iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Sha-107033

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEFK01171771

Gene Name

RNF146

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000018661.1	ENSSHAT00000022222.1	ENSSHAP00000022046.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	88.61	2.00e-154	542.00	IUUC-Hsa-045790

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

RMAGCGEIDH TINMLPTNRK ANESCSNAGP SLTVPECAIC LQTCVHPVSL PCKHVFCYLC 60
VKGASWLGKR CALCRQEIPE DFLDKPTLLS PEELKAASRG NGEYAWYYEG RNGWWQYDER 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGGATGGCTG GCTGTGGTGA AATTGATCAC ACAATAAACA TGCTTCCCAC GAACAGAAAG 60
GCAAATGAGT CCTGTTCTAA TGCTGGACCT TCTCTTACTG TCCCTGAATG TGCCATCTGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR033509--RNF146
IPR004170--WWE-dom
IPR018123--WWE-dom_subgr
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50918--WWE
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF02825--WWE

SMART

SM00184--RING
SM00678--WWE

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0005886--C:plasma membrane
GO:0072572--F:poly-ADP-D-ribose binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0090263--P:positive regulation of canonical Wnt signaling pathway
GO:0051865--P:protein autoubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0016055--P:Wnt signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002237	Ailuropoda melanoleuca	86.70	7.00e-143	499.00
IUUC-Apl-004143	Anas platyrhynchos	87.25	1.00e-136	478.00
IUUC-Aca-004557	Anolis carolinensis	85.03	2.00e-136	478.00
IUUC-Ame-011088	Astyanax mexicanus	59.85	7.00e-83	300.00
IUUC-Bta-012639	Bos taurus	88.35	1.00e-142	499.00
IUUC-Cel-018462	Caenorhabditis elegans	28.35	5.00e-19	87.40
IUUC-Cja-019397	Callithrix jacchus	87.78	3.00e-144	504.00
IUUC-Cfa-021140	Canis familiaris	86.11	2.00e-150	525.00
IUUC-Cpo-021387	Cavia porcellus	84.64	3.00e-155	540.00
IUUC-Csa-023503	Chlorocebus sabaeus	90.06	2.00e-143	501.00
IUUC-Cho-024895	Choloepus hoffmanni	85.25	7.00e-128	449.00
IUUC-Cin-025455	Ciona intestinalis	53.29	3.00e-43	167.00
IUUC-Dre-028824	Danio rerio	48.68	3.00e-86	311.00
IUUC-Dno-029269	Dasypus novemcinctus	86.43	1.00e-146	511.00
IUUC-Dor-030592	Dipodomys ordii	85.28	1.00e-149	522.00
IUUC-Dme-031618	Drosophila melanogaster	58.00	5.00e-56	211.00
IUUC-Ete-032478	Echinops telfairi	86.83	4.00e-151	526.00
IUUC-Eca-033389	Equus caballus	89.08	2.00e-163	568.00
IUUC-Fca-035488	Felis catus	89.66	7.00e-149	519.00
IUUC-Fal-037087	Ficedula albicollis	86.12	1.00e-159	555.00
IUUC-Gga-040401	Gallus gallus	87.78	4.00e-143	500.00
IUUC-Gac-042412	Gasterosteus aculeatus	65.79	2.00e-88	318.00
IUUC-Ggo-045417	Gorilla gorilla	90.97	6.00e-142	496.00
IUUC-Hsa-045790	Homo sapiens	87.78	6.00e-144	503.00
IUUC-Itr-048820	Ictidomys tridecemlineatus	87.99	1.00e-152	532.00
IUUC-Lch-049493	Latimeria chalumnae	71.43	1.00e-115	409.00
IUUC-Loc-052927	Lepisosteus oculatus	62.77	2.00e-105	375.00
IUUC-Laf-053904	Loxodonta africana	86.70	2.00e-150	524.00
IUUC-Mcc-055427	Macaca mulatta	86.67	5.00e-145	506.00
IUUC-Mmr-060580	Microcebus murinus	89.39	2.00e-145	508.00
IUUC-Mdo-062094	Monodelphis domestica	99.24	2.00e-79	286.00
IUUC-Mmu-063363	Mus musculus	85.00	6.00e-149	520.00
IUUC-Mpu-066816	Mustela putorius furo	87.53	2.00e-143	501.00
IUUC-Mlu-067433	Myotis lucifugus	88.09	6.00e-166	576.00
IUUC-Nle-068986	Nomascus leucogenys	87.22	2.00e-156	544.00
IUUC-Ont-072670	Oreochromis niloticus	66.22	9.00e-82	296.00
IUUC-Oan-073330	Ornithorhynchus anatinus	87.06	9.00e-107	379.00
IUUC-Ocu-074161	Oryctolagus cuniculus	88.92	5.00e-155	540.00
IUUC-Ola-086902	Oryzias latipes	60.87	6.00e-86	310.00
IUUC-Oga-089159	Otolemur garnettii	88.45	1.00e-166	578.00
IUUC-Oar-089586	Ovis aries	87.11	2.00e-133	468.00
IUUC-Ptr-090987	Pan troglodytes	87.78	6.00e-144	503.00
IUUC-Pan-091867	Papio anubis	86.70	2.00e-145	508.00
IUUC-Psi-094024	Pelodiscus sinensis	88.10	2.00e-148	518.00
IUUC-Pma-094453	Petromyzon marinus	63.53	3.00e-65	241.00
IUUC-Pfo-097108	Poecilia formosa	52.37	1.00e-86	313.00
IUUC-Pab-097997	Pongo abelii	86.94	1.00e-148	518.00
IUUC-Pca-100260	Procavia capensis	86.55	2.00e-150	525.00
IUUC-Pva-103140	Pteropus vampyrus	87.50	2.00e-155	541.00
IUUC-Rno-105795	Rattus norvegicus	80.85	2.00e-148	518.00
IUUC-Ssc-116395	Sus scrofa	88.64	2.00e-168	584.00
IUUC-Tgu-116685	Taeniopygia guttata	84.99	3.00e-141	494.00
IUUC-Tru-118014	Takifugu rubripes	64.23	1.00e-83	302.00
IUUC-Tsy-119326	Tarsius syrichta	81.84	7.00e-160	556.00
IUUC-Tni-120322	Tetraodon nigroviridis	67.61	2.00e-81	295.00
IUUC-Tbe-128067	Tupaia belangeri	87.22	1.00e-152	532.00
IUUC-Ttr-128530	Tursiops truncatus	87.78	3.00e-150	524.00
IUUC-Vpa-130322	Vicugna pacos	88.89	5.00e-155	540.00
IUUC-Xtr-132606	Xenopus tropicalis	69.12	4.00e-121	427.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence