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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Dme-031809
Ensembl Protein ID FBpp0083766
UniProt Accession Q9VCP0; Q86NR0; Q95RH9; ELOA1_DROME
Genbank Protein ID AAF56117.1; AAN13934.1; AAL28911.1; AAO41456.1
Protein Name Transcription elongation factor B polypeptide 3; Elongin-A; RNA polymerase II transcription factor SIII subunit A; dEloA
Genbank Nucleotide ID AE014297; AE014297; AY061363; BT003775
Gene Name EloA; CG6755
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
FBgn0039066 FBtr0084374 FBpp0083766
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpress
DNA & RNA Element
microRNARAID2
Protein-protein Interaction
IIDPINAMentha
Post-translational Modifications (PTMs)
dbPAFdbPTMPhospho.ELMUniProt
PHOSIDA
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
E3 adaptor/Cullin RING/SCF/F-box 26.51 2.00e-04 42.40 IUUC-Sce-106376
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box 26.51 2.00e-04 42.40 IUUC-Sce-106376
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Drosophila melanogaster
Functional Description
(View)

Functional Description


     SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A is transcriptionally active and its transcription activity is strongly enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex). May play an important role in metamorphosis.
 SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A is transcriptionally active and its transcription activity is strongly enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex). May play an important role in metamorphosis.
Protein Sequence
(Fasta)
MASTSNLLDV VRHYQRSIEK HGEDEQRLLH CITKLFNLPI KFEHLQETGI GKTVNALRKI 60
SGEVGVAAKT LVTKWKAMVA KEDPSIASTP TAIHNEEDSG KTKSSDEDPD QENKGGNSSS 120
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Protein Fasta Sequence


>IUUC-Dme-031809|E3,F-box;E3,SOCS|Drosophila melanogaster
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CCGTCAAAAG CAAATCTCAT TTAGTTTCCA ACGCTGCTGG CCTGGCAAAA GCAAAAATCG 60
AATGTATTAT AATAAAGGCC CGTAATGCTA TTGAAAATAA CTTAGAGCCT CGCGACCAGA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Dme-031809|E3,F-box;E3,SOCS|Drosophila melanogaster
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0217--Developmental protein
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation
Interpro

IPR010684--RNA_pol_II_trans_fac_SIII_A
IPR003617--TFIIS/CRSP70_N_sub
IPR017923--TFIIS_N
PROSITE

PS51319--TFIIS_N
Pfam

PF06881--Elongin_A
PF08711--Med26
SMART

SM00509--TFS2N
Gene Ontology

GO:0070449--C:elongin complex
GO:0016021--C:integral component of membrane
GO:0005634--C:nucleus
GO:0008023--C:transcription elongation factor complex
GO:0007474--P:imaginal disc-derived wing vein specification
GO:0032968--P:positive regulation of transcription elongation from RNA polymerase II promoter
GO:0006368--P:transcription elongation from RNA polymerase II promoter
KEGG dme:Dmel_CG6755
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001705 Ailuropoda melanoleuca 32.99 3.00e-35 142.00
IUUC-Apl-003659 Anas platyrhynchos 33.90 1.00e-43 171.00
IUUC-Aca-004513 Anolis carolinensis 37.33 2.00e-38 153.00
IUUC-Ago-007835 Ashbya gossypii 37.70 2.00e-06 45.80
IUUC-Acl-008085 Aspergillus clavatus 25.69 3.00e-09 55.50
IUUC-Afu-008931 Aspergillus fumigatus 27.36 3.00e-08 52.00
IUUC-Ani-009161 Aspergillus nidulans 27.36 2.00e-08 52.80
IUUC-Ang-009875 Aspergillus niger 27.78 6.00e-09 54.30
IUUC-Ame-011668 Astyanax mexicanus 36.73 5.00e-33 135.00
IUUC-Bta-013219 Bos taurus 29.93 3.00e-32 133.00
IUUC-Bci-014000 Botrytis cinerea 23.73 5.00e-06 44.70
IUUC-Bol-016438 Brassica oleracea 29.59 4.00e-08 51.60
IUUC-Bra-017526 Brassica rapa 30.61 6.00e-09 54.30
IUUC-Cel-018281 Caenorhabditis elegans 30.00 1.00e-17 83.60
IUUC-Cja-018759 Callithrix jacchus 31.03 2.00e-30 127.00
IUUC-Cfa-020766 Canis familiaris 33.22 1.00e-34 140.00
IUUC-Cpo-022250 Cavia porcellus 35.14 7.00e-38 151.00
IUUC-Csa-023293 Chlorocebus sabaeus 31.72 1.00e-33 137.00
IUUC-Cin-025556 Ciona intestinalis 35.08 3.00e-38 152.00
IUUC-Csv-026153 Ciona savignyi 37.09 1.00e-31 128.00
IUUC-Cgl-026733 Colletotrichum gloeosporioides 29.87 6.00e-05 41.20
IUUC-Cne-026936 Cryptococcus neoformans 21.97 6.00e-05 41.20
IUUC-Dre-027828 Danio rerio 39.38 1.00e-38 153.00
IUUC-Dse-031436 Dothistroma septosporum 22.94 4.00e-04 38.50
IUUC-Ete-032677 Echinops telfairi 33.11 3.00e-40 159.00
IUUC-Eca-034045 Equus caballus 36.88 2.00e-30 126.00
IUUC-Eeu-035063 Erinaceus europaeus 38.57 4.00e-34 139.00
IUUC-Fca-036488 Felis catus 32.99 6.00e-33 135.00
IUUC-Fal-037501 Ficedula albicollis 34.24 3.00e-43 169.00
IUUC-Fso-038123 Fusarium solani 33.85 1.00e-05 43.50
IUUC-Gmo-038614 Gadus morhua 43.83 2.00e-32 133.00
IUUC-Ggr-039793 Gaeumannomyces graminis 27.17 2.00e-06 46.20
IUUC-Gga-040738 Gallus gallus 33.90 3.00e-42 166.00
IUUC-Gac-041381 Gasterosteus aculeatus 37.20 6.00e-40 158.00
IUUC-Gma-042964 Glycine max 31.08 7.00e-03 33.10
IUUC-Ggo-045139 Gorilla gorilla 31.72 1.00e-33 137.00
IUUC-Hsa-046083 Homo sapiens 32.41 1.00e-33 137.00
IUUC-Itr-048970 Ictidomys tridecemlineatus 32.99 4.00e-35 142.00
IUUC-Kpa-049376 Komagataella pastoris 28.12 3.00e-05 41.20
IUUC-Lch-050369 Latimeria chalumnae 38.65 5.00e-36 145.00
IUUC-Loc-052347 Lepisosteus oculatus 45.79 1.00e-26 114.00
IUUC-Lma-053027 Leptosphaeria maculans 34.38 5.80e-02 30.80
IUUC-Laf-053575 Loxodonta africana 31.62 8.00e-33 134.00
IUUC-Mcc-054823 Macaca mulatta 31.72 9.00e-34 137.00
IUUC-Meu-056878 Macropus eugenii 36.26 6.00e-31 127.00
IUUC-Mor-056948 Magnaporthe oryzae 30.77 1.00e-06 46.60
IUUC-Mtr-057811 Medicago truncatula 25.74 1.70e-01 28.50
IUUC-Mla-058917 Melampsora laricipopulina 37.29 5.00e-08 51.20
IUUC-Mga-059445 Meleagris gallopavo 33.90 1.00e-42 167.00
IUUC-Mmr-060665 Microcebus murinus 33.45 5.00e-34 139.00
IUUC-Mdo-062430 Monodelphis domestica 38.83 5.00e-39 155.00
IUUC-Mmu-064173 Mus musculus 31.72 5.00e-33 135.00
IUUC-Mac-065364 Musa acuminata 20.00 6.00e-03 33.50
IUUC-Mpu-066344 Mustela putorius furo 53.33 3.00e-06 47.00
IUUC-Mlu-068101 Myotis lucifugus 32.76 7.00e-35 141.00
IUUC-Nfi-068489 Neosartorya fischeri 26.42 7.00e-08 50.80
IUUC-Opr-070498 Ochotona princeps 38.61 3.00e-18 85.50
IUUC-Ont-071579 Oreochromis niloticus 31.72 2.00e-30 126.00
IUUC-Oan-072862 Ornithorhynchus anatinus 36.40 4.00e-43 169.00
IUUC-Ocu-073882 Oryctolagus cuniculus 39.05 2.00e-35 142.00
IUUC-Ola-086456 Oryzias latipes 33.11 9.00e-35 141.00
IUUC-Oga-087918 Otolemur garnettii 36.36 7.00e-34 138.00
IUUC-Oar-089663 Ovis aries 33.22 5.00e-41 161.00
IUUC-Ptr-091033 Pan troglodytes 36.84 7.00e-34 138.00
IUUC-Pan-092277 Papio anubis 36.36 1.00e-33 137.00
IUUC-Psi-094086 Pelodiscus sinensis 33.56 5.00e-42 165.00
IUUC-Pma-094683 Petromyzon marinus 40.57 2.00e-22 99.00
IUUC-Pno-094930 Phaeosphaeria nodorum 31.36 6.00e-10 57.40
IUUC-Pfo-097334 Poecilia formosa 36.87 6.00e-34 138.00
IUUC-Pab-098345 Pongo abelii 36.36 9.00e-34 137.00
IUUC-Pop-099683 Populus trichocarpa 34.04 4.00e-03 32.30
IUUC-Pca-100737 Procavia capensis 33.11 2.00e-34 140.00
IUUC-Pva-102497 Pteropus vampyrus 38.29 1.00e-36 147.00
IUUC-Pgr-103464 Puccinia graminis 38.81 2.00e-09 54.30
IUUC-Pte-104288 Pyrenophora teres 30.00 1.00e-05 42.70
IUUC-Pyt-104772 Pyrenophora triticirepentis 30.00 5.00e-05 40.80
IUUC-Rno-105177 Rattus norvegicus 31.40 5.00e-33 135.00
IUUC-Sce-106376 Saccharomyces cerevisiae 26.51 2.00e-05 42.70
IUUC-Sha-106480 Sarcophilus harrisii 33.22 8.00e-40 157.00
IUUC-Sja-107782 Schizosaccharomyces japonicus 28.18 2.00e-12 65.10
IUUC-Spo-108157 Schizosaccharomyces pombe 29.91 8.00e-13 65.90
IUUC-Sit-109960 Setaria italica 32.52 3.00e-05 41.20
IUUC-Sar-113255 Sorex araneus 40.48 2.00e-32 133.00
IUUC-Sre-115076 Sporisorium reilianum 28.18 5.00e-12 65.10
IUUC-Ssc-115875 Sus scrofa 33.11 2.00e-41 163.00
IUUC-Tgu-117066 Taeniopygia guttata 39.82 2.00e-42 166.00
IUUC-Tru-117881 Takifugu rubripes 33.55 5.00e-33 134.00
IUUC-Tsy-119531 Tarsius syrichta 34.93 8.00e-37 148.00
IUUC-Tni-120325 Tetraodon nigroviridis 33.33 3.00e-43 169.00
IUUC-Tae-122727 Triticum aestivum 38.46 4.00e-06 44.70
IUUC-Tur-126506 Triticum urartu 38.46 1.00e-05 42.70
IUUC-Tbe-127648 Tupaia belangeri 37.80 7.00e-34 138.00
IUUC-Ttr-129287 Tursiops truncatus 34.60 1.00e-41 164.00
IUUC-Uma-129543 Ustilago maydis 33.33 7.00e-10 58.20
IUUC-Vpa-130645 Vicugna pacos 37.14 2.00e-39 156.00
IUUC-Xtr-132709 Xenopus tropicalis 43.04 5.00e-09 55.50
IUUC-Xma-133858 Xiphophorus maculatus 37.67 5.00e-34 138.00
IUUC-Yli-134386 Yarrowia lipolytica 26.76 4.00e-11 61.20
IUUC-Zma-135412 Zea mays 35.35 4.00e-05 40.80
Created Date 25-Jun-2017

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