iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mga-059944

UUCD1 version

UUC-MeG-00127

Ensembl Protein ID

ENSMGAP00000002280.1

UniProt Accession

G1MUP8; G1MUP8_MELGA

Protein Name

Uncharacterized protein

Gene Name

SH3RF1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000002651.1	ENSMGAT00000002955.1	ENSMGAP00000002280.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	2.90e-08	33.8	12	53
UBD/SH3	3.40e-48	161.2	440	495

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C++Cle+++   +vlpC+H+f++ Cl  +     ss++e rCP Cr
   Q: 12   CPVCLERLDASAKVLPCQHTFCKRCLLGI----VSSRNELRCPECR 53
           **********9**************9777....89**********8 PP

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekl 62
           + +++y+y++ ++deL+l+kG++ lv  + +   gW kg++  + k G+fP n+v+ +
   Q: 440  VYIAIYPYTPRKEDELELRKGEMFLVF-ERC-QDGWFKGTSMHTSKIGVFPGNYVAPA 495
           5789**********************9.555.569********************876 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

MDESALLDLL ECPVCLERLD ASAKVLPCQH TFCKRCLLGI VSSRNELRCP ECRTLVDCSV 60
DELPSNILLV RLLDGIKQRP RKPGTVGGTG GANNLRVPIT ANCGSKDLQS SQAGQQQRVQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGATGAAT CAGCTCTGCT GGATCTGTTG GAGTGCCCTG TGTGCTTGGA GCGCCTCGAT 60
GCCTCGGCGA AAGTCTTGCC TTGCCAACAC ACGTTCTGCA AACGCTGCCT GCTGGGTATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001452--SH3_domain
IPR028502--SH3RF1
IPR018957--Znf_C3HC4_RING-type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50002--SH3
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00018--SH3_1
PF14604--SH3_9
PF00097--zf-C3HC4

PRINTS

PR00452--SH3DOMAIN

SMART

SM00184--RING
SM00326--SH3

Gene Ontology

GO:0005829--C:cytosol
GO:0008270--F:zinc ion binding
GO:0006915--P:apoptotic process
GO:0043154--P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:2001237--P:negative regulation of extrinsic apoptotic signaling pathway
GO:0046328--P:regulation of JNK cascade

KEGG

mgp:100539395

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001528	Ailuropoda melanoleuca	79.02	0.00e+00	1155.00
IUUC-Apl-003961	Anas platyrhynchos	93.24	0.00e+00	1393.00
IUUC-Aca-004386	Anolis carolinensis	81.74	0.00e+00	1263.00
IUUC-Ame-010659	Astyanax mexicanus	61.26	0.00e+00	915.00
IUUC-Bta-012563	Bos taurus	60.67	1.00e-114	406.00
IUUC-Cja-019730	Callithrix jacchus	76.29	0.00e+00	1124.00
IUUC-Cfa-020992	Canis familiaris	77.55	0.00e+00	1178.00
IUUC-Cpo-021304	Cavia porcellus	76.60	0.00e+00	1197.00
IUUC-Csa-023925	Chlorocebus sabaeus	76.24	0.00e+00	1143.00
IUUC-Cho-024630	Choloepus hoffmanni	69.05	0.00e+00	737.00
IUUC-Cin-025274	Ciona intestinalis	46.50	2.00e-73	268.00
IUUC-Csv-026136	Ciona savignyi	44.38	1.00e-73	269.00
IUUC-Cme-027278	Cyanidioschyzon merolae	42.55	2.00e-08	53.90
IUUC-Dre-028290	Danio rerio	62.93	0.00e+00	934.00
IUUC-Dno-029083	Dasypus novemcinctus	81.85	0.00e+00	907.00
IUUC-Dor-030388	Dipodomys ordii	85.92	9.00e-171	593.00
IUUC-Dme-032207	Drosophila melanogaster	43.93	6.00e-66	245.00
IUUC-Ete-032809	Echinops telfairi	69.28	0.00e+00	731.00
IUUC-Eca-034185	Equus caballus	77.41	0.00e+00	975.00
IUUC-Eeu-034816	Erinaceus europaeus	67.26	0.00e+00	974.00
IUUC-Fca-036439	Felis catus	75.08	0.00e+00	1185.00
IUUC-Fal-037074	Ficedula albicollis	91.18	0.00e+00	1333.00
IUUC-Gmo-039443	Gadus morhua	60.75	1.00e-117	417.00
IUUC-Ggr-040119	Gaeumannomyces graminis	41.38	8.00e-12	66.20
IUUC-Gga-040749	Gallus gallus	97.94	0.00e+00	1367.00
IUUC-Gac-041420	Gasterosteus aculeatus	63.67	0.00e+00	674.00
IUUC-Ggo-045215	Gorilla gorilla	76.55	0.00e+00	1161.00
IUUC-Hsa-046315	Homo sapiens	76.46	0.00e+00	1154.00
IUUC-Itr-048265	Ictidomys tridecemlineatus	71.07	7.00e-125	439.00
IUUC-Lch-049453	Latimeria chalumnae	73.94	0.00e+00	924.00
IUUC-Loc-052248	Lepisosteus oculatus	37.59	4.00e-78	285.00
IUUC-Laf-053651	Loxodonta africana	78.03	0.00e+00	1145.00
IUUC-Mcc-054688	Macaca mulatta	75.84	0.00e+00	1159.00
IUUC-Meu-056291	Macropus eugenii	73.20	0.00e+00	757.00
IUUC-Mor-056932	Magnaporthe oryzae	40.00	5.00e-12	66.60
IUUC-Mpo-057322	Magnaporthe poae	41.38	7.00e-12	66.20
IUUC-Mmr-061553	Microcebus murinus	75.96	0.00e+00	1096.00
IUUC-Mdo-062313	Monodelphis domestica	76.05	0.00e+00	1159.00
IUUC-Mmu-063516	Mus musculus	77.13	0.00e+00	1187.00
IUUC-Mpu-066064	Mustela putorius furo	77.50	0.00e+00	1158.00
IUUC-Mlu-067312	Myotis lucifugus	80.74	0.00e+00	887.00
IUUC-Nle-069035	Nomascus leucogenys	76.44	0.00e+00	1160.00
IUUC-Opr-070690	Ochotona princeps	71.71	4.00e-159	554.00
IUUC-Ont-071484	Oreochromis niloticus	60.46	0.00e+00	888.00
IUUC-Oan-073305	Ornithorhynchus anatinus	79.20	0.00e+00	1190.00
IUUC-Ocu-074936	Oryctolagus cuniculus	74.42	0.00e+00	1165.00
IUUC-Ola-086675	Oryzias latipes	60.26	0.00e+00	632.00
IUUC-Oga-087933	Otolemur garnettii	71.60	0.00e+00	915.00
IUUC-Oar-090408	Ovis aries	66.89	0.00e+00	724.00
IUUC-Ptr-090865	Pan troglodytes	76.69	0.00e+00	1161.00
IUUC-Pan-092362	Papio anubis	76.24	0.00e+00	1143.00
IUUC-Psi-093876	Pelodiscus sinensis	84.82	0.00e+00	1272.00
IUUC-Pfo-097116	Poecilia formosa	61.62	0.00e+00	905.00
IUUC-Pab-098127	Pongo abelii	76.69	0.00e+00	1159.00
IUUC-Pca-100485	Procavia capensis	79.87	0.00e+00	878.00
IUUC-Pva-102661	Pteropus vampyrus	75.08	0.00e+00	1103.00
IUUC-Rno-105728	Rattus norvegicus	76.87	0.00e+00	1152.00
IUUC-Sha-106515	Sarcophilus harrisii	83.45	0.00e+00	838.00
IUUC-Sar-113161	Sorex araneus	86.52	1.00e-167	583.00
IUUC-Ssc-115314	Sus scrofa	79.90	0.00e+00	834.00
IUUC-Tgu-117012	Taeniopygia guttata	91.07	0.00e+00	1357.00
IUUC-Tru-118467	Takifugu rubripes	63.07	2.00e-170	592.00
IUUC-Tsy-119566	Tarsius syrichta	75.41	4.00e-157	548.00
IUUC-Tni-120830	Tetraodon nigroviridis	56.57	1.00e-178	619.00
IUUC-Tbe-128070	Tupaia belangeri	88.04	2.00e-180	625.00
IUUC-Ttr-128161	Tursiops truncatus	85.88	2.00e-126	446.00
IUUC-Xtr-132628	Xenopus tropicalis	72.39	0.00e+00	1074.00
IUUC-Xma-133732	Xiphophorus maculatus	62.50	0.00e+00	913.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence