iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ggo-044569

Ensembl Protein ID

ENSGGOP00000020532.1

UniProt Accession

G3RXJ6; G3RXJ6_GORGO

Protein Name

Uncharacterized protein

Gene Name

ARHGAP10

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000014936.2	ENSGGOT00000034724.1	ENSGGOP00000020532.1
ENSGGOG00000014936.2	ENSGGOT00000014992.2	ENSGGOP00000014579.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	3.50e-11	43.3	682	736

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 4    ekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
           +k ++ y+ ea+++ eL+++ G + + + +++ + gWl+g  +l+gkrGl+P+n+v+ 
   Q: 682  RKARAVYPCEAEHSSELSFEIGAIFEDV-QTSREPGWLEG--TLNGKRGLIPQNYVKL 736
           67899***********************.***********..8*************85 PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

IILLFLGLSV AQRKFAHSLR DFKFEFIGDA VTDDERCIDA SLREFSNFLK NLEEQREIMA 60
LSVTETLIKP LEKFRKEQLG AVKEEKKKFD KETEKNYSLI DKHLNLSAKK KDSHLQEADI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATTATACTTT TGTTTCTAGG TCTGTCAGTG GCCCAGCGGA AGTTTGCTCA TTCACTCAGA 60
GACTTTAAGT TTGAGTTTAT CGGTGATGCT GTGACAGATG ATGAACGATG CATAGGTAAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0343--GTPase activation
KW-1185--Reference proteome

Interpro

IPR027267--AH/BAR-dom
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR008936--Rho_GTPase_activation_prot
IPR000198--RhoGAP_dom
IPR001452--SH3_domain

PROSITE

PS50003--PH_DOMAIN
PS50238--RHOGAP
PS50002--SH3

Pfam

PF00169--PH
PF00620--RhoGAP
PF14604--SH3_9

SMART

SM00233--PH
SM00324--RhoGAP
SM00326--SH3

Gene Ontology

GO:0005829--C:cytosol
GO:0005096--F:GTPase activator activity
GO:0007010--P:cytoskeleton organization
GO:0043066--P:negative regulation of apoptotic process
GO:0007165--P:signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001253	Ailuropoda melanoleuca	90.74	0.00e+00	1319.00
IUUC-Apl-003297	Anas platyrhynchos	77.01	0.00e+00	1105.00
IUUC-Aca-005285	Anolis carolinensis	75.14	0.00e+00	1091.00
IUUC-Bta-012379	Bos taurus	89.78	0.00e+00	1234.00
IUUC-Cja-019182	Callithrix jacchus	93.46	0.00e+00	1347.00
IUUC-Cfa-021141	Canis familiaris	91.01	0.00e+00	1301.00
IUUC-Csa-023847	Chlorocebus sabaeus	95.92	0.00e+00	1365.00
IUUC-Dre-027525	Danio rerio	58.36	0.00e+00	774.00
IUUC-Dno-029215	Dasypus novemcinctus	83.51	0.00e+00	881.00
IUUC-Dor-030308	Dipodomys ordii	80.65	0.00e+00	1119.00
IUUC-Ete-032666	Echinops telfairi	75.98	0.00e+00	726.00
IUUC-Eca-033545	Equus caballus	91.83	0.00e+00	1300.00
IUUC-Fca-036457	Felis catus	90.87	0.00e+00	1314.00
IUUC-Fal-036703	Ficedula albicollis	77.07	0.00e+00	1108.00
IUUC-Gga-040830	Gallus gallus	76.49	0.00e+00	1116.00
IUUC-Gac-041728	Gasterosteus aculeatus	54.63	0.00e+00	728.00
IUUC-Hsa-045658	Homo sapiens	96.73	0.00e+00	1316.00
IUUC-Loc-051740	Lepisosteus oculatus	61.28	0.00e+00	865.00
IUUC-Laf-053641	Loxodonta africana	89.78	0.00e+00	1234.00
IUUC-Mcc-055152	Macaca mulatta	95.64	0.00e+00	1388.00
IUUC-Mga-060152	Meleagris gallopavo	59.48	3.00e-68	251.00
IUUC-Mmr-061434	Microcebus murinus	92.23	0.00e+00	1323.00
IUUC-Mdo-062864	Monodelphis domestica	84.45	0.00e+00	1236.00
IUUC-Mmu-064061	Mus musculus	88.69	0.00e+00	1280.00
IUUC-Mlu-067375	Myotis lucifugus	89.92	0.00e+00	1280.00
IUUC-Nle-069319	Nomascus leucogenys	93.67	0.00e+00	752.00
IUUC-Ont-071443	Oreochromis niloticus	59.57	0.00e+00	805.00
IUUC-Oan-072978	Ornithorhynchus anatinus	80.35	0.00e+00	1060.00
IUUC-Ocu-074591	Oryctolagus cuniculus	86.12	0.00e+00	1242.00
IUUC-Ola-087508	Oryzias latipes	52.73	0.00e+00	739.00
IUUC-Oga-088922	Otolemur garnettii	89.39	0.00e+00	656.00
IUUC-Oar-089531	Ovis aries	90.19	0.00e+00	1251.00
IUUC-Ptr-091149	Pan troglodytes	95.23	0.00e+00	1313.00
IUUC-Pan-092591	Papio anubis	95.91	0.00e+00	1386.00
IUUC-Pma-094731	Petromyzon marinus	32.91	2.00e-17	85.10
IUUC-Pab-097780	Pongo abelii	96.46	0.00e+00	1315.00
IUUC-Rno-104991	Rattus norvegicus	88.01	0.00e+00	1273.00
IUUC-Sha-107629	Sarcophilus harrisii	81.74	0.00e+00	1086.00
IUUC-Ssc-115511	Sus scrofa	73.75	0.00e+00	682.00
IUUC-Tgu-117458	Taeniopygia guttata	75.95	0.00e+00	1099.00
IUUC-Tru-117724	Takifugu rubripes	60.42	0.00e+00	657.00
IUUC-Tbe-128126	Tupaia belangeri	27.81	3.00e-06	47.00
IUUC-Ttr-129045	Tursiops truncatus	87.87	0.00e+00	1222.00
IUUC-Xtr-132112	Xenopus tropicalis	67.43	0.00e+00	966.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence