	0.00e+00	3094.00
IUUC-Pan-092375	Papio anubis	88.77	0.00e+00	3122.00
IUUC-Psi-093049	Pelodiscus sinensis	89.98	0.00e+00	3123.00
IUUC-Pma-094152	Petromyzon marinus	52.80	1.00e-138	486.00
IUUC-Pno-094877	Phaeosphaeria nodorum	22.04	2.00e-37	151.00
IUUC-Ppa-095715	Physcomitrella patens	28.90	9.00e-24	106.00
IUUC-Pfo-096524	Poecilia formosa	64.44	0.00e+00	2060.00
IUUC-Pab-097989	Pongo abelii	87.29	0.00e+00	3042.00
IUUC-Pop-099184	Populus trichocarpa	32.98	2.00e-11	62.80
IUUC-Pca-100207	Procavia capensis	74.76	0.00e+00	1183.00
IUUC-Ppe-101802	Prunus persica	28.90	1.00e-25	112.00
IUUC-Pva-102724	Pteropus vampyrus	48.72	0.00e+00	1141.00
IUUC-Pgr-103372	Puccinia graminis	24.09	4.00e-46	180.00
IUUC-Ptt-103878	Puccinia triticina	23.72	4.00e-44	173.00
IUUC-Pte-104174	Pyrenophora teres	22.09	2.00e-30	129.00
IUUC-Pyt-104431	Pyrenophora triticirepentis	22.11	6.00e-47	183.00
IUUC-Rno-105567	Rattus norvegicus	84.57	0.00e+00	2929.00
IUUC-Sce-106272	Saccharomyces cerevisiae	21.25	4.00e-28	120.00
IUUC-Sha-106980	Sarcophilus harrisii	91.49	0.00e+00	3102.00
IUUC-Sja-107980	Schizosaccharomyces japonicus	23.81	2.00e-47	184.00
IUUC-Spo-108183	Schizosaccharomyces pombe	25.45	4.00e-53	204.00
IUUC-Smo-108719	Selaginella moellendorffii	30.82	5.00e-29	124.00
IUUC-Sit-110716	Setaria italica	25.62	2.00e-29	124.00
IUUC-Sly-111701	Solanum lycopersicum	28.57	1.00e-25	112.00
IUUC-Sar-113332	Sorex araneus	81.06	0.00e+00	2055.00
IUUC-Sbi-114577	Sorghum bicolor	29.79	1.00e-29	126.00
IUUC-Sre-115045	Sporisorium reilianum	27.91	1.00e-41	166.00
IUUC-Ssc-115525	Sus scrofa	88.73	0.00e+00	2411.00
IUUC-Tgu-116943	Taeniopygia guttata	89.41	0.00e+00	3137.00
IUUC-Tru-117673	Takifugu rubripes	65.78	0.00e+00	2193.00
IUUC-Tsy-119032	Tarsius syrichta	88.24	0.00e+00	1752.00
IUUC-Tni-119987	Tetraodon nigroviridis	66.40	0.00e+00	2167.00
IUUC-Tca-121077	Theobroma cacao	32.70	5.00e-26	114.00
IUUC-Tre-122137	Trichoderma reesei	24.43	2.00e-59	224.00
IUUC-Tvi-122272	Trichoderma virens	23.02	6.00e-55	209.00
IUUC-Tae-125358	Triticum aestivum	28.42	3.00e-21	97.80
IUUC-Tur-126562	Triticum urartu	27.76	3.00e-27	117.00
IUUC-Tme-127156	Tuber melanosporum	22.63	3.00e-49	191.00
IUUC-Tbe-128103	Tupaia belangeri	82.52	0.00e+00	1187.00
IUUC-Ttr-128253	Tursiops truncatus	83.08	0.00e+00	2880.00
IUUC-Uma-129344	Ustilago maydis	26.48	2.00e-50	194.00
IUUC-Vda-129778	Verticillium dahliae	22.84	2.00e-54	208.00
IUUC-Vpa-130540	Vicugna pacos	83.86	0.00e+00	2755.00
IUUC-Vvi-131290	Vitis vinifera	32.55	5.00e-27	117.00
IUUC-Xtr-132690	Xenopus tropicalis	82.19	0.00e+00	2894.00
IUUC-Xma-133748	Xiphophorus maculatus	64.73	0.00e+00	2036.00
IUUC-Yli-134662	Yarrowia lipolytica	26.64	5.00e-32	133.00
IUUC-Zma-135553	Zea mays	23.23	2.00e-14	75.10

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence