iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cfa-020493

Ensembl Protein ID

ENSCAFP00000041935.1

UniProt Accession

J9P868; J9P868_CANLF

Genbank Protein ID

ENSCAFP00000041935

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03006765

Gene Name

NACC2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000030397.1	ENSCAFT00000043972.1	ENSCAFP00000041935.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	5.70e-16	59.0	30	92

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikd.vqpevfrallkFlYtgklde 67
           +Dv +vv+g+ f+ah++vLaasS +F++lf+++     sk+  e+ + v p +f+++l+F+Ytg+l++
   Q: 30   CDVSIVVKGQAFKAHRAVLAASSLYFRDLFSGN-----SKSAFELPGtVPPACFQQILSFCYTGRLTM 92
           8*****************************774.....46778***88*****************986 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MSQMLHIEIP NFGNTVLGCL NEQRLLGLYC DVSIVVKGQA FKAHRAVLAA SSLYFRDLFS 60
GNSKSAFELP GTVPPACFQQ ILSFCYTGRL TMAASEQLVV MYTAGFLQIQ HIVERGTDLM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTGCCCCT CTCGGGCGCT CCCGCGCTGA GTCTGAGGCG AGCCCTCTAG CGCCTGCCCG 60
CCATGTCGCA GATGCTACAC ATCGAGATCC CCAACTTCGG GAACACCGTG CTCGGCTGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR018379--BEN_domain
IPR000210--BTB/POZ_dom
IPR011333--SKP1/BTB/POZ

PROSITE

PS51457--BEN
PS50097--BTB

Pfam

PF10523--BEN
PF00651--BTB

SMART

SM01025--BEN
SM00225--BTB

Gene Ontology

GO:0005739--C:mitochondrion
GO:0000790--C:nuclear chromatin
GO:0005730--C:nucleolus
GO:0016581--C:NuRD complex
GO:0004407--F:histone deacetylase activity
GO:0000978--F:RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001076--F:transcription factor activity, RNA polymerase II transcription factor binding
GO:0001078--F:transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0034629--P:cellular protein complex localization
GO:0008285--P:negative regulation of cell proliferation
GO:1900477--P:negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter
GO:1902231--P:positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage
GO:0010608--P:posttranscriptional regulation of gene expression
GO:0051260--P:protein homooligomerization

KEGG

cfa:491255

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001902	Ailuropoda melanoleuca	98.07	8.00e-132	463.00
IUUC-Apl-004203	Anas platyrhynchos	83.77	2.00e-167	582.00
IUUC-Ame-011046	Astyanax mexicanus	60.40	2.00e-88	319.00
IUUC-Bta-012908	Bos taurus	93.60	2.00e-170	592.00
IUUC-Cja-019140	Callithrix jacchus	93.06	0.00e+00	638.00
IUUC-Cpo-022399	Cavia porcellus	90.49	1.00e-180	626.00
IUUC-Csa-024135	Chlorocebus sabaeus	94.74	3.00e-177	614.00
IUUC-Dre-027761	Danio rerio	61.28	1.00e-135	476.00
IUUC-Dno-029271	Dasypus novemcinctus	77.81	8.00e-118	417.00
IUUC-Ete-032427	Echinops telfairi	85.06	8.00e-150	523.00
IUUC-Eca-033986	Equus caballus	93.31	1.00e-176	613.00
IUUC-Eeu-035211	Erinaceus europaeus	91.88	2.00e-171	595.00
IUUC-Fca-035733	Felis catus	95.35	1.00e-152	533.00
IUUC-Fal-037348	Ficedula albicollis	82.32	4.00e-163	568.00
IUUC-Gmo-039529	Gadus morhua	82.44	2.00e-94	339.00
IUUC-Gga-040405	Gallus gallus	82.90	3.00e-165	575.00
IUUC-Gac-041308	Gasterosteus aculeatus	80.54	2.00e-102	365.00
IUUC-Ggo-044687	Gorilla gorilla	97.54	7.00e-141	494.00
IUUC-Hsa-045955	Homo sapiens	96.74	6.00e-172	597.00
IUUC-Itr-048872	Ictidomys tridecemlineatus	94.38	2.00e-168	585.00
IUUC-Lch-049615	Latimeria chalumnae	74.43	2.00e-150	525.00
IUUC-Loc-051881	Lepisosteus oculatus	79.10	3.00e-119	422.00
IUUC-Lma-053325	Leptosphaeria maculans	35.09	2.00e-06	45.80
IUUC-Laf-054170	Loxodonta africana	84.70	4.00e-150	525.00
IUUC-Mga-059627	Meleagris gallopavo	82.90	2.00e-165	575.00
IUUC-Mdo-063014	Monodelphis domestica	89.38	0.00e+00	851.00
IUUC-Mmu-063897	Mus musculus	90.14	4.00e-178	617.00
IUUC-Mpu-066806	Mustela putorius furo	95.64	1.00e-162	566.00
IUUC-Nle-069114	Nomascus leucogenys	95.36	2.00e-178	618.00
IUUC-Opr-071127	Ochotona princeps	94.26	3.00e-66	246.00
IUUC-Ont-071693	Oreochromis niloticus	79.65	1.00e-105	376.00
IUUC-Oan-073510	Ornithorhynchus anatinus	86.96	4.00e-174	604.00
IUUC-Ola-086572	Oryzias latipes	72.62	9.00e-111	394.00
IUUC-Oga-088653	Otolemur garnettii	91.01	1.00e-178	619.00
IUUC-Oar-089811	Ovis aries	93.58	1.00e-139	489.00
IUUC-Ptr-090703	Pan troglodytes	96.74	2.00e-171	595.00
IUUC-Pan-092388	Papio anubis	91.98	0.00e+00	633.00
IUUC-Psi-093786	Pelodiscus sinensis	83.77	3.00e-168	585.00
IUUC-Pma-094566	Petromyzon marinus	72.63	2.00e-64	239.00
IUUC-Pfo-096554	Poecilia formosa	70.07	4.00e-109	388.00
IUUC-Pca-101090	Procavia capensis	89.12	3.00e-162	565.00
IUUC-Pva-102843	Pteropus vampyrus	92.73	1.00e-176	613.00
IUUC-Rno-105139	Rattus norvegicus	88.44	5.00e-178	617.00
IUUC-Sha-107545	Sarcophilus harrisii	87.28	3.00e-173	602.00
IUUC-Tgu-117401	Taeniopygia guttata	84.06	5.00e-167	580.00
IUUC-Tru-118080	Takifugu rubripes	78.67	6.00e-96	344.00
IUUC-Tni-120321	Tetraodon nigroviridis	73.33	2.00e-99	355.00
IUUC-Ttr-128369	Tursiops truncatus	96.59	8.00e-95	340.00
IUUC-Xtr-131793	Xenopus tropicalis	96.72	1.00e-68	253.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence