iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ggo-045141

UUCD1 version

UUC-GoG-00619

Ensembl Protein ID

ENSGGOP00000015462.2

UniProt Accession

G3RIG0; G3RIG0_GORGO

Protein Name

Uncharacterized protein

Gene Name

KLHL22

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000015856.2	ENSGGOT00000015907.2	ENSGGOP00000015462.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	5.30e-11	43.2	51	113
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	5.80e-08	32.0	150	179

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 2    DvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkl 65
           Dv+lvv+g++++ah+i Laas+++F+  +    +  k +++v+i++v+  ++  l++F Yt+++
   Q: 51   DVVLVVEGRHIEAHRILLAASCDYFRGVCVWSRRPIK-SSEVKIRGVKQNAMCLLISFKYTSRI 113
           9****************************99999999.***********************997 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 2    eNclgilrfAdlydcpdLkdaaldfilkhF 31
           eN l+++r+A+l+d+++L ++ +++ilk+F
   Q: 150  ENILDVYRLAELFDLSRLTEQLDTYILKNF 179
           8***************************** PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

MAEEQEFTQL CKLPAQPSHP HCVNNTYRSA QHSQALLRGL LALRDSGILF DVVLVVEGRH 60
IEAHRILLAA SCDYFRGVCV WSRRPIKSSE VKIRGVKQNA MCLLISFKYT SRIIPCVMNI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGAGG AGCAGGAGTT CACCCAGCTC TGCAAGTTGC CTGCACAGCC CTCCCACCCA 60
CACTGCGTGA ACAACACCTA CCGCAGCGCA CAGCACTCCC AGGCTCTGCT CCGAGGGCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030575--KLHL22
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0005813--C:centrosome
GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0072686--C:mitotic spindle
GO:0005827--C:polar microtubule
GO:0051301--P:cell division
GO:0000070--P:mitotic sister chromatid segregation
GO:0007094--P:mitotic spindle assembly checkpoint
GO:0006513--P:protein monoubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002097	Ailuropoda melanoleuca	92.11	0.00e+00	1160.00
IUUC-Apl-004081	Anas platyrhynchos	73.82	0.00e+00	968.00
IUUC-Aca-005015	Anolis carolinensis	62.44	0.00e+00	800.00
IUUC-Ame-011712	Astyanax mexicanus	56.68	0.00e+00	672.00
IUUC-Bta-012594	Bos taurus	88.33	0.00e+00	1149.00
IUUC-Cja-019752	Callithrix jacchus	99.01	0.00e+00	1044.00
IUUC-Cfa-020884	Canis familiaris	92.59	0.00e+00	1202.00
IUUC-Cpo-021711	Cavia porcellus	91.48	0.00e+00	1191.00
IUUC-Csa-023211	Chlorocebus sabaeus	94.01	0.00e+00	1217.00
IUUC-Dre-028395	Danio rerio	56.36	0.00e+00	700.00
IUUC-Dno-030096	Dasypus novemcinctus	88.40	0.00e+00	1148.00
IUUC-Dor-030709	Dipodomys ordii	86.22	0.00e+00	632.00
IUUC-Eca-033388	Equus caballus	92.43	0.00e+00	1200.00
IUUC-Eeu-034616	Erinaceus europaeus	86.44	0.00e+00	1104.00
IUUC-Fca-035815	Felis catus	92.43	0.00e+00	1200.00
IUUC-Fal-037311	Ficedula albicollis	75.93	0.00e+00	949.00
IUUC-Gmo-039571	Gadus morhua	49.13	1.00e-142	499.00
IUUC-Gga-040992	Gallus gallus	73.67	0.00e+00	969.00
IUUC-Gac-042041	Gasterosteus aculeatus	52.42	0.00e+00	635.00
IUUC-Hsa-045984	Homo sapiens	94.16	0.00e+00	1220.00
IUUC-Itr-048890	Ictidomys tridecemlineatus	92.59	0.00e+00	1204.00
IUUC-Lch-049700	Latimeria chalumnae	55.96	0.00e+00	663.00
IUUC-Loc-052141	Lepisosteus oculatus	58.20	0.00e+00	759.00
IUUC-Laf-053487	Loxodonta africana	89.84	0.00e+00	1152.00
IUUC-Mcc-054682	Macaca mulatta	92.41	0.00e+00	962.00
IUUC-Meu-055937	Macropus eugenii	74.76	0.00e+00	964.00
IUUC-Mga-059953	Meleagris gallopavo	73.67	0.00e+00	969.00
IUUC-Mmr-061743	Microcebus murinus	92.11	0.00e+00	1190.00
IUUC-Mdo-062328	Monodelphis domestica	77.90	0.00e+00	1021.00
IUUC-Mmu-063979	Mus musculus	88.68	0.00e+00	1140.00
IUUC-Mpu-066750	Mustela putorius furo	92.43	0.00e+00	1199.00
IUUC-Mlu-066960	Myotis lucifugus	90.22	0.00e+00	1165.00
IUUC-Nle-069690	Nomascus leucogenys	94.37	0.00e+00	1086.00
IUUC-Opr-071059	Ochotona princeps	84.57	0.00e+00	1075.00
IUUC-Ont-072004	Oreochromis niloticus	54.81	0.00e+00	633.00
IUUC-Oan-073172	Ornithorhynchus anatinus	59.11	0.00e+00	684.00
IUUC-Ocu-074310	Oryctolagus cuniculus	96.59	3.00e-155	540.00
IUUC-Ola-086599	Oryzias latipes	54.31	0.00e+00	646.00
IUUC-Oga-087980	Otolemur garnettii	91.48	0.00e+00	1183.00
IUUC-Oar-089956	Ovis aries	73.13	0.00e+00	840.00
IUUC-Ptr-090598	Pan troglodytes	93.20	0.00e+00	1087.00
IUUC-Pan-092387	Papio anubis	92.02	0.00e+00	962.00
IUUC-Psi-093484	Pelodiscus sinensis	74.76	0.00e+00	994.00
IUUC-Pma-094224	Petromyzon marinus	46.64	1.00e-157	549.00
IUUC-Pfo-096149	Poecilia formosa	53.73	0.00e+00	654.00
IUUC-Pab-098097	Pongo abelii	94.01	0.00e+00	1220.00
IUUC-Pca-100118	Procavia capensis	85.41	2.00e-180	625.00
IUUC-Pva-103174	Pteropus vampyrus	96.58	5.00e-156	544.00
IUUC-Rno-105350	Rattus norvegicus	88.96	0.00e+00	1127.00
IUUC-Sha-106817	Sarcophilus harrisii	83.15	4.00e-134	471.00
IUUC-Sar-113490	Sorex araneus	85.42	5.00e-165	574.00
IUUC-Ssc-115827	Sus scrofa	90.38	0.00e+00	1177.00
IUUC-Tgu-116748	Taeniopygia guttata	77.57	0.00e+00	845.00
IUUC-Tru-118644	Takifugu rubripes	54.59	0.00e+00	642.00
IUUC-Tsy-118888	Tarsius syrichta	85.66	0.00e+00	979.00
IUUC-Tni-120060	Tetraodon nigroviridis	50.87	3.00e-159	555.00
IUUC-Ttr-129183	Tursiops truncatus	89.25	0.00e+00	1043.00
IUUC-Xtr-132780	Xenopus tropicalis	64.50	0.00e+00	844.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence