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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Hsa-046491
UUCD1 version UUC-HoS-00865
Ensembl Protein ID ENSP00000376572.1
UniProt Accession Q9H0X6; A2BFA0; RN208_HUMAN
Genbank Protein ID CAB66475.1; AAL16809.1; AAH16958.1
Protein Name RING finger protein 208
Genbank Nucleotide ID BX255925; AF416715; BC016958
Gene Name RNF208
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000212864.3 ENST00000392827.2 ENSP00000376572.1
Annotation
Cancer Mutation
TCGAICGCCOSMICCGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressTCGAICGC
COSMICTHPA
DNA & RNA Element
microRNATRANSFACTargetScanRepTar
SomamiRmiRcodeRAID2
Protein-protein Interaction
IIDiRefIndexHINTMentha
InWeb_IM
Post-translational Modifications (PTMs)
dbPAFPhosphositePlusdbPTMUniProt
DNA Methylation
TCGAICGCCOSMIC
Protein Expression/Proteomics
THPAGPMDB
Status Reviewed
Details
Family Domain References (PMIDs)
E3 activity/RING/RING RING 24105792
Classification
Family E-value Score Start End
E3 activity/RING/RING 3.30e-05 26.0 143 190
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/RING
   S: 1    CaiCledf...kdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C++C  ++   ++ p+vl+C H  +++Clq + + ++ ++k+++CP+Cr
   Q: 143  CPTCGHSYnvtQRRPRVLSCLHSVCEQCLQIL-YESCPKYKFISCPTCR 190
           ****9999999555***************999.99999**********8 PP
   
Organism Homo sapiens
Protein Sequence
(Fasta)
MPSDPGPEAG SGWPGLLMSC LKGPHVILKM EAMKIVHPEK FPELPAAPCF PPAPRPTPTL 60
APKRAWPSDT EIIVNQACGG DMPALEGAPH TPPLPRRPRK GSSELGFPRV APEDEVIVNQ 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Hsa-046491|E3,RING|Homo sapiens
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GGCCTGCTGA CCTCGGCTGC AGGGGGAGCC CCCCCCGCGC CCCCTCGCCA GCCTCAGCAG 60
CCAGAGACCC TGGGTGAGAC CCTGGGCCAG ACCCCCAGCC CAGGGCAGCC TCCCACCCCT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Hsa-046491|E3,RING|Homo sapiens
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2
Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0051865--P:protein autoubiquitination
KEGG hsa:727800
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Apl-003578 Anas platyrhynchos 63.39 3.00e-84 304.00
IUUC-Ame-011826 Astyanax mexicanus 51.10 4.00e-60 224.00
IUUC-Bta-012546 Bos taurus 82.71 9.00e-118 416.00
IUUC-Cfa-020443 Canis familiaris 85.28 7.00e-114 403.00
IUUC-Csa-023189 Chlorocebus sabaeus 99.23 3.00e-127 447.00
IUUC-Dre-027549 Danio rerio 54.72 1.00e-62 232.00
IUUC-Dno-029779 Dasypus novemcinctus 87.36 4.00e-122 430.00
IUUC-Dor-030838 Dipodomys ordii 99.02 1.00e-55 209.00
IUUC-Ete-033179 Echinops telfairi 89.44 3.00e-87 313.00
IUUC-Eeu-034856 Erinaceus europaeus 91.46 6.00e-79 286.00
IUUC-Fca-036599 Felis catus 84.53 5.00e-112 397.00
IUUC-Fal-036880 Ficedula albicollis 65.62 2.00e-86 311.00
IUUC-Gmo-038843 Gadus morhua 71.81 4.00e-57 213.00
IUUC-Gga-040602 Gallus gallus 61.51 2.00e-83 301.00
IUUC-Gac-042541 Gasterosteus aculeatus 59.04 8.00e-57 212.00
IUUC-Ggo-045325 Gorilla gorilla 100.00 7.00e-128 449.00
IUUC-Hvu-047109 Hordeum vulgare 38.98 5.00e-06 45.10
IUUC-Itr-048264 Ictidomys tridecemlineatus 86.89 2.00e-119 421.00
IUUC-Lch-050212 Latimeria chalumnae 60.23 3.00e-80 291.00
IUUC-Loc-052420 Lepisosteus oculatus 56.05 5.00e-60 223.00
IUUC-Laf-053629 Loxodonta africana 87.90 2.00e-110 391.00
IUUC-Mcc-055025 Macaca mulatta 98.85 6.00e-136 476.00
IUUC-Meu-055903 Macropus eugenii 79.39 1.00e-105 375.00
IUUC-Mga-059611 Meleagris gallopavo 73.01 3.00e-65 240.00
IUUC-Mmr-061478 Microcebus murinus 93.94 7.00e-129 452.00
IUUC-Mdo-062349 Monodelphis domestica 85.56 1.00e-78 285.00
IUUC-Mmu-063251 Mus musculus 88.30 9.00e-116 409.00
IUUC-Mpu-066126 Mustela putorius furo 85.66 4.00e-121 427.00
IUUC-Oga-088531 Otolemur garnettii 87.97 3.00e-121 427.00
IUUC-Pan-091686 Papio anubis 99.23 3.00e-127 447.00
IUUC-Pfo-097328 Poecilia formosa 51.49 1.00e-58 219.00
IUUC-Pab-097541 Pongo abelii 99.62 1.00e-127 448.00
IUUC-Pca-100264 Procavia capensis 87.02 3.00e-124 437.00
IUUC-Pva-102345 Pteropus vampyrus 86.42 4.00e-115 407.00
IUUC-Rno-106092 Rattus norvegicus 88.30 9.00e-116 409.00
IUUC-Sha-106509 Sarcophilus harrisii 79.39 1.00e-105 375.00
IUUC-Sit-110791 Setaria italica 36.67 3.00e-06 45.40
IUUC-Sbi-114208 Sorghum bicolor 36.67 3.00e-06 45.40
IUUC-Ssc-115802 Sus scrofa 85.66 9.00e-112 396.00
IUUC-Tru-117537 Takifugu rubripes 54.80 2.00e-61 228.00
IUUC-Ttr-128327 Tursiops truncatus 86.79 2.00e-122 431.00
IUUC-Xtr-132106 Xenopus tropicalis 63.85 2.00e-84 305.00
IUUC-Xma-133724 Xiphophorus maculatus 51.49 1.00e-58 219.00
Created Date 25-Jun-2017

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