iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

UUCD2 ID

IUUC-Rno-105170

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Ring finger protein 180

Genbank Nucleotide ID

AABR07007937

Gene Name

Rnf180

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSRNOG00000043329.3	ENSRNOT00000066069.3	ENSRNOP00000059648.3

Annotation

mRNA Expression
ArrayExpress
DNA & RNA Element
RAID2
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	79.97	0.00e+00	914.00	IUUC-Hsa-045752

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MRRSEESTGT QSSEEQTGAL RCWRCRKCIA SSGCFMSPLE TQAVEDDLDH SLSPQNTCHL 60
WPHEHRTLPA WLTIVVPEAQ WTVGKLNCPF CGARLGGFNF VSTPKCSCGQ LAAVHLCKSR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAGAAGAA GTGAAGAGTC GACAGGCACG CAGAGCAGTG AGGAGCAGAC AGGAGCCCTT 60
CGTTGCTGGA GATGTAGAAA ATGCATCGCA AGTTCTGGTT GCTTCATGAG TCCTCTTGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR033263--RNF180
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2

SMART

SM00184--RING

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0005622--C:intracellular
GO:0031227--C:intrinsic component of endoplasmic reticulum membrane
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0030534--P:adult behavior
GO:0042415--P:norepinephrine metabolic process
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0031398--P:positive regulation of protein ubiquitination
GO:0000209--P:protein polyubiquitination
GO:0050790--P:regulation of catalytic activity
GO:0042428--P:serotonin metabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002250	Ailuropoda melanoleuca	74.78	0.00e+00	851.00
IUUC-Apl-003598	Anas platyrhynchos	48.61	4.00e-134	471.00
IUUC-Aca-004364	Anolis carolinensis	44.41	1.00e-126	446.00
IUUC-Ame-011498	Astyanax mexicanus	70.44	9.00e-68	249.00
IUUC-Bta-012990	Bos taurus	74.27	0.00e+00	855.00
IUUC-Bci-013759	Botrytis cinerea	32.05	6.00e-06	45.40
IUUC-Cja-019420	Callithrix jacchus	79.27	0.00e+00	907.00
IUUC-Cfa-020028	Canis familiaris	75.99	0.00e+00	869.00
IUUC-Cpo-021698	Cavia porcellus	70.16	0.00e+00	667.00
IUUC-Csa-023637	Chlorocebus sabaeus	78.76	0.00e+00	899.00
IUUC-Cho-025073	Choloepus hoffmanni	62.28	0.00e+00	674.00
IUUC-Dre-027523	Danio rerio	71.71	3.00e-68	251.00
IUUC-Dno-030040	Dasypus novemcinctus	68.25	1.00e-178	619.00
IUUC-Dor-030405	Dipodomys ordii	76.72	0.00e+00	858.00
IUUC-Eca-033366	Equus caballus	77.55	0.00e+00	903.00
IUUC-Fca-035526	Felis catus	80.98	0.00e+00	716.00
IUUC-Fal-037590	Ficedula albicollis	46.31	3.00e-130	458.00
IUUC-Gmo-039484	Gadus morhua	51.97	1.00e-42	167.00
IUUC-Gga-040136	Gallus gallus	47.54	5.00e-139	488.00
IUUC-Gac-041811	Gasterosteus aculeatus	51.59	2.00e-41	163.00
IUUC-Ggo-044673	Gorilla gorilla	79.27	0.00e+00	916.00
IUUC-Hsa-045752	Homo sapiens	79.97	0.00e+00	922.00
IUUC-Itr-047971	Ictidomys tridecemlineatus	77.89	0.00e+00	907.00
IUUC-Lch-050309	Latimeria chalumnae	45.21	3.00e-117	415.00
IUUC-Loc-052203	Lepisosteus oculatus	42.76	2.00e-108	386.00
IUUC-Laf-053398	Loxodonta africana	74.27	0.00e+00	848.00
IUUC-Mcc-054745	Macaca mulatta	80.83	0.00e+00	933.00
IUUC-Mmr-060583	Microcebus murinus	79.27	0.00e+00	928.00
IUUC-Mdo-062873	Monodelphis domestica	60.07	0.00e+00	680.00
IUUC-Mmu-063393	Mus musculus	88.07	0.00e+00	857.00
IUUC-Mac-065655	Musa acuminata	27.50	1.00e-07	50.40
IUUC-Mpu-066186	Mustela putorius furo	72.93	0.00e+00	850.00
IUUC-Mlu-068079	Myotis lucifugus	74.01	0.00e+00	845.00
IUUC-Nle-069164	Nomascus leucogenys	80.31	0.00e+00	928.00
IUUC-Opr-070362	Ochotona princeps	69.43	0.00e+00	741.00
IUUC-Oan-073509	Ornithorhynchus anatinus	48.44	3.00e-52	198.00
IUUC-Ocu-073894	Oryctolagus cuniculus	65.70	1.00e-171	596.00
IUUC-Oga-088485	Otolemur garnettii	78.41	0.00e+00	889.00
IUUC-Oar-089831	Ovis aries	72.71	0.00e+00	855.00
IUUC-Ptr-091570	Pan troglodytes	80.14	0.00e+00	926.00
IUUC-Psi-093962	Pelodiscus sinensis	50.43	2.00e-156	545.00
IUUC-Pfo-096369	Poecilia formosa	67.92	2.00e-62	232.00
IUUC-Pab-098224	Pongo abelii	65.11	0.00e+00	684.00
IUUC-Pca-100186	Procavia capensis	71.68	0.00e+00	773.00
IUUC-Pva-102511	Pteropus vampyrus	77.03	0.00e+00	904.00
IUUC-Sha-107501	Sarcophilus harrisii	63.86	0.00e+00	633.00
IUUC-Ssc-115668	Sus scrofa	72.16	0.00e+00	765.00
IUUC-Tgu-117098	Taeniopygia guttata	47.26	3.00e-126	445.00
IUUC-Tru-118625	Takifugu rubripes	70.75	7.00e-62	229.00
IUUC-Tsy-118959	Tarsius syrichta	76.68	0.00e+00	870.00
IUUC-Tni-120324	Tetraodon nigroviridis	34.02	2.00e-32	133.00
IUUC-Tbe-127448	Tupaia belangeri	81.04	0.00e+00	806.00
IUUC-Ttr-128470	Tursiops truncatus	73.92	0.00e+00	815.00
IUUC-Vpa-130097	Vicugna pacos	76.74	0.00e+00	808.00
IUUC-Xtr-132848	Xenopus tropicalis	40.75	5.00e-101	361.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence