iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
TRANSFAC	RAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
dbPAF
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	1.50e-13	51.3	37	100

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkld 66
           +D++l+v++++f+ahk+ LaasS++F+ +f  e e +  ++ + ++++ ++ f  ll+F+Ytg l 
   Q: 37   CDITLIVENVHFRAHKALLAASSEYFSMMFAEEGEIG--QSIYMLEGMVADTFGILLEFIYTGYLH 100
           8*****************************7766665..57777888****************886 PP

Organism

Rattus norvegicus

Functional Description
(View)

May be involved in BMP2-induced transcription.

Protein Sequence
(Fasta)

MADTTPEPSG HLIVHSDTHS DTVLASLEDQ RKKGFLCDIT LIVENVHFRA HKALLAASSE 60
YFSMMFAEEG EIGQSIYMLE GMVADTFGIL LEFIYTGYLH ASEKMTEQIL ATAQFLKVYD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGCGCGCGCT TCCGGGCTGA CAGTCGCCGG GAGCCGGGAG CTTACGCGCA GTGGTGCCGG 60
GGGCGTGGAT CGGCGACAGG CCCGGCTTGG TGTCCTCTGG GCAGCCCGGT GGACTGACTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0238--DNA-binding
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR000210--BTB/POZ_dom
IPR023413--GFP-like
IPR011333--SKP1/BTB/POZ
IPR013087--Znf_C2H2_type
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50097--BTB
PS00028--ZINC_FINGER_C2H2_1
PS50157--ZINC_FINGER_C2H2_2

Pfam

PF00651--BTB

SMART

SM00225--BTB
SM00355--ZnF_C2H2

Gene Ontology

GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:0046872--F:metal ion binding
GO:0003700--F:transcription factor activity, sequence-specific DNA binding
GO:0002244--P:hematopoietic progenitor cell differentiation
GO:0006355--P:regulation of transcription, DNA-templated
GO:0006351--P:transcription, DNA-templated

KEGG

rno:365590

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001722	Ailuropoda melanoleuca	79.77	0.00e+00	1034.00
IUUC-Apl-003854	Anas platyrhynchos	72.25	0.00e+00	846.00
IUUC-Ame-011090	Astyanax mexicanus	48.93	3.00e-161	562.00
IUUC-Bta-013015	Bos taurus	82.63	0.00e+00	1022.00
IUUC-Cja-019537	Callithrix jacchus	82.54	0.00e+00	1055.00
IUUC-Cfa-021048	Canis familiaris	80.85	0.00e+00	1045.00
IUUC-Cpo-021818	Cavia porcellus	84.93	0.00e+00	1065.00
IUUC-Csa-023709	Chlorocebus sabaeus	85.30	0.00e+00	1053.00
IUUC-Cho-024967	Choloepus hoffmanni	78.20	0.00e+00	909.00
IUUC-Csv-025932	Ciona savignyi	26.68	5.00e-39	155.00
IUUC-Dre-028277	Danio rerio	45.41	1.00e-150	526.00
IUUC-Dno-029444	Dasypus novemcinctus	83.67	0.00e+00	1069.00
IUUC-Dor-030792	Dipodomys ordii	84.49	0.00e+00	1101.00
IUUC-Ete-032398	Echinops telfairi	75.86	0.00e+00	872.00
IUUC-Eca-034254	Equus caballus	86.00	0.00e+00	1062.00
IUUC-Fca-035831	Felis catus	81.69	0.00e+00	983.00
IUUC-Fal-037055	Ficedula albicollis	69.75	0.00e+00	782.00
IUUC-Gmo-039469	Gadus morhua	45.26	2.00e-142	499.00
IUUC-Gga-040581	Gallus gallus	69.77	0.00e+00	863.00
IUUC-Gac-041537	Gasterosteus aculeatus	48.68	8.00e-152	530.00
IUUC-Ggo-045494	Gorilla gorilla	85.82	0.00e+00	1059.00
IUUC-Hsa-045793	Homo sapiens	86.13	0.00e+00	1061.00
IUUC-Itr-048173	Ictidomys tridecemlineatus	86.78	0.00e+00	1081.00
IUUC-Lch-050497	Latimeria chalumnae	55.35	1.00e-131	462.00
IUUC-Loc-052654	Lepisosteus oculatus	60.19	3.00e-148	518.00
IUUC-Laf-053350	Loxodonta africana	83.61	0.00e+00	1052.00
IUUC-Mcc-055866	Macaca mulatta	85.26	0.00e+00	1061.00
IUUC-Meu-056118	Macropus eugenii	67.49	7.00e-107	381.00
IUUC-Mga-060047	Meleagris gallopavo	69.66	0.00e+00	858.00
IUUC-Mmr-060588	Microcebus murinus	81.20	0.00e+00	1001.00
IUUC-Mdo-062336	Monodelphis domestica	75.42	0.00e+00	954.00
IUUC-Mmu-063926	Mus musculus	91.03	0.00e+00	1285.00
IUUC-Mpu-066822	Mustela putorius furo	81.94	0.00e+00	1008.00
IUUC-Mlu-067720	Myotis lucifugus	84.27	0.00e+00	1030.00
IUUC-Nle-070056	Nomascus leucogenys	86.28	0.00e+00	1059.00
IUUC-Opr-070424	Ochotona princeps	74.92	0.00e+00	910.00
IUUC-Ont-072021	Oreochromis niloticus	48.86	3.00e-165	575.00
IUUC-Oan-073359	Ornithorhynchus anatinus	76.62	1.00e-88	320.00
IUUC-Ocu-074138	Oryctolagus cuniculus	82.05	0.00e+00	1010.00
IUUC-Oga-088106	Otolemur garnettii	83.94	0.00e+00	1039.00
IUUC-Oar-089235	Ovis aries	85.80	0.00e+00	1106.00
IUUC-Ptr-090645	Pan troglodytes	85.98	0.00e+00	1059.00
IUUC-Pan-092161	Papio anubis	84.50	0.00e+00	1046.00
IUUC-Psi-093172	Pelodiscus sinensis	70.62	0.00e+00	849.00
IUUC-Pfo-096250	Poecilia formosa	55.09	1.00e-126	446.00
IUUC-Pab-098359	Pongo abelii	85.82	0.00e+00	1053.00
IUUC-Pva-103156	Pteropus vampyrus	85.69	0.00e+00	1100.00
IUUC-Sha-107110	Sarcophilus harrisii	73.03	0.00e+00	914.00
IUUC-Sar-113684	Sorex araneus	79.83	0.00e+00	1035.00
IUUC-Ssc-115999	Sus scrofa	86.30	0.00e+00	1107.00
IUUC-Tgu-116975	Taeniopygia guttata	70.91	0.00e+00	801.00
IUUC-Tru-117553	Takifugu rubripes	48.09	1.00e-155	543.00
IUUC-Tsy-119107	Tarsius syrichta	88.39	8.00e-167	580.00
IUUC-Tni-120348	Tetraodon nigroviridis	48.21	5.00e-142	498.00
IUUC-Tbe-127729	Tupaia belangeri	82.99	0.00e+00	1085.00
IUUC-Ttr-129257	Tursiops truncatus	86.76	0.00e+00	1093.00
IUUC-Vpa-130203	Vicugna pacos	84.63	0.00e+00	1057.00
IUUC-Xtr-131980	Xenopus tropicalis	42.75	9.00e-108	383.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence