iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mga-059498

UUCD1 version

UUC-MeG-00738

Ensembl Protein ID

ENSMGAP00000018535.1

UniProt Accession

G3US64; G3US64_MELGA

Protein Name

Uncharacterized protein

Gene Name

RFWD3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000016799.1	ENSMGAT00000018558.1	ENSMGAP00000018535.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	5.90e-06	26.4	139	183
E3 adaptor/Cullin RING/DCX/DWD	2.70e-08	33.6	395	426

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf.....kdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           CaiC+e+         +  l+CgH+f  +C+ +w     ++ ++ +CP C+
   Q: 139  CAICFEPWtnageH-RLSALRCGHLFGYTCIDRW-----LKGQAGKCPQCN 183
           ********777633.38889**************.....4555559***96 PP

E3 adaptor/Cullin RING/DCX/DWD

   S: 4    dsvtclaf..sd.tllvsGsdDgtikvWDlrt 32
            +v+++++  +d +++ +G  +g+i+++Dlr+
   Q: 395  RPVWSCCWclDDtNYIYAGLVNGSIMIYDLRD 426
           68*******9888****************997 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

QRPRVRRGAR RQPRVSGSQR TVSARCRAAL DSYFQISRTQ EPATIAGSHL EPSHTVRSSQ 60
EHTSQVTELQ LSDTDSSTSE EEEEDQAELP QTLPQVPAER GNREDEEFEA QQKQRTPLKK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGCGCCCGC GGGTACGAAG GGGTGCTCGC AGGCAGCCGA GAGTCAGTGG TTCCCAGAGG 60
ACAGTCAGTG CCAGGTAAAG CAGGACTGAA GCTGTGTCTG AGCTGTGCCC TTACCGGCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF13639--zf-RING_2

