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Tag Content
UUCD2 ID IUUC-Cfa-021022
UUCD1 version UUC-CaF-00804
Ensembl Protein ID ENSCAFP00000042791.1
UniProt Accession J9NT77; J9NT77_CANLF
Genbank Protein ID ENSCAFP00000042791
Protein Name Uncharacterized protein
Genbank Nucleotide ID AAEX03014712
Gene Name FBXW8
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSCAFG00000009295.4 ENSCAFT00000046460.2 ENSCAFP00000042791.1
ENSCAFG00000009295.4 ENSCAFT00000014770.3 ENSCAFP00000013663.3
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 8.70e-12 45.1 481 510
UBD/Beta-Prp 3.20e-41 141.7 211 513
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 2    HtdsvtclafsdtllvsGsdDgtikvWDlr 31
           H+ +v++++ +d+ +vsG+  g + vWD+r
   Q: 481  HQLGVSAVQMDDWKIVSGGEEGLVSVWDYR 510
           7778999999669***************86 PP
   

   UBD/Beta-Prp
   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkl.....lrslsgheae....vtavkfspdgkilvtgseDrtikvwdlst 83
           +l++ +++v+++v+   ++ ++++g+++g ++vwd++t+++      ++++++e++    v+ v+++++  + v + eD+++++wdl+t
   Q: 211  ELEHIPDAVLCDVHS--HDGVVIAGYTSGDVRVWDTRTWDYtapflESEYEEDEPGmqpyVSFVRINSS--LAVAAYEDGFLNIWDLRT 295
           567778999998888..9***********************7777433334444449999*********..9***************** PP
   S: 84   gkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkl 171
           gk+ ++  +h++++ +l++s+++ +++++s+ +++++   e+g++  + + + +++v ++++ pd+ ++ v+ ++ + + ++ lk ++ 
   Q: 296  GKYPVHRFEHDARIQALALSQEDATVATASAFDVVMLRPNEEGYWQITAEFEVQKLVDYLEIVPDTgRYPVAVATAGDL-VYLLKAEDS 383
           ***999999**************************************9******************************9.5******** PP
   S: 172  lrtltgghtdsvyslsfdsng.....kelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfs.pnderlvsgssDgsiriWdlrsg 254
            rtl     ++v++l+++ n+     k+l ++ + +++ +++l++++c+ +l +    +++v++  +   ++vsg++D+ +ri+dlr++
   Q: 384  ARTLHYVYGQPVTCLDVSANQaafgvKSLGWVYEGNKILVYSLEAERCLSKLGNALGDFTCVNLRnSPPSLMVSGNMDRRVRIHDLRTD 472
           ****999*********************************************************9778899****************** PP
   S: 255  dllktlqlhnssvisvavlsfgdnvlvlgsedskvniwklkkne 298
           ++  +l+ h+  v++v++   +d+++v+g+e++ v +w++++++
   Q: 473  KIALSLSAHQLGVSAVQM---DDWKIVSGGEEGLVSVWDYRMSQ 513
           **********99999999...*******************9876 PP
   
Organism Canis familiaris
Protein Sequence
(Fasta)
MDDHSLDEFR RRWQEELAQA QALRKRRRRR RRPRRRPPRA PAPARLASLP SESENGFPTS 60
AQGLCDLGGG GPPPPPPATA TPPLPPPSRL CGCVTESQVI SGPTLIPSLV LFLNEMDDVP 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Cfa-021022|E3,WD_repeat;UBD,Beta-Prp|Canis familiaris
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGGACGACC ACAGCCTGGA CGAGTTCCGC CGGCGCTGGC AGGAGGAGCT GGCGCAGGCC 60
CAGGCGCTCC GGAAGCGGCG GCGGCACAAA AATGGACTGA ATAGGTATTA TGATGACACT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Cfa-021022|E3,WD_repeat;UBD,Beta-Prp|Canis familiaris
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat
Interpro

IPR001810--F-box_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS50181--FBOX
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF12937--F-box-like
SMART

SM00256--FBOX
SM00320--WD40
Gene Ontology

GO:1990393--C:3M complex
GO:0031467--C:Cul7-RING ubiquitin ligase complex
GO:0005829--C:cytosol
GO:0005794--C:Golgi apparatus
GO:0048471--C:perinuclear region of cytoplasm
GO:0019005--C:SCF ubiquitin ligase complex
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008283--P:cell proliferation
GO:0007030--P:Golgi organization
GO:0060716--P:labyrinthine layer blood vessel development
GO:0050775--P:positive regulation of dendrite morphogenesis
GO:0060712--P:spongiotrophoblast layer development
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001274 Ailuropoda melanoleuca 96.60 0.00e+00 1005.00
IUUC-Apl-003239 Anas platyrhynchos 64.81 0.00e+00 706.00
IUUC-Aca-004756 Anolis carolinensis 61.94 6.00e-141 493.00
IUUC-Ame-011198 Astyanax mexicanus 52.97 1.00e-54 206.00
IUUC-Bta-012430 Bos taurus 56.78 3.00e-150 525.00
IUUC-Cja-019131 Callithrix jacchus 75.87 0.00e+00 874.00
IUUC-Cpo-021898 Cavia porcellus 81.95 0.00e+00 963.00
IUUC-Csa-023452 Chlorocebus sabaeus 79.03 0.00e+00 915.00
IUUC-Cho-024759 Choloepus hoffmanni 72.55 0.00e+00 824.00
IUUC-Dre-028123 Danio rerio 48.83 6.00e-147 514.00
IUUC-Dno-029045 Dasypus novemcinctus 94.48 0.00e+00 899.00
IUUC-Dor-030433 Dipodomys ordii 90.71 0.00e+00 783.00
IUUC-Ete-032465 Echinops telfairi 90.91 0.00e+00 787.00
IUUC-Eca-034134 Equus caballus 95.49 0.00e+00 980.00
IUUC-Eeu-035047 Erinaceus europaeus 83.61 0.00e+00 844.00
IUUC-Fca-036574 Felis catus 95.29 0.00e+00 971.00
IUUC-Fal-037665 Ficedula albicollis 61.69 0.00e+00 628.00
IUUC-Gmo-039137 Gadus morhua 44.40 2.00e-63 236.00
IUUC-Gga-040711 Gallus gallus 64.20 0.00e+00 687.00
IUUC-Gac-041675 Gasterosteus aculeatus 53.76 2.00e-56 211.00
IUUC-Ggo-045331 Gorilla gorilla 87.70 0.00e+00 887.00
IUUC-Hsa-046240 Homo sapiens 78.70 0.00e+00 925.00
IUUC-Itr-048412 Ictidomys tridecemlineatus 94.06 0.00e+00 944.00
IUUC-Loc-052631 Lepisosteus oculatus 54.89 4.00e-170 591.00
IUUC-Laf-054127 Loxodonta africana 81.29 2.00e-62 230.00
IUUC-Mcc-055083 Macaca mulatta 79.53 0.00e+00 921.00
IUUC-Mga-060113 Meleagris gallopavo 64.50 0.00e+00 683.00
IUUC-Mmr-061780 Microcebus murinus 92.14 0.00e+00 958.00
IUUC-Mdo-063066 Monodelphis domestica 68.99 0.00e+00 743.00
IUUC-Mmu-063524 Mus musculus 86.32 0.00e+00 881.00
IUUC-Mpu-066913 Mustela putorius furo 95.61 0.00e+00 995.00
IUUC-Mlu-067924 Myotis lucifugus 82.89 0.00e+00 952.00
IUUC-Nle-069558 Nomascus leucogenys 78.10 0.00e+00 872.00
IUUC-Opr-070506 Ochotona princeps 89.74 0.00e+00 939.00
IUUC-Ont-071514 Oreochromis niloticus 48.05 3.00e-145 508.00
IUUC-Ocu-074477 Oryctolagus cuniculus 90.72 0.00e+00 933.00
IUUC-Ola-087416 Oryzias latipes 48.81 1.00e-144 506.00
IUUC-Oga-088643 Otolemur garnettii 93.21 0.00e+00 979.00
IUUC-Oar-090172 Ovis aries 93.24 0.00e+00 961.00
IUUC-Ptr-090870 Pan troglodytes 79.03 0.00e+00 931.00
IUUC-Pan-092017 Papio anubis 78.54 0.00e+00 906.00
IUUC-Psi-093794 Pelodiscus sinensis 67.21 0.00e+00 700.00
IUUC-Pfo-096192 Poecilia formosa 50.89 2.00e-149 523.00
IUUC-Pab-097882 Pongo abelii 78.20 0.00e+00 914.00
IUUC-Pca-100902 Procavia capensis 72.36 2.00e-135 476.00
IUUC-Pva-103139 Pteropus vampyrus 92.61 0.00e+00 977.00
IUUC-Rno-105798 Rattus norvegicus 85.11 0.00e+00 899.00
IUUC-Sha-106576 Sarcophilus harrisii 69.42 0.00e+00 720.00
IUUC-Ssc-115923 Sus scrofa 75.79 0.00e+00 902.00
IUUC-Tgu-116667 Taeniopygia guttata 57.68 1.00e-122 432.00
IUUC-Tru-118323 Takifugu rubripes 46.67 4.00e-140 491.00
IUUC-Tsy-118818 Tarsius syrichta 77.60 2.00e-109 389.00
IUUC-Tni-120438 Tetraodon nigroviridis 41.95 1.00e-134 473.00
IUUC-Tbe-127784 Tupaia belangeri 95.15 2.00e-114 405.00
IUUC-Ttr-128288 Tursiops truncatus 83.03 0.00e+00 856.00
IUUC-Vpa-130307 Vicugna pacos 89.28 0.00e+00 837.00
Created Date 25-Jun-2017

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