SMART

SM00184--RING
SM00320--WD40

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0035861--C:site of double-strand break
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0031571--P:mitotic G1 DNA damage checkpoint
GO:2000001--P:regulation of DNA damage checkpoint
GO:0010212--P:response to ionizing radiation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000929	Aegilops tauschii	23.42	1.00e-15	77.40
IUUC-Aml-001188	Ailuropoda melanoleuca	62.44	0.00e+00	714.00
IUUC-Atr-003034	Amborella trichopoda	28.93	3.00e-17	82.00
IUUC-Apl-003182	Anas platyrhynchos	75.99	0.00e+00	875.00
IUUC-Aca-004619	Anolis carolinensis	75.10	0.00e+00	784.00
IUUC-Aly-006391	Arabidopsis lyrata	26.87	1.00e-31	130.00
IUUC-Ath-007300	Arabidopsis thaliana	25.33	9.00e-33	134.00
IUUC-Ame-010890	Astyanax mexicanus	62.70	0.00e+00	659.00
IUUC-Bta-013051	Bos taurus	59.10	0.00e+00	691.00
IUUC-Bdi-014519	Brachypodium distachyon	23.76	5.00e-21	95.50
IUUC-Bol-015271	Brassica oleracea	28.95	9.00e-32	131.00
IUUC-Bra-017931	Brassica rapa	28.43	2.00e-31	129.00
IUUC-Cja-019240	Callithrix jacchus	58.53	0.00e+00	710.00
IUUC-Cfa-021010	Canis familiaris	59.55	0.00e+00	691.00
IUUC-Cpo-022308	Cavia porcellus	58.85	0.00e+00	679.00
IUUC-Csa-023501	Chlorocebus sabaeus	61.43	0.00e+00	712.00
IUUC-Cho-024900	Choloepus hoffmanni	53.82	4.00e-173	600.00
IUUC-Cin-025403	Ciona intestinalis	36.51	3.00e-90	325.00
IUUC-Csv-025819	Ciona savignyi	36.92	1.00e-44	172.00
IUUC-Cme-027123	Cyanidioschyzon merolae	24.58	2.00e-16	80.50
IUUC-Dre-028354	Danio rerio	58.38	1.00e-171	596.00
IUUC-Dno-029400	Dasypus novemcinctus	61.70	0.00e+00	708.00
IUUC-Dor-030320	Dipodomys ordii	53.88	4.00e-171	594.00
IUUC-Dme-031949	Drosophila melanogaster	24.56	3.00e-31	129.00
IUUC-Ete-032691	Echinops telfairi	50.00	5.00e-89	321.00
IUUC-Eca-034320	Equus caballus	61.92	0.00e+00	720.00
IUUC-Fca-035732	Felis catus	62.34	0.00e+00	720.00
IUUC-Fal-036648	Ficedula albicollis	82.76	0.00e+00	832.00
IUUC-Gmo-038609	Gadus morhua	58.63	6.00e-144	503.00
IUUC-Gga-040522	Gallus gallus	75.45	3.00e-146	511.00
IUUC-Gac-042318	Gasterosteus aculeatus	57.76	3.00e-141	494.00
IUUC-Gma-043184	Glycine max	41.77	1.00e-15	77.80
IUUC-Ggo-044464	Gorilla gorilla	62.07	0.00e+00	719.00
IUUC-Hsa-045991	Homo sapiens	61.91	0.00e+00	717.00
IUUC-Hvu-047705	Hordeum vulgare	24.44	7.00e-26	111.00
IUUC-Itr-047977	Ictidomys tridecemlineatus	61.20	0.00e+00	703.00
IUUC-Lch-050112	Latimeria chalumnae	66.73	0.00e+00	704.00
IUUC-Lpe-051605	Leersia perrieri	24.80	7.00e-18	85.10
IUUC-Loc-052241	Lepisosteus oculatus	64.37	0.00e+00	661.00
IUUC-Laf-054559	Loxodonta africana	59.31	6.00e-178	617.00
IUUC-Mcc-055093	Macaca mulatta	61.46	0.00e+00	714.00
IUUC-Meu-056417	Macropus eugenii	69.91	3.00e-141	494.00
IUUC-Mtr-058533	Medicago truncatula	24.52	4.00e-31	129.00
IUUC-Mmr-061782	Microcebus murinus	60.86	0.00e+00	693.00
IUUC-Mdo-062053	Monodelphis domestica	70.36	0.00e+00	706.00
IUUC-Mmu-063352	Mus musculus	64.06	0.00e+00	656.00
IUUC-Mac-064582	Musa acuminata	28.12	7.00e-26	111.00
IUUC-Mpu-066087	Mustela putorius furo	61.80	0.00e+00	706.00
IUUC-Mlu-068147	Myotis lucifugus	65.93	0.00e+00	668.00
IUUC-Nle-069503	Nomascus leucogenys	58.18	0.00e+00	660.00
IUUC-Opr-070479	Ochotona princeps	55.70	0.00e+00	627.00
IUUC-Ont-071700	Oreochromis niloticus	61.12	5.00e-179	620.00
IUUC-Oan-073702	Ornithorhynchus anatinus	73.64	0.00e+00	752.00
IUUC-Ocu-074886	Oryctolagus cuniculus	59.84	0.00e+00	692.00
IUUC-Oba-075729	Oryza barthii	26.38	3.00e-28	119.00
IUUC-Obr-076562	Oryza brachyantha	25.62	1.00e-21	97.40
IUUC-Ogl-077615	Oryza glaberrima	26.38	3.00e-28	119.00
IUUC-Ogu-078921	Oryza glumaepatula	26.38	6.00e-29	122.00
IUUC-Oin-079250	Oryza indica	23.94	5.00e-18	85.50
IUUC-Olo-080758	Oryza longistaminata	26.12	8.00e-27	114.00
IUUC-Ome-081707	Oryza meridionalis	24.95	4.00e-21	95.90
IUUC-Oni-083006	Oryza nivara	26.38	1.00e-28	120.00
IUUC-Opu-083650	Oryza punctata	25.49	1.00e-27	117.00
IUUC-Oru-084924	Oryza rufipogon	26.44	2.00e-29	123.00
IUUC-Osa-085820	Oryza sativa	26.16	1.00e-28	120.00
IUUC-Ola-087229	Oryzias latipes	60.81	1.00e-144	505.00
IUUC-Oga-088243	Otolemur garnettii	61.61	0.00e+00	698.00
IUUC-Oar-089461	Ovis aries	61.01	0.00e+00	701.00
IUUC-Ptr-090527	Pan troglodytes	61.91	0.00e+00	712.00
IUUC-Pan-092431	Papio anubis	60.92	0.00e+00	644.00
IUUC-Psi-093156	Pelodiscus sinensis	69.75	0.00e+00	831.00
IUUC-Ppa-095305	Physcomitrella patens	44.34	3.00e-20	94.00
IUUC-Pfo-097065	Poecilia formosa	60.24	3.00e-172	598.00
IUUC-Pab-098272	Pongo abelii	61.75	0.00e+00	717.00
IUUC-Pop-099827	Populus trichocarpa	47.62	1.00e-17	84.00
IUUC-Pca-100713	Procavia capensis	52.94	7.00e-174	603.00
IUUC-Ppe-102103	Prunus persica	27.25	6.00e-33	135.00
IUUC-Pva-103133	Pteropus vampyrus	64.44	1.00e-155	543.00
IUUC-Sha-107628	Sarcophilus harrisii	68.03	0.00e+00	702.00
IUUC-Sit-109891	Setaria italica	25.34	3.00e-28	119.00
IUUC-Sly-111779	Solanum lycopersicum	28.16	5.00e-30	125.00
IUUC-Stu-112817	Solanum tuberosum	44.63	3.00e-21	94.70
IUUC-Sar-113124	Sorex araneus	53.85	2.00e-126	446.00
IUUC-Sbi-114107	Sorghum bicolor	25.09	4.00e-28	119.00
IUUC-Ssc-115850	Sus scrofa	61.34	0.00e+00	689.00
IUUC-Tgu-117295	Taeniopygia guttata	80.73	0.00e+00	839.00
IUUC-Tru-117539	Takifugu rubripes	60.52	3.00e-175	607.00
IUUC-Tsy-118805	Tarsius syrichta	52.51	3.00e-79	288.00
IUUC-Tni-120274	Tetraodon nigroviridis	60.56	2.00e-178	617.00
IUUC-Tca-121162	Theobroma cacao	28.78	2.00e-30	127.00
IUUC-Tae-124822	Triticum aestivum	24.42	4.00e-26	112.00
IUUC-Tur-126162	Triticum urartu	23.61	2.00e-18	87.00
IUUC-Tbe-127884	Tupaia belangeri	53.81	9.00e-54	204.00
IUUC-Ttr-128665	Tursiops truncatus	71.83	9.00e-110	390.00
IUUC-Vpa-130385	Vicugna pacos	62.24	0.00e+00	718.00
IUUC-Vvi-131464	Vitis vinifera	34.51	1.00e-15	77.80
IUUC-Xtr-132015	Xenopus tropicalis	61.79	0.00e+00	726.00
IUUC-Xma-133109	Xiphophorus maculatus	60.64	7.00e-170	590.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